• 2021
    • Sun, S. Y., Urbanus, R. T., ten Cate, H., de Groot, P. G., de Laat, B., Heemskerk, J. W. M., & Roest, M. (2021). Platelet Activation Mechanisms and Consequences of Immune Thrombocytopenia. Cells, 10(12), Article 3386. https://doi.org/10.3390/cells10123386
    • van Haaps, T. F. V., Collard, D., van Osch, F. H. M. V., Middeldorp, S., Coppens, M., de Kruif, M. D., Vlot, E. A., Douma, R. A., ten Cate, H., Juffermans, N. P., Gritters, N., Vlaar, A. P., Reidinga, A. C., Heuvelmans, M. A., Oudkerk, M., Buller, H. R., van den Bergh, J. P. W. V., Maas, A., Ten Wolde, M., ... Dutch COVID & Thrombosis Coalition (2021). Pre-admission anticoagulant therapy and mortality in hospitalized COVID-19 patients: A retrospective cohort study. Thrombosis Research, 208, 35-38. https://doi.org/10.1016/j.thromres.2021.10.006
    • Dofferhoff, A. S. M., Piscaer, I., Schurgers, L. J., Visser, M. P. J., van den Ouweland, J. M. W., de Jong, P. A., Gosens, R., Hackeng, T. M., van Daal, H., Lux, P., Maassen, C., Karssemeijer, E. G. A., Vermeer, C., Wouters, E. F. M., Kistemaker, L. E. M., Walk, J., & Janssen, R. (2021). Reduced Vitamin K Status as a Potentially Modifiable Risk Factor of Severe Coronavirus Disease 2019. Clinical Infectious Diseases, 73(11), E4039-E4046. https://doi.org/10.1093/cid/ciaa1258
    • von Hundelshausen, P., Wichapong, K., Gabius, H. J., & Mayo, K. H. (2021). The marriage of chemokines and galectins as functional heterodimers. Cellular and Molecular Life Sciences, 78(24), 8073-8095. https://doi.org/10.1007/s00018-021-04010-6
    • Amer, A. Y. A., Wouters, F., Vranken, J., Dreesen, P., Boer, D. D., van Rosmalen, F., van Bussel, B. C. T., Smit-Fun, V., Duflot, P., Guiot, J., van der Horst, I. C. C., Mesotten, D., Vandervoort, P., Aerts, J. M., & Vanrumste, B. (2021). Vital Signs Prediction for COVID-19 Patients in ICU. Sensors, 21(23), Article 8131. https://doi.org/10.3390/s21238131
    • Wan, J., Konings, J., de Laat, B., Hackeng, T. M., & Roest, M. (2021). Added Value of Blood Cells in Thrombin Generation Testing. Thrombosis and Haemostasis, 121(12), 1574-1587. https://doi.org/10.1055/a-1450-8300
    • D'Alessandro, E., Scaf, B., van Oerle, R., van Nieuwenhoven, F. A., van Hunnik, A., Verheule, S., Schotten, U., Ten Cate, H., & Spronk, H. M. H. (2021). Thrombin generation by calibrated automated thrombography in goat plasma: Optimization of an assay. Research and practice in thrombosis and haemostasis, 5(8), Article e12620. https://doi.org/10.1002/rth2.12620
    • Montague, S. J., Patel, P., Martin, E. M., Slater, A., Quintanilla, L. G., Perrella, G., Kardeby, C., Nagy, M., Mezzano, D., Mendes, P. M., & Watson, S. P. (2021). Platelet activation by charged ligands and nanoparticles: platelet glycoprotein receptors as pattern recognition receptors. Platelets, 32(8), 1018-1030. https://doi.org/10.1080/09537104.2021.1945571
    • Nguyen, U. C., Vernemmen, A. I. P., Segers, P., zur Hausen, A., Driessen, R. G. H., Pluijmen, M. J. H. M., & Bekkers, S. C. A. M. (2021). Case Report: An Unusual Cause for Recurrent Hemopericardium in a Patient With Dyspnea. Frontiers in Cardiovascular Medicine, 8, Article 755106. https://doi.org/10.3389/fcvm.2021.755106
    • Cox, E. G. M., Onrust, M., Vos, M. E., Paans, W., Dieperink, W., Koeze, J., van der Horst, I. C. C., Wiersema, R., SICS Study Group, & SOCCS Student Team (2021). The simple observational critical care studies: estimations by students, nurses, and physicians of in-hospital and 6-month mortality. Critical Care, 25(1), Article 393. https://doi.org/10.1186/s13054-021-03809-w
    • Bervoets, L., Ippel, J. H., Smolinska, A., van Best, N., Savelkoul, P. H. M., Mommers, M. A. H., & Penders, J. (2021). Practical and Robust NMR-Based Metabolic Phenotyping of Gut Health in Early Life. Journal of Proteome Research, 20(11), 5079-5087. https://doi.org/10.1021/acs.jproteome.1c00617
    • van der Bruggen, M. M., Kremers, B., van Oerle, R., van Oostenbrugge, R. J., & ten Cate, H. (2021). Potential value of the calibrated automated thrombogram in patients after a cerebral venous sinus thrombosis; an exploratory study. Thrombosis Journal, 19(1), Article 81. https://doi.org/10.1186/s12959-021-00335-1
    • Driessen, R. G. H., Groven, R. V. M., van Koll, J., Oudhuis, G. J., Posthouwer, D., van der Horst, I. C. C., Bergmans, D. C. J. J., & Schnabel, R. M. (2021). Appropriateness of empirical antibiotic therapy and added value of adjunctive gentamicin in patients with septic shock: a prospective cohort study in the ICU. Infectious Diseases, 53(11), 830-838. https://doi.org/10.1080/23744235.2021.1942543
    • D'Alessandro, E., Scaf, B., Munts, C., van Hunnik, A., Trevelyan, C. J., Verheule, S., Spronk, H. M. H., Turner, N. A., ten Cate, H., Schotten, U., & van Nieuwenhoven, F. A. (2021). Coagulation Factor Xa Induces Proinflammatory Responses in Cardiac Fibroblasts via Activation of Protease-Activated Receptor-1. Cells, 10(11), Article 2958. https://doi.org/10.3390/cells10112958
    • Gandhi, S., Witten, A., De Majo, F., Gilbers, M., Maessen, J., Schotten, U., de Windt, L. J., & Stoll, M. (2021). Evolutionarily conserved transcriptional landscape of the heart defining the chamber specific physiology. Genomics, 113(6), 3782-3792. https://doi.org/10.1016/j.ygeno.2021.09.002
    • van der Beelen, S. H. E., Agten, S. M., Suylen, D. P. L., Wichapong, K., Hrdinova, J., Mees, B. M. E., Spronk, H. M. H., & Hackeng, T. M. (2021). Letter: In response to a recent letter by Prior et al.Thrombosis Research, 207, 66-66. https://doi.org/10.1016/j.thromres.2021.06.017
    • Perrella, G., Nagy, M., Watson, S. P., & Heemskerk, J. W. M. (2021). Platelet GPVI (Glycoprotein VI) and Thrombotic Complications in the Venous System. Arteriosclerosis Thrombosis and Vascular Biology, 41(11), 2681-2692. https://doi.org/10.1161/ATVBAHA.121.316108
    • Tchaikovski, S. N., Thomassen, M. C. L. G. D., Stickeler, E., Bremme, K., & Rosing, J. (2021). Resistance to activated protein C and impaired TFPI activity in women with previous hormone-induced venous thromboembolism. Thrombosis Research, 207, 143-149. https://doi.org/10.1016/j.thromres.2021.09.018
    • Strauch, U., Florack, M. C. D. M., Jansen, J., van Bussel, B. C. T., Beckers, S. K., Habers, J., Winkens, B., van der Horst, I. C. C., van Mook, W. N. K. A., & Bergmans, D. C. J. J. (2021). The QUality of Interhospital Transportation in the Euregion Meuse-Rhine (QUIT-EMR) score: a cross-validation study. BMJ Open, 11(11), Article e051100. https://doi.org/10.1136/bmjopen-2021-051100
    • Schol, P. B. B., de Lange, N. M., Smits, L. J. M., Henskens, Y. M. C., & Scheepers, H. C. J. (2021). Thromboelastometry in daily obstetric practice: At what amount of blood loss do we find abnormal results? A retrospective clinical observational study. Thrombosis Research, 207, 140-142. https://doi.org/10.1016/j.thromres.2021.09.015
    • Bruggemann, R. A. G., Alnima, T., Brouns, S. H. A., Hanssen, N. M. J., Schols, J. M. G. A., ten Cate, H., Spaetgens, B., & ten Cate-Hoek, A. J. (2021). A known unknown? Pharmacological prevention of venous thromboembolism in nursing home residents. Journal of the American Geriatrics Society, 69(11), 3338-3343. https://doi.org/10.1111/jgs.17422
    • Jessurun, N. T., Drent, M., Wijnen, P. A., Harmsze, A. M., van Puijenbroek, E. P., Bekers, O., & Bast, A. (2021). Role of Drug-Gene Interactions and Pharmacogenetics in Simvastatin-Associated Pulmonary Toxicity. Drug Safety, 44(11), 1179-1191. https://doi.org/10.1007/s40264-021-01105-8
    • Prochaska, J. H., Arnold, N., Falcke, A., Kopp, S., Schulz, A., Buch, G., Moll, S., Panova-Noeva, M., Junger, C., Eggebrecht, L., Pfeiffer, N., Beutel, M., Binder, H., Grabbe, S., Lackner, K. J., Ten Cate-Hoek, A., Espinola-Klein, C., Munzel, T., & Wild, P. S. (2021). Chronic venous insufficiency, cardiovascular disease, and mortality: a population study. European Heart Journal, 42(40), 4157-4165. https://doi.org/10.1093/eurheartj/ehab495
    • Dowman, L. J., Agten, S., Ripoll-Rozada, J., Calisto, B., Pereira, P. J. B., & Payne, R. J. (2021). Synthesis and evaluation of peptidic thrombin inhibitors bearing acid-stable sulfotyrosine analogues. Chemical Communications, 57(83), 10923-10926. https://doi.org/10.1039/d1cc04742f
    • Martens, L., Ruehle, F., Witten, A., Meder, B., Katus, H. A., Arbustini, E., Hasenfuss, G., Sinner, M. F., Kaeaeb, S., Pankuweit, S., Angermann, C., Bornberg-Bauer, E., & Stoll, M. (2021). A genetic variant alters the secondary structure of the lncRNA H19 and is associated with dilated cardiomyopathy. Rna Biology, 18, 409-415. https://doi.org/10.1080/15476286.2021.1952756
    • Tas, J., Beqiri, E., van Kaam, R. C., Czosnyka, M., Donnelly, J., Haeren, R. H., van der Horst, I. C. C., Hutchinson, P. J., van Kuijk, S. M. J., Liberti, A. L., Menon, D. K., Hoedemaekers, C. W. E., Depreitere, B., Smielewski, P., Meyfroidt, G., Ercole, A., & Aries, M. J. H. (2021). Targeting Autoregulation-Guided Cerebral Perfusion Pressure after Traumatic Brain Injury (COGiTATE): A Feasibility Randomized Controlled Clinical Trial. Journal of Neurotrauma, 38(20), 2790-2800. https://doi.org/10.1089/neu.2021.0197
    • Denisov, S. S., & Dijkgraaf, I. (2021). Immunomodulatory Proteins in Tick Saliva From a Structural Perspective. Frontiers in Cellular and Infection Microbiology, 11, Article 769574. https://doi.org/10.3389/fcimb.2021.769574
    • Klinkhammer, S., Horn, J., Visser-Meilij, J. M. A., Verwijk, E., Duits, A., Slooter, A. J. C., van Heugten, C. M., NeNeSCo study group, Aries, M., van Bussel, B., Janssen, M., Postma - Jacobi, L., & van Santen, S. (2021). Dutch multicentre, prospective follow-up, cohort study comparing the neurological and neuropsychological sequelae of hospitalised non-ICU- and ICU-treated COVID-19 survivors: a study protocol. BMJ Open, 11(10), Article e054901. https://doi.org/10.1136/bmjopen-2021-054901
    • Fernandez, D. I., Kuijpers, M. J. E., & Heemskerk, J. W. M. (2021). Platelet calcium signaling by G-protein coupled and ITAM-linked receptors regulating anoctamin-6 and procoagulant activity. Platelets, 32(7), 863-871. https://doi.org/10.1080/09537104.2020.1859103
    • Ho, L. T. S., McVey, M. J., Kuiper, G. J. A. J. M., Gross, P. L., & Karkouti, K. (2021). Analysis of the effect of varying protamine-to-heparin ratio on coagulation in vitro. British Journal of Anaesthesia, 127(4), E128-E130. https://doi.org/10.1016/j.bja.2021.06.037
    • Todaro, A. M., Hackeng, T. M., & Castoldi, E. (2021). Antisense-Mediated Down-Regulation of Factor V-Short Splicing in a Liver Cell Line Model. Applied Sciences, 11(20), Article 9621. https://doi.org/10.3390/app11209621
    • Ercig, B., Arfman, T., Hrdinova, J., Wichapong, K., Reutelingsperger, C. P. M., Vanhoorelbeke, K., Nicolaes, G. A. F., & Voorberg, J. (2021). Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity. Journal of Biological Chemistry, 297(4), Article 101132. https://doi.org/10.1016/j.jbc.2021.101132
    • van Gassel, R. J. J., Bels, J., Remij, L., van Bussel, B. C. T., Posthuma, R., Gietema, H. A., Verbunt, J., van der Horst, I. C. C., Damink, S. W. M. O., van Santen, S., & van de Poll, M. C. G. (2021). Functional Outcomes and Their Association With Physical Performance in Mechanically Ventilated Coronavirus Disease 2019 Survivors at 3 Months Following Hospital Discharge: A Cohort Study. Critical Care Medicine, 49(10), 1726-1738. https://doi.org/10.1097/CCM.0000000000005089
    • Gijs, M., Veugen, J. M. J., Wolffs, P. F. G., Savelkoul, P. H. M., Tas, J., van Bussel, B. C. T., de Kruif, M. D., Henry, R. M. A., Webers, C. A. B., Dickman, M. M., & Nuijts, R. M. M. A. (2021). In-Depth Investigation of Conjunctival Swabs and Tear Fluid of Symptomatic COVID-19 Patients, an Observational Cohort Study. Translational Vision Science & Technology, 10(12), Article 32. https://doi.org/10.1167/tvst.10.12.32
    • Tullemans, B. M. E., Veninga, A., Fernandez, D. I., Aarts, M. J. B., Eble, J. A., van der Meijden, P. E. J., Heemskerk, J. W. M., & Kuijpers, M. J. E. (2021). Multiparameter Evaluation of the Platelet-Inhibitory Effects of Tyrosine Kinase Inhibitors Used for Cancer Treatment. International Journal of Molecular Sciences, 22(20), Article 11199. https://doi.org/10.3390/ijms222011199
    • Kimenai, D. M., Shah, A. S. V., McAllister, D. A., Lee, K. K., Tsanas, A., Meex, S. J. R., Porteous, D. J., Hayward, C., Campbell, A., Sattar, N., Mills, N. L., & Welsh, P. (2021). Sex Differences in Cardiac Troponin I and T and the Prediction of Cardiovascular Events in the General Population. Clinical Chemistry, 67(10), 1351-1360. https://doi.org/10.1093/clinchem/hvab109
    • Jiritano, F., Fina, D., Lorusso, R., ten Cate, H., Kowalewski, M., Matteucci, M., Serra, R., Mastroroberto, P., & Serraino, G. F. (2021). Systematic review and meta-analysis of the clinical effectiveness of point-of-care testing for anticoagulation management during ECMO. Journal of Clinical Anesthesia, 73, Article 110330. https://doi.org/10.1016/j.jclinane.2021.110330
    • Schreurs, R. H. P., Joore, M. A., ten Cate, H., & ten Cate-Hoek, A. J. (2021). Using the Functional Resonance Analysis Method to explore how elastic compression therapy is organised and could be improved from a multistakeholder perspective. BMJ Open, 11(10), Article e048331. https://doi.org/10.1136/bmjopen-2020-048331
    • Olie, R. H., van der Meijden, P. E. J., Vries, M. J. A., Veenstra, L., van't Hof, A. W. J., ten Berg, J. M., Henskens, Y. M. C., & ten Cate, H. (2021). Antithrombotic therapy in high-risk patients after percutaneous coronary intervention; study design, cohort profile and incidence of adverse events. Netherlands Heart Journal, 29(10), 525-535. https://doi.org/10.1007/s12471-021-01606-2
    • Heinzmann, A. C. A., Coenen, D. M., Vajen, T., Cosemans, J. M. E. M., & Koenen, R. R. (2021). Combined Antiplatelet Therapy Reduces the Proinflammatory Properties of Activated Platelets. TH open : companion journal to thrombosis and haemostasis, 5(4), e533-e542. https://doi.org/10.1055/a-1682-3415
    • Slikkerveer, M., van de Plas, A., Driessen, J. H. M., Wijngaard, R., de Vries, F., Olie, R., Meertens, N., & van den Bemt, P. (2021). Prescribing Errors With Low-Molecular-Weight Heparins. Journal of Patient Safety, 17(7), e587-e592. https://doi.org/10.1097/PTS.0000000000000417
    • Boekel, M. F., Venema, C. S., Kaufmann, T., van der Horst, I. C. C., Vos, J. J., & Scheeren, T. W. L. (2021). The effect of compliance with a perioperative goal-directed therapy protocol on outcomes after high-risk surgery: a before-after study. Journal of Clinical Monitoring and Computing, 35(5), 1193-1202. https://doi.org/10.1007/s10877-020-00585-w
    • Huckriede, J., de Vries, F., Hultstroem, M., Wichapong, K., Reutelingsperger, C., Lipcsey, M., de Frutos, P. G., Frithiof, R., & Nicolaes, G. A. F. (2021). Histone H3 Cleavage in Severe COVID-19 ICU Patients. Frontiers in Cellular and Infection Microbiology, 11, Article 694186. https://doi.org/10.3389/fcimb.2021.694186
    • De Majo, F., Martens, L., Hegenbarth, J. C., Ruhle, F., Hamczyk, M. R., Nevado, R. M., Andres, V., Hilbold, E., Bar, C., Thum, T., de Boer, M., Duncker, D. J., Schroen, B., Armand, A. S., Stoll, M., & De Windt, L. J. (2021). Genomic instability in the naturally and prematurely aged myocardium. Proceedings of the National Academy of Sciences of the United States of America, 118(36), Article e2022974118. https://doi.org/10.1073/pnas.2022974118
    • Linz, D., Verheule, S., Isaacs, A., & Schotten, U. (2021). Considerations for the Assessment of Substrates, Genetics and Risk Factors in Patients with Atrial Fibrillation. Arrhythmia & Electrophysiology Review, 10(3), 132-139. https://doi.org/10.15420/aer.2020.51
    • Olie, R. H., Hensgens, R. R. K., Wijnen, P. A. H. M., Veenstra, L. F., de Greef, B. T. A., Vries, M. J. A., van der Meijden, P. E. J., ten Berg, J. M., ten Cate, H., Bekers, O., & Henskens, Y. M. C. (2021). Differential Impact of Cytochrome 2C19 Allelic Variants on Three Different Platelet Function Tests in Clopidogrel-Treated Patients. Journal of Clinical Medicine, 10(17), Article 3992. https://doi.org/10.3390/jcm10173992
    • Kimenai, D. M., Lindahl, B., Chapman, A. R., Baron, T., Gard, A., Wereski, R., Meex, S. J. R., Jernberg, T., Mills, N. L., & Eggers, K. M. (2021). Sex differences in investigations and outcomes among patients with type 2 myocardial infarction. Heart, 107(18), 1480-1486. https://doi.org/10.1136/heartjnl-2021-319118
    • D'Ambrosi, S., Visser, A., Antunes-Ferreira, M., Poutsma, A., Giannoukakos, S., Sol, N., Sabrkhany, S., Bahce, I., Kuijpers, M. J. E., Egbrink, M. G. A. O., Griffioen, A. W., Best, M. G., Koppers-Lalic, D., Oudejans, C., & Wurdinger, T. (2021). The Analysis of Platelet-Derived circRNA Repertoire as Potential Diagnostic Biomarker for Non-Small Cell Lung Cancer. Cancers, 13(18), Article 4644. https://doi.org/10.3390/cancers13184644
    • Heuts, S., Ubben, J. F., Banks-Gonzales, V., Sels, J.-W., Lorusso, R., van Mook, W. N. K. A., & Delnoij, T. S. R. (2021). Nitric Oxide Ventilation Improves Recirculation and Right Ventricular Function During Veno-Venous Extracorporeal Membrane Oxygenation in a COVID-19 Patient. Journal of Cardiothoracic and Vascular Anesthesia, 35(9), 2763-2767. https://doi.org/10.1053/j.jvca.2020.09.137