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Falkenberg, K. D., Braverman, N. E., Moser, A. B., Steinberg, S. J., Klouwer, F. C. C., Schluter, A., Ruiz, M., Pujol, A., Engvall, M., Naess, K., van Spronsen, F., Korver-Keularts, I., Rubio-Gozalbo, M. E., Ferdinandusse, S., Wanders, R. J. A., & Waterham, H. R. (2017). Allelic Expression Imbalance Promoting a Mutant PEX6 Allele Causes Zellweger Spectrum Disorder. American Journal of Human Genetics, 101(6), 965-976. https://doi.org/10.1016/j.ajhg.2017.11.007

Rickenbacher, P., Kaufmann, B. A., Maeder, M. T., Bernheim, A., Goetschalckx, K., Pfister, O., Pfisterer, M., Brunner-La Rocca, H.-P., & Investigators, TIME.-CHF. (2017). Heart failure with mid-range ejection fraction: a distinct clinical entity? Insights from the Trial of Intensified versus standard Medical therapy in Elderly patients with Congestive Heart Failure (TIME-CHF). European journal of heart failure, 19(12), 1586-1596. https://doi.org/10.1002/ejhf.798

Baldewijns, K., Bektas, S., Boyne, J., Rohde, C., De Maesschalck, L., De Bleser, L., Brandenburg, V., Knackstedt, C., Deville, A., Sanders-Van Wijk, S., & La Rocca, H.-P. B. (2017). Improving kNowledge Transfer to Efficaciously RAise the level of Contemporary Treatment in Heart Failure (INTERACT-in-HF): Study protocol of a mixed methods study. International Journal of Care Coordination, 20(4), 171-182. https://doi.org/10.1177/2053434517726318

van Nieuwenhoven, F. A., Munts, C., op't Veld, R. C., Gonzalez, A., Diez, J., Heymans, S., Schroen, B., & van Bilsen, M. (2017). Cartilage intermediate layer protein 1 (CILP1): A novel mediator of cardiac extracellular matrix remodelling. Scientific Reports, 7, Article 16042. https://doi.org/10.1038/s41598-017-16201-y

Baumgartner, S., Mensink, R. P., Haenen, G. R., Bast, A., Binder, C. J., Bekers, O., Husche, C., Luetjohann, D., & Plat, J. (2017). The effects of vitamin E or lipoic acid supplementation on oxyphytosterols in subjects with elevated oxidative stress: a randomized trial. Scientific Reports, 7, Article 15288. https://doi.org/10.1038/s41598-017-15615-y

Dahlmans, D., Houzelle, A., Andreux, P., Jorgensen, J. A., Wang, X., de Windt, L. J., Schrauwen, P., Auwerx, J., & Hoeks, J. (2017). An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondrial metabolism. Molecular Metabolism, 6(11), 1429-1442. https://doi.org/10.1016/j.molmet.2017.08.007

Afsar, B., Rossignol, P., van Heerebeek, L., Paulus, W. J., Damman, K., Heymans, S., van Empel, V., Sag, A., Maisel, A., & Kanbay, M. (2017). Heart failure with preserved ejection fraction: a nephrologist-directed primer. Heart Failure Reviews, 22(6), 765-773. https://doi.org/10.1007/s10741-017-9619-2

van Vark, L. C., Lesman-Leegte, I., Baart, S. J., Postmus, D., Pinto, Y. M., Orsel, J. G., Westenbrink, B. D., Rocca, H. P. B., van Miltenburg, A. J. M., Boersma, E., Hillege, H. L., Akkerhuis, K. M., & TRIUMPH Investigators (2017). Prognostic Value of Serial ST2 Measurements in Patients With Acute Heart Failure. Journal of the American College of Cardiology, 70(19), 2378-2388. https://doi.org/10.1016/j.jacc.2017.09.026

Riemersma, M., Hazebroek, M. R., Helderman-van den Enden, A. T. J. M., Salomons, G. S., Ferdinandusse, S., Brouwers, M. C. G. J., van der Ploeg, L., Heymans, S., Glatz, J. F. C., van den Wijngaard, A., Krapels, I. P. C., Bierau, J., & Brunner, H. G. (2017). Propionic acidemia as a cause of adult-onset dilated cardiomyopathy. European Journal of Human Genetics, 25(11), 1195-1201. https://doi.org/10.1038/ejhg.2017.127

van Bilsen, M., Patel, H. C., Bauersachs, J., Boehm, M., Borggrefe, M., Brutsaert, D., Coats, A. J. S., de Boer, R. A., de Keulenaer, G., Filippatos, G. S., Floras, J., Grassi, G., Jankowska, E. A., Kornet, L., Lunde, I. G., Maack, C., Mahfoud, F., Pollesello, P., Ponikowski, P., ... Lyon, A. R. (2017). The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 19(11), 1361-1378. https://doi.org/10.1002/ejhf.921

D'Souza, A., Pearman, C. M., Wang, Y., Nakao, S., Logantha, S. J. R. J., Cox, C., Bennett, H., Zhang, Y., Johnsen, A. B., Linscheid, N., Poulsen, P. C., Elliott, J., Coulson, J., McPhee, J., Robertson, A., Martins, P. A. D. C., Kitmitto, A., Wisloff, U., Cartwright, E. J., ... Boyett, M. R. (2017). Targeting miR-423-5p Reverses Exercise Training-Induced HCN4 Channel Remodeling and Sinus Bradycardia. Circulation Research, 121(9), 1058-1068. https://doi.org/10.1161/CIRCRESAHA.117.311607

da Costa Martins, P. A. (2017). Mononuclear Diploidy at the Heart of Cardiomyocyte Proliferation. Cell Stem Cell, 21(4), 421-422. https://doi.org/10.1016/j.stem.2017.09.012

Vrolijk, M. F., Opperhuizen, A., Jansen, E. H. J. M., Hageman, G. J., Bast, A., & Haenen, G. R. M. M. (2017). The vitamin B6 paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6 function. Toxicology in Vitro, 44, 206-212. https://doi.org/10.1016/j.tiv.2017.07.009

Sthijns, M. M. J. P. E., den Hartog, G. J. M., Scasso, C., Haenen, J. P., Bast, A., & Haenen, G. R. M. M. (2017). Activation versus inhibition of microsomal glutathione S-transferase activity by acrolein. Dependence on the concentration and time of acrolein exposure. Chemico-Biological Interactions, 275, 116-120. https://doi.org/10.1016/j.cbi.2017.08.001

Caforio, A. L. P., Adler, Y., Agostini, C., Allanore, Y., Anastasakis, A., Arad, M., Boehm, M., Charron, P., Elliott, P. M., Eriksson, U., Felix, S. B., Garcia-Pavia, P., Hachulla, E., Heymans, S., Imazio, M., Klingel, K., Marcolongo, R., Cerinic, M. M., Pantazis, A., ... Linhart, A. (2017). Diagnosis and management of myocardial involvement in systemic immune-mediated diseases: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Disease. European Heart Journal, 38(35), 2649-2662. https://doi.org/10.1093/eurheartj/ehx321

Lorenzon, A., Calore, M., Poloni, G., De Windt, L. J., Braghetta, P., & Rampazzo, A. (2017). Wnt/beta-catenin pathway in arrhythmogenic cardiomyopathy. Oncotarget, 8(36), 60640-60655. https://doi.org/10.18632/oncotarget.17457

Heggermont, W. A., Papageorgiou, A.-P., Quaegebeur, A., Deckx, S., Carai, P., Verhesen, W., Eelen, G., Schoors, S., van Leeuwen, R., Alekseev, S., Elzenaar, I., Vinckier, S., Pokreisz, P., Walravens, A.-S., Gijsbers, R., Van Den Haute, C., Nickel, A., Schroen, B., van Bilsen, M., ... Heymans, S. (2017). Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction. Circulation, 136(8), 747-761. https://doi.org/10.1161/CIRCULATIONAHA.116.024171

van Gisbergen, M. W., Voets, A. M., Biemans, R., Hoffmann, R. F., Drittij-Reijnders, M.-J., Haenen, G. R. M. M., Heijink, I. H., Rouschop, K. M. A., Dubois, L. J., & Lambin, P. (2017). Distinct radiation responses after in vitro mtDNA depletion are potentially related to oxidative stress. PLOS ONE, 12(8), Article 0182508. https://doi.org/10.1371/journal.pone.0182508

Abdurrachim, D., Nabben, M., Hoerr, V., Kuhlmann, M. T., Bovenkamp, P., Ciapaite, J., Geraets, I. M. E., Coumans, W., Luiken, J. J. F. P., Glatz, J. F. C., Schaefers, M., Nicolay, K., Faber, C., Hermann, S., & Prompers, J. J. (2017). Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. Cardiovascular Research, 113(10), 1148-1160. https://doi.org/10.1093/cvr/cvx100

Uszko-Lencer, N. H. M. K., Mesquita, R., Janssen, E., Werter, C., Rocca, H.-P. B.-L., Pitta, F., Wouters, E. F. M., & Spruit, M. A. (2017). Reliability, construct validity and determinants of 6-minute walk test performance in patients with chronic heart failure. International Journal of Cardiology, 240, 285-290. https://doi.org/10.1016/j.ijcard.2017.02.109

van der Harst, P., de Windt, L. J., & Chambers, J. C. (2017). Translational Perspective on Epigenetics in Cardiovascular Disease. Journal of the American College of Cardiology, 70(5), 590-606. https://doi.org/10.1016/j.jacc.2017.05.067

Kramers, C., Janssen, B. J., Knol, W., Hessel, M. H. M., Mulder, W. M., Dumont, G., van den Brink, A. M., & Tichelaar, J. (2017). A Licence to Prescribe. British Journal of Clinical Pharmacology, 83(8), 1860-1861. https://doi.org/10.1111/bcp.13257

Lemkens, P., Spijkers, L. J. A., Meens, M. J., Nelissen, J., Janssen, B., Peters, S. L. M., Schiffers, P. M. H., & De Mey, J. G. R. (2017). Dual NEP/ECE inhibition improves endothelial function in mesenteric resistance arteries of 32-week-old SHR. Hypertension Research, 40(8), 738-745. https://doi.org/10.1038/hr.2017.38

Gromme, M., Russcher, H., Braakman, E., Klinkspoor, J. H., Dobber, J. A., de Greef, I., & de Wit, N. C. J. (2017). Multicenter study to evaluate a new enumeration method for hematopoietic stem cell collection management. Transfusion, 57(8), 1949-1955. https://doi.org/10.1111/trf.14183

Calore, M. (2017). The PRKAG2 gene and hypertrophic cardiomyopathy: an energetically imbalanced relationship. American Journal of Physiology-heart and Circulatory Physiology, 313(2), H248-H250. https://doi.org/10.1152/ajpheart.00316.2017

Zucker, I. H., Lindsey, M. L., Delmar, M., De Windt, L. J., Rosiers, C. D., Diz, D. I., Hester, R. L., Jones, S. P., Kanagy, N. L., Kitakaze, M., Liao, R., Lopaschuk, G. D., Patel, K. P., Recchia, F. A., Sadoshima, J., Shah, A. M., Ungvari, Z., Benjamin, I. J., Blaustein, M. P., ... Wolin, M. S. (2017). Why publish in the American Journal of Physiology-Heart and Circulatory Physiology?American Journal of Physiology-heart and Circulatory Physiology, 313(2), H221-H223. https://doi.org/10.1152/ajpheart.00329.2017

Benedikter, B. J., Volgers, C., van Eijck, P. H., Wouters, E. F. M., Savelkoul, P. H. M., Reynaert, N. L., Haenen, G. R. M. M., Rohde, G. G. U., Weseler, A. R., & Stassen, F. R. M. (2017). Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants. Free Radical Biology and Medicine, 108, 334-344. https://doi.org/10.1016/j.freeradbiomed.2017.03.026

Sharma, U. C., Mosleh, W., Chaudhari, M. R., Katkar, R., Weil, B., Evelo, C., Cimato, T. R., Pokharel, S., Blankesteijn, W. M., & Suzuki, G. (2017). Myocardial and Serum Galectin-3 Expression Dynamics Marks Post-Myocardial Infarction Cardiac Remodelling. Heart Lung and Circulation, 26(7), 736-745. https://doi.org/10.1016/j.hlc.2016.11.007

Harjola, V.-P., Mullens, W., Banaszewski, M., Bauersachs, J., Brunner-La Rocca, H.-P., Chioncel, O., Collins, S. P., Doehner, W., Filippatos, G. S., Flammer, A. J., Fuhrmann, V., Lainscak, M., Lassus, J., Legrand, M., Masip, J., Mueller, C., Papp, Z., Parissis, J., Platz, E., ... Mebazaa, A. (2017). Organ dysfunction, injury and failure in acute heart failure: from pathophysiology to diagnosis and management. A review on behalf of the Acute Heart Failure Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). European journal of heart failure, 19(7), 821-836. https://doi.org/10.1002/ejhf.872

Rienks, M., Carai, P., Bitsch, N., Schellings, M., Vanhaverbeke, M., Verjans, J., Cuijpers, I., Heymans, S., & Papageorgiou, A. (2017). Sema3A promotes the resolution of cardiac inflammation after myocardial infarction. Basic Research in Cardiology, 112(4), Article 42. https://doi.org/10.1007/s00395-017-0630-5

Hilderink, J. M., Klinkenberg, L. J. J., Aakre, K. M., de Wit, N. C. J., Henskens, Y. M. C., van der Linden, N., Bekers, O., Rennenberg, R. J. M. W., Koopmans, R. P., & Meex, S. J. R. (2017). Within-day biological variation and hour-to-hour reference change values for hematological parameters. Clinical Chemistry and Laboratory Medicine, 55(7), 1013-1024. https://doi.org/10.1515/cclm-2016-0716

Ottaviani, L., & da Costa Martins, P. A. (2017). Non-coding RNAs in cardiac hypertrophy. Journal of Physiology, 595(12), 4037-4050. https://doi.org/10.1113/JP273129

Perrino, C., Barabasi, A.-L., Condorelli, G., Davidson, S. M., De Windt, L., Dimmeler, S., Engel, F. B., Hausenloy, D. J., Hill, J. A., Van Laake, L. W., Lecour, S., Leor, J., Madonna, R., Mayr, M., Prunier, F., Sluijter, J. P. G., Schulz, R., Thum, T., Ytrehus, K., & Ferdinandy, P. (2017). Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heartd. Cardiovascular Research, 113(7), 725-736. https://doi.org/10.1093/cvr/cvx070

Liu, Y., Steinbusch, L. K. M., Nabben, M., Kapsokalyvas, D., van Zandvoort, M., Schonleitner, P., Antoons, G., Simons, P. J., Coumans, W. A., Geomini, A., Chanda, D., Glatz, J. F. C., Neumann, D., & Luiken, J. J. F. P. (2017). Palmitate-Induced Vacuolar-Type H(+)-ATPase Inhibition Feeds Forward Into Insulin Resistance and Contractile Dysfunction. Diabetes, 66(6), 1521-1534. https://doi.org/10.2337/db16-0727

Robaeys, W., Bektas, S., Boyne, J., van Empel, V., Uszko-Lencer, N., Knackstedt, C., & Brunner-La Rocca, H. P. (2017). Pulmonary and right ventricular dysfunction are frequently present in heart failure irrespective of left ventricular ejection fraction. Heart Asia, 9(2), 1-8. https://doi.org/10.1136/heartasia-2017-010914

Nabben, M., Schmitz, J. P. J., Ciapaite, J., le Clercq, C. M. P., van Riel, N. A., Haak, H. R., Nicolay, K., de Coo, I. F. M., Smeets, H., Praet, S. F., van Loon, L. J., & Prompers, J. J. (2017). Dietary nitrate does not reduce oxygen cost of exercise or improve muscle mitochondrial function in patients with mitochondrial myopathy. American Journal of Physiology-regulatory Integrative and Comparative Physiology, 312(5), R689-R701. https://doi.org/10.1152/ajpregu.00264.2016

Bektas, S., Franssen, F. M. E., van Empel, V., Uszko-Lencer, N., Boyne, J., Knackstedt, C., & Brunner-La Rocca, H. P. (2017). Impact of airflow limitation in chronic heart failure. Netherlands Heart Journal, 25(5), 335-342. https://doi.org/10.1007/s12471-017-0965-4

Uitterdijk, A., Springeling, T., Hermans, K. C. M., Merkus, D., de Beer, V. J., Gorsse-Bakker, C., Mokelke, E., Daskalopoulos, E. P., Wielopolski, P. A., Cleutjens, J. P. M., Blankesteijn, W. M., Prinzen, F. W., van der Giessen, W. J., van Geuns, R.-J. M., & Duncker, D. J. (2017). Intermittent pacing therapy favorably modulates infarct remodeling. Basic Research in Cardiology, 112(3), Article 28. https://doi.org/10.1007/s00395-017-0616-3

Meani, P., Gelsomino, S., Natour, E., Johnson, D. M., Rocca, H.-P. B. L., Pappalardo, F., Bidar, E., Makhoul, M., Raffa, G., Heuts, S., Lozekoot, P., Kats, S., Sluijpers, N., Schreurs, R., Delnoij, T., Montalti, A., Sels, J. W., van de Poll, M., Roekaerts, P., ... Lorusso, R. (2017). Modalities and Effects of Left Ventricle Unloading on Extracorporeal Life support: a Review of the Current Literature. European journal of heart failure, 19 Suppl 2, 84-91. https://doi.org/10.1002/ejhf.850

Davarzani, N., van Wijk, S., Karel, J., Maeder, M. T., Leibundgut, G., Gutmann, M., Pfisterer, M. E., Rickenbacher, P., Peeters, R., & Brunner-La Rocca, H. (2017). N-Terminal Pro-B-Type Natriuretic Peptide-Guided Therapy in Chronic Heart Failure Reduces Repeated Hospitalizations-Results From TIME-CHF. Journal of Cardiac Failure, 23(5), 382-389. https://doi.org/10.1016/j.cardfail.2017.02.001

Sthijns, M. M. J. P. E., Schiffers, P. M., Janssen, G. M., Lemmens, K. J. A., Ides, B., Vangrieken, P., Bouwman, F. G., Mariman, E. C., Pader, I., Arner, E. S. J., Johansson, K., Bast, A., & Haenen, G. R. M. M. (2017). Rutin protects against H₂O₂-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress. Biochimica et Biophysica Acta-general Subjects, 1861(5), 1177-1189. https://doi.org/10.1016/j.bbagen.2017.03.004

Veugen, M. G. J., Henry, R. M. A., van Sloten, T. T., Hermeling, E., Brunner-La Rocca, H.-P., Schram, M. T., Dagnelie, P. C., Schalkwijk, C. G., Kroon, A. A., Stehouwer, C. D. A., & Reesink, K. D. (2017). The systolic-diastolic difference in carotid stiffness is increased in type 2 diabetes: The Maastricht Study. Journal of Hypertension, 35(5), 1052-1060. https://doi.org/10.1097/HJH.0000000000001298

Chanda, D., Oligschlaeger, Y., Geraets, I., Liu, Y., Zhu, X., Li, J., Nabben, M., Coumans, W., Luiken, J. J. F. P., Glatz, J. F. C., & Neumann, D. (2017). 2-Arachidonoylglycerol ameliorates inflammatory stress-induced insulin resistance in cardiomyocytes. Journal of Biological Chemistry, 292(17), 7105-7114. https://doi.org/10.1074/jbc.M116.767384

Shi, Q., Boots, A. W., Maas, L., Veith, C., van Kuijk, K., Haenen, G. R., Godschalk, R. W., & Van Schooten, F. J. (2017). Effect of interleukin (IL)-8 on benzo[a]pyrene metabolism and DNA damage in human lung epithelial cells. Toxicology, 381, 64-74. https://doi.org/10.1016/j.tox.2017.02.013

van Empel, V., Knackstedt, C., van Paassen, P., & Brunner-La Rocca, H.-P. (2017). Just air good enough in pulmonary hypertension?European Heart Journal, 38(15), 1169-1171. https://doi.org/10.1093/eurheartj/ehx117

Emans, T. W., Janssen, B. J., Joles, J. A., & Krediet, C. T. P. (2017). Circadian Rhythm in Kidney Tissue Oxygenation in the Rat. Frontiers in physiology, 8, Article 205. https://doi.org/10.3389/fphys.2017.00205

Woudstra, L., Biesbroek, P. S., Emmens, R. W., Heymans, S., Juffermans, L. J., van Rossum, A. C., Niessen, H. W. M., & Krijnen, P. A. J. (2017). Lymphocytic myocarditis occurs with myocardial infarction and coincides with increased inflammation, hemorrhage and instability in coronary artery atherosclerotic plaques. International Journal of Cardiology, 232, 53-62. https://doi.org/10.1016/j.ijcard.2017.01.052