• 2020
    • Vangrieken, P., Remels, A. H., Al-Nasiry, S., Bast, A., Janssen, G. M. J., von Rango, U., Vroomans, D., Pinckers, Y. C. W., van Schooten, F. J., & Schiffers, P. M. H. (2020). Placental hypoxia-induced alterations in vascular function, morphology, and endothelial barrier integrity. Hypertension Research, 43(12), 1361-1374. https://doi.org/10.1038/s41440-020-0528-8
    • Reinhold, S., Blankesteijn, W. M., & Foulquier, S. (2020). The Interplay of WNT and PPAR gamma Signaling in Vascular Calcification. Cells, 9(12), [2658]. https://doi.org/10.3390/cells9122658
    • Mastenbroek, T. G., Karel, M. F. A., Nagy, M., Chayoua, W., Korsten, E. I. J., Coenen, D. M., Debets, J., Konings, J., Brouns, A. E., Leenders, P. J. A., van Essen, H., van Oerle, R., Heitmeier, S., Spronk, H. M., Kuijpers, M. J. E., & Cosemans, J. M. E. M. (2020). Vascular protective effect of aspirin and rivaroxaban upon endothelial denudation of the mouse carotid artery. Scientific Reports, 10(1), [19360]. https://doi.org/10.1038/s41598-020-76377-8
    • de Abreu, R. C., Fernandes, H., Martins, P. A. D. C., Sahoo, S., Emanueli, C., & Ferreira, L. (2020). Native and bioengineered extracellular vesicles for cardiovascular therapeutics. Nature Reviews Cardiology, 17(11), 685-697. https://doi.org/10.1038/s41569-020-0389-5
    • Remmelzwaal, S., van Ballegooijen, A. J., Schoonmade, L. J., Dal Canto, E., Handoko, M. L., Henkens, M. T. H. M., van Empel, V., Heymans, S. R. B., & Beulens, J. W. J. (2020). Natriuretic peptides for the detection of diastolic dysfunction and heart failure with preserved ejection fraction-a systematic review and meta-analysis. BMC Medicine, 18(1), [290]. https://doi.org/10.1186/s12916-020-01764-x
    • Breetveld, N. M., Alers, R-J., Geerts, L., van Kuijk, S. M. J., van Dijk, A. P., van der Vlugt, M. J., Heidema, W. M., van Neer, J., van Empel, V. P. M., Brunner-La Rocca, H-P., Scholten, R. R., Ghossein-Doha, C., & Spaanderman, M. E. A. (2020). Low Plasma Volume and Increased Pressure Load Relate to Concentric Left Ventricular Remodeling After Preeclampsia: A Longitudinal Study. Journal of the American Heart Association, 9(19), [015043]. https://doi.org/10.1161/JAHA.119.015043
    • Selevsek, N., Caiment, F., Nudischer, R., Gmuender, H., Agarkova, I., Atkinson, F. L., Bachmann, I., Baier, V., Barel, G., Bauer, C., Boerno, S., Bosc, N., Clayton, O., Cordes, H., Deeb, S., Gotta, S., Guye, P., Hersey, A., Hunter, F. M. I., ... Kleinjans, J. (2020). Network integration and modelling of dynamic drug responses at multi-omics levels. Communications Biology, 3(1), [573]. https://doi.org/10.1038/s42003-020-01302-8
    • Verdonschot, J. A. J., Hazebroek, M. R., Krapels, I. P. C., Henkens, M. T. H. M., Raafs, A., Wang, P., Merken, J. J., Claes, G. R. F., Vanhoutte, E. K., van den Wijngaard, A., Heymans, S. R. B., & Brunner, H. G. (2020). Implications of Genetic Testing in Dilated Cardiomyopathy. Circulation: Genomic and Precision Medicine, 13(5), 476-487. https://doi.org/10.1161/CIRCGEN.120.003031
    • Timmermans, P., Barradas-Pires, A., Ali, O., Henkens, M., Heymans, S., & Negishi, K. (2020). Prednisone and azathioprine in patients with inflammatory cardiomyopathy: systematic review and meta-analysis. Esc heart failure, 7(5), 2278-2296. https://doi.org/10.1002/ehf2.12762
    • van Veldhuisen, D. J., van Woerden, G., Gorter, T. M., van Empel, V. P. M., Manintveld, O. C., Tieleman, R. G., Maass, A. H., Vernooy, K., Westenbrink, B. D., van Gelder, I. C., & Rienstra, M. (2020). Ventricular tachyarrhythmia detection by implantable loop recording in patients with heart failure and preserved ejection fraction: the VIP-HF study. European journal of heart failure, 22(10), 1923-1929. https://doi.org/10.1002/ejhf.1970
    • Kesidou, D., Martins, P. A. D. C., de Windt, L. J., Brittan, M., Beqqali, A., & Baker, A. H. (2020). Extracellular Vesicle miRNAs in the Promotion of Cardiac Neovascularisation. Frontiers in physiology, 11, [579892]. https://doi.org/10.3389/fphys.2020.579892
    • Verdonschot, J. A. J., Derks, K. W. J., Hazebroek, M. R., Wang, P., Robinson, E. L., Adriaens, M. E., Krapels, I. P. C., van den Wijngaard, A., Brunner, H. G., & Heymans, S. R. B. (2020). Distinct Cardiac Transcriptomic Clustering in Titin and Lamin A/C-Associated Dilated Cardiomyopathy Patients. Circulation, 142(12), 1230-1232. https://doi.org/10.1161/CIRCULATIONAHA.119.045118
    • Videira, R. F., & da Costa Martins, P. A. (2020). Non-coding RNAs in Cardiac Intercellular Communication. Frontiers in physiology, 11, [738]. https://doi.org/10.3389/fphys.2020.00738
    • Tocchetti, C. G., Ameri, P., de Boer, R. A., D'Alessandra, Y., Russo, M., Sorriento, D., Ciccarelli, M., Kiss, B., Bertrand, L., Dawson, D., Falcao-Pires, I., Giacca, M., Hamdani, N., Linke, W. A., Mayr, M., van der Velden, J., Zacchigna, S., Ghigo, A., Hirsch, E., ... Thum, T. (2020). Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs: novel cardio-oncology insights from the joint 2019 meeting of the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart. Cardiovascular Research, 116(11), 1820-1834. https://doi.org/10.1093/cvr/cvaa222
    • Bar, C., Chatterjee, S., Pires, I. F., Rodrigues, P., Sluijter, J. P. G., Boon, R. A., Nevado, R. M., Andres, V., Sansonetti, M., de Windt, L., Ciccarelli, M., Hamdani, N., Heymans, S., Videira, R. F., Tocchetti, C. G., Giacca, M., Zacchigna, S., Engelhardt, S., Dimmeler, S., ... Thum, T. (2020). Non-coding RNAs: update on mechanisms and therapeutic targets from the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart. Cardiovascular Research, 116(11), 1805-1819. https://doi.org/10.1093/cvr/cvaa195
    • Prando, V., Bertoli, S., Favaro, G., Guescini, M., Di Mauro, V., Di Bona, A., Lo Verso, F., Soares, R., Dokshokova, L., Martins, P. D. C., Capri, M., Salvioli, S., Franceschi, C., Catalucci, D., Mongillo, M., Sandri, M., & Zaglia, T. (2020). Circulating muscle-derived MIR-206 links skeletal muscle dysfunction to cardiac autonomic denervation. Vascular Pharmacology, 132, [106742]. https://doi.org/10.1016/j.vph.2020.106742
    • Celutkiene, J., Pudil, R., Lopez-Fernandez, T., Grapsa, J., Nihoyannopoulos, P., Bergler-Klein, J., Cohen-Solal, A., Farmakis, D., Tocchetti, C. G., von Haehling, S., Barberis, V., Flachskampf, F. A., Ceponiene, I., Haegler-Laube, E., Suter, T., Lapinskas, T., Prasad, S., de Boer, R. A., Wechalekar, K., ... Lyon, A. R. (2020). Role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the European Society of Cardiology (ESC). European journal of heart failure, 22(9), 1504-1524. https://doi.org/10.1002/ejhf.1957
    • Seferovic, P. M., Fragasso, G., Petrie, M., Mullens, W., Ferrari, R., Thum, T., Bauersachs, J., Anker, S. D., Ray, R., Cavusoglu, Y., Polovina, M., Metra, M., Ambrosio, G., Prasad, K., Seferovic, J., Jhund, P. S., Dattilo, G., Celutkiene, J., Piepoli, M., ... Rosano, G. M. C. (2020). Sodium-glucose co-transporter 2 inhibitors in heart failure: beyond glycaemic control. A position paper of the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 22(9), 1495-1503. https://doi.org/10.1002/ejhf.1954
    • Stienen, S., Ferreira, J. P., Kobayashi, M., Preud'homme, G., Dobre, D., Machu, J-L., Duarte, K., Bresso, E., Devignes, M-D., Andres, N. L., Girerd, N., Aakhus, S., Ambrosio, G., Rocca, H-P. B-L., Fontes-Carvalho, R., Fraser, A. G., van Heerebeek, L., de Keulenaer, G., Marino, P., ... Rossignol, P. (2020). Sex differences in circulating proteins in heart failure with preserved ejection fraction. Biology of Sex Differences, 11(1), [47]. https://doi.org/10.1186/s13293-020-00322-7
    • Wagner, M., Bertero, E., Nickel, A., Kohlhaas, M., Gibson, G. E., Heggermont, W., Heymans, S., & Maack, C. (2020). Selective NADH communication from alpha-ketoglutarate dehydrogenase to mitochondrial transhydrogenase prevents reactive oxygen species formation under reducing conditions in the heart. Basic Research in Cardiology, 115(5), [53]. https://doi.org/10.1007/s00395-020-0815-1
    • Kerkhofs, D., van Hagen, B. T., Milanova, I. V., Schell, K. J., van Essen, H., Wijnands, E., Goossens, P., Blankesteijn, W. M., Unger, T., Prickaerts, J., Biessen, E. A., van Oostenbrugge, R. J., & Foulquier, S. (2020). Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension. Theranostics, 10(21), 9512-9527. https://doi.org/10.7150/thno.44394
    • Heggermont, W., Pham Anh Hong Nguyen, Lau, C-W., & Tournoy, K. (2020). A Steep Increase in the HeartLogic Index Predicts COVID-19 Disease in an Advanced Heart Failure Patient. Case reports in cardiology, 2020, [8896152]. https://doi.org/10.1155/2020/8896152
    • Ferro, D., van den Brink, H., Amier, R., van Buchem, M., de Bresser, J., Bron, E., Brunner-La Rocca, H-P., Hooghiemstra, A., Marcks, N., van Rossum, A., Biessels, G. J., & Heart-Brain Connection Consortium (2020). Cerebral cortical microinfarcts: A novel MRI marker of vascular brain injury in patients with heart failure. International Journal of Cardiology, 310, 96-102. https://doi.org/10.1016/j.ijcard.2020.04.032
    • Luiken, J. J. F. P., Nabben, M., Neumann, D., & Glatz, J. F. C. (2020). Understanding the distinct subcellular trafficking of CD36 and GLUT4 during the development of myocardial insulin resistance. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1866(7), [165775]. https://doi.org/10.1016/j.bbadis.2020.165775
    • Summer, G., Kuhn, A. R., Munts, C., Miranda-Silva, D., Leite-Moreira, A. F., Lourenco, A. P., Heymans, S., Falcao-Pires, I., & van Bilsen, M. (2020). A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF. Journal of Molecular and Cellular Cardiology, 144, 66-75. https://doi.org/10.1016/j.yjmcc.2020.05.008
    • Jusic, A., Salgado-Somoza, A., Paes, A. B., Stefanizzi, F. M., Martinez-Alarcon, N., Pinet, F., Martelli, F., Devaux, Y., Robinson, E. L., Novella, S., & EU-CardioRNA COST Action (2020). Approaching Sex Differences in Cardiovascular Non-Coding RNA Research. International journal of molecular sciences, 21(14), [4890]. https://doi.org/10.3390/ijms21144890
    • Santos-Faria, J., Gavina, C., Rodrigues, P., Coelho, J., Martins, P. D. C., Leite-Moreira, A., & Falcao-Pires, I. (2020). MicroRNAs and ventricular remodeling in aortic stenosis. Revista portuguesa de cardiologia, 39(7), 377-387. https://doi.org/10.1016/j.repc.2019.09.014
    • Linssen, P. B. C., Brunner-La Rocca, H-P., Schalkwijk, C. G., Beulens, J. W. J., Elders, P. J. M., Van der Heijden, A. A., Slieker, R. C., Stehouwer, C. D. A., & Henry, R. M. A. (2020). Serum Matrix Metalloproteinases and Left Atrial Remodeling-The Hoorn Study. International journal of molecular sciences, 21(14), [4944]. https://doi.org/10.3390/ijms21144944
    • Linssen, P. B. C., Veugen, M. G. J., Henry, R. M. A., van Der Kallen, C. J. H., Kroon, A. A., Schram, M. T., Brunner-La Rocca, H-P., & Stehouwer, C. D. A. (2020). Associations of (pre)diabetes with right ventricular and atrial structure and function: the Maastricht Study. Cardiovascular Diabetology, 19(1), [88]. https://doi.org/10.1186/s12933-020-01055-y
    • Verdonschot, J. A. J., Vanhoutte, E. K., Claes, G. R. F., van den Enden, A. T. J. M. H., Hoeijmakers, J. G. J., Hellebrekers, D. M. E. I., Haan, A. D., Christiaans, I., Deprez, R. H. L., Boen, H. M., Craenenbroeck, E. M. V., Loeys, B. L., Hoedemaekers, Y. M., Marcelis, C., Kempers, M., Brusse, E., Waning, J. I., Baas, A. F., Dooijes, D., ... Brunner, H. G. (2020). A mutation update for the FLNC gene in myopathies and cardiomyopathies. Human Mutation, 41(6), 1091-1111. https://doi.org/10.1002/humu.24004
    • Manukjan, N., Ahmed, Z., Fulton, D., Blankesteijn, W. M., & Foulquier, S. (2020). A Systematic Review of WNT Signaling in Endothelial Cell Oligodendrocyte Interactions: Potential Relevance to Cerebral Small Vessel Disease. Cells, 9(6), [1545]. https://doi.org/10.3390/cells9061545
    • Robinson, E. L., Gomes, C. P. C., Potocnjak, I., Hellemans, J., Betsou, F., de Gonzalo-Calvo, D., Stoll, M., Yilmaz, M. B., Agg, B., Beis, D., Carmo-Fonseca, M., Enguita, F. J., Dogan, S., Tuna, B. G., Schroen, B., Ammerlaan, W., Kuster, G. M., Carpusca, I., Pedrazzini, T., ... EU-CardioRNA COST Action (2020). A Year in the Life of the EU-CardioRNA COST Action: CA17129 Catalysing Transcriptomics Research in Cardiovascular Disease. Non-coding RNA, 6(2), [17]. https://doi.org/10.3390/ncrna6020017
    • Suthahar, N., Meems, L. M. G., van Veldhuisen, D. J., Walter, J. E., Gansevoort, R. T., Heymans, S., Schroen, B., van der Harst, P., Kootstra-Ros, J. E., van Empel, V., Mueller, C., Bakker, S. J. L., & de Boer, R. A. (2020). High-Sensitivity Troponin-T and Cardiovascular Outcomes in the Community: Differences Between Women and Men. Mayo Clinic Proceedings, 95(6), 1158-1168. https://doi.org/10.1016/j.mayocp.2020.01.017
    • Cuijpers, I., Simmonds, S. J., van Bilsen, M., Czarnowska, E., Miqueo, A. G., Heymans, S., Kuhn, A. R., Mulder, P., Ratajska, A., Jones, E. A., & Brakenhielm, E. (2020). Microvascular and lymphatic dysfunction in HFpEF and its associated comorbidities. Basic Research in Cardiology, 115(4), [39]. https://doi.org/10.1007/s00395-020-0798-y
    • De Majo, F., Hegenbarth, J-C., Ruehle, F., Baer, C., Thum, T., de Boer, M., Duncker, D. J., Schroen, B., Armand, A-S., Stoll, M., & De Windt, L. J. (2020). Dichotomy between the transcriptomic landscape of naturally versus accelerated aged murine hearts. Scientific Reports, 10(1), [8136]. https://doi.org/10.1038/s41598-020-65115-9
    • Emanueli, C., Badimon, L., Martelli, F., Potočnjak, I., Carpusca, I., Robinson, E. L., & Devaux, Y. (2020). Call to action for the cardiovascular side of COVID-19: A call for cooperative action from the EU-CardioRNA COSTAction. European Heart Journal, 41(19), 1796-1797. https://doi.org/10.1093/eurheartj/ehaa301
    • Cannata, A., De Angelis, G., Boscutti, A., Normand, C., Artico, J., Gentile, P., Zecchin, M., Heymans, S., Merlo, M., & Sinagra, G. (2020). Arrhythmic risk stratification in non-ischaemic dilated cardiomyopathy beyond ejection fraction. Heart, 106(9), 656-664. https://doi.org/10.1136/heartjnl-2019-315942
    • Seferovic, P. M., Piepoli, M. F., Lopatin, Y., Jankowska, E., Polovina, M., Anguita-Sanchez, M., Stoerk, S., Lainscak, M., Milicic, D., Milinkovic, I., Filippatos, G., Coats, A. J. S., Anker, S., Backs, J., Bauersachs, J., Ben Gal, T., de Boer, R. A., Doehner, W., Celutkiene, J., ... Heart Failure Association Board of the European Society of Cardiology (2020). Heart Failure Association of the European Society of Cardiology Quality of Care Centres Programme: design and accreditation document. European journal of heart failure, 22(5), 763-774. https://doi.org/10.1002/ejhf.1784
    • Heggermont, W. A., Delrue, L., Dierickx, K., Dierckx, R., Verstreken, S., Goethals, M., Bartunek, J., & Vanderheyden, M. (2020). Low MicroRNA-126 Levels in Right Ventricular Endomyocardial Biopsies Coincide With Cardiac Allograft Vasculopathy in Heart Transplant Patients. Transplantation Direct, 6(5), [549]. https://doi.org/10.1097/TXD.0000000000000995
    • Vrolijk, M. F., van Essen, H., Opperhuizen, A., Bast, A., & Janssen, B. J. (2020). Haemodynamic effects of the flavonoid quercetin in rats revisited. British Journal of Pharmacology, 177(8), 1841-1852. https://doi.org/10.1111/bph.14955
    • Vonhoegen, I. G. C., el Azzouzi, H., Olieslagers, S., Vasilevich, A., de Boer, J., Tinahones, F. J., Martins, P. A. D. C., de Windt, L. J., & Murri, M. (2020). MiR-337-3p Promotes Adipocyte Browning by Inhibiting TWIST1. Cells, 9(4), [1056]. https://doi.org/10.3390/cells9041056
    • De Bortoli, M., Vio, R., Basso, C., Calore, M., Minervini, G., Angelini, A., Melacini, P., Vitiello, L., Vazza, G., Thiene, G., Tosatto, S., Corrado, D., Iliceto, S., Rampazzo, A., & Calore, C. (2020). Novel Missense Variant in MYL2 Gene Associated With Hypertrophic Cardiomyopathy Showing High Incidence of Restrictive Physiology. Circulation: Genomic and Precision Medicine, 13(2), [002824]. https://doi.org/10.1161/CIRCGEN.119.002824
    • Holwerda, A. M., Bouwman, F. G., Nabben, M., Wang, P., van Kranenburg, J., Gijsen, A. P., Burniston, J. G., Mariman, E. C. M., & van Loon, L. J. C. (2020). Endurance-Type Exercise Increases Bulk and Individual Mitochondria' Protein Synthesis Rates in Rats. International Journal of Sport Nutrition and Exercise Metabolism, 30(2), 153-164. https://doi.org/10.1123/ijsnem.2019-0281
    • Verdonschot, J. A. J., Wang, P., Van Bilsen, M., Hazebroek, M. R., Merken, J. J., Vanhoutte, E. K., Henkens, M. T. H. M., Van Den Wijngaard, A., Glatz, J. F. C., Krapels, I. P. C., Brunner, H. G., Heymans, S. R. B., & Bierau, J. (2020). Metabolic Profiling Associates with Disease Severity in Nonischemic Dilated Cardiomyopathy. Journal of Cardiac Failure, 26(3), 212-222. https://doi.org/10.1016/j.cardfail.2019.09.004
    • Peters, M. M. C., Sampaio-Pinto, V., & da Costa Martins, P. A. (2020). Non-coding RNAs in endothelial cell signalling and hypoxia during cardiac regeneration. Biochimica et Biophysica Acta-Molecular Cell Research, 1867(3), [118515]. https://doi.org/10.1016/j.bbamcr.2019.07.010
    • Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2020). Placental Mitochondrial Abnormalities Upon Hypoxia; The Cause of Placental Oxidative Stress?Reproductive Sciences, 27(SUPPL 1), 268A-268A.
    • Liapi, E., van Bilsen, M., Verjans, R., & Schroen, B. (2020). tRNAs and tRNA fragments as modulators of cardiac and skeletal muscle function. Biochimica et Biophysica Acta-Molecular Cell Research, 1867(3), [118465]. https://doi.org/10.1016/j.bbamcr.2019.03.012
    • Stienen, S., Ferreira, J. P., Kobayashi, M., Preud'homme, G., Dobre, D., Machu, J-L., Duarte, K., Bresso, E., Devignes, M-D., Lopez, N., Girerd, N., Aakhus, S., Ambrosio, G., Brunner-La Rocca, H-P., Fontes-Carvalho, R., Fraser, A. G., Van Heerebeek, L., Heymans, S., De Keulenaer, G., ... Rossignol, P. (2020). Enhanced clinical phenotyping by mechanistic bioprofiling in heart failure with preserved ejection fraction: insights from the MEDIA-DHF study (The Metabolic Road to Diastolic Heart Failure). Biomarkers, 25(2), 201-211. https://doi.org/10.1080/1354750X.2020.1727015
    • Verdonschot, J. A. J., Robinson, E. L., James, K. N., Mohamed, M. W., Claes, G. R. F., Casas, K., Vanhoutte, E. K., Hazebroek, M. R., Kringlen, G., Pasierb, M. M., van den Wijngaard, A., Glatz, J. F. C., Heymans, S. R. B., Krapels, I. P. C., Nahas, S., Brunner, H. G., & Szklarczyk, R. (2020). Mutations in PDLIM5 are rare in dilated cardiomyopathy but are emerging as potential disease modifiers. Molecular genetics & genomic medicine, 8(2), [e1049]. https://doi.org/10.1002/mgg3.1049
    • Barutaut, M., Fournier, P., Peacock, W. F., Evaristi, M. F., Caubere, C., Turkieh, A., Desmoulin, F., Eurlings, L. W. M., van Wijk, S., Brunner-La Rocca, H-P., Butler, J., Koukoui, F., Dambrin, C., Mazeres, S., Le Page, S., Delmas, C., Galinier, M., Jung, C., Smih, F., & Rouet, P. (2020). Insulin-like Growth Factor Binding Protein 2 predicts mortality risk in heart failure. International Journal of Cardiology, 300, 245-251. https://doi.org/10.1016/j.ijcard.2019.09.032