• 2016
    • van Gisbergen, M. W., Cebula, M., Zhang, J., Ottosson-Wadlund, A., Dubois, L., Lambin, P., Tew, K. D., Townsend, D. M., Haenen, G. R. M. M., Drittij - Reijnders, M. J., Saneyoshi, H., Araki, M., Shishido, Y., Ito, Y., Arner, E. S. J., Abe, H., Morgenstern, R., & Johansson, K. (2016). Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells. Molecular Pharmaceutics, 13(6), 2010-2025. https://doi.org/10.1021/acs.molpharmaceut.6b00140
    • Ottaviani, L., De Windt, L. J., & da Costa Martins, P. A. (2016). Exosomes: scytales in the damaged heart. Annals of translational medicine, 4(11), Article 222. https://doi.org/10.21037/atm.2016.05.17
    • Nabben, M., & Neumann, D. (2016). GSK-3 Inhibitors: Anti-Diabetic Treatment Associated with Cardiac Risk?Cardiovascular Drugs and Therapy, 30(3), 233-235. https://doi.org/10.1007/s10557-016-6669-y
    • Gupta, S. K., Itagaki, R., Zheng, X., Batkai, S., Thum, S., Ahmad, F., Van Aelst, L. N., Sharma, A., Piccoli, M.-T., Weinberger, F., Fiedler, J., Heuser, M., Heymans, S., Falk, C. S., Foerster, R., Schrepfer, S., & Thum, T. (2016). miR-21 promotes fibrosis in an acute cardiac allograft transplantation model. Cardiovascular Research, 110(2), 215-226. https://doi.org/10.1093/cvr/cvw030
    • Vegter, E. L., van der Meer, P., de Windt, L. J., Pinto, Y. M., & Voors, A. A. (2016). MicroRNAs in heart failure: from biomarker to target for therapy. European journal of heart failure, 18(5), 457-468. https://doi.org/10.1002/ejhf.495
    • Maessen, D. E., Brouwers, O., Gaens, K. H., Wouters, K., Cleutjens, J. P., Janssen, B. J., Miyata, T., Stehouwer, C. D., & Schalkwijk, C. G. (2016). Delayed Intervention With Pyridoxamine Improves Metabolic Function and Prevents Adipose Tissue Inflammation and Insulin Resistance in High-Fat Diet-Induced Obese Mice. Diabetes, 65(4), 956-966. https://doi.org/10.2337/db15-1390
    • Sanders-van Wijk, S., Masson, S., Milani, V., Rickenbacher, P., Gorini, M., Tavazzi, L. T., Tobler, D., Rickli, H., Latini, R., & Brunner-La Rocca, H. (2016). Interaction of Galectin-3 Concentrations with the Treatment Effects of beta-Blockers and RAS Blockade in Patients with Systolic Heart Failure: A Derivation-Validation Study from TIME-CHF and GISSI-HF. Clinical Chemistry, 62(4), 605-616. https://doi.org/10.1373/clinchem.2015.246850
    • Gast, M., Schroen, B., Voigt, A., Haas, J., Kuehl, U., Lassner, D., Skurk, C., Escher, F., Wang, X., Kratzer, A., Michalik, K., Papageorgiou, A., Peters, T., Loebel, M., Wilk, S., Althof, N., Prasanth, K. V., Katus, H., Meder, B., ... Poller, W. (2016). Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity. Journal of Molecular Cell Biology, 8(2), 178-181. https://doi.org/10.1093/jmcb/mjw003
    • van Bree, B. W. J., Lenaers, E., Nabben, M., Briede, J. J., Jorgensen, J. A., Schaart, G., Schrauwen, P., Hoeks, J., & Hesselink, M. K. C. (2016). A genistein-enriched diet neither improves skeletal muscle oxidative capacity nor prevents the transition towards advanced insulin resistance in ZDF rats. Scientific Reports, 6, Article 22854. https://doi.org/10.1038/srep22854
    • Dennert, R., Streukens, B., Gommers, S., Heymans, S., & Bekkers, B. (2016). Perimyocarditis Complicated by Early Development of Constrictive Pericarditis. Canadian Journal of Cardiology, 32(3), 395.e11-395.e12. https://doi.org/10.1016/j.cjca.2015.06.004
    • Peters, T., Beijnsberger, S., Beqqali, A., Bitsch, N., Nakagawa, S., Prasanth, K. V., de Windt, L. J., van Oort, R. J., Heymans, S., & Schroen, B. (2016). Long Non-Coding RNA Malat-1 Is Dispensable during Pressure Overload-Induced Cardiac Remodeling and Failure in Mice. PLOS ONE, 11(2), Article e0150236. https://doi.org/10.1371/journal.pone.0150236
    • Viereck, J., Kumarswamy, R., Foinquinos, A., Xiao, K., Avramopoulos, P., Kunz, M., Dittrich, M., Maetzig, T., Zimmer, K., Remke, J., Just, A., Fendrich, J., Scherf, K., Bolesani, E., Schambach, A., Weidemann, F., Zweigerdt, R., de Windt, L. J., Engelhardt, S., ... Thum, T. (2016). Long noncoding RNA Chast promotes cardiac remodeling. Science Translational Medicine, 8(326), Article 326ra22. https://doi.org/10.1126/scitranslmed.aaf1475
    • Lupon, J., Sanders-van Wijk, S., Januzzi, J. L., de Antonio, M., Gaggin, H. K., Pfisterer, M., Galan, A., Shah, R., Brunner-La Rocca, H., & Bayes-Genis, A. (2016). Prediction of survival and magnitude of reverse remodeling using the ST2-R2 score in heart failure: A multicenter study. International Journal of Cardiology, 204, 242-247. https://doi.org/10.1016/j.ijcard.2015.11.163
    • Ruijters, E., Haenen, G. R., Willemsen, M., Weseler, A. R., & Bast, A. (2016). Food-Derived Bioactives Can Protect the Anti-Inflammatory Activity of Cortisol with Antioxidant-Dependent and -Independent Mechanisms. International journal of molecular sciences, 17(2), Article 239. https://doi.org/10.3390/ijms17020239
    • Kriemler, S., Radtke, T., Bürgi, F., Lambrecht, J., Zehnder, M., & Brunner-La Rocca, H. (2016). Short-term cardiorespiratory adaptation to high altitude in children compared with adults. Scandinavian Journal of Medicine & Science in Sports, 26(2), 147-155. https://doi.org/10.1111/sms.12422
    • Duygu, B., de Windt, L. J., & Da Costa Martins, P. (2016). Targeting microRNAs in heart failure. Trends in Cardiovascular Medicine, 26(2), 99-110. https://doi.org/10.1016/j.tcm.2015.05.008
    • Marsch, E., Theelen, T., Janssen, B. J., Briedé, J. J., Haenen, G. R., Senden, J., van Loon, L. J., Poeze - van Bokhoven, M., Bierau, J., Gijbels, M. J., Daemen, M. J., & Sluimer, J. (2016). The effect of prolonged dietary nitrate supplementation on atherosclerosis development. Atherosclerosis, 245, 212-221. https://doi.org/10.1016/j.atherosclerosis.2015.11.031
    • Hermans, K. C. M., Daskalopoulos, E. P., & Blankesteijn, M. (2016). The Janus face of myofibroblasts in the remodeling heart. Journal of Molecular and Cellular Cardiology, 91, 35-41. https://doi.org/10.1016/j.yjmcc.2015.11.017
    • Uitterdijk, A., Hermans, K. C. M., de Wijs-Meijler, D. P. M., Daskalopoulos, E. P., Reiss, I. K., Duncker, D. J., Blankesteijn, M., & Merkus, D. (2016). UM206, a selective Frizzled antagonist, attenuates adverse remodeling after myocardial infarction in swine. Laboratory Investigation, 96(2), 168-176. https://doi.org/10.1038/labinvest.2015.139
    • Brunner-La Rocca, H., Fleischhacker, L., Golubnitschaja, O., Heemskerk, F., Helms, T., Hoedemakers, T., Allianses, S. H., Jaarsma, T., Kinkorova, J., Ramaekers, J., Ruff, P., Schnur, I., Vanoli, E., Verdu, J., & Zippel-Schultz, B. (2016). Challenges in personalised management of chronic diseases-heart failure as prominent example to advance the care process. The EPMA Journal, 7, Article 2. https://doi.org/10.1186/s13167-016-0051-9
    • Randall, M., Haenen, G. R., Bouwman, F. G., Vliet, A. V., & Bast, A. (2016). The tobacco smoke component acrolein induces glucocorticoid resistant gene expression via inhibition of histone deacetylase. Toxicology Letters, 240(1), 43-49. https://doi.org/10.1016/j.toxlet.2015.10.009
    • Daamen, M. A. M. J., Hamers, J. P. H., Gorgels, A. P. M., Tan, F. E. S., Schols, J. M. G. A., & Brunner-La Rocca, H. (2016). Treatment of heart failure in nursing home residents. Journal of Geriatric Cardiology, 13(1), 44-50. https://doi.org/10.11909/j.issn.1671-5411.2016.01.001
    • Van Aelst, L. N. L., Summer, G., Li, S., Gupta, S. K., Heggermont, W., De Vusser, K., Carai, P., Naesens, M., Van Cleemput, J., Van de Werf, F., Vanhaecke, J., Thum, T., Waer, M., Papageorgiou, A. .-P., Schroen, B., & Heymans, S. (2016). RNA Profiling in Human and Murine Transplanted Hearts: Identification and Validation of Therapeutic Targets for Acute Cardiac and Renal Allograft Rejection. American Journal of Transplantation, 16(1), 99-110. https://doi.org/10.1111/ajt.13421
    • van der Velden - Daamen, M., Hamers, J., Brunner-La Rocca, H., & Schols, J. (2016). Hartfalen bij verpleeghuisbewoners: Een moeilijke diagnose. Nederlands Tijdschrift voor Geneeskunde, 160, Article D390. https://www.ntvg.nl/system/files/publications/d390.pdf
    • Pijls, K., Jonkers, D., Elizalde Vilalta, M., Drittij - Reijnders, M. J., Haenen, G., Bast, A., Masclee, A., & Koek, G. (2016). Is intestinal oxidative stress involved in patients with compensated liver cirrhosis?Annals of Hepatology, 15(3), 402-409. https://doi.org/10.5604/16652681.1198816
    • Begieneman, M. P. V., Emmens, R. W., Rijvers, L., Kubat, B., Paulus, W. J., Vonk, A. B. A., Rozendaal, L., Biesbroek, P. S., Wouters, D., Zeerleder, S., van Ham, M., Heymans, S., van Rossum, A. C., Niessen, H. W. M., & Krijnen, P. A. J. (2016). Ventricular myocarditis coincides with atrial myocarditis in patients. Cardiovascular Pathology, 25(2), 141-148. https://doi.org/10.1016/j.carpath.2015.12.001
  • 2015
    • Daamen, M. A. M. J., Hamers, J. P. H., Gorgels, A. P. M., Brunner-La Rocca, H. P., Tan, F. E. S., van Dieijen-Visser, M. P., & Schols, J. M. G. A. (2015). Heart failure in nursing home residents; a cross-sectional study to determine the prevalence and clinical characteristics. BMC Geriatrics, 15, Article 167. https://doi.org/10.1186/s12877-015-0166-1
    • Zuurbier, C. J., Koeman, A., & Janssen, B. J. (2015). Letter to the editor: Ketamine-only versus isoflurane effects on murine cardiac function: comparison at similar depths of anesthesia?American Journal of Physiology-heart and Circulatory Physiology, 309(12), H2160. https://doi.org/10.1152/ajpheart.00792.2015
    • van de Wier, B., Balk, J. M., Bast, A., Koek, G. H., & Haenen, G. R. (2015). Chemical characteristics for optimizing CYP2E1 inhibition. Chemico-Biological Interactions, 242, 139-144. https://doi.org/10.1016/j.cbi.2015.09.024
    • Summer, G., Kelder, T., Ono, K., Radonjic, M., Heymans, S., & Demchak, B. (2015). cyNeo4j: connecting Neo4j and Cytoscape. Bioinformatics, 31(23), 3868-3869. https://doi.org/10.1093/bioinformatics/btv460
    • Vrolijk, M. F., Opperhuizen, A., Jansen, E. H., Bast, A., & Haenen, G. R. (2015). Anticholinergic Accumulation: A Slumbering Interaction between Drugs and Food Supplements. Basic & Clinical Pharmacology & Toxicology, 117(6), 427-432. https://doi.org/10.1111/bcpt.12437
    • Philippen, L. E., Dirkx, E., Wit, J. B. M., Burggraaf, K., de Windt, L. J., & Martins, P. A. D. C. (2015). Antisense MicroRNA Therapeutics in Cardiovascular Disease: Quo Vadis?Molecular Therapy, 23(12), 1810-1818. https://doi.org/10.1038/mt.2015.133
    • Ounzain, S., Micheletti, R., Arnan, C., Plaisance, I., Cecchi, D., Schroen, B., Reverter, F., Alexanian, M., Gonzales, C., Ng, S. Y., Bussotti, G., Pezzuto, I., Notredame, C., Heymans, S., Guigo, R., Johnson, R., & Pedrazzini, T. (2015). CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis. Journal of Molecular and Cellular Cardiology, 89, 98-112. https://doi.org/10.1016/j.yjmcc.2015.09.016
    • Calore, M., De Windt, L. J., & Rampazzo, A. (2015). Genetics meets epigenetics: Genetic variants that modulate noncoding RNA in cardiovascular diseases. Journal of Molecular and Cellular Cardiology, 89, 27-34. https://doi.org/10.1016/j.yjmcc.2015.10.028
    • Philippen, L. E., Dirkx, E., da Costa-Martins, P. A., & De Windt, L. J. (2015). Non-coding RNA in control of gene regulatory programs in cardiac development and disease. Journal of Molecular and Cellular Cardiology, 89(Pt A), 51-8. https://doi.org/10.1016/j.yjmcc.2015.03.014
    • De Windt, L. J., & Thum, T. (2015). State-of-the-art on non-coding RNA bioinformatics, diagnostics and therapeutics in cardiovascular diseases: Preface to SI Non-coding RNAs in cardiovascular disease. Journal of Molecular and Cellular Cardiology, 89(Pt A), 1-2. https://doi.org/10.1016/j.yjmcc.2015.11.021
    • Brunner-La Rocca, H.-P., Eurlings, L., Richards, A. M., Januzzi, J. L., Pfisterer, M. E., Dahlstrom, U., Pinto, Y. M., Karlstrom, P., Erntell, H., Berger, R., Persson, H., O'Connor, C. M., Moertl, D., Gaggin, H. K., Frampton, C. M., Nicholls, M. G., & Troughton, R. W. (2015). Which heart failure patients profit from natriuretic peptide guided therapy? A meta-analysis from individual patient data of randomized trials. European journal of heart failure, 17(12), 1252-1261. https://doi.org/10.1002/ejhf.401
    • Rezk, B. M., van der Vijgh, W., Bast, A., & Haenen, G. (2015). Toxicity of Antioxidants. Toxicology and Forensic Medicine, 1(1), e3-e4. Article 1000TFMOJ1e002. https://doi.org/10.17140/TFMOJ-1-e002
    • Hazebroek, M. R., Kemna, M. J., Schalla, S., Sanders-van Wijk, S., Gerretsen, S. C., Dennert, R., Merken, J., Kuznetsova, T., Staessen, J. A., Brunner-La Rocca, H. P., van Paassen, P., Tervaert, J. W. C., & Heymans, S. (2015). Prevalence and prognostic relevance of cardiac involvement in ANCA-associated vasculitis: Eosinophilic granulomatosis with polyangiitis and granulomatosis with polyangiitis. International Journal of Cardiology, 199, 170-179. https://doi.org/10.1016/j.ijcard.2015.06.087
    • Corsten, M., Heggermont, W., Papageorgiou, A.-P., Deckx, S., Tijsma, A., Verhesen, W., van Leeuwen, R., Carai, P., Thibaut, H.-J., Custers, K., Summer, G., Hazebroek, M., Verheyen, F., Neyts, J., Schroen, B., & Heymans, S. (2015). The microRNA-221/-222 cluster balances the antiviral and inflammatory response in viral myocarditis. European Heart Journal, 36(42), 2909-U56. https://doi.org/10.1093/eurheartj/ehv321
    • Calore, M., & De Windt, L. J. (2015). Longing for Naiades in Heart Failure. Journal of the American College of Cardiology, 66(18), 2016-2018. https://doi.org/10.1016/j.jacc.2015.08.868
    • Grootaert, M. O. J., Martins, P. A. D. C., Bitsch, N., Pintelon, I., De Meyer, G. R. Y., Martinet, W., & Schrijvers, D. M. (2015). Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. Autophagy, 11(11), 2014-2032. https://doi.org/10.1080/15548627.2015.1096485
    • Blankesteijn, W. M. (2015). Has the search for a marker of activated fibroblasts finally come to an end?Journal of Molecular and Cellular Cardiology, 88, 120-123. https://doi.org/10.1016/j.yjmcc.2015.10.005
    • Daeichin, V., Sluimer, J. C., van der Heiden, K., Skachkov, I., Kooiman, K., Janssen, A., Janssen, B., Bosch, J. G., de Jong, N., Daemen, M. J. A. P., & van der Steen, A. F. W. (2015). Live Observation of Atherosclerotic Plaque Disruption in Apolipoprotein E-Deficient Mouse. Ultrasound International Open, 1(2), E67-71. https://doi.org/10.1055/s-0035-1565092
    • Altara, R., Gu, Y.-M., Struijker-Boudier, H. A. J., Thijs, L., Staessen, J. A., & Blankesteijn, W. M. (2015). Left Ventricular Dysfunction and CXCR3 Ligands in Hypertension: From Animal Experiments to a Population-Based Pilot Study. PLOS ONE, 10(10), Article e0141394. https://doi.org/10.1371/journal.pone.0141394
    • Lok, S. I., de Jonge, N., van Kuik, J., van Geffen, A. J. P., Huibers, M. M. H., van der Weide, P., Siera, E., Winkens, B., Doevendans, P. A., de Weger, R. A., & Da Costa Martins, P. A. (2015). MicroRNA Expression in Myocardial Tissue and Plasma of Patients with End-Stage Heart Failure during LVAD Support: Comparison of Continuous and Pulsatile Devices. PLOS ONE, 10(10), Article e0136404. https://doi.org/10.1371/journal.pone.0136404
    • d'Avenia, M., Citro, R., De Marco, M., Veronese, A., Rosati, A., Visone, R., Leptidis, S., Philippen, L., Vitale, G., Cavallo, A., Silverio, A., Prota, C., Gravina, P., De Cola, A., Carletti, E., Coppola, G., Gallo, S., Provenza, G., Bossone, E., ... De laurenzi, V. (2015). A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy. Cell Death & Disease, 6, Article e1948. https://doi.org/10.1038/cddis.2015.280
    • Kosanovic, D., Luitel, H., Dahal, B. K., Cornitescu, T., Janssen, W., Danser, A. H. J., Garrelds, I. M., De Mey, J. G. R., Fazzi, G., Schiffers, P., Iglarz, M., Fischli, W., Ghofrani, H. A., Weissmann, N., Grimminger, F., Seeger, W., Reiss, I., & Schermuly, R. T. (2015). Chymase: a multifunctional player in pulmonary hypertension associated with lung fibrosis. European Respiratory Journal, 46(4), 1084-1094. https://doi.org/10.1183/09031936.00018215
    • Salden, B. N., Montserrat, V., Troost, F. J., Bruins, M. J., Edens, L., Bartholomé, R., Haenen, G. R., Winkens, B., Koning, F., & Masclee, A. A. (2015). Letter: gluten digestion in the stomach and duodenum by Aspergillus niger-derived enzyme - things to ponder. Authors' reply. Alimentary Pharmacology & Therapeutics, 42(7), 946-947. https://doi.org/10.1111/apt.13382