• 2021
    • Herrera-Rivero, M., Stoll, M., Hegenbarth, J. C., Ruhle, F., Limperger, V., Junker, R., Franke, A., Hoffmann, P., Shneyder, M., Stach, M., & Nowak-Gottl, U. (2021). Single- and Multimarker Genome-Wide Scans Evidence Novel Genetic Risk Modifiers for Venous Thromboembolism. Thrombosis and Haemostasis, 121(09), 1169-1180. https://doi.org/10.1055/s-0041-1723988
    • van Gorp, R. H., Baaten, C. C. F. M. J., Habibi, A., Jaminon, A. M. G., Peeters, F. E. C. M., Leenders, P., Crijns, H. J. G. M. C., Heemskerk, J. W. M., Reutelingsperger, C. P., Spronk, H. M., & Schurgers, L. J. (2021). Vitamin K antagonist use induces calcification and atherosclerotic plaque progression resulting in increased hypercoagulability. European heart journal open, 1(2), Article oeab017. https://doi.org/10.1093/ehjopen/oeab017
    • Giesen, P. L. A., Gulpen, A. J. W., van Oerle, R., ten Cate, H., Nagy, M., & Spronk, H. M. H. (2021). Calibrated automated thrombogram II: removing barriers for thrombin generation measurements. Thrombosis Journal, 19(1), Article 60. https://doi.org/10.1186/s12959-021-00312-8
    • ten Cate, H. (2021). Surviving Covid-19 with Heparin?New England Journal of Medicine, 385(9), 845-846. https://doi.org/10.1056/NEJMe2111151
    • Huckriede, J., Anderberg, S. B., Morales, A., de Vries, F., Hultstrom, M., Bergqvist, A., Ortiz-Perez, J. T., Sels, J. W., Wichapong, K., Lipcsey, M., van de Poll, M., Larsson, A., Luther, T., Reutelingsperger, C., Garcia de Frutos, P., Frithiof, R., & Nicolaes, G. A. F. (2021). Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients. Scientific Reports, 11(1), Article 15701. https://doi.org/10.1038/s41598-021-95209-x
    • Hulshof, A. M., Braeken, D. C. W., Ghossein-Doha, C., van Santen, S., Sels, J. W. E. M., Kuiper, G. J. A. J. M., van der Horst, I. C. C., ten Cate, H., van Bussel, B. C. T., Olie, R. H., & Henskens, Y. M. C. (2021). Hemostasis and fibrinolysis in COVID-19 survivors 6 months after intensive care unit discharge. Research and practice in thrombosis and haemostasis, 5(6), Article e12579. https://doi.org/10.1002/rth2.12579
    • Coenen, D. M., Heinzmann, A. C. A., Oggero, S., Albers, H. J., Nagy, M., Hague, P., Kuijpers, M. J. E., Vanderwinden, J. M., van der Meer, A. D., Perretti, M., Koenen, R. R., & Cosemans, J. M. E. M. (2021). Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions. Cells, 10(8), Article 1998. https://doi.org/10.3390/cells10081998
    • Willers, A., Arens, J., Mariani, S., Pels, H., Maessen, J. G., Hackeng, T. M., Lorusso, R., & Swol, J. (2021). New Trends, Advantages and Disadvantages in Anticoagulation and Coating Methods Used in Extracorporeal Life Support Devices. Membranes, 11(8), Article 617. https://doi.org/10.3390/membranes11080617
    • Ten Cate, H., Guzik, T. J., Eikelboom, J., & Spronk, H. M. H. (2021). Pleiotropic actions of factor Xa inhibition in cardiovascular prevention - mechanistic insights and implications for anti-thrombotic treatment. Cardiovascular Research, 117(9), 2030-2044. https://doi.org/10.1093/cvr/cvaa263
    • ten Cate, H., & Lammle, B. (2021). Special Issue: "The Latest Clinical Advances in Thrombocytopenia". Journal of Clinical Medicine, 10(16), Article 3463. https://doi.org/10.3390/jcm10163463
    • Aarsetøy, R., Ten Cate, H., Spronk, H., Van Oerle, R., Aarsetøy, H., Staines, H., & Nilsen, D. W. T. (2021). Activated factor XI-antithrombin complex presenting as an independent predictor of 30-days mortality in out-of-hospital cardiac arrest patients. Thrombosis Research, 204, 1-8. https://doi.org/10.1016/j.thromres.2021.05.014
    • Livneh, N., Braeken, D., Drozdinsky, G., Gafter-Gvili, A., Seelig, J., Rozovski, U., Berger, T., Raanani, P., Falanga, A., ten Cate, H., Spectre, G., & Leader, A. (2021). Anticoagulation in patients with atrial fibrillation, thrombocytopenia and hematological malignancy. Journal of Thrombosis and Thrombolysis, 52(2), 590-596. https://doi.org/10.1007/s11239-021-02393-8
    • Beldhuis, I. E., Marapin, R. S., Jiang, Y. Y., de Souza, N. F. S., Georgiou, A., Kaufmann, T., Forte, J. C., & van der Horst, I. C. C. (2021). Cognitive biases, environmental, patient and personal factors associated with critical care decision making: A scoping review. Journal of Critical Care, 64, 144-153. https://doi.org/10.1016/j.jcrc.2021.04.012
    • Kurniawati, E. R., Rutjens, V. G. H., Vranken, N. P. A., Delnoij, T. S. R., Lorusso, R., van der Horst, I. C. C., Maessen, J. G., & Weerwind, P. W. (2021). Quality of life following adult veno-venous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review. Quality of Life Research, 30(8), 2123-2135. https://doi.org/10.1007/s11136-021-02834-0
    • Dahlen, B., Schulz, A., Göbel, S., Tröbs, S.-O., Schwuchow-Thonke, S., Spronk, H. M., Prochaska, J. H., Arnold, N., Lackner, K. J., Gori, T., Ten Cate, H., Münzel, T., Wild, P. S., & Panova-Noeva, M. (2021). The impact of platelet indices on clinical outcome in heart failure: results from the MyoVasc study. Esc heart failure, 8(4), 2991-3001. https://doi.org/10.1002/ehf2.13390
    • Forte, C., Voinea, A., Chichirau, M., Yeshmagambetova, G., Albrecht, L. M., Erfurt, C., Freundt, L. A., Carmo, L. O. E., Henning, R. H., van der Horst, I. C. C., Sundelin, T., Wiering, M. A., Axelsson, J., & Epema, A. H. (2021). Deep Learning for Identification of Acute Illness and Facial Cues of Illness. Frontiers in medicine, 8, Article 661309. https://doi.org/10.3389/fmed.2021.661309
    • Vroomen, M., van Rosmalen, F., Schroeder, J., Philippens, S., Delhaas, T., Crijns, H. J., & Pison, L. (2021). Ten-year follow-up after endocardial point-by-point cryoablation for paroxysmal atrial fibrillation. Acta Cardiologica, 76(4), 425-430. https://doi.org/10.1080/00015385.2020.1756087
    • Barbateskovic, M., Koster, T. M., Eck, R. J., Maagaard, M., Afshari, A., Blokzijl, F., Cronhjort, M., Dieperink, W., Fabritius, M. L., Feinberg, J., French, C., Gareb, B., Geisler, A., Granholm, A., Hiemstra, B., Hu, R. X., Imberger, G., Jensen, B. T., Jonsson, A. B., ... Wetterslev, J. (2021). A new tool to assess Clinical Diversity In Meta-analyses (CDIM) of interventions. Journal of Clinical Epidemiology, 135, 29-41. https://doi.org/10.1016/j.jclinepi.2021.01.023
    • Bavalia, R., Bistervels, I. M., Boersma, W. G., Quere, I., Brisot, D., Falvo, N., Stephan, D., Couturaud, F., Schellong, S., Montaclair, K., Ghanima, W., ten Wolde, M., Coppens, M., Ferrari, E., Sanchez, O., Carroll, P., Kahn, S. R., Meijer, K., Birocchi, S., ... Hokusai Post-PE Study Investigator (2021). Quality of life in patients with pulmonary embolism treated with edoxaban versus warfarin. Research and practice in thrombosis and haemostasis, 5(5), Article e12566. https://doi.org/10.1002/rth2.12566
    • Driessen, R. G. H., Kiers, D., Schalkwijk, C. G., Scheijen, J. L. J. M., Gerretsen, J., Pickkers, P., van de Poll, M. C. G., van der Horst, I. C. C., Bergmans, D. C. J. J., Kox, M., & van Bussel, B. C. T. (2021). Systemic inflammation down-regulates glyoxalase-1 expression: an experimental study in healthy males. Bioscience Reports, 41(7), Article BSR20210954. https://doi.org/10.1042/BSR20210954
    • Lemkes, J. S., Spoormans, E. M., Demirkiran, A., Leutscher, S., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., Vlachojannis, G. J., Eikemans, B. J. W., van der Harst, P., van der Horst, I. C. C., Voskuil, M., ... van Royen, N. (2021). The effect of immediate coronary angiography after cardiac arrest without ST-segment elevation on left ventricular function. A sub-study of the COACT randomised trial. Resuscitation, 164, 93-100. https://doi.org/10.1016/j.resuscitation.2021.04.020
    • Camps, E. C., van Lith, S. A. M., Frielink, C., Lankhof, J., Dijkgraaf, I., Gotthardt, M., & Brock, R. (2021). CPPs to the Test: Effects on Binding, Uptake and Biodistribution of a Tumor Targeting Nanobody. Pharmaceuticals, 14(7), Article 602. https://doi.org/10.3390/ph14070602
    • Petersohn, S., Grimm, S. E., Ramaekers, B. L. T., ten Cate-Hoek, A. J., & Joore, M. A. (2021). Exploring the Feasibility of Comprehensive Uncertainty Assessment in Health Economic Modeling: A Case Study. Value in Health, 24(7), 983-994. https://doi.org/10.1016/j.jval.2021.01.004
    • Castoldi, E. (2021). F5-Atlanta: Factor V-short strikes again. Journal of Thrombosis and Haemostasis, 19(7), 1638-1640. https://doi.org/10.1111/jth.15351
    • Denisov, S. S., Ippel, J. H., Castoldi, E., Mans, B. J., Hackeng, T. M., & Dijkgraaf, I. (2021). Molecular basis of anticoagulant and anticomplement activity of the tick salivary protein Salp14 and its homologs. Journal of Biological Chemistry, 297(1), Article 100865. https://doi.org/10.1016/j.jbc.2021.100865
    • Herfs, L., Swieringa, F., Jooss, N., Kozlowski, M., Heubel-Moenen, F. C. J., van Oerle, R., Machiels, P., Henskens, Y., & Heemskerk, J. W. M. (2021). Multiparameter microfluidics assay of thrombus formation reveals increased sensitivity to contraction and antiplatelet agents at physiological temperature. Thrombosis Research, 203, 46-56. https://doi.org/10.1016/j.thromres.2021.04.014
    • Liu, X., Arfman, T., Wichapong, K., Reutelingsperger, C. P. M., Voorberg, J., & Nicolaes, G. A. F. (2021). PAD4 takes charge during neutrophil activation: Impact of PAD4 mediated NET formation on immune-mediated disease. Journal of Thrombosis and Haemostasis, 19(7), 1607-1617. https://doi.org/10.1111/jth.15313
    • Dickhout, A., Kaczor, D. M., Heinzmann, A. C. A., Brouns, S. L. N., Heemskerk, J. W. M., van Zandvoort, M. A. M. J., & Koenen, R. R. (2021). Rapid Internalization and Nuclear Translocation of CCL5 and CXCL4 in Endothelial Cells. International journal of molecular sciences, 22(14), Article 7332. https://doi.org/10.3390/ijms22147332
    • Stals, M. A. M., Kaptein, F. H. J., Bemelmans, R. H. H., van Bemmel, T., Boukema, I. C., Braeken, D. C. W., Braken, S. J. E., Bresser, C., Cate, H. T., Deenstra, D. D., Dooren, Y. P. A. V., Faber, L. M., Grootenboers, M. J. J. H., Haan, L. R. D., Haazer, C., Sol, A. I. D., Kelliher, S., Koster, T., Kroft, L. J. M., ... Dutch COVID & Thrombosis Coalition (DCTC) (2021). Ruling out Pulmonary Embolism in Patients with (Suspected) COVID-19-A Prospective Cohort Study. TH open : companion journal to thrombosis and haemostasis, 5(3), e387-e399. https://doi.org/10.1055/s-0041-1735155
    • Maag, A., Sharma, P., Schuijt, T. J., Kopatz, W. F., Kruijswijk, D., Marquart, J. A., van Der Poll, T., Hackeng, T. M., Nicolaes, G. A. F., Meijers, J. C. M., Bos, M. H. A., & van 't Veer, C. (2021). Structure-function of anticoagulant TIX-5, the inhibitor of factor Xa-mediated FV activation. Journal of Thrombosis and Haemostasis, 19(7), 1697-1708. https://doi.org/10.1111/jth.15329
    • Hisada, Y., Moser, B., Kawano, T., Revenko, A. S., Crosby, J. R., Spronk, H. M., & Mackman, N. (2021). The Intrinsic Pathway does not Contribute to Activation of Coagulation in Mice Bearing Human Pancreatic Tumors Expressing Tissue Factor. Thrombosis and Haemostasis, 121(07), 967-970. https://doi.org/10.1055/s-0040-1722193
    • Schol, P. B. B., de Lange, N. M., Woiski, M. D., Langenveld, J., Smits, L. J. M., Wassen, M. M., Henskens, Y. M., & Scheepers, H. C. J. (2021). Restrictive versus liberal fluid resuscitation strategy, influence on blood loss and hemostatic parameters in mild obstetric hemorrhage: An open-label randomized controlled trial. (REFILL study). PLOS ONE, 16(6), Article e0253765. https://doi.org/10.1371/journal.pone.0253765
    • van Doorn, W. P. T. M., Foreman, Y. D., Schaper, N. C., Savelberg, H. H. C. M., Koster, A., van der Kallen, C. J. H., Wesselius, A., Schram, M. T., Henry, R. M. A., Dagnelie, P. C., de Galan, B. E., Bekers, O., Stehouwer, C. D. A., Meex, S. J. R., & Brouwers, M. C. G. J. (2021). Machine learning-based glucose prediction with use of continuous glucose and physical activity monitoring data: The Maastricht Study. PLOS ONE, 16(6), Article 0253125. https://doi.org/10.1371/journal.pone.0253125
    • Baidildinova, G., Nagy, M., Jurk, K., Wild, P. S., ten Cate, H., & van der Meijden, P. E. J. (2021). Soluble Platelet Release Factors as Biomarkers for Cardiovascular Disease. Frontiers in Cardiovascular Medicine, 8, Article 684920. https://doi.org/10.3389/fcvm.2021.684920
    • Lacy, M., Buerger, C., Shami, A., Ahmadsei, M., Winkels, H., Nitz, K., van Tiel, C. M., Seijkens, T. T. P., Kusters, P. J. H., Karshovka, E., Prange, K. H. M., Wu, Y., Brouns, S. L. N., Unterlugauer, S., Kuijpers, M. J. E., Reiche, M. E., Steffens, S., Edsfeldt, A., Megens, R. T. A., ... Lutgens, E. (2021). Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease. Nature Communications, 12(1), Article 3754. https://doi.org/10.1038/s41467-021-23909-z
    • Donkers, M. A., Gilissen, V. J. H. S., Candel, M. J. J. M., van Dijk, N. M., Kling, H., Heijnen-Panis, R., Pragt, E., van der Horst, I., Pronk, S. A., & van Mook, W. N. K. A. (2021). Moral distress and ethical climate in intensive care medicine during COVID-19: a nationwide study. BMC Medical Ethics, 22(1), Article 73. https://doi.org/10.1186/s12910-021-00641-3
    • Slater, A., Di, Y., Clark, J. C., Jooss, N. J., Martin, E. M., Alenazy, F., Thomas, M. R., Ariens, R. A. S., Herr, A. B., Poulter, N. S., Emsley, J., & Watson, S. P. (2021). Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer. Blood, 137(24), 3443-3453. https://doi.org/10.1182/blood.2020009440
    • Dahlen, B., Mueller, F., Troebs, S.-O., Heidorn, M. W., Schulz, A., Arnold, N., Hermanns, M. I., Schwuchow-Thonke, S., Prochaska, J. H., Gori, T., ten Cate, H., Lackner, K. J., Muenzel, T., Wild, P. S., & Panova-Noeva, M. (2021). Sex-Specific Relationship Between Parathyroid Hormone and Platelet Indices in Phenotypes of Heart Failure - Results From the MyoVasc Study. Frontiers in Cardiovascular Medicine, 8, Article 682521. https://doi.org/10.3389/fcvm.2021.682521
    • Heijnen, N. F. L., Hagens, L. A., Smit, M. R., Cremer, O. L., Ong, D. S. Y., van der Poll, T., van Vught, L. A., Scicluna, B. P., Schnabel, R. M., van der Horst, I. C. C., Schultz, M. J., Bergmans, D. C. J. J., Bos, L. D. J., & MARD Consortium (2021). Biological Subphenotypes of Acute Respiratory Distress Syndrome Show Prognostic Enrichment in Mechanically Ventilated Patients without Acute Respiratory Distress Syndrome. American Journal of Respiratory and Critical Care Medicine, 203(12), 1503-1511. https://doi.org/10.1164/rccm.202006-2522OC
    • Cao, J., Balluff, B., Arts, M., Dubois, L. J., van Loon, L. J. C., Hackeng, T. M., van Eijk, H. M. H., Eijkel, G., Heij, L. R., Soons, Z., Olde Damink, S. W. M., & Heeren, R. M. A. (2021). Mass spectrometry imaging of L-[ring-13C6]-labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma. Cancer & Metabolism, 9(1), Article 26. https://doi.org/10.1186/s40170-021-00262-9
    • Ford, D. J., Duggan, N. M., Fry, S. E., Ripoll-Rozada, J., Agten, S. M., Liu, W., Corcilius, L., Hackeng, T. M., van Oerle, R., Spronk, H. M. H., Ashhurst, A. S., Mini Sasi, V., Kaczmarski, J. A., Jackson, C. J., Pereira, P. J. B., Passioura, T., Suga, H., & Payne, R. J. (2021). Potent Cyclic Peptide Inhibitors of FXIIa Discovered by mRNA Display with Genetic Code Reprogramming. Journal of Medicinal Chemistry, 64(11), 7853-7876. https://doi.org/10.1021/acs.jmedchem.1c00651
    • de Breet, C. P. D. M., Zwaveling, S., Vries, M. J. A., van Oerle, R. G., Henskens, Y. M. C., Van't Hof, A. W. J., van der Meijden, P. E. J., Veenstra, L., ten Cate, H., & Olie, R. H. (2021). Thrombin Generation as a Method to Identify the Risk of Bleeding in High Clinical-Risk Patients Using Dual Antiplatelet Therapy. Frontiers in Cardiovascular Medicine, 8, Article 679934. https://doi.org/10.3389/fcvm.2021.679934
    • Forte, J. C., Yeshmagambetova, G., van der Grinten, M. L., Hiemstra, B., Kaufmann, T., Eck, R. J., Keus, F., Epema, A. H., Wiering, M. A., & van der Horst, I. C. C. (2021). Identifying and characterizing high-risk clusters in a heterogeneous ICU population with deep embedded clustering. Scientific Reports, 11(1), Article 12109. https://doi.org/10.1038/s41598-021-91297-x
    • Notten, P., de Smet, A. A. E. A., Tick, L. W., van de Poel, M. H. W., Wikkeling, O. R. M., Vleming, L.-J., Koster, A., Jie, K.-S. G., Jacobs, E. M. G., Ebben, H. P., Coppens, M., ten Cate, H., Wittens, C. H. A., & ten Cate-Hoek, A. J. (2021). CAVA (Ultrasound-Accelerated Catheter-Directed Thrombolysis on Preventing Post-Thrombotic Syndrome) Trial: Long-Term Follow-Up Results. Journal of the American Heart Association, 10(11), Article 018973. https://doi.org/10.1161/JAHA.120.018973
    • Blokzijl, F., Onrust, M., Dieperink, W., Keus, F., van der Horst, I. C. C., Paans, W., Mariani, M. A., & Reneman, M. F. (2021). Barriers That Obstruct Return to Work After Coronary Bypass Surgery: A Qualitative Study. Journal of Occupational Rehabilitation, 31(2), 316-322. https://doi.org/10.1007/s10926-020-09919-6
    • Driessen, R. G. H., Latten, B. G. H., Bergmans, D. C. J. J., Hulsewe, R. P. M. G., Holtkamp, J. W. M., van der Horst, I. C. C., Kubat, B., & Schnabel, R. M. (2021). Clinical diagnoses vs. autopsy findings in early deceased septic patients in the intensive care: a retrospective cohort study. Virchows Archiv, 478(6), 1173-1178. https://doi.org/10.1007/s00428-020-02984-5
    • Wasserloos, A., Thomassen, M. C. L. G. D., Costa, S. D., Zenclussen, A., Tchaikovski, V. E., Hackeng, T. M., Stickeler, E., & Tchaikovski, S. N. (2021). Effect of blood loss during caesarean section on coagulation parameters. Thrombosis Research, 202, 84-89. https://doi.org/10.1016/j.thromres.2021.03.010
    • Bosveld, M. H., van Doorn, D. P. C., Stassen, P. M., Westerman, D., Bergmans, D. C. J. J., van der Horst, I. C. C., & van Mook, W. N. K. A. (2021). Lessons learned: Contribution to healthcare by medical students during COVID-19. Journal of Critical Care, 63, 113-116. https://doi.org/10.1016/j.jcrc.2020.09.015
    • Iding, A. F. J., Witten, A., Isaacs, A., Castoldi, E., ten Cate, H., Stoll, M., & ten Cate-Hoek, A. J. (2021). Leukocyte gene expression in post-thrombotic syndrome. Thrombosis Research, 202, 40-42. https://doi.org/10.1016/j.thromres.2021.03.007
    • Sabrkhany, S., Kuijpers, M. J. E., Egbrink, M. G. A. O., & Griffioen, A. W. (2021). Platelets as messengers of early-stage cancer. Cancer and Metastasis Reviews, 40(2), 563-573. https://doi.org/10.1007/s10555-021-09956-4