Raafs, A. G., Verdonschot, J. A. J., Henkens, M. T. H. M., Adriaans, B. P., Wang, P., Derks, K., Abdul Hamid, M. A., Knackstedt, C., van Empel, V. P. M., Diez, J., Brunner-La Rocca, H.-P., Brunner, H. G., Gonzalez, A., Bekkers, S. C. A. M., Heymans, S. R. B., & Hazebroek, M. R. (2021). The combination of carboxy-terminal propeptide of procollagen type I blood levels and late gadolinium enhancement at cardiac magnetic resonance provides additional prognostic information in idiopathic dilated cardiomyopathy - A multilevel assessment of myocardial fibrosis in dilated cardiomyopathy. European journal of heart failure, 23(6), 933-944. https://doi.org/10.1002/ejhf.2201

Roblain, Q., Louis, T., Yip, C., Baudin, L., Struman, I., Caolo, V., Lambert, V., Lecomte, J., Noel, A., & Heymans, S. (2021). Intravitreal injection of anti-miRs against miR-142-3p reduces angiogenesis and microglia activation in a mouse model of laser-induced choroidal neovascularization. Aging, 13(9), 12359-12377. https://doi.org/10.18632/aging.203035

Kapsokalyvas, D., Rosas, R., Janssen, R. W. A., Vanoevelen, J. M., Nabben, M., Strauch, M., Merhof, D., & van Zandvoort, M. A. M. J. (2021). Multiview deconvolution approximation multiphoton microscopy of tissues and zebrafish larvae. Scientific Reports, 11(1), Article 10160. https://doi.org/10.1038/s41598-021-89566-w

Glatz, J. F. C., Wang, F., Nabben, M., & Luiken, J. J. F. P. (2021). CD36 as a target for metabolic modulation therapy in cardiac disease. Expert Opinion on Therapeutic Targets, 25(5), 393-400. https://doi.org/10.1080/14728222.2021.1941865

Remmelzwaal, S., Beulens, J. W. J., Elders, P. J. M., Stehouwer, C. D. A., Zhang, Z., Handoko, M. L., Appelman, Y., van Empel, V., Heymans, S. R. B., Thijs, L., Staessen, J. A., & van Ballegooijen, A. J. (2021). Sex differences in the longitudinal relationship of low-grade inflammation and echocardiographic measures in the Hoorn and FLEMENGHO Study. PLOS ONE, 16(5), Article e0251148. https://doi.org/10.1371/journal.pone.0251148

D'Souza, A., Wang, Y. W., Anderson, C., Bucchi, A., Baruscotti, M., Olieslagers, S., Mesirca, P., Johnsen, A. B., Mastitskaya, S., Ni, H. B., Zhang, Y., Black, N., Cox, C., Wegner, S., Bano-Otalora, B., Petit, C., Gill, E., Logantha, S. J. R. J., Dobrzynski, H., ... Boyett, M. R. (2021). A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate. Heart Rhythm, 18(5), 801-810. https://doi.org/10.1016/j.hrthm.2020.11.026

van Gorp, R. H., Dijkgraaf, I., Bröker, V., Bauwens, M., Leenders, P., Jennen, D., Dweck, M. R., Bucerius, J., Briedé, J. J., van Ryn, J., Brandenburg, V., Mottaghy, F., Spronk, H. M. H., Reutelingsperger, C. P., & Schurgers, L. J. (2021). Off-target effects of oral anticoagulants - vascular effects of vitamin K antagonist and non-vitamin K antagonist oral anticoagulant dabigatran etexilate. Journal of Thrombosis and Haemostasis, 19(5), 1348-1363. https://doi.org/10.1111/jth.15289

Simonavicius, J., Mikalauskas, A., & Brunner-La Rocca, H. P. (2021). Soluble CD146-an underreported novel biomarker of congestion: a comment on a review concerning congestion assessment and evaluation in acute heart failure. Heart Failure Reviews, 26(3), 731-732. https://doi.org/10.1007/s10741-020-09950-y

Sanders-van Wijk, S., Barandiaran Aizpurua, A., Brunner-La Rocca, H.-P., Henkens, M. T. H. M., Weerts, J., Knackstedt, C., Uszko-Lencer, N., Heymans, S., & van Empel, V. (2021). The HFA-PEFF and H2FPEF scores largely disagree in classifying patients with suspected heart failure with preserved ejection fraction. European journal of heart failure, 23(5), 838-840. https://doi.org/10.1002/ejhf.2019

Garcia-Pavia, P., Rapezzi, C., Adler, Y., Arad, M., Basso, C., Brucato, A., Burazor, I., Caforio, A. L. P., Damy, T., Eriksson, U., Fontana, M., Gillmore, J. D., Gonzalez-Lopez, E., Grogan, M., Heymans, S., Imazio, M., Kindermann, I., Kristen, A., Maurer, M. S., ... Linhart, A. (2021). Diagnosis and treatment of cardiac amyloidosis: a position statement of the ESC Working Group on Myocardial and Pericardial Diseases. European Heart Journal, 42(16), 1554-1568. https://doi.org/10.1093/eurheartj/ehab072

Ferreira, J. P., Verdonschot, J., Wang, P., Pizard, A., Collier, T., Ahmed, F. Z., Brunner-La-Rocca, H. P., Clark, A. L., Cosmi, F., Cuthbert, J., Diez, J., Edelmann, F., Girerd, N., Gonzalez, A., Grojean, S., Hazebroek, M., Khan, J., Latini, R., Mamas, M. A., ... HOMAGE (Heart Omics in AGEing) Consortium (2021). Proteomic and Mechanistic Analysis of Spironolactone in Patients at Risk for HF. JACC: Heart Failure, 9(4), 268-277. https://doi.org/10.1016/j.jchf.2020.11.010

Rajewsky, N., Almouzni, G., Gorski, S. A., Aerts, S., Amit, I., Bertero, M. G., Bock, C., Bredenoord, A. L., Cavalli, G., Chiocca, S., Clevers, H., De Strooper, B., Eggert, A., Ellenberg, J., Fernández, X. M., Figlerowicz, M., Gasser, S. M., Hubner, N., Kjems, J., ... LifeTime Community Working Groups (2021). Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine. Nature, 592(7852), E8-E8. https://doi.org/10.1038/s41586-021-03287-8

Wong, L., Glatz, J. F. C., Wang, S., Geraets, I. M. E., Vanherle, S., van den Wijngaard, A., Brunner, H., Luiken, J. J. F. P., & Nabben, M. (2021). Comparison of human and rodent cell models to study myocardial lipid-induced insulin resistance. Prostaglandins Leukotrienes and Essential Fatty Acids, 167, Article 102267. https://doi.org/10.1016/j.plefa.2021.102267

Garcia-Pavia, P., Rapezzi, C., Adler, Y., Arad, M., Basso, C., Brucato, A., Burazor, I., Caforio, A. L. P., Damy, T., Eriksson, U., Fontana, M., Gillmore, J. D., Gonzalez-Lopez, E., Grogan, M., Heymans, S., Imazio, M., Kindermann, I., Kristen, A. V., Maurer, M. S., ... Linhart, A. (2021). Diagnosis and treatment of cardiac amyloidosis. A position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. European journal of heart failure, 23(4), 512-526. https://doi.org/10.1002/ejhf.2140

Barandiarán Aizpurua, A., Sanders-van Wijk, S., Brunner-La Rocca, H. P., Henkens, M. T. H. M., Weerts, J., Spanjers, M. H. A., Knackstedt, C., & van Empel, V. P. M. (2021). Iron deficiency impacts prognosis but less exercise capacity in heart failure with preserved ejection fraction. Esc heart failure, 8(2), 1304-1313. https://doi.org/10.1002/ehf2.13204

Geraets, I. M. E., Coumans, W. A., Strzelecka, A., Schonleitner, P., Antoons, G., Schianchi, F., Willemars, M. M. A., Kapsokalyvas, D., Glatz, J. F. C., Luiken, J. J. F. P., & Nabben, M. (2021). Metabolic Interventions to Prevent Hypertrophy-Induced Alterations in Contractile Properties In Vitro. International journal of molecular sciences, 22(7), Article 3620. https://doi.org/10.3390/ijms22073620

Sliwa, K., van der Meer, P., Petrie, M. C., Frogoudaki, A., Johnson, M. R., Hilfiker-Kleiner, D., Hamdan, R., Jackson, A. M., Ibrahim, B., Mbakwem, A., Tschoepe, C., Regitz-Zagrosek, V., Omerovic, E., Roos-Hesselink, J., Gatzoulis, M., Tutarel, O., Price, S., Heymans, S., Coats, A. J. S., ... Bauersachs, J. (2021). Risk stratification and management of women with cardiomyopathy/heart failure planning pregnancy or presenting during/after pregnancy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy. European journal of heart failure, 23(4), 527-540. https://doi.org/10.1002/ejhf.2133

Verhaert, D. V. M., Brunner-La Rocca, H.-P., van Veldhuisen, D. J., & Vernooy, K. (2021). The bidirectional interaction between atrial fibrillation and heart failure: consequences for the management of both diseases. EP Europace, 23, II40-II45. https://doi.org/10.1093/europace/euaa368

van Stipdonk, A. M. W., Schretlen, S., Dohmen, W., Brunner-LaRocca, H. P., Knackstedt, C., & Vernooy, K. (2021). Development and implementation of a cardiac resynchronisation therapy care pathway: improved process and reduced resource use. BMJ Open Quality, 10(1), Article e001072. https://doi.org/10.1136/bmjoq-2020-001072

Coene, K. L. M., Timmer, C., Goorden, S. M. I., ten Hoedt, A. E., Kluijtmans, L. A. J., Janssen, M. C. H., Rennings, A. J. M., Prinsen, H. C. M. T., Wamelink, M. M. C., Ruijter, G. J. G., Körver-Keularts, I. M. L. W., Heiner-Fokkema, M. R., van Spronsen, F. J., Hollak, C. E., Vaz, F. M., Bosch, A. M., & Huigen, M. C. D. G. (2021). Monitoring phenylalanine concentrations in the follow-up of phenylketonuria patients: An inventory of pre-analytical and analytical variation. JIMD reports, 58(1), 70-79. https://doi.org/10.1002/jmd2.12186

Gouweleeuw, L., Wajant, H., Maier, O., Eisel, U. L. M., Blankesteijn, W. M., & Schoemaker, R. G. (2021). Effects of selective TNFR1 inhibition or TNFR2 stimulation, compared to non-selective TNF inhibition, on (neuro)inflammation and behavior after myocardial infarction in male mice. Brain Behavior and Immunity, 93, 156-171. https://doi.org/10.1016/j.bbi.2021.01.001

Colpaert, R. M. W., & Calore, M. (2021). Epigenetics and microRNAs in cardiovascular diseases. Genomics, 113(2), 540-551. https://doi.org/10.1016/j.ygeno.2020.12.042

Tschoepe, C., Ammirati, E., Bozkurt, B., Caforio, A. L. P., Cooper, L. T., Felix, S. B., Hare, J. M., Heidecker, B., Heymans, S., Huebner, N., Kelle, S., Klingel, K., Maatz, H., Parwani, A. S., Spillmann, F., Starling, R. C., Tsutsui, H., Seferovic, P., & Van Linthout, S. (2021). Myocarditis and inflammatory cardiomyopathy: current evidence and future directions. Nature Reviews Cardiology, 18(3), 169-193. https://doi.org/10.1038/s41569-020-00435-x

Sun, A., Simsek Papur, O., Dirkx, E., Wong, L., Sips, T., Wang, S., Strzelecka, A., Nabben, M., Glatz, J. F. C., Neumann, D., & Luiken, J. J. F. P. (2021). Phosphatidylinositol 4-kinase III beta mediates contraction-induced GLUT4 translocation and shows its anti-diabetic action in cardiomyocytes. Cellular and Molecular Life Sciences, 78(6), 2839-2856. https://doi.org/10.1007/s00018-020-03669-7

Dufeys, C., Daskalopoulos, E. P., Castanares-Zapatero, D., Conway, S. J., Ginion, A., Bouzin, C., Ambroise, J., Bearzatto, B., Gala, J. L., Heymans, S., Papageorgiou, A. P., Vinckier, S., Cumps, J., Balligand, J. L., Vanhaverbeke, M., Sinnaeve, P., Janssens, S., Bertrand, L., Beauloye, C., & Horman, S. (2021). AMPKα1 deletion in myofibroblasts exacerbates post-myocardial infarction fibrosis by a connexin 43 mechanism. Basic Research in Cardiology, 116(1), Article 10. https://doi.org/10.1007/s00395-021-00846-y

Packer, M., Anker, S. D., Butler, J., Filippatos, G., Ferreira, J. P., Pocock, S. J., Brunner-La Rocca, H. P., Janssens, S., Tsutsui, H., Zhang, J., Brueckmann, M., Jamal, W., Cotton, D., Iwata, T., Schnee, J., Zannad, F., & EMPEROR‐Reduced Trial Committees and Investigators (2021). Influence of neprilysin inhibition on the efficacy and safety of empagliflozin in patients with chronic heart failure and a reduced ejection fraction: the EMPEROR-Reduced trial. European Heart Journal, 42(6), 671-680. https://doi.org/10.1093/eurheartj/ehaa968

Cleland, J. G. F., Ferreira, J. P., Mariottoni, B., Pellicori, P., Cuthbert, J., Verdonschot, J. A. J., Petutschnigg, J., Ahmed, F. Z., Cosmi, F., Brunner-La Rocca, H. P., Mamas, M. A., Clark, A. L., Edelmann, F., Pieske, B., Khan, J., McDonald, K., Rouet, P., Staessen, J. A., Mujaj, B., ... HOMAGE Trial Committees and Investigators (2021). The effect of spironolactone on cardiovascular function and markers of fibrosis in people at increased risk of developing heart failure: the heart 'OMics' in AGEing (HOMAGE) randomized clinical trial. European Heart Journal, 42(6), 684-696. https://doi.org/10.1093/eurheartj/ehaa758

Ski, C. F., Zippel-Schultz, B., De Maesschalck, L., Hoedemakers, T., Schutt, K., Thompson, D. R., & Brunner La-Rocca, H. P. (2021). COVID-19 shapes the future for management of patients with chronic cardiac conditions. Digital health, 7, Article 2055207621991711. https://doi.org/10.1177/2055207621991711

Daskalopoulos, E. P., & Blankesteijn, W. M. (2021). Effect of Interventions in WNT Signaling on Healing of Cardiac Injury: A Systematic Review. Cells, 10(2), Article 207. https://doi.org/10.3390/cells10020207

Hazebroek, M. R., Henkens, M. T. H. M., Raafs, A. G., Verdonschot, J. A. J., Merken, J. J., Dennert, R. M., Eurlings, C., Hamid, M. A. A., Wolffs, P. F. G., Winkens, B., Brunner-La Rocca, H. P., Knackstedt, C., van Paassen, P., van Empel, V. P. M., & Heymans, S. R. B. (2021). Intravenous immunoglobulin therapy in adult patients with idiopathic chronic cardiomyopathy and cardiac parvovirus B19 persistence: a prospective, double-blind, randomized, placebo-controlled clinical trial. European journal of heart failure, 23(2), 302-309. https://doi.org/10.1002/ejhf.2082

Simonavicius, J., & Brunner-La Rocca, H. P. (2021). Do chronic heart failure patients receive optimal decongestive interventions in a real‐life setting? Letter regarding the article ‘Association between loop diuretic dose changes and outcomes in chronic heart failure: observations from the ESC‐EORP Heart Failure Long‐Term Registry’. European journal of heart failure, 23(2), 342-342. https://doi.org/10.1002/ejhf.1839

Meier, S., Henkens, M., Heymans, S., & Robinson, E. L. (2021). Unlocking the Value of White Blood Cells for Heart Failure Diagnosis. Journal of Cardiovascular Translational Research, 14(1), 53-62. https://doi.org/10.1007/s12265-020-10007-6

Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Kaminski, I., Geomini, I., Lemmens, T., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2021). Hypoxia-induced mitochondrial abnormalities in cells of the placenta. PLOS ONE, 16(1), Article 0245155. https://doi.org/10.1371/journal.pone.0245155

Verdonschot, J. A. J., Merlo, M., Dominguez, F., Wang, P., Henkens, M. T. H. M., Adriaens, M. E., Hazebroek, M. R., Mase, M., Escobar, L. E., Cobas-Paz, R., Derks, K. W. J., van den Wijngaard, A., Krapels, I. P. C., Brunner, H. G., Sinagra, G., Garcia-Pavia, P., & Heymans, S. R. B. (2021). Phenotypic clustering of dilated cardiomyopathy patients highlights important pathophysiological differences. European Heart Journal, 42(2), 162-174. https://doi.org/10.1093/eurheartj/ehaa841

Amier, R. P., Marcks, N., Hooghiemstra, A. M., Nijveldt, R., van Buchem, M. A., de Roos, A., Biessels, G. J., Kappelle, L. J., van Oostenbrugge, R. J., Van der Geest, R. J., Bots, M. L., Greving, J. P., Niessen, W. J., van Osch, M. J. P., de Bresser, J., van de Ven, P. M., Van der Flier, W. M., Brunner-La Rocca, H. P., van Rossum, A. C., & Heart-Brain Connection Consortium (2021). Hypertensive Exposure Markers by MRI in Relation to Cerebral Small Vessel Disease and Cognitive Impairment. JACC-Cardiovascular Imaging, 14(1), 176-185. https://doi.org/10.1016/j.jcmg.2020.06.040

Cuijpers, I., Papageorgiou, A. P., Carai, P., Herwig, M., Mugge, A., Klein, T., Hamdani, N., Jones, E. A. V., & Heymans, S. (2021). Linagliptin prevents left ventricular stiffening by reducing titin cleavage and hypophosphorylation. Journal of Cellular and Molecular Medicine, 25(2), 729-741. https://doi.org/10.1111/jcmm.16122

Zacchigna, S., Paldino, A., Falcao-Pires, I., Daskalopoulos, E. P., Dal Ferro, M., Vodret, S., Lesizza, P., Cannata, A., Miranda-Silva, D., Lourenco, A. P., Pinamonti, B., Sinagra, G., Weinberger, F., Eschenhagen, T., Carrier, L., Kehat, I., Tocchetti, C. G., Russo, M., Ghigo, A., ... Working Group on Myocardial Function of the European Society of Cardiology (2021). Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function. Cardiovascular Research, 117(1), 43-59. https://doi.org/10.1093/cvr/cvaa110

Jaarsma, T., Hill, L., Bayes-Genis, A., Brunner-La Rocca, H.-P., Castiello, T., Celutkiene, J., Marques-Sule, E., Plymen, C. M., Piper, S. E., Riegel, B., Rutten, F. H., Ben Gal, T., Bauersachs, J., Coats, A. J. S., Chioncel, O., Lopatin, Y., Lund, L. H., Lainscak, M., Moura, B., ... Stromberg, A. (2021). Self-care of heart failure patients: practical management recommendations from the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 23(1), 157-174. https://doi.org/10.1002/ejhf.2008

Zippel-Schultz, B., Palant, A., Eurlings, C., Ski, C. F., Hill, L., Thompson, D. R., Fitzsimons, D., Dixon, L. J., Brandts, J., Schuett, K. A., de Maesschalck, L., Barrett, M., da Luz, E. F., Hoedemakers, T., Helms, T. M., Brunner-La Rocca, H. P., & PASSION-HF consortium (2021). Determinants of acceptance of patients with heart failure and their informal caregivers regarding an interactive decision-making system: a qualitative study. BMJ Open, 11(6), Article e046160. https://doi.org/10.1136/bmjopen-2020-046160

Schianchi, F., Glatz, J. F. C., Navarro Gascon, A., Nabben, M., Neumann, D., & Luiken, J. J. F. P. (2020). Putative Role of Protein Palmitoylation in Cardiac Lipid-Induced Insulin Resistance. International journal of molecular sciences, 21(24), Article 9438. https://doi.org/10.3390/ijms21249438

Anker, S. D., Butler, J., Filippatos, G., Khan, M. S., Ferreira, J. P., Bocchi, E., Bohm, M., Brunner-La Rocca, H. P., Choi, D. J., Chopra, V., Chuquiure, E., Giannetti, N., Gomez-Mesa, J. E., Janssens, S., Januzzi, J. L., Gonzalez-Juanatey, J. R., Merkely, B., Nicholls, S. J., Perrone, S. V., ... EMPEROR-Preserved Trial Committees and Investigators (2020). Baseline characteristics of patients with heart failure with preserved ejection fraction in the EMPEROR-Preserved trial. European journal of heart failure, 22(12), 2383-2392. https://doi.org/10.1002/ejhf.2064

de Boer, R. A., Hulot, J. S., Tocchetti, C. G., Aboumsallem, J. P., Ameri, P., Anker, S. D., Bauersachs, J., Bertero, E., Coats, A. J. S., Celutkiene, J., Chioncel, O., Dodion, P., Eschenhagen, T., Farmakis, D., Bayes-Genis, A., Jager, D., Jankowska, E. A., Kitsis, R. N., Konety, S. H., ... Backs, J. (2020). Common mechanistic pathways in cancer and heart failure. A scientific roadmap on behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). European journal of heart failure, 22(12), 2272-2289. https://doi.org/10.1002/ejhf.2029

Robinson, E. L., Azodi, M., Heymans, S., & Heggermont, W. (2020). Anthracycline-Related Heart Failure: Certain Knowledge and Open Questions : Where Do we Stand with Chemotherapyinduced Cardiotoxicity?Current Heart Failure Reports, 17(6), 357-364. https://doi.org/10.1007/s11897-020-00489-5

Janssen, D. J. A., Ament, S. M. C., Boyne, J., Schols, J. M. G. A., Brunner-La Rocca, H.-P., Maessen, J. M. C., & van den Beuken-van Everdingen, M. H. J. (2020). Characteristics for a tool for timely identification of palliative needs in heart failure: The views of Dutch patients, their families and healthcare professionals. European Journal of Cardiovascular Nursing, 19(8), 711-720. Article 1474515120918962. https://doi.org/10.1177/1474515120918962

Kocken, J. M. M., & da Costa Martins, P. A. (2020). Epigenetic Regulation of Pulmonary Arterial Hypertension-Induced Vascular and Right Ventricular Remodeling: New Opportunities?International journal of molecular sciences, 21(23), Article 8901. https://doi.org/10.3390/ijms21238901

Videira, R. F., Martins, P. A. D. C., & Falcao-Pires, I. (2020). Non-Coding RNAs as Blood-Based Biomarkers in Cardiovascular Disease. International journal of molecular sciences, 21(23), Article 9285. https://doi.org/10.3390/ijms21239285

Vangrieken, P., Remels, A. H., Al-Nasiry, S., Bast, A., Janssen, G. M. J., von Rango, U., Vroomans, D., Pinckers, Y. C. W., van Schooten, F. J., & Schiffers, P. M. H. (2020). Placental hypoxia-induced alterations in vascular function, morphology, and endothelial barrier integrity. Hypertension Research, 43(12), 1361-1374. https://doi.org/10.1038/s41440-020-0528-8

Lanfear, D. E., Luzum, J. A., She, R., Gui, H., Donahue, M. P., O'Connor, C. M., Adams, K. F., Sanders-van Wijk, S., Zeld, N., Maeder, M. T., Sabbah, H. N., Kraus, W. E., Brunner-La Rocca, H.-P., Li, J., & Williams, L. K. (2020). Polygenic Score for β-Blocker Survival Benefit in European Ancestry Patients With Reduced Ejection Fraction Heart Failure. Circulation-Heart Failure, 13(12), Article 007012. https://doi.org/10.1161/circheartfailure.119.007012

Vernooy, K., & Brunner-La Rocca, H.-P. (2020). The importance of electrocardiographic follow-up in heart failure. European journal of heart failure, 22(12), 2380-2382. https://doi.org/10.1002/ejhf.2054