• 2020
    • Verdonschot, J. A. J., Derks, K. W. J., Hazebroek, M. R., Wang, P., Robinson, E. L., Adriaens, M. E., Krapels, I. P. C., van den Wijngaard, A., Brunner, H. G., & Heymans, S. R. B. (2020). Distinct Cardiac Transcriptomic Clustering in Titin and Lamin A/C-Associated Dilated Cardiomyopathy Patients. Circulation, 142(12), 1230-1232. https://doi.org/10.1161/circulationaha.119.045118
    • Olivotto, I., Oreziak, A., Barriales-Villa, R., Abraham, T. P., Masri, A., Garcia-Pavia, P., Saberi, S., Lakdawala, N. K., Wheeler, M. T., Owens, A., Kubanek, M., Wojakowski, W., Jensen, M. K., Gimeno-Blanes, J., Afshar, K., Myers, J., Hegde, S. M., Solomon, S. D., Sehnert, A. J., ... Brunner-La Rocca, H. P. (2020). Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet, 396(10253), 759-769. https://doi.org/10.1016/S0140-6736(20)31792-X
    • Videira, R. F., & da Costa Martins, P. A. (2020). Non-coding RNAs in Cardiac Intercellular Communication. Frontiers in physiology, 11, Article 738. https://doi.org/10.3389/fphys.2020.00738
    • Tocchetti, C. G., Ameri, P., de Boer, R. A., D'Alessandra, Y., Russo, M., Sorriento, D., Ciccarelli, M., Kiss, B., Bertrand, L., Dawson, D., Falcao-Pires, I., Giacca, M., Hamdani, N., Linke, W. A., Mayr, M., van der Velden, J., Zacchigna, S., Ghigo, A., Hirsch, E., ... Thum, T. (2020). Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs: novel cardio-oncology insights from the joint 2019 meeting of the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart. Cardiovascular Research, 116(11), 1820-1834. https://doi.org/10.1093/cvr/cvaa222
    • Linssen, G. C. M., Veenis, J. F., Kleberger, A., Grosfeld, M. J. W., Viergever, E. P., van Dalen, B. M., de Valk-Bedijn, W., Langerveld, J., Brunner-La Rocca, H. P., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2020). Medical treatment of octogenarians with chronic heart failure: data from CHECK-HF. Clinical research in cardiology, 109(9), 1155-1164. https://doi.org/10.1007/s00392-020-01607-y
    • Bar, C., Chatterjee, S., Pires, I. F., Rodrigues, P., Sluijter, J. P. G., Boon, R. A., Nevado, R. M., Andres, V., Sansonetti, M., de Windt, L., Ciccarelli, M., Hamdani, N., Heymans, S., Videira, R. F., Tocchetti, C. G., Giacca, M., Zacchigna, S., Engelhardt, S., Dimmeler, S., ... Thum, T. (2020). Non-coding RNAs: update on mechanisms and therapeutic targets from the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart. Cardiovascular Research, 116(11), 1805-1819. https://doi.org/10.1093/cvr/cvaa195
    • Vonhogen, I. G. C., Mohseni, Z., Winkens, B., Xiao, K., Thum, T., Calore, M., Martins, P. A. D. C., de Windt, L. J., Spaanderman, M. E. A., & Ghossein-Doha, C. (2020). Circulating miR-216a as a biomarker of metabolic alterations and obesity in women. Non-Coding rna research, 5(3), 144-152. https://doi.org/10.1016/j.ncrna.2020.08.001
    • Prando, V., Bertoli, S., Favaro, G., Guescini, M., Di Mauro, V., Di Bona, A., Lo Verso, F., Soares, R., Dokshokova, L., Martins, P. D. C., Capri, M., Salvioli, S., Franceschi, C., Catalucci, D., Mongillo, M., Sandri, M., & Zaglia, T. (2020). Circulating muscle-derived MIR-206 links skeletal muscle dysfunction to cardiac autonomic denervation. Vascular Pharmacology, 132, Article 106742. https://doi.org/10.1016/j.vph.2020.106742
    • Pellicori, P., Ferreira, J. P., Mariottoni, B., Brunner-La Rocca, H.-P., Ahmed, F. Z., Verdonschot, J., Collier, T., Cuthbert, J. J., Petutschnigg, J., Mujaj, B., Girerd, N., Gonzalez, A., Clark, A. L., Cosmi, F., Staessen, J. A., Heymans, S., Latini, R., Rossignol, P., Zannad, F., & Cleland, J. G. F. (2020). Effects of spironolactone on serum markers of fibrosis in people at high risk of developing heart failure: rationale, design and baseline characteristics of a proof-of-concept, randomised, precision-medicine, prevention trial. The Heart OMics in AGing (HOMAGE) trial. European journal of heart failure, 22(9), 1711-1723. https://doi.org/10.1002/ejhf.1716
    • Henkens, M. T. H. M., Remmelzwaal, S., Robinson, E. L., van Ballegooijen, A. J., Aizpurua, A. B., Verdonschot, J. A. J., Raafs, A. G., Weerts, J., Hazebroek, M. R., Wijk, S. S., Handoko, M. L., den Ruijter, H. M., Lam, C. S. P., de Boer, R. A., Paulus, W. J., van Empel, V. P. M., Vos, R., Brunner-La Rocca, H.-P., Beulens, J. W. J., & Heymans, S. R. B. (2020). Risk of bias in studies investigating novel diagnostic biomarkers for heart failure with preserved ejection fraction. A systematic review. European journal of heart failure, 22(9), 1586-1597. https://doi.org/10.1002/ejhf.1944
    • Celutkiene, J., Pudil, R., Lopez-Fernandez, T., Grapsa, J., Nihoyannopoulos, P., Bergler-Klein, J., Cohen-Solal, A., Farmakis, D., Tocchetti, C. G., von Haehling, S., Barberis, V., Flachskampf, F. A., Ceponiene, I., Haegler-Laube, E., Suter, T., Lapinskas, T., Prasad, S., de Boer, R. A., Wechalekar, K., ... Lyon, A. R. (2020). Role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the European Society of Cardiology (ESC). European journal of heart failure, 22(9), 1504-1524. https://doi.org/10.1002/ejhf.1957
    • Seferovic, P. M., Fragasso, G., Petrie, M., Mullens, W., Ferrari, R., Thum, T., Bauersachs, J., Anker, S. D., Ray, R., Cavusoglu, Y., Polovina, M., Metra, M., Ambrosio, G., Prasad, K., Seferovic, J., Jhund, P. S., Dattilo, G., Celutkiene, J., Piepoli, M., ... Rosano, G. M. C. (2020). Sodium-glucose co-transporter 2 inhibitors in heart failure: beyond glycaemic control. A position paper of the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 22(9), 1495-1503. https://doi.org/10.1002/ejhf.1954
    • Li, Z., Moalin, M., Zhang, M., Vervoort, L., Hursel, E., Mommers, A., & Haenen, G. R. M. M. (2020). The Flow of the Redox Energy in Quercetin during Its Antioxidant Activity in Water. International journal of molecular sciences, 21(17), Article 6015. https://doi.org/10.3390/ijms21176015
    • Stienen, S., Ferreira, J. P., Kobayashi, M., Preud'homme, G., Dobre, D., Machu, J.-L., Duarte, K., Bresso, E., Devignes, M.-D., Andres, N. L., Girerd, N., Aakhus, S., Ambrosio, G., Brunner-La Rocca, H.-P., Fontes-Carvalho, R., Fraser, A. G., van Heerebeek, L., de Keulenaer, G., Marino, P., ... Rossignol, P. (2020). Sex differences in circulating proteins in heart failure with preserved ejection fraction. Biology of Sex Differences, 11(1), Article 47. https://doi.org/10.1186/s13293-020-00322-7
    • Wagner, M., Bertero, E., Nickel, A., Kohlhaas, M., Gibson, G. E., Heggermont, W., Heymans, S., & Maack, C. (2020). Selective NADH communication from α-ketoglutarate dehydrogenase to mitochondrial transhydrogenase prevents reactive oxygen species formation under reducing conditions in the heart. Basic Research in Cardiology, 115(5), Article 53. https://doi.org/10.1007/s00395-020-0815-1
    • Harjola, V. P., Parissis, J., Bauersachs, J., Brunner-La Rocca, H. P., Bueno, H., Celutkiene, J., Chioncel, O., Coats, A. J. S., Collins, S. P., de Boer, R. A., Filippatos, G., Gayat, E., Hill, L., Laine, M., Lassus, J., Lommi, J., Masip, J., Mebazaa, A., Metra, M., ... Yilmaz, M. B. (2020). Acute coronary syndromes and acute heart failure: a diagnostic dilemma and high-risk combination. A statement from the Acute Heart Failure Committee of the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 22(8), 1298-1314. https://doi.org/10.1002/ejhf.1831
    • Raafs, A. G., Linssen, G. C. M., Brugts, J. J., Erol-Yilmaz, A., Plomp, J., Smits, J. P. P., Nagelsmit, M. J., Oortman, R. M., Hoes, A. W., & Brunner-La Rocca, H. P. (2020). Contemporary use of devices in chronic heart failure in the Netherlands. Esc heart failure, 7(4), 1771-1780. https://doi.org/10.1002/ehf2.12740
    • Kerkhofs, D., van Hagen, B. T., Milanova, I. V., Schell, K. J., van Essen, H., Wijnands, E., Goossens, P., Blankesteijn, W. M., Unger, T., Prickaerts, J., Biessen, E. A., van Oostenbrugge, R. J., & Foulquier, S. (2020). Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension. Theranostics, 10(21), 9512-9527. https://doi.org/10.7150/thno.44394
    • Nagumo, S., Gallinoro, E., Candreva, A., Mizukami, T., Monizzi, G., Kodeboina, M., Verstreken, S., Dierckx, R., Heggermont, W., Bartunek, J., Goethals, M., Buytaert, D., De Bruyne, B., Sonck, J., Collet, C., & Vanderheyden, M. (2020). Vessel Fractional Flow Reserve and Graft Vasculopathy in Heart Transplant Recipients. Journal of Interventional Cardiology, 2020, Article 9835151. https://doi.org/10.1155/2020/9835151
    • Heggermont, W., Pham Anh Hong Nguyen, Lau, C.-W., & Tournoy, K. (2020). A Steep Increase in the HeartLogic Index Predicts COVID-19 Disease in an Advanced Heart Failure Patient. Case reports in cardiology, 2020, Article 8896152. https://doi.org/10.1155/2020/8896152
    • Swieringa, F., Solari, F. A., Pagel, O., Beck, F., Huang, J., Feijge, M. A. H., Jurk, K., Koerver-Keularts, I. M. L. W., Mattheij, N. J. A., Faber, J., Pohlenz, J., Russo, A., Stumpel, C. T. R. M., Schrander, D. E., Zieger, B., van Der Meijden, P. E. J., Zahedi, R. P., Sickmann, A., & Heemskerk, J. W. M. (2020). Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS. Scientific Reports, 10(1), Article 11389. https://doi.org/10.1038/s41598-020-68379-3
    • Linssen, P. B. C., Brunner-La Rocca, H.-P., Schalkwijk, C. G., Beulens, J. W. J., Elders, P. J. M., Van der Heijden, A. A., Slieker, R. C., Stehouwer, C. D. A., & Henry, R. M. A. (2020). Serum Matrix Metalloproteinases and Left Atrial Remodeling-The Hoorn Study. International journal of molecular sciences, 21(14), Article 4944. https://doi.org/10.3390/ijms21144944
    • Ferro, D., van den Brink, H., Amier, R., van Buchem, M., de Bresser, J., Bron, E., Brunner-La Rocca, H.-P., Hooghiemstra, A., Marcks, N., van Rossum, A., Biessels, G. J., & Heart-Brain Connection Consortium (2020). Cerebral cortical microinfarcts: A novel MRI marker of vascular brain injury in patients with heart failure. International Journal of Cardiology, 310, 96-102. https://doi.org/10.1016/j.ijcard.2020.04.032
    • Luiken, J. J. F. P., Nabben, M., Neumann, D., & Glatz, J. F. C. (2020). Understanding the distinct subcellular trafficking of CD36 and GLUT4 during the development of myocardial insulin resistance. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1866(7), Article 165775. https://doi.org/10.1016/j.bbadis.2020.165775
    • Summer, G., Kuhn, A. R., Munts, C., Miranda-Silva, D., Leite-Moreira, A. F., Lourenco, A. P., Heymans, S., Falcao-Pires, I., & van Bilsen, M. (2020). A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF. Journal of Molecular and Cellular Cardiology, 144, 66-75. https://doi.org/10.1016/j.yjmcc.2020.05.008
    • Santos-Faria, J., Gavina, C., Rodrigues, P., Coelho, J., Martins, P. D. C., Leite-Moreira, A., & Falcao-Pires, I. (2020). MicroRNAs and ventricular remodeling in aortic stenosis. Revista portuguesa de cardiologia, 39(7), 377-387. https://doi.org/10.1016/j.repc.2019.09.014
    • Brunner-La Rocca, H.-P., Peden, C. J., Soong, J., Holman, P. A., Bogdanovskaya, M., & Barclay, L. (2020). Reasons for readmission after hospital discharge in patients with chronic diseases-Information from an international dataset. PLOS ONE, 15(6), Article 0233457. https://doi.org/10.1371/journal.pone.0233457
    • Linssen, P. B. C., Veugen, M. G. J., Henry, R. M. A., van Der Kallen, C. J. H., Kroon, A. A., Schram, M. T., Brunner-La Rocca, H.-P., & Stehouwer, C. D. A. (2020). Associations of (pre)diabetes with right ventricular and atrial structure and function: the Maastricht Study. Cardiovascular Diabetology, 19(1), Article 88. https://doi.org/10.1186/s12933-020-01055-y
    • Veenis, J. F., Brunner-La Rocca, H. P., Linssen, G. C. M., Smeele, F. J. J., Wouters, N. T. A. E., Westendorp, P. H. M., Rademaker, P. C., Hemels, M. E. W., Rienstra, M., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2020). Atrial fibrillation in chronic heart failure patients with reduced ejection fraction: The CHECK-HF registry. International Journal of Cardiology, 308, 60-66. https://doi.org/10.1016/j.ijcard.2020.03.001
    • De Majo, F., & da Costa Martins, P. A. (2020). CircRNAs in the heart: bricks in Brunelleschi's Dome. Cardiovascular Research, 116(7), 1240-1241. https://doi.org/10.1093/cvr/cvaa020
    • Linssen, G. C. M., Veenis, J. F., Brunner-La Rocca, H. P., van Pol, P. E. J., Engelen, D. J. M., van Tooren, R. M., Koornstra-Wortel, H. J. J., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2020). Differences in guideline-recommended heart failure medication between Dutch heart failure clinics: an analysis of the CHECK-HF registry. Netherlands Heart Journal, 28(6), 334-344. https://doi.org/10.1007/s12471-020-01421-1
    • Simonavicius, J., Puronaite, R., & Brunner-La Rocca, H. P. (2020). The Reply. American Journal of Medicine, 133(6), E330-E332. https://doi.org/10.1016/j.amjmed.2019.12.011
    • Verdonschot, J. A. J., Vanhoutte, E. K., Claes, G. R. F., van den Enden, A. T. J. M. H., Hoeijmakers, J. G. J., Hellebrekers, D. M. E. I., Haan, A. D., Christiaans, I., Deprez, R. H. L., Boen, H. M., Craenenbroeck, E. M. V., Loeys, B. L., Hoedemaekers, Y. M., Marcelis, C., Kempers, M., Brusse, E., Waning, J. I., Baas, A. F., Dooijes, D., ... Brunner, H. G. (2020). A mutation update for the FLNC gene in myopathies and cardiomyopathies. Human Mutation, 41(6), 1091-1111. https://doi.org/10.1002/humu.24004
    • Manukjan, N., Ahmed, Z., Fulton, D., Blankesteijn, W. M., & Foulquier, S. (2020). A Systematic Review of WNT Signaling in Endothelial Cell Oligodendrocyte Interactions: Potential Relevance to Cerebral Small Vessel Disease. Cells, 9(6), Article 1545. https://doi.org/10.3390/cells9061545
    • Suthahar, N., Meems, L. M. G., van Veldhuisen, D. J., Walter, J. E., Gansevoort, R. T., Heymans, S., Schroen, B., van der Harst, P., Kootstra-Ros, J. E., van Empel, V., Mueller, C., Bakker, S. J. L., & de Boer, R. A. (2020). High-Sensitivity Troponin-T and Cardiovascular Outcomes in the Community: Differences Between Women and Men. Mayo Clinic Proceedings, 95(6), 1158-1168. https://doi.org/10.1016/j.mayocp.2020.01.017
    • Cuijpers, I., Simmonds, S. J., van Bilsen, M., Czarnowska, E., Miqueo, A. G., Heymans, S., Kuhn, A. R., Mulder, P., Ratajska, A., Jones, E. A., & Brakenhielm, E. (2020). Microvascular and lymphatic dysfunction in HFpEF and its associated comorbidities. Basic Research in Cardiology, 115(4), Article 39. https://doi.org/10.1007/s00395-020-0798-y
    • De Majo, F., Hegenbarth, J.-C., Ruehle, F., Baer, C., Thum, T., de Boer, M., Duncker, D. J., Schroen, B., Armand, A.-S., Stoll, M., & De Windt, L. J. (2020). Dichotomy between the transcriptomic landscape of naturally versus accelerated aged murine hearts. Scientific Reports, 10(1), Article 8136. https://doi.org/10.1038/s41598-020-65115-9
    • Sacchetto, C., Vitiello, L., de Windt, L. J., Rampazzo, A., & Calore, M. (2020). Modeling Cardiovascular Diseases with hiPSC-Derived Cardiomyocytes in 2D and 3D Cultures. International Journal of Molecular Sciences, 21(9), Article 3404. https://doi.org/10.3390/ijms21093404
    • Glatz, J. F. C., Nabben, M., Young, M. E., Schulze, P. C., Taegtmeyer, H., & Luiken, J. J. F. P. (2020). Re-balancing cellular energy substrate metabolism to mend the failing heart. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1866(5), Article 165579. https://doi.org/10.1016/j.bbadis.2019.165579
    • Veenis, J. F., Brunner-La Rocca, H. P., Linssen, G. C. M., Van Gent, M. W. F., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2020). Treatment Differences in Chronic Heart Failure Patients With Reduced Ejection Fraction According to Blood Pressure. Circulation-Heart Failure, 13(5), Article 006667. https://doi.org/10.1161/circheartfailure.119.006667
    • Cannata, A., De Angelis, G., Boscutti, A., Normand, C., Artico, J., Gentile, P., Zecchin, M., Heymans, S., Merlo, M., & Sinagra, G. (2020). Arrhythmic risk stratification in non-ischaemic dilated cardiomyopathy beyond ejection fraction. Heart, 106(9), 656-664. https://doi.org/10.1136/heartjnl-2019-315942
    • Seferovic, P. M., Piepoli, M. F., Lopatin, Y., Jankowska, E., Polovina, M., Anguita-Sanchez, M., Stoerk, S., Lainscak, M., Milicic, D., Milinkovic, I., Filippatos, G., Coats, A. J. S., Anker, S., Backs, J., Bauersachs, J., Ben Gal, T., de Boer, R. A., Doehner, W., Celutkiene, J., ... Heart Failure Association Board of the European Society of Cardiology (2020). Heart Failure Association of the European Society of Cardiology Quality of Care Centres Programme: design and accreditation document. European journal of heart failure, 22(5), 763-774. https://doi.org/10.1002/ejhf.1784
    • Heggermont, W. A., Delrue, L., Dierickx, K., Dierckx, R., Verstreken, S., Goethals, M., Bartunek, J., & Vanderheyden, M. (2020). Low MicroRNA-126 Levels in Right Ventricular Endomyocardial Biopsies Coincide With Cardiac Allograft Vasculopathy in Heart Transplant Patients. Transplantation Direct, 6(5), Article e549. https://doi.org/10.1097/TXD.0000000000000995
    • Stohr, R., Brandenburg, V. M., Heine, G. H., Maeder, M. T., Leibundgut, G., Schuh, A., Jeker, U., Pfisterer, M., Sanders-van Wijk, S., & Brunner-La Rocca, H. P. (2020). Limited role for fibroblast growth factor 23 in assessing prognosis in heart failure patients: data from the TIME-CHF trial. European journal of heart failure, 22(4), 701-709. https://doi.org/10.1002/ejhf.1749
    • Brunner-La Rocca, H. P. (2020). What do we need to better understand the role of biomarkers in heart failure?International Journal of Cardiology, 304, 93-94. https://doi.org/10.1016/j.ijcard.2020.01.018
    • Vrolijk, M. F., van Essen, H., Opperhuizen, A., Bast, A., & Janssen, B. J. (2020). Haemodynamic effects of the flavonoid quercetin in rats revisited. British Journal of Pharmacology, 177(8), 1841-1852. https://doi.org/10.1111/bph.14955
    • Vonhoegen, I. G. C., el Azzouzi, H., Olieslagers, S., Vasilevich, A., de Boer, J., Tinahones, F. J., Martins, P. A. D. C., de Windt, L. J., & Murri, M. (2020). MiR-337-3p Promotes Adipocyte Browning by Inhibiting TWIST1. Cells, 9(4), Article 1056. https://doi.org/10.3390/cells9041056
    • De Bortoli, M., Vio, R., Basso, C., Calore, M., Minervini, G., Angelini, A., Melacini, P., Vitiello, L., Vazza, G., Thiene, G., Tosatto, S., Corrado, D., Iliceto, S., Rampazzo, A., & Calore, C. (2020). Novel Missense Variant in MYL2 Gene Associated With Hypertrophic Cardiomyopathy Showing High Incidence of Restrictive Physiology. Circulation: Genomic and Precision Medicine, 13(2), Article 002824. https://doi.org/10.1161/circgen.119.002824
    • Li, Z. W., Moalin, M., Zhang, M., Vervoort, L., Mommers, A., & Haenen, G. R. M. M. (2020). Delocalization of the Unpaired Electron in the Quercetin Radical: Comparison of Experimental ESR Data with DFT Calculations. International Journal of Molecular Sciences, 21(6), Article 2033. https://doi.org/10.3390/ijms21062033
    • Aizpurua, A. B., Sanders-van Wijk, S., Brunner-La Rocca, H. P., Henkens, M., Heymans, S., Beussink-Nelson, L., Shah, S. J., & van Empel, V. P. M. (2020). Validation of the HFA-PEFF score for the diagnosis of heart failure with preserved ejection fraction. European journal of heart failure, 22(3), 413-421. https://doi.org/10.1002/ejhf.1614