• 2017
    • Liu, Y., Steinbusch, L. K. M., Nabben, M., Kapsokalyvas, D., van Zandvoort, M., Schonleitner, P., Antoons, G., Simons, P. J., Coumans, W. A., Geomini, A., Chanda, D., Glatz, J. F. C., Neumann, D., & Luiken, J. J. F. P. (2017). Palmitate-Induced Vacuolar-Type H(+)-ATPase Inhibition Feeds Forward Into Insulin Resistance and Contractile Dysfunction. Diabetes, 66(6), 1521-1534. https://doi.org/10.2337/db16-0727
    • Robaeys, W., Bektas, S., Boyne, J., van Empel, V., Uszko-Lencer, N., Knackstedt, C., & Brunner-La Rocca, H. P. (2017). Pulmonary and right ventricular dysfunction are frequently present in heart failure irrespective of left ventricular ejection fraction. Heart Asia, 9(2), 1-8. https://doi.org/10.1136/heartasia-2017-010914
    • Nabben, M., Schmitz, J. P. J., Ciapaite, J., le Clercq, C. M. P., van Riel, N. A., Haak, H. R., Nicolay, K., de Coo, I. F. M., Smeets, H., Praet, S. F., van Loon, L. J., & Prompers, J. J. (2017). Dietary nitrate does not reduce oxygen cost of exercise or improve muscle mitochondrial function in patients with mitochondrial myopathy. American Journal of Physiology-regulatory Integrative and Comparative Physiology, 312(5), R689-R701. https://doi.org/10.1152/ajpregu.00264.2016
    • Bektas, S., Franssen, F. M. E., van Empel, V., Uszko-Lencer, N., Boyne, J., Knackstedt, C., & Brunner-La Rocca, H. P. (2017). Impact of airflow limitation in chronic heart failure. Netherlands Heart Journal, 25(5), 335-342. https://doi.org/10.1007/s12471-017-0965-4
    • Uitterdijk, A., Springeling, T., Hermans, K. C. M., Merkus, D., de Beer, V. J., Gorsse-Bakker, C., Mokelke, E., Daskalopoulos, E. P., Wielopolski, P. A., Cleutjens, J. P. M., Blankesteijn, W. M., Prinzen, F. W., van der Giessen, W. J., van Geuns, R.-J. M., & Duncker, D. J. (2017). Intermittent pacing therapy favorably modulates infarct remodeling. Basic Research in Cardiology, 112(3), Article 28. https://doi.org/10.1007/s00395-017-0616-3
    • Meani, P., Gelsomino, S., Natour, E., Johnson, D. M., Rocca, H.-P. B. L., Pappalardo, F., Bidar, E., Makhoul, M., Raffa, G., Heuts, S., Lozekoot, P., Kats, S., Sluijpers, N., Schreurs, R., Delnoij, T., Montalti, A., Sels, J. W., van de Poll, M., Roekaerts, P., ... Lorusso, R. (2017). Modalities and Effects of Left Ventricle Unloading on Extracorporeal Life support: a Review of the Current Literature. European journal of heart failure, 19 Suppl 2, 84-91. https://doi.org/10.1002/ejhf.850
    • Davarzani, N., van Wijk, S., Karel, J., Maeder, M. T., Leibundgut, G., Gutmann, M., Pfisterer, M. E., Rickenbacher, P., Peeters, R., & Brunner-La Rocca, H. (2017). N-Terminal Pro-B-Type Natriuretic Peptide-Guided Therapy in Chronic Heart Failure Reduces Repeated Hospitalizations-Results From TIME-CHF. Journal of Cardiac Failure, 23(5), 382-389. https://doi.org/10.1016/j.cardfail.2017.02.001
    • Sthijns, M. M. J. P. E., Schiffers, P. M., Janssen, G. M., Lemmens, K. J. A., Ides, B., Vangrieken, P., Bouwman, F. G., Mariman, E. C., Pader, I., Arner, E. S. J., Johansson, K., Bast, A., & Haenen, G. R. M. M. (2017). Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress. Biochimica et Biophysica Acta-general Subjects, 1861(5), 1177-1189. https://doi.org/10.1016/j.bbagen.2017.03.004
    • Veugen, M. G. J., Henry, R. M. A., van Sloten, T. T., Hermeling, E., Brunner-La Rocca, H.-P., Schram, M. T., Dagnelie, P. C., Schalkwijk, C. G., Kroon, A. A., Stehouwer, C. D. A., & Reesink, K. D. (2017). The systolic-diastolic difference in carotid stiffness is increased in type 2 diabetes: The Maastricht Study. Journal of Hypertension, 35(5), 1052-1060. https://doi.org/10.1097/HJH.0000000000001298
    • Chanda, D., Oligschlaeger, Y., Geraets, I., Liu, Y., Zhu, X., Li, J., Nabben, M., Coumans, W., Luiken, J. J. F. P., Glatz, J. F. C., & Neumann, D. (2017). 2-Arachidonoylglycerol ameliorates inflammatory stress-induced insulin resistance in cardiomyocytes. Journal of Biological Chemistry, 292(17), 7105-7114. https://doi.org/10.1074/jbc.M116.767384
    • van Empel, V., Knackstedt, C., van Paassen, P., & Brunner-La Rocca, H.-P. (2017). Just air good enough in pulmonary hypertension?European Heart Journal, 38(15), 1169-1171. https://doi.org/10.1093/eurheartj/ehx117
    • Woudstra, L., Biesbroek, P. S., Emmens, R. W., Heymans, S., Juffermans, L. J., van Rossum, A. C., Niessen, H. W. M., & Krijnen, P. A. J. (2017). Lymphocytic myocarditis occurs with myocardial infarction and coincides with increased inflammation, hemorrhage and instability in coronary artery atherosclerotic plaques. International Journal of Cardiology, 232, 53-62. https://doi.org/10.1016/j.ijcard.2017.01.052
    • Rienks, M., Papageorgiou, A., Wouters, K., Verhesen, W., van Leeuwen, R., Carai, P., Summer, G., Westermann, D., & Heymans, S. (2017). A novel 72-kDa leukocyte-derived osteoglycin enhances the activation of toll-like receptor 4 and exacerbates cardiac inflammation during viral myocarditis. Cellular and Molecular Life Sciences, 74(8), 1511-1525. https://doi.org/10.1007/s00018-016-2423-7
    • Woudstra, L., Biesbroek, P. S., Emmens, R. W., Heymans, S., Juffermans, L. J., van der Wal, A. C., van Rossum, A. C., Niessen, H. W. M., & Krijnen, P. A. J. (2017). CD45 is a more sensitive marker than CD3 to diagnose lymphocytic myocarditis in the endomyocardiurn. Human Pathology, 62, 83-90. https://doi.org/10.1016/j.humpath.2016.11.006
    • Skobel, E., Knackstedt, C., Martinez-Romero, A., Salvi, D., Vera-Munoz, C., Napp, A., Luprano, J., Bover, R., Gloeggler, S., Bjarnason-Wehrens, B., Marx, N., Rigby, A., & Cleland, J. (2017). Internet-based training of coronary artery patients: the Heart Cycle Trial. Heart and Vessels, 32(4), 408-418. https://doi.org/10.1007/s00380-016-0897-8
    • Aimo, A., Vergaro, G., Ripoli, A., Bayes-Genis, A., Figal, D. A. P., de Boer, R. A., Lassus, J., Mebazaa, A., Gayat, E., Breidthardt, T., Sabti, Z., Mueller, C., Brunner-La Rocca, H.-P., Tang, W. H. W., Grodin, J. L., Zhang, Y., Bettencourt, P., Maisel, A. S., Passino, C., ... Emdin, M. (2017). Meta-Analysis of Soluble Suppression of Tumorigenicity-2 and Prognosis in Acute Heart Failure. JACC: Heart Failure, 5(4), 287-296. https://doi.org/10.1016/j.jchf.2016.12.016
    • Palau-Caballero, G., Walmsley, J., Van Empel, V., Lumens, J., & Delhaas, T. (2017). Why septal motion is a marker of right ventricular failure in pulmonary arterial hypertension: mechanistic analysis using a computer model. American Journal of Physiology-heart and Circulatory Physiology, 312(4), H691-H700. https://doi.org/10.1152/ajpheart.00596.2016
    • Kasaai, B., Caolo, V., Peacock, H. M., Lehoux, S., Gomez-Perdiguero, E., Luttun, A., & Jones, E. A. V. (2017). Erythro-myeloid progenitors can differentiate from endothelial cells and modulate embryonic vascular remodeling. Scientific Reports, 7, 43817. https://doi.org/10.1038/srep43817
    • Duygu, B., Poels, E. M., Juni, R., Bitsch, N., Ottaviani, L., Olieslagers, S., de Windt, L. J., & da Costa Martins, P. A. (2017). miR-199b-5p is a regulator of left ventricular remodeling following myocardial infarction. Non-coding RNA research, 2(1), 18-26. https://doi.org/10.1016/j.ncrna.2016.12.002
    • Smilde, B. J., Woudstra, L., Hing, G. F., Wouters, D., Zeerleder, S., Murk, J.-L., van Ham, M., Heymans, S., Juffermans, L. J. M., van Rossum, A. C., Niessen, H. W. M., Krijnen, P. A. J., & Emmens, R. W. (2017). Reply to the letter to the editor "Is colchicine really harmful in viral myocarditis?". International Journal of Cardiology, 229, 43-43. https://doi.org/10.1016/j.ijcard.2016.11.292
    • McDermott-Roe, C., Leleu, M., Rowe, G. C., Palygin, O., Bukowy, J. D., Kuo, J., Rech, M., Hermans-Beijnsberger, S., Schaefer, S., Adami, E., Creemers, E. E., Heinig, M., Schroen, B., Arany, Z., Petretto, E., & Geurts, A. M. (2017). Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function. PLOS ONE, 12(2), Article 0170458. https://doi.org/10.1371/journal.pone.0170458
    • Daamen, M. A. M. J., Brunner-la Rocca, H. .-P., Tan, F. E. S., Hamers, J. P. H., & Schols, J. M. G. A. (2017). Clinical diagnosis of heart failure in nursing home residents based on history, physical exam, BNP and ECG: Is it reliable?European Geriatric Medicine, 8(1), 59-65. https://doi.org/10.1016/j.eurger.2016.10.003
    • Uszko-Lencer, N. H. M. K., Frankenstein, L., Spruit, M. A., Maeder, M. T., Gutmann, M., Muzzarelli, S., Osswald, S., Pfisterer, M. E., Zugck, C., Brunner-La Rocca, H.-P., & Investigators, TIME.-CHF. (2017). Predicting hospitalization and mortality in patients with heart failure: The BARDICHE-index. International Journal of Cardiology, 227, 901-907. https://doi.org/10.1016/j.ijcard.2016.11.122
    • Knackstedt, C., Heymans, S., & Brunner-La Rocca, H.-P. (2017). ICD Implantation in Patients with Nonischemic Heart Failure. New England Journal of Medicine, 376(1), 91-92. https://doi.org/10.1056/NEJMc1614441
    • van Kimmenade, R. R. J., ten Cate, T. J., & Rocca, H.-P. B.-L. (2017). Worsening Renal Function in Heart Failure It Takes 2 to Tangle. Journal of the American College of Cardiology, 69(1), 70-72. https://doi.org/10.1016/j.jacc.2016.11.016
    • Momken, I., Chabowski, A., Dirkx, E., Nabben, M., Jain, S. S., McFarlan, J. T., Glatz, J. F. C., Luiken, J. J. F. P., & Bonen, A. (2017). A new leptin-mediated mechanism for stimulating fatty acid oxidation: a pivotal role for sarcolemmal FAT/CD36. Biochemical Journal, 474(1), 149-162. https://doi.org/10.1042/BCJ20160804
    • Ghossein-Doha, C., Van Neer, J., Wissink, B., Breetveld, N. M., De Windt, L. J., Van Dijk, A. P. J., Van Der Vlugt, M. J., Janssen, M. C. H., Heidema, W. M., Scholten, R. R., & Spaanderman, M. E. A. (2017). Pre-eclampsia: an important risk factor for asymptomatic heart failure. Ultrasound in Obstetrics & Gynecology, 49(1), 143-149. https://doi.org/10.1002/uog.17343
    • Breetveld, N. M., Ghossein-Doha, C., Van Kuijk, S. M. J., Van Dijk, A. P., Van Der Vlugt, M. J., Heidema, W. M., Van Neer, J., Van Empel, V., Brunner-La Rocca, H. .-P., Scholten, R. R., & Spaanderman, M. E. A. (2017). Prevalence of asymptomatic heart failure in formerly pre-eclamptic women: a cohort study. Ultrasound in Obstetrics & Gynecology, 49(1), 134-142. https://doi.org/10.1002/uog.16014
    • Hooghiemstra, A. M., Bertens, A. S., Leeuwis, A. E., Bron, E. E., Bots, M. L., Brunner-La Rocca, H.-P., de Craen, A. J. M., van der Geest, R. J., Greving, J. P., Kappelle, L. J., Niessen, W. J., van Oostenbrugge, R. J., van Osch, M. J. P., de Roos, A., van Rossum, A. C., Biessels, G. J., van Buchem, M. A., Daemen, M. J. A. P., van der Flier, W. M., & Heart-Brain Connection Consortium (2017). The Missing Link in the Pathophysiology of Vascular Cognitive Impairment: Design of the Heart-Brain Study. Cerebrovascular Diseases Extra, 7(3), 140-152. https://doi.org/10.1159/000480738
  • 2016
    • Heggermont, W. A., Papageorgiou, A.-P., Heymans, S., & van Bilsen, M. (2016). Metabolic support for the heart: complementary therapy for heart failure?European journal of heart failure, 18(12), 1420-1429. https://doi.org/10.1002/ejhf.678
    • Luiken, J. J. F. P., Chanda, D., Nabben, M., Neumann, D., & Glatz, J. F. C. (2016). Post-translational modifications of CD36 (SR-B2): Implications for regulation of myocellular fatty acid uptake. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1862(12), 2253-2258. https://doi.org/10.1016/j.bbadis.2016.09.004
    • Verdonschot, J., Hazebroek, M., Merken, J., Debing, Y., Dennert, R., Brunner-La Rocca, H., & Heymans, S. (2016). Relevance of cardiac parvovirus B19 in myocarditis and dilated cardiomyopathy: review of the literature. European journal of heart failure, 18(12), 1430-1441. https://doi.org/10.1002/ejhf.665
    • Heymans, S., Eriksson, U., Lehtonen, J., & Cooper, L. T. . J. (2016). The Quest for New Approaches in Myocarditis and Inflammatory Cardiomyopathy. Journal of the American College of Cardiology, 68(21), 2348-2364. https://doi.org/10.1016/j.jacc.2016.09.937
    • Ferreira, J. P., Girerd, N., Pellicori, P., Duarte, K., Girerd, S., Pfeffer, M. A., McMurray, J. J. V., Pitt, B., Dickstein, K., Jacobs, L., Staessen, J. A., Butler, J., Latini, R., Masson, S., Mebazaa, A., Brunner-La Rocca, H., Delles, C., Heymans, S., Sattar, N., ... Rossignol, P. (2016). Renal function estimation and Cockroft-Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: The Heart 'OMics' in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. BMC Medicine, 14(1), Article 181. https://doi.org/10.1186/s12916-016-0731-2
    • Hensgens, K., Merken, J., Hazebroek, M., & Heymans, S. R. B. (2016). Chronic Q fever leads to dilated cardiomyopathy in a 48-year-old male. International Journal of Cardiology, 222, 705-706. https://doi.org/10.1016/j.ijcard.2016.08.024
    • Choi, Y. S., de Mattos, A. B. M., Shao, D., Li, T., Nabben, M., Kim, M., Wang, W., Tian, R., & Kolwicz, S. C. . J. (2016). Preservation of myocardial fatty acid oxidation prevents diastolic dysfunction in mice subjected to angiotensin II infusion. Journal of Molecular and Cellular Cardiology, 100, 64-71. https://doi.org/10.1016/j.yjmcc.2016.09.001
    • Gupta, S. K., Foinquinos, A., Thum, S., Remke, J., Zimmer, K., Bauters, C., de Groote, P., Boon, R. A., de Windt, L. J., Preissl, S., Hein, L., Batkai, S., Pinet, F., & Thum, T. (2016). Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction. Journal of the American College of Cardiology, 68(14), 1557-1571. https://doi.org/10.1016/j.jacc.2016.07.739
    • Criel, M., Izzi, B., Vandenbriele, C., Liesenborghs, L., Van Kerckhoven, S., Lox, M., Cludts, K., Jones, E. A. V., Vanassche, T., Verhamme, P., & Hoylaerts, M. (2016). Absence of Pear1 does not affect murine platelet function in vivo. Thrombosis Research, 146, 76-83. https://doi.org/10.1016/j.thromres.2016.08.026
    • Brandenburg, V. M., Brunner-La Rocca, H., & Marx, N. (2016). Heart Failure Therapy in Patients with Diabetes The new Benefit-Risk-Assessment of Sacubitril/Valsartan. Deutsche Medizinische Wochenschrift, 141(22), 1647-1649. https://doi.org/10.1055/s-0042-000001
    • Glatz, J. F. C., Nabben, M., Heather, L. C., Bonen, A., & Luiken, J. J. F. P. (2016). Regulation of the subcellular trafficking of CD36, a major determinant of cardiac fatty acid utilization. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1861(10), 1461-1471. https://doi.org/10.1016/j.bbalip.2016.04.008
    • Summer, G., Kelder, T., Radonjic, M., van Bilsen, M., Wopereis, S., & Heymans, S. (2016). The Network Library: a framework to rapidly integrate network biology resources. Bioinformatics, 32(17), 473-478. https://doi.org/10.1093/bioinformatics/btw436
    • Smilde, B. J., Woudstra, L., Hing, G. F., Wouters, D., Zeerleder, S., Murk, J.-L., van Ham, M., Heymans, S., Juffermans, L. J. M., van Rossum, A. C., Niessen, H. W. M., Krijnen, P. A. J., & Emmens, R. W. (2016). Colchicine aggravates coxsackievirus B3 infection in mice. International Journal of Cardiology, 216, 58-65. https://doi.org/10.1016/j.ijcard.2016.04.144
    • Altara, R., Manca, M., Hessel, M. H., Gu, Y., van Vark, L. C., Akkerhuis, K. M., Staessen, J. A., Struyker Boudier, H., Booz, G. W., & Blankesteijn, M. (2016). CXCL10 Is a Circulating Inflammatory Marker in Patients with Advanced Heart Failure: a Pilot Study. Journal of Cardiovascular Translational Research, 9(4), 302-314. https://doi.org/10.1007/s12265-016-9703-3
    • Maeder, M. T., Zurek, M., Rickli, H., Tobler, D., Kiencke, S., Suter, T., Yoon, S.-I., Julius, B., Pfisterer, M. E., & Brunner-La Rocca, H. (2016). Prognostic Value of the Change in Heart Rate From the Supine to the Upright Position in Patients With Chronic Heart Failure. Journal of the American Heart Association, 5(8), Article e003524. https://doi.org/10.1161/JAHA.116.003524
    • Vurma, M., Dang, L., Brunner-La Rocca, H., Sutsch, G., Attenhofer-Jost, C. H., Duru, F., & Scharf, C. (2016). Safety and efficacy of the nMARQ catheter for paroxysmal and persistent atrial fibrillation. EP Europace, 18(8), 1164-1169. https://doi.org/10.1093/europace/euw048