• 2023
    • Bruninx, A., Geraeds, C., Brunner-La Rocca, H., Dekker, A., & Bermejo, I. (2023). Modelling clinicians' decisions to adjust loop diuretic dose based on patient-reported symptoms to inform decision-aids in daily care of chronic heart failure. European Heart Journal, 44.
    • Babu, V. S., Mallipatna, A., Dudeja, G., Shetty, R., Nair, A. P., Tun, S. B. B., Ho, C. E. H., Chaurasia, S. S., Bhattacharya, S. S., Verma, N. K., Lakshminarayanan, R., Guha, N., Heymans, S., Barathi, V. A., & Ghosh, A. (2023). Depleted hexokinase1 and lack of AMPKα activation favor OXPHOS-dependent energetics in retinoblastoma tumors. Translational Research, 261(1), 41-56. https://doi.org/10.1016/j.trsl.2023.07.001
    • Sikking, M. A., Stroeks, S. L. V. M., Marelli-Berg, F., Heymans, S. R. B., Ludewig, B., & Verdonschot, J. A. J. (2023). Immunomodulation of Myocardial Fibrosis. JACC: Basic to Translational Science, 8(11), 1477-1488. https://doi.org/10.1016/j.jacbts.2023.03.015
    • Seferovic, P. M., Polovina, M., Rosano, G., Bozkurt, B., Metra, M., Heymans, S., Mullens, W., Bauersachs, J., Sliwa, K., de Boer, R. A., Farmakis, D., Thum, T., Olivotto, I., Rapezzi, C., Linhart, A., Corrado, D., Tschöpe, C., Milinkovic, I., Bayes Genis, A., ... Coats, A. J. (2023). State-of-the-art document on optimal contemporary management of cardiomyopathies. European journal of heart failure, 25(11), 1899-1922. Article ejhf2979. https://doi.org/10.1002/ejhf.2979
    • Michelly Gonçalves Brandão, S., Brunner-La Rocca, H. P., Pedroso De Lima, A. C., & Alcides Bocchi, E. (2023). A review of cost-effectiveness analysis: From theory to clinical practice. Medicine, 102(42), Article e35614. https://doi.org/10.1097/MD.0000000000035614
    • McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Böhm, M., Burri, H., Butler, J., Celutkiene, J., Chioncel, O., Cleland, J. G. F., Crespo-Leiro, M. G., Farmakis, D., Gilard, M., Heymans, S., Hoes, A. W., Jaarsma, T., Jankowska, E. A., Lainscak, M., ... ESC Scientific Document Group (2023). 2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure Developed by the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC. European Heart Journal, 44(37), 3627-3639. https://doi.org/10.1093/eurheartj/ehad195
    • Cerqueira, R., Moreira-Costa, L., Beslika, E., Leite-Moreira, A., Silva, J., da Costa Martins, P. A., Leite-Moreira, A., Lourenço, A., & Mendes-Ferreira, P. (2023). A Minimally Invasive Model of Aortic Stenosis in Swine. Journal of visualized experiment, 2003(200), Article e65780. https://doi.org/10.3791/65780
    • Heymans, S., Lakdawala, N. K., Tschöpe, C., & Klingel, K. (2023). Dilated cardiomyopathy: causes, mechanisms, and current and future treatment approaches. Lancet, 402(10406), 998-1011. https://doi.org/10.1016/S0140-6736(23)01241-2
    • Kerstens, T. P., Weerts, J., van Dijk, A. P. J., Weijers, G., Knackstedt, C., Eijsvogels, T. M. H., Oxborough, D., van Empel, V. P. M., & Thijssen, D. H. J. (2023). Association of left ventricular strain-volume loop characteristics with adverse events in patients with heart failure with preserved ejection fraction. European Heart Journal Cardiovascular Imaging, 24(9), 1168-1176. https://doi.org/10.1093/ehjci/jead117
    • Raafs, A. G., Adriaans, B. P., Henkens, M. T. H. M., Verdonschot, J. A. J., Abdul Hamid, M. A., Díez, J., Knackstedt, C., van Empel, V. P. M., Brunner-La Rocca, H. P., González, A., Wildberger, J. E., Heymans, S. R. B., & Hazebroek, M. R. (2023). Biomarkers of Collagen Metabolism Are Associated with Left Ventricular Function and Prognosis in Dilated Cardiomyopathy: A Multi-Modal Study. Journal of Clinical Medicine, 12(17), Article 5695. https://doi.org/10.3390/jcm12175695
    • Meijs, C., Brugts, J. J., Lund, L. H., Linssen, G. C. M., Brunner-La Rocca, H.-P., Dahlstrom, U., Vaartjes, I., Koudstaal, S., Asselbergs, F. W., Savarese, G., & Uijl, A. (2023). Identifying distinct clinical clusters in heart failure with mildly reduced ejection fraction. International Journal of Cardiology, 386(1), 83-90. https://doi.org/10.1016/j.ijcard.2023.05.024
    • Xu, Y., Li, Z., Wang, Y., Li, C., Zhang, M., Chen, H., Chen, W., Zhong, Q., Pei, J., Chen, W., Haenen, G. R. M. M., & Moalin, M. (2023). Unraveling the Antioxidant Activity of 2R,3R-dihydroquercetin. International Journal of Molecular Sciences, 24(18), Article 14220. https://doi.org/10.3390/ijms241814220
    • Malgie, J., Clephas, P. R. D., Brunner-La Rocca, H.-P., de Boer, R. A., & Brugts, J. J. (2023). Guideline-directed medical therapy for HFrEF: sequencing strategies and barriers for life-saving drug therapy. Heart Failure Reviews, 28(5), 1221-1234. https://doi.org/10.1007/s10741-023-10325-2
    • Vos, J. L., Raafs, A. G., Henkens, M. T. H. M., Pedrizzetti, G., van Deursen, C. J., Rodwell, L., Heymans, S. R. B., & Nijveldt, R. (2023). CMR-derived left ventricular intraventricular pressure gradients identify different patterns associated with prognosis in dilated cardiomyopathy. European Heart Journal Cardiovascular Imaging, 24(9), 1231-1240. https://doi.org/10.1093/ehjci/jead083
    • Manukjan, N., Majcher, D., Leenders, P., Caiment, F., van Herwijnen, M., Smeets, H. J. J., Suidgeest, E., van der Weerd, L., Vanmierlo, T., Jansen, J. F. A., Backes, W. H. H., van Oostenbrugge, R. J. J., Staals, J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2023). Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment. Acta neuropathologica communications, 11(1), Article 128. https://doi.org/10.1186/s40478-023-01627-5
    • Habibi, Z., Abma-Kramer, J., & Brunner-La Rocca, H.-P. (2023). A case report of high-output heart failure due to arteriovenous shunt without bowel: how to address?European Heart Journal - Case Reports, 7(8), Article ytad360. https://doi.org/10.1093/ehjcr/ytad360
    • Sikking, M. A., Stroeks, S. L. V. M., Waring, O. J., Henkens, M. T. H. M., Riksen, N. P., Hoischen, A., Heymans, S. R. B., & Verdonschot, J. A. J. (2023). Clonal Hematopoiesis of Indeterminate Potential From a Heart Failure Specialist’s Point of View. Journal of the American Heart Association, 12(15), Article e030603. https://doi.org/10.1161/JAHA.123.030603
    • Mestrum, S. G. C., Vanblarcum, R., de Wit, N. C. J., Drent, R. J. M., Boonen, B. T., van Hemert, W. L. W., Hopman, A. H. N., Ramaekers, F. C. S., & Leers, M. P. G. (2023). Impact of the gating strategy for Ki-67 and Bcl-2 on the determination of proliferation and anti-apoptosis data by flow cytometry in non-malignant bone marrow aspirates and aspirates from patients with myeloid malignancies. Data in brief, 49(1), Article 109284. https://doi.org/10.1016/j.dib.2023.109284
    • Kobayashi, M., Huttin, O., Ferreira, J. P., Duarte, K., Gonzalez, A., Heymans, S., Verdonschot, J. A. J., Brunner-La Rocca, H.-P., Pellicori, P. L., Clark, A., Petutschnigg, J., Edelmann, F. G., Cleland, J., Rossignol, P., Zannad, F., Girerd, N., & HOMAGE Trial Committees and Investigators (2023). A machine learning-derived echocardiographic algorithm identifies people at risk of heart failure with distinct cardiac structure, function, and response to spironolactone: findings from the HOMAGE trial. European journal of heart failure, 25(8), 1284-1289. https://doi.org/10.1002/ejhf.2859
    • Heymans, S., & Cooper, L. T. (2023). Author Correction: Myocarditis after COVID-19 mRNA vaccination: clinical observations and potential mechanisms. Nature Reviews Cardiology, 20(8), 575-575. https://doi.org/10.1038/s41569-023-00904-z
    • Vinke, J. S. J., Gorter, A. R., Eisenga, M. F., Dam, W. A., van der Meer, P., van den Born, J., Bakker, S. J. L., Hoes, M. F., & de Borst, M. H. (2023). Iron deficiency is related to lower muscle mass in community-dwelling individuals and impairs myoblast proliferation. Journal of cachexia, sarcopenia and muscle, 14(4), 1865-1879. https://doi.org/10.1002/jcsm.13277
    • van Mourik, M. J. W., Linz, D., Verwijs, H. J. A., Bekkers, S. C. A. M., Weerts, J., Schotten, U., Rocca, H. B.-L., Lumens, J., Crijns, H. J. G. M., Weijs, B., & Knackstedt, C. (2023). Evaluating subclinical left ventricular and left atrial dysfunction in idiopathic atrial fibrillation: A speckle-tracking based strain-analysis. International Journal of Cardiology, 383(1), 159-165. https://doi.org/10.1016/j.ijcard.2023.04.024
    • Kerkhofs, D., Helgers, R., Hermes, D., Steinbusch, H. P. J., Van Essen, H., Leenders, P., Prickaerts, J., Staals, J., Biessen, E. A., Van Oostenbrugge, R. J., & Foulquier, S. (2023). Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice. Journal of Hypertension, 41(7), 1159-1167. https://doi.org/10.1097/HJH.0000000000003445
    • Rabussier, G., Bunter, I., Bouwhuis, J., Soragni, C., van Zijp, T., Ng, C. P., Domansky, K., Windt, L. J. D., Vulto, P., Murdoch, C. E., Bircsak, K. M., & Lanz, H. L. (2023). Healthy and diseased placental barrier on-a-chip models suitable for standardized studies. Acta Biomaterialia, 164(1), 363-376. https://doi.org/10.1016/j.actbio.2023.04.033
    • Aga, Y. S., Radhoe, S. P., Aydin, D., Linssen, G. C. M., Rademaker, P. C., Geerlings, P. R., van Gent, M. W. F., Aksoy, I., Oosterom, L., Brunner-La Rocca, H. P. B. L., van Dalen, B. M., & Brugts, J. J. (2023). Heart failure treatment in patients with and without obesity with an ejection fraction below 50%. European Journal of Clinical Investigation, 53(7), Article e13976. https://doi.org/10.1111/eci.13976
    • Brugts, J. J., Radhoe, S. P., Clephas, P. R. D., Aydin, D., van Gent, M. W. F., Szymanski, M. K., Rienstra, M., van den Heuvel, M. H., da Fonseca, C. A., Linssen, G. C. M., Borleffs, C. J. W., Boersma, E., Asselbergs, F. W., Mosterd, A., Brunner-La Rocca, H. P., de Boer, R. A., Emans, M. E., Beeres, S. L. M. A., Heerebeek, L., ... MONITOR-HF investigators (2023). Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial. Lancet, 401(10394), 2113-2123. https://doi.org/10.1016/S0140-6736(23)00923-6
    • Juni, R. P., Kocken, J. M. M., Abreu, R. C., Ottaviani, L., Davalan, T., Duygu, B., Poels, E. M., Vasilevich, A., Hegenbarth, J. C., Appari, M., Bitsch, N., Olieslagers, S., Schrijvers, D. M., Stoll, M., Heineke, J., de Boer, J., de Windt, L. J., & da Costa, P. A. (2023). MicroRNA-216a is essential for cardiac angiogenesis. Molecular Therapy, 31(6), 1807-1828. https://doi.org/10.1016/j.ymthe.2023.04.007
    • ter Bekke, R. M. A., de Schouwer, K., Conti, S., Claes, G. R. F., Vanoevelen, J., Gommers, S., Helderman-van den Enden, A. T. J. M., & Brunner-LaRocca, H.-P. (2023). Juvenile-onset multifocal atrial arrhythmias, atrial standstill and compound heterozygosity of genetic variants in TAF1A: sentinel event for evolving dilated cardiomyopathy-a case report. European Heart Journal - Case Reports, 7(6), Article ytad255. https://doi.org/10.1093/ehjcr/ytad255
    • Sikking, M. A., Stroeks, S. L. V. M., Henkens, M. T. H. M., Venner, M. F. G. H. M., Li, X., Heymans, S. R. B., Hazebroek, M. R., & Verdonschot, J. A. J. (2023). Cardiac Inflammation in Adult-Onset Genetic Dilated Cardiomyopathy. Journal of Clinical Medicine, 12(12), Article 3937. https://doi.org/10.3390/jcm12123937
    • Steiner, B., Neumann, A., Pelz, Y., Ski, C. F., Hill, L., Thompson, D. R., Fitzsimons, D., Dixon, L. J., Brandts, J., Verket, M., Schuett, K., Eurlings, C. G. M. J., Boyne, J. J. J., Gingele, A. J., De Maesschalck, L., Murphy, M., da Luz, E. F., Barrett, M., Windle, K., ... PASSION-HF consortium (2023). Challenges in heart failure care in four European countries: a comparative study. European Journal of Public Health, 33(3), 448-454. https://doi.org/10.1093/eurpub/ckad059
    • Linders, A. N., Dias, I. B., Ovchinnikova, E. S., Vermeer, M. C. S. C., Hoes, M. F., Mavrogenis, G. M., Deiman, F. E., Gomez, K. F. A., Bliley, J. M., Nehme, J., Vink, A., Gietema, J., de Boer, R. A., Westenbrink, D., Sillje, H. H. W., Hilfiker-Kleiner, D., van Laake, L. W., Feinberg, A. W., Demaria, M., ... van der Meer, P. (2023). Evaluation of Senescence and Its Prevention in Doxorubicin-Induced Cardiotoxicity Using Dynamic Engineered Heart Tissues. JACC: CardioOncology, 5(3), 298-315. https://doi.org/10.1016/j.jaccao.2023.03.012
    • Vroemen, W. H. M., van Beers, J. J. B. C., Frissen, J., & de Wit, N. C. J. (2023). Hypo-osmolality and its effect on erythrocyte parameters. International Journal of Laboratory Hematology, 45(3), e93-e94. https://doi.org/10.1111/ijlh.14022
    • Vermeer, M. C. S. C., Arevalo Gomez, K. F., Hoes, M. F., Tromp, J., Verdonschot, J. A. J., Henkens, M. T. H. M., Silljé, H. H. W., Bolling, M. C., & van der Meer, P. (2023). Clinical Outcome in KLHL24 Cardiomyopathy. Circulation: Genomic and Precision Medicine, 16(4), 401-403. https://doi.org/10.1161/CIRCGEN.122.003998
    • Kerstens, T. P., Weerts, J., van Dijk, A. P. J., Weijers, G., Knackstedt, C., Eijsvogels, T. M. H., Oxborough, D., van Empel, V. P. M., & Thijssen, D. H. J. (2023). Left ventricular strain-volume loops and diastolic dysfunction in suspected heart failure with preserved ejection fraction. International Journal of Cardiology, 378(1), 144-150. https://doi.org/10.1016/j.ijcard.2023.01.084
    • Girerd, N., Levy, D., Duarte, K., Ferreira, J. P., Ballantyne, C., Collier, T., Pizard, A., Björkman, J., Butler, J., Clark, A., Cleland, J. G., Delles, C., Diez, J., González, A., Hazebroek, M., Ho, J., Huby, A. C., Hwang, S. J., Latini, R., ... Zannad, F. (2023). Protein Biomarkers of New-Onset Heart Failure: Insights From the Heart Omics and Ageing Cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study. Circulation-Heart Failure, 16(5), 426-441. Article e009694. https://doi.org/10.1161/CIRCHEARTFAILURE.122.009694
    • Knackstedt, C., Schummers, G., Schroder, J., Marx, N., Lumens, J., Sanders-van Wijk, S., Ramaekers, B., Becker, M., van Empel, V., Brunner-La Rocca, H. P., & PsychEcho study group (2023). A graphical analysis of aspects contributing to the spreading of measurements of left ventricular function. International Journal of Cardiovascular Imaging, 39(5), 915-927. https://doi.org/10.1007/s10554-023-02796-z
    • Starmans, N. L., Wolters, F. J., Leeuwis, A. E., Bron, E. E., La Rocca, H. P. B., Staals, J., Biessels, G. J., & Kappelle, L. J. (2023). Twenty-four hour blood pressure variability and the prevalence and the progression of cerebral white matter hyperintensities. Journal of Cerebral Blood Flow and Metabolism, 43(5), 801-811. https://doi.org/10.1177/0271678X221149937
    • Verdonschot, J. A. J., Wang, P., Derks, K. W. J., Adriaens, M. E., Stroeks, S. L. V. M., Henkens, M. T. H. M., Raafs, A. G., Sikking, M., de Koning, B., van den Wijngaard, A., Krapels, I. P. C., Nabben, M., Brunner, H. G., & Heymans, S. R. B. (2023). Clustering of Cardiac Transcriptome Profiles Reveals Unique Subgroups of Dilated Cardiomyopathy Patients. JACC: Basic to Translational Science, 8(4), 406-418. https://doi.org/10.1016/j.jacbts.2022.10.010
    • Haenen, G. R. M. M. (2023). Past, Present and Future of the Section "Molecular Toxicology". International Journal of Molecular Sciences, 24(7), Article 6667. https://doi.org/10.3390/ijms24076667
    • Stroeks, S. L. V. M., Lunde, I. G. G., Hellebrekers, D. M. E. I., Claes, G. R. F., Wakimoto, H., Gorham, J., Krapels, I. P. C., Vanhoutte, E. K. K., van den Wijngaard, A., Henkens, M. T. H. M., Raafs, A. G. G., Sikking, M. A. A., Broers, J. L. V., Nabben, M., Jones, E. A. V., Heymans, S. R. B., Brunner, H. G. G., & Verdonschot, J. A. J. (2023). Prevalence and Clinical Consequences of Multiple Pathogenic Variants in Dilated Cardiomyopathy. Circulation: Genomic and Precision Medicine, 16(2), Article e003788. https://doi.org/10.1161/CIRCGEN.122.003788
    • Clephas, P. R. D., Radhoe, S. P., Linssen, G. C. M., Langerveld, J., Plomp, J., Smits, J. P. P., Nagelsmit, M. J., Rocca, H. P. B. L., & Brugts, J. J. (2023). Serum potassium level and mineralocorticoid receptor antagonist dose in a large cohort of chronic heart failure patients. Esc heart failure, 10(2), 1481-1487. https://doi.org/10.1002/ehf2.14285
    • Donker, E. M., Pandit, R., Poleij, M. C. S., Brinkman, D. J., van Agtmael, M. A., van Rosse, F., Dumont, G., Kramers, C., Atiqi, R., Richir, M. C., van Smeden, J., Hessel, M. H. M., Janssen, B. J., Knol, W., Tichelaar, J., & Pharmacotherapy Education working group of the Dutch Society for Clinical Pharmacology & Biopharmacy and its affiliated Dutch Network of Clinical Pharmacology Teachers (2023). The Dutch list of essential drugs for undergraduate medical education: A modified Delphi study. British Journal of Clinical Pharmacology, 89(4), 1431-1451. https://doi.org/10.1111/bcp.15606
    • Soragni, C., Vergroesen, T., Hettema, N., Rabussier, G., Lanz, H. L., Trietsch, S. J., de Windt, L. J., & Ng, C. P. (2023). Quantify permeability using on-a-chip models in high-throughput applications. STAR protocols, 4(1), Article 102051. https://doi.org/10.1016/j.xpro.2023.102051
    • Ferreira, J. P., Cleland, J. G. F., Girerd, N., Pellicori, P., Hazebroek, M. R., Verdonschot, J., Collier, T. J., Petutschnigg, J., Clark, A. L., Staessen, J. A., Heymans, S., Rossignol, P., & Zannad, F. (2023). Effect of Spironolactone on QRS Duration in Patients at Risk for Heart Failure (from the HOMAGE Trial). American Journal of Cardiology, 191(1), 39-42. https://doi.org/10.1016/j.amjcard.2022.12.016
    • Robinson, E. L., Ameri, P., Delrue, L., Vanderheyden, M., Bartunek, J., Altieri, P., Heymans, S., & Heggermont, W. A. (2023). Differential expression of epigenetic modifiers in early and late cardiotoxic heart failure reveals DNA methylation as a key regulator of cardiotoxicity. Frontiers in Cardiovascular Medicine, 10(1), Article 884174. https://doi.org/10.3389/fcvm.2023.884174
    • Radhoe, S. P., Clephas, P. R. D., Linssen, G. C. M., Oortman, R. M., Smeele, F. J., Van Drimmelen, A. A., Schaafsma, H. J., Westendorp, P. H., Rocca, H. P. B. L., & Brugts, J. J. (2023). Phenotypic patient profiling for improved implementation of guideline-directed medical therapy: An exploratory analysis in a large real-world chronic heart failure cohort. Frontiers in Pharmacology, 14(1), Article 1081579. https://doi.org/10.3389/fphar.2023.1081579
    • de Boer, M., Hekkert, M. T., Chang, J., van Thiel, B. S., Martens, L., Bos, M. M., de Kleijnen, M. G. J., Ridwan, Y., Octavia, Y., van Deel, E. D., Blonden, L. A., Brandt, R. M. C., Barnhoorn, S., Bautista-Nino, P. K., Krabbendam-Peters, I., Wolswinkel, R., Arshi, B., Ghanbari, M., Kupatt, C., ... Duncker, D. J. (2023). DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice. Aging Cell, 22(3), Article e13768. https://doi.org/10.1111/acel.13768
    • Sanchez-Aguilera, P., Lopez-Crisosto, C., Norambuena-Soto, I., Penannen, C., Zhu, J. M., Bomer, N., Hoes, M. F., van der Meer, P., Chiong, M., Westenbrink, B. D., & Lavandero, S. (2023). IGF-1 boosts mitochondrial function by a Ca2+ uptake-dependent mechanism in cultured human and rat cardiomyocytes. Frontiers in physiology, 14(1), Article 1106662. https://doi.org/10.3389/fphys.2023.1106662
    • Gyöngyösi, M., Alcaide, P., Asselbergs, F. W., Brundel, B. J. J. M., Camici, G. G., da Costa Martins, P., Ferdinandy, P., Fontana, M., Girao, H., Gnecchi, M., Gollmann-Tepeköylü, C., Kleinbongard, P., Krieg, T., Madonna, R., Paillard, M., Pantazis, A., Perrino, C., Pesce, M., Schiattarella, G. G., ... Davidson, S. M. (2023). Long COVID and the cardiovascular system - elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: a joint Scientific Statement of the ESC Working Groups on Cellular Biology of the Heart and Myocardial and Pericardial Diseases. Cardiovascular Research, 119(2), 336-356. Article cvac115. https://doi.org/10.1093/cvr/cvac115
    • Ferreira, J. P., Cleland, J. G. F., Girerd, N., Pellicori, P., Hazebroek, M. R., Verdonschot, J., Collier, T. J., Petutschnigg, J., Clark, A. L., Staessen, J. A., Heymans, S., Zannad, F., & Rossignol, P. (2023). Early and late renal function changes with spironolactone in patients at risk of developing heart failure: findings from the HOMAGE trial. Clinical research in cardiology, 112(2), 330-332. https://doi.org/10.1007/s00392-022-02116-w