Publications
- 2026
- Chen, B., Prabhu, A., Li, G., Kaltenbach, A., Wang, Y., Shakir, G., Natarelli, L., Megens, R., Jansen, Y., Ramanathan, S., Geiger, M., Faussner, A., Hristov, M., Richter, D., Di, X., van der Stelt, M., Triantafyllidou, V., Li, Z., Sachs, N., ... Steffens, S. (2026). Endothelial cannabinoid CB1 receptor deficiency reduces shear stress-induced arterial inflammation and lipid uptake. Nature Communications, 17(1), Article 5939. https://doi.org/10.1038/s41467-026-75214-2
- Januzzi, J. L., Gibson, C. M., Chi, G., Coller, B. S., Granger, C. B., Montalescot, G., Rikken, S. A. O. F., Verburg, A., Berg, J. M. T., & van 't Hof, A. W. J. (2026). The effect of zalunfiban on high sensitivity cardiac troponin and the association with clinical outcomes in patients with STEMI. American Heart Journal, 301, Article 107513. https://doi.org/10.1016/j.ahj.2026.107513
- van Loo, C., Stevens, K. A., Sigaeva, T., Giudici, A., Schurgers, L. J., Delhaas, T., Au, J. S., & Spronck, B. (2026). Biaxial biomechanics of aged human carotid arteries. Journal of the Mechanical Behavior of Biomedical Materials, 182, Article 107529. https://doi.org/10.1016/j.jmbbm.2026.107529
- van Vliet, L., Zonnebeld, N., Delhaas, T., Ganesan, R., Huijsse, I., Mees, B., Tordoir, J., Huberts, W., & Snoeijs, M. (2026). Blood flow rate predictions in arteriovenous fistulas: Combining physics-based modelling with data-driven models. Journal of Computational Science, 100, Article 102966. https://doi.org/10.1016/j.jocs.2026.102966
- Zhazykbayeva, S., Hamdani, N., & El-Battrawy, I. (2026). Prime-edited isogenic hiPSC-cardiomyocytes model short QT syndrome type 3 and drug responses. Life Sciences, 402, Article 124602. https://doi.org/10.1016/j.lfs.2026.124602
- Vossen, S., van Osta, N., Lourenço, G. P. C., Laranjo, S. M., & Lumens, J. (2026). Calcium-mediated force-interval relationship drives post-extrasystolic potentiation in premature ventricular complexes: a computational study. Biomechanics and modeling in mechanobiology, 25(5), Article 96. https://doi.org/10.1007/s10237-026-02119-w
- Schotten, U., & Kirchhof, P. (2026). Quantifying atrial fibrillation to improve risk estimation: the growing role of AF burden and a new density kid on the block. European Heart Journal, 47(36), 5125-5127. https://doi.org/10.1093/eurheartj/ehag298
- Aerts, L., Norup Hertel, J., Hermans, B. J. M., Luermans, J. G. L., Chaldoupi, S.-M., Lans, R., Saljic, A., Maessen, J. G., Jespersen, T., Linz, D., & Maesen, B. (2026). Analysis of Ablation Curves to Predict Transmural Lesions Using an Epicardial Bipolar Irrigated Radiofrequency Clamp in Pigs and Humans. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery. Advance online publication. https://doi.org/10.1177/15569845261448874
- Iaconelli, A., Busti, M., Sensini, L., Dolce, P., Paglianiti, D. A., Scacciavillani, R., Montone, R. A., Lunardi, M., Pugliese, N. R., D'Amario, D., Laborante, R., Ruggio, A., Pecorini, G., Galli, M., Pellicori, P., Petrie, M., Lambiase, P. D., Crijns, H. J. G. M., Crea, F., & Cleland, J. G. F. (2026). Catheter ablation of atrial fibrillation in patients with heart failure: a trial-level meta-analysis. European journal of heart failure, Article xuag232. https://doi.org/10.1093/ejhf/xuag232
- Verpalen, V. A., Coerkamp, C. F., Hinderks, M. J., Meeder, J. G., Winter, M. M., Arkenbout, E. K., Vis, J. C., Habets, J., Smulders, M. W., Mihl, C., van Ofwegen-Hanekamp, C. E. E., van der Spoel, T. I. G., Tanis, W., van Gelder, R. E., van der Wielen, M. L. J., Somsen, G. A., Kikkert, W. J., Carati, L. F., el Barzouhi, A., ... CLEAR CAD Investigators (2026). Correction to: Combined strategy of upfront CTCA and optimal treatment for stable chest pain: rationale and design of the CLEAR-CAD trial. Netherlands Heart Journal, 34(9), 327-328. https://doi.org/10.1007/s12471-026-02071-5
- Janssen, S., Luijkx, J. J. P., Swinnen, W., Vriesendorp, P., ten Berg, J. M., van ‘t Hof, A. W. J., Rasoul, S., & SLIM-2 study group (2026). Direct oral anticoagulation interruption vs continuation in patients undergoing elective invasive coronary angiography or percutaneous coronary intervention: Design and rationale of the South Limburg Myocardial Infarction Study Group Trial 2 (SLIM-2). American Heart Journal, 299, Article 107462. https://doi.org/10.1016/j.ahj.2026.107462
- Xie, T., Ani, A., Vaez, A., Nolte, I. M., Su, S., Ishikuro, M., Wang, S., Zhang, W., Soares, A. G., Motazedi, E., Calas, L., Ronkainen, J., Pedersen, C.-E. T., Lu, X., Stinson, S. E., Felix, J. F., Stankevic, E., Wang, C. A., Thiering, E., ... Et al. (2026). Genetic determinants of childhood blood pressure and heart rate in relation to adult health outcomes: the consortium of childhood blood pressure. European Heart Journal, 47(33), 4621-4637. https://doi.org/10.1093/eurheartj/ehag313
- Jastrzebski, M., Shah, R., Bednarek, A., Cano, O., Sondej, T., Kielbasa, G., Moskal, P., Atallah, R., Vernooy, K., Rajzer, M., & Vijayaraman, P. (2026). Radiofrequency current-facilitated implantation of left bundle branch pacing lead for cardiac resynchronization therapy. Heart Rhythm, 23(9), e2060-e2068. https://doi.org/10.1016/j.hrthm.2026.03.1943
- Toonen, S. M. R. L., de Raat, F. M., van Loo, C., van Knippenberg, L., van Houte, J., Delhaas, T., Schurgers, L. J., Jeroncic, A., Mischi, M., Arthur Bouwman, R., Montenij, L. J., & Spronck, B. (2026). Vasoactive response of the thoracic aorta to phenylephrine infusion during cardiac surgery. Journal of Applied Physiology, 141(3), 863-872. https://doi.org/10.1152/japplphysiol.00996.2025
- Bovenkerk, D. S. H., La Fontaine, L. A., Hermans, A. N. L., van Kuijk, S. M. J., Joosten, I. B. T., Faber, C. G., Lankveld, T. A. R., den Uijl, D., Vernooy, K., Hendriks, J. M., Linz, D., & Hermans, B. J. M. (2026). Annual assessment of ECG intervals in patients with myotonic dystrophy type 1 using a mobile 6-lead ECG device: TeleCheck-DM1. IJC Heart and Vasculature, 66, Article 101996. Advance online publication. https://doi.org/10.1016/j.ijcha.2026.101996
- Pype, L. L., Marchenko, O., Van Laer, S. L., Paelinck, B. P., Boen, H. M., Sturkenboom, N., Masci, P. G., Ter Bekke, R. M. A., Grapsa, J., Volders, P. G. A., Van Craenenbroeck, E. M., & Van De Heyning, C. M. (2026). Left Ventricular Remodelling in Mitral Valve Prolapse: More Than Volume Overload. Circulation-Cardiovascular Imaging, 19(9), Article e019974. https://doi.org/10.1161/CIRCIMAGING.126.019974
- Keelani, A., Tavkhelidze, S., Lisica, L., Ruwald, M. H., Chaldoupi, S. M., Alothman, O., Borisov, G., Frommhold, M., Abdelwahab, H., Johannesen, A., Hansen, M., Worck, R., Haugdal, M., Raffa, S., Hansen, J., Linz, D., Anic, A., & Geller, J. C. (2026). Safety and Midterm Outcome of Focal Pulsed Field Ablation for Outflow Tract Premature Ventricular Contractions: A Prospective Multicenter Study. JACC: Clinical Electrophysiology, 12(9), 2120-2132. https://doi.org/10.1016/j.jacep.2026.03.032
- Milzi, A., Landi, A., Leonardi, S., Frazzetto, M., Covani, M., Frigoli, E., Vant'Hof, A. W. J., Vranckx, P., & Valgimigli, M. (2026). Impact of guidelines-directed very-high-risk criteria in the identification and management of occlusion myocardial infarction in patients with NSTE-ACS. European Heart Journal: Acute Cardiovascular Care, Article zuag096. https://doi.org/10.1093/ehjacc/zuag096
- Morch-Pedersen, M., Norregaard, M., Graff, C., Vad, O. B., Lundegaard, P. R., Svendsen, J. H., Hansen, T., Linneberg, A., Jorgensen, P. G., Jensen, M. T., Rossing, P., Ellervik, C., Linz, D., Thambawita, V., Maleckar, M. M., Riegler, M. A., Kanters, J. K., & Isaksen, J. L. (2026). Pooling cohorts for deep learning analysis: a potential source of bias for electrocardiogram analysis. Biomedical Signal Processing and Control, 122, Article 110424. https://doi.org/10.1016/j.bspc.2026.110424
- Roefs, M. M., Amoroso, G., Camaro, C., Daeter, E. J., Grundeken, M. J., van 't Hof, A. W. J., de Lind van Wijngaarden, R. A. F., Lipsic, E., Meuwissen, M., van der Harst, P., van Veghel, D., & Netherlands Heart Registration (2026). Cardiology in numbers: coronary artery disease in the Netherlands. Netherlands Heart Journal, 34(7-8), 283-284. https://doi.org/10.1007/s12471-026-02058-2
- Terron, M. C., Rossi, C., Krause, J., Schroen, B., Herum, K. M., & Nieuwenhoven, F. A. V. (2026). Cartilage intermediate layer protein (CILP) in cardiac fibrosis: Protective or pathogenic?Matrix Biology, 147, Article 102032. https://doi.org/10.1016/j.matbio.2026.102032
- Linz, D. (2026). Erythrocyte dysfunction in sleep-disordered breathing: a driver of vascular injury beyond reduced oxygen transport. European Heart Journal. Advance online publication. https://doi.org/10.1093/eurheartj/ehag567
- Peeters, D. A. M., Woelders, E. C. I., Janssen, S., Azzahhafi, J., Yin, D. R. P. P. C. P., van den Broek, W. W. A., Winkler, P. J. C., van de Pol, Q. Y. F., Cetinyurek-Yavuz, A., Damman, P., Luijkx, J. J. P., Remkes, W. S., van't Hof, A. W. J., ten Berg, J. M., & van Geuns, R. J. M. (2026). Lipid-lowering therapy omission at discharge and one-year outcomes after percutaneous coronary intervention: a real-world analysis of overall and elderly patients. IJC Heart and Vasculature, 65, Article 101961. https://doi.org/10.1016/j.ijcha.2026.101961
- Gold, C., Falagkari, A., Post, F., Johnson, V., Roth, E., Kühn, S. J., Linz, D., Dobrev, D., Erath-Honold, J., Rottner, L., Leistner, D. M., Kupusovic, J., & Wakili, R. (2026). PulseSelect vs FARAPULSE pulsed field ablation: Comparative analysis of myocardial, neural-injury and hemolysis biomarkers and short-term outcomes. IJC Heart and Vasculature, 65, Article 101957. https://doi.org/10.1016/j.ijcha.2026.101957
- De Koning, I. A., Heutinck, J. M., Buckley, B. J. R., Dibben, G. O., Campo, G., Hautala, A. J., Snoek, J. A., Maddison, R., Santaularia, N., Lear, S. A., Houle, J., Lip, G. Y. H., Van Geuns, R. J. M., Vromen, T., Kemps, H. M. C., Taylor, R. S., Stens, N. A., Thijssen, D. H. J., Hughes, A. D., ... CaReMATCH collaborators (2026). Exercise-based cardiac rehabilitation for patients with angina pectoris - a CaReMATCH individual participant data meta-analysis. American Journal of Preventive Cardiology, 28, Article 101535. https://doi.org/10.1016/j.ajpc.2026.101535
- Farnir, F. I. P., Luermans, J. G. L. M., Farnir, F. P. F. J. D. J., Chaldoupi, S. M., & Linz, D. (2026). Impedance drop during focal monopolar pulsed field ablation in the atrium. Journal of Interventional Cardiac Electrophysiology, 69(5), 801-803. https://doi.org/10.1007/s10840-024-01793-z
- Roodenburg, R., Verheul, L. M., Hoeksema, W. F., Evertz, R., Balt, J. C., Yap, S. C., Alings, M., Kapel, G. F. L., Bootsma, M., Mulder, B. A., van der Voort, P., Volders, P. G. A., Postema, P. G., Wilde, A. A. M., Meine, M., & Hassink, R. J. (2026). Implantable Cardioverter-Defibrillator Therapy and Implantable Cardioverter-Defibrillator Complications in Idiopathic Ventricular Fibrillation Patients. JACC: Clinical Electrophysiology, 12(8), 1896-1905. https://doi.org/10.1016/j.jacep.2026.02.026
- Engels, M. D. E. A., Rippens, M., Hermans, B. J. M., Sandgren, E., Luermans, J., Chaldoupi, S.-M., Hendriks, J. M. L., Lankveld, T., Kessels, M., Vorstermans, B. J. G. H., Beukema, R. J., Vernooy, K., Heesen, W., Hermans, A. N. L., & Linz, D. K. (2026). Smartphone app-based symptom assessment in patients with atrial fibrillation on the waiting list for electrical cardioversion: a TeleConvert-atrial fibrillation sub analysis. EP Europace, 28(8), Article euag201. https://doi.org/10.1093/europace/euag201
- Yilmaz, D., Egorova, A. D., Grauss, R., Spierenburg, H. A. M., Venooy, K., van Woerkens, L. P. M., de Medina, R. R., Schalij, M. J., & van Erven, L. (2026). The Dutch Implantable Cardioverter-Defibrillator Decision Aid in Clinical Practice: A Stepped-Wedge Randomized Controlled Trial. Medical Decision Making, 46(6), 744-756. https://doi.org/10.1177/0272989X261438122
- Homberg, M., Linz, D., Brandts, L., Joosten, E. A., Buhre, W., & Bouman, E. (2026). High-flow versus low-flow nasal oxygen during procedural sedation for atrial fibrillation ablation: A randomised controlled trial. European Journal of Anaesthesiology and Intensive Care, 5(4), Article e0129. https://doi.org/10.1097/EA9.0000000000000129
- Tangos, M., Schneider, L., Jarkas, O., El-Battrawy, I., & Hamdani, N. (2026). Extracellular Vesicles as Mediators of Pathophysiology and Disease Progression in Cardiovascular Diseases. International Journal of Molecular Sciences, 27(15), Article 6786. https://doi.org/10.3390/ijms27156786
- Daniels, F., Eerenberg, F., Kloosterman, M., van Stipdonk, A. M. W., Chiu, C. S. L., Meine, M., Vernooy, K., Rienstra, M., & Maass, A. H. (2026). QRS Area Before and After Upgrading to Cardiac Resynchronization Therapy Is Not Sufficient to Predict Outcome. Journal of Cardiovascular Development and Disease, 13(7), Article 331. https://doi.org/10.3390/jcdd13070331
- Streukens, S. A. F., Peeters, F. E. C. M., Theunissen, R. A. L. J., Welman, M. J. M., Mihl, C., Smulders, M. W., & Vriesendorp, P. A. (2026). Fatal Platypnea-Orthodeoxia Syndrome After Transcatheter Tricuspid Valve Replacement: When HALT Reverses the Shunt. JACC. Case reports, 31(27), Article 108368. https://doi.org/10.1016/j.jaccas.2026.108368
- Hashiba, M., Linz, D., Frandsen, R., Jennum, P., Grove, E. L., Gantzhorn, E., Al-Ansary, L., Nielsen, S. K., Al-Alak, A., Bille, J., Fuglsang, M., Tang, L. H., Korshoj, M., Risom, S. S., & Lamberts, M. (2026). VIR-SAAF: a study protocol for a national decentralised randomised controlled trial of home-based sleep apnoea screening in patients with atrial fibrillation in Denmark. BMJ Open, 16(7), Article e121645. https://doi.org/10.1136/bmjopen-2026-121645
- Marques, V. G., Gharaviri, A., Pezzuto, S., Guasch, E., Mont, L., Bonizzi, P., Zeemering, S., & Schotten, U. (2026). Analysis of the Effect of Anatomical Variability on Atrial Fibrillation Dynamics Through a Novel Framework for Personalised Atrial Model Generation. Annals of Biomedical Engineering. https://doi.org/10.1007/s10439-026-04265-9
- Meier, S., Dobrev, D., Volders, P. G. A., & Heijman, J. (2026). Computational modelling of the pro- and antiarrhythmic effects of atrial high rate-dependent trafficking of small-conductance calcium-activated potassium channels. Journal of Physiology, 604(13), 5355-5377. https://doi.org/10.1113/JP288659
- Winters, J., Kawczynski, M., Gilbers, M., Isaacs, A., Zeemering, S., Habibi, Z., Rienstra, M., van Gelder, I., Maesen, B., Bidar, E., Verheule, S., & Schotten, U. (2026). Histological evaluation of clinically defined atrial cardiomyopathy stages and their association with atrial fibrillation burden under continuous monitoring for a 2.5-year follow-up. EP Europace, 28(7), Article euag146. https://doi.org/10.1093/europace/euag146
- Al-Taie, C., Obergassel, J., Borof, K., Ridder, J., Rillig, A., Metzner, A., Goette, A., Magnussen, C., Sinner, M. F., Sommerfeld, L. C., Willems, S., Zeller, T., Schnabel, R. B., Schotten, U., Zapf, A., Kirchhof, P., & Fabritz, L. (2026). Interactions of blood biomolecules with early rhythm control in atrial fibrillation patients: exploratory analysis of the EAST-AFNET 4 biomolecule study. EP Europace, 28(7), Article euag149. https://doi.org/10.1093/europace/euag149
- Rijks, J. H. J., van Koll, J., Burri, H., Curila, K., van Dijk, V. F., Hauer, A., van Opstal, J. M., de Pooter, J., Rademakers, L. M., Timmer, S. A. J., Wieringa, W., Essers, B. A. B., van Kuijk, S. M. J., Brunner-La Rocca, H.-P., Vernooy, K., & Luermans, J. (2026). Permanent LEft ventricular septAl Pacing vs. right ventricular pacing in patients with atrioventricular conduction disorders-a randomized trial: rationale and design of the LEAP trial. European heart journal open, 6(4), Article oeag108. https://doi.org/10.1093/ehjopen/oeag108
- Sobota, V., Stoks, J., Patel, K. H. K., Shetty, R., Ni, H., Grandi, E., Ng, F. S., Volders, P. G. A., Cluitmans, M. J. M., & Bayer, J. D. (2026). The apicobasal dispersion of ventricular repolarization in humans is associated with age and affects arrhythmia vulnerability. The Journal of Physiology, 604(13), 5260-5275. https://doi.org/10.1113/JP288356
- Smits, K. C., Lempers, T. E. M., Strik, M., Stoks, J., Meiburg, R., Cluitmans, M. J. M., Volders, P. G. A., Vernooy, K., Prinzen, F. W., & Nguyen, U. C. (2026). The influence of delayed ventricular activation on cardiac repolarization: Insights from electrocardiographic imaging. Journal of Physiology, 604(13), 5378-5390. https://doi.org/10.1113/JP288569
- van Koll, J., Ramalingam, V., Tai, P., Essebag, V., Nguyên, U. C., Opmeer, K. H. M., Lumens, J., Luermans, J. G. L. M., Vernooy, K., & Joza, J. (2026). Identifying Left Ventricular Posterolateral Wall Delay in Right Bundle Branch Block Patients Using Lead V8. JACC: Clinical Electrophysiology, 12(7), 1732-1734. https://doi.org/10.1016/j.jacep.2026.03.009
- van Veldhuisen, D. J., Rienstra, M., Mosterd, A., Alings, M., Voors, A. A., Damman, K., van Asselt, A. D. I., Bouvy, M. L., Schaap, J., van der Wall, E. E., Crijns, H. J. G. M., Touw, D. J., Hoogslag, P. A. M., van de Swaluw, J. E. C., Schuurman, R. J., van der Sluis, A., Bondarenko, O., Romer, T. J., Oosterhof, T., ... van der Meer, P. (2026). Low-dose digoxin in patients with heart failure with reduced or mildly reduced ejection fraction: a randomized controlled trial. Nature Medicine, 32(7), 2647-2653. https://doi.org/10.1038/s41591-026-04406-6
- ter Bekke, R., Kaya, Y., Pison, L., Evertz, R., Vernooy, K., Luermans, J., Vroomen, M., Jeurissen, J., Chaldoupi, M., Bidar, E., Lorusso, R., Sauren, B., Lameir, M., & Maesen, B. (2026). Patient-tailored minimally invasive hybrid ablation of complex ventricular tachycardia substrates. JACC: Clinical Electrophysiology, 12(7), 1544-1555. https://doi.org/10.1016/j.jacep.2026.02.031
- Heuts, S., de Keijzer, A. R., Adriaans, B. P., Notenboom, M. L., Mihl, C., Wildberger, J. E., Vos, R. J., Post, M. C., Rylski, B., Czerny, M., Reesink, K. D., Takkenberg, J. J. M., Veen, K. M., Arabkhani, B., Schalla, S. S., Schurgers, L. J., Lorusso, R., Hjortnaes, J., & Bidar, E. (2026). Rethinking Aortic Risk: The Potential Impact of Novel, Adjusted, and Combined Aortic Measures in the Prediction of Aortic Dissection. The Canadian journal of cardiology, 42(7), 1686-1696. https://doi.org/10.1016/j.cjca.2026.01.023
- Huygens, S., Versteegh, M., Hemels, M., Linz, D., Rienstra, M., & Yap, S.-C. (2026). The Cost Utility of Rhythm Control Treatment Sequences in Patients with Atrial Fibrillation: Anti-arrhythmic Drugs Versus Catheter Ablation. Pharmacoeconomics, 44(7), 865-878. https://doi.org/10.1007/s40273-026-01604-5
- Balogh, M., Tangos, M., Patel, V. S., Hamdani, N., & Bagi, Z. (2026). Extracellular Vesicles Link Cerebral Ischemia to Coronary Microvascular Dysfunction - Role for RGD Motif-Activated Endothelin Signaling. Journal of Cardiovascular Translational Research, 19(1), Article 77. https://doi.org/10.1007/s12265-026-10802-7
- Prinzen, F. W., & van der Vusse, G. J. (2026). Questionable metabolic flexibility during cardiac resynchronization therapy. European Heart Journal, 47(24), 3217. https://doi.org/10.1093/eurheartj/ehaf818
- Ayagama, T., Barrett-Jolley, R., Fischer, R., Hester, S. S., Schotten, U., Verheule, S., & Burton, R. A. B. (2026). Proteomic signatures of mitochondrial dysfunction associated with atrial fibrillation in goats. Scientific Reports, 16(1), Article 28023. https://doi.org/10.1038/s41598-026-58413-1
- Meng, Z., Kovacs, B., Yan, C., Holscher, C., Zhazykbayeva, S., Jarkas, O., Zou, C., Cyganek, L., Zorio, E., Braza-Boils, A., Pablo Ochoa, J., Rehbehn, N., Fan, X., Lei, X., Liu, R., Tong, S., Liu, F., Xue, Z., Bober, S. L., ... El-Battrawy, I. (2026). SLC4A3-related short QT syndrome assessed in human induced pluripotent stem cell-derived cardiomyocytes: mechanisms of ventricular arrhythmia and sudden cardiac death. European Heart Journal, 47(23), 2982-2998. https://doi.org/10.1093/eurheartj/ehag068




