Marleen van Greevenbroek

Associate professor

Dr Marleen van Greevenbroek is Medical Biologist (University of Utrecht, 1992) and Epidemiologist (Maastricht University, 2012). She received her PhD degree in 1997 at the University of Utrecht, on a thesis concerning the effects of fatty acids on the production of intestinal triglyceride-rich lipoproteins. In September 1997, she was appointed at the University of Maastricht (Dept. of Internal Medicine), where she was involved in studies on the metabolic and genetic aspects of obesity and cardiometabolic diseases.

Her main area of research is the identification of early events in the development of insulin resistance, type 2 diabetes, and cardiovascular disease. In recent years, her research activities specifically focused on the role of the complement system herein. This research encompasses both cohort studies and experimental work.

 

Department of Internal Medicine
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

  • 2017
    • Mandaviya, P. R., Aissi, D., Dekkers, K. F., Joehanes, R., Kasela, S., Vinh Truong, Stolk, L., van Heemst, D., Ikram, M. A., Lindemans, J., Slagboom, P. E., Tregouet, D.-A., Uitterlinden, A. G., Wei, C., Wells, P., Gagnon, F., van Greevenbroek, M. M. J., Heijmans, B. T., Milani, L., ... BIOS Consortium (2017). Homocysteine levels associate with subtle changes in leukocyte DNA methylation: an epigenome-wide analysis. Epigenomics, 9(11), 1403-1422. https://doi.org/10.2217/epi-2017-0038
    • Mandaviya, P. R., Joehanes, R., Aissi, D., Kuehnel, B., Marioni, R. E., Truong, V., Stolk, L., Beekman, M., Bonder, M. J., Franke, L., Gieger, C., Huan, T., Ikram, M. A., Kunze, S., Liang, L., Lindemann, J., Liu, C., McRae, A. F., Mendelson, M. M., ... Charge Consortium Epigenetics Grp (2017). Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes. PLOS ONE, 12(10), Article 0182472. https://doi.org/10.1371/journal.pone.0182472
    • van Moorsel, D., Henry, R. M., Schaper, N. C., van Greevenbroek, M. M., van Rossum, E. F., 't Hart, L. M., Schalkwijk, C. G., van der Kallen, C. J., Dekker, J. M., Stehouwer, C. D., & Havekes, B. (2017). BclI Glucocorticoid Receptor Polymorphism in Relation to Arterial Stiffening and Cardiac Structure and Function: The Hoorn and CODAM Studies. American Journal of Hypertension, 30(3), 286-294. https://doi.org/10.1093/ajh/hpw196
    • den Biggelaar, L. J. C. J., Sep, S. J. S., Eussen, S. J. P. M., Mari, A., Ferrannini, E., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., & Dagnelie, P. C. (2017). Discriminatory ability of simple OGTT-based beta cell function indices for prediction of prediabetes and type 2 diabetes: the CODAM study. Diabetologia, 60(3), 432-441. https://doi.org/10.1007/s00125-016-4165-3
    • Wouters, K., Gaens, K., Bijnen, M., Verboven, K., Jocken, J., Wetzels, S., Wijnands, E., Hansen, D., van Greevenbroek, M., Duijvestijn, A. M., Biessen, E. A. L., Blaak, E. E., Stehouwer, C. D. A., & Schalkwijk, C. G. (2017). Circulating classical monocytes are associated with CD11c(+) macrophages in human visceral adipose tissue. Scientific Reports, 7, Article 42665. https://doi.org/10.1038/srep42665
    • van Iterson, M., van Zwet, E. W., Heijmans, B. T., 't Hoen, P. A. C., van Meurs, J., Jansen, R., Franke, L., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., van Greevenbroek, M. M. J., Stehouwer, C. D. A., van der Kallen, C. J. H., Schalkwijk, C. G., Wijmenga, C., Zhernakova, S., Tigchelaar, E. F., Eline Slagboom, P., ... BIOS Consortium (2017). Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution. Genome Biology, 18(1), Article 19. https://doi.org/10.1186/s13059-016-1131-9
    • Bonder, M. J., Luijk, R., Zhernakova, D. V., Moed, M., Deelen, P., Vermaat, M., van Iterson, M., van Dijk, F., van Galen, M., Bot, J., Slieker, R. C., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., van Rooij, J., Lakenberg, N., Arindrarto, W., ... Franke, L. (2017). Disease variants alter transcription factor levels and methylation of their binding sites. Nature Genetics, 49(1), 131-138. https://doi.org/10.1038/ng.3721
    • Zhernakova, D. V., Deelen, P., Vermaat, M., van Iterson, M., van Galen, M., Arindrarto, W., van 't Hof, P., Mei, H., van Dijk, F., Westra, H.-J., Bonder, M. J., van Rooij, J., Verkerk, M., Jhamai, P. M., Moed, M., Kielbasa, S. M., Bot, J., Nooren, I., Pool, R., ... Franke, L. (2017). Identification of context-dependent expression quantitative trait loci in whole blood. Nature Genetics, 49(1), 139-145. https://doi.org/10.1038/ng.3737
  • 2016
    • Simons, N., Dekker, J. M., van Greevenbroek, M. M. J., Nijpels, G., 't Hart, L. M., van der Kallen, C. J. H., Schalkwijk, C. G., Schaper, N. C., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2016). A Common Gene Variant in Glucokinase Regulatory Protein Interacts With Glucose Metabolism on Diabetic Dyslipidemia: the Combined CODAM and Hoorn Studies. Diabetes Care, 39(10), 1811-1817. https://doi.org/10.2337/dc16-0153
    • Slieker, R. C., van Iterson, M., Luijk, R., Beekman, M., Zhernakova, D. V., Moed, M. H., Mei, H., van Galen, M., Deelen, P., Bonder, M. J., Zhernakova, A., Uitterlinden, A. G., Tigchelaar, E. F., Stehouwer, C. D. A., Schalkwijk, C. G., van der Kallen, C. J. H., Hofman, A., van Heemst, D., de Geus, E. J., ... Heijmans, B. T. (2016). Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms. Genome Biology (Online), 17(1), Article 191. https://doi.org/10.1186/s13059-016-1053-6
    • Dekkers, K. F., van Iterson, M., Slieker, R. C., Moed, M. H., Bonder, M. J., van Galen, M., Mei, H., Zhernakova, D. V., van den Berg, L. H., Deelen, J., van Dongen, J., van Heemst, D., Hofman, A., Hottenga, J. J., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., Tigchelaar, E. F., Uitterlinden, A. G., ... Heijmans, B. T. (2016). Blood lipids influence DNA methylation in circulating cells. Genome Biology (Online), 17(1), Article 135. https://doi.org/10.1186/s13059-016-1000-6
    • Wanders, A. J., Alssema, M., van Greevenbroek, M. J., Elshorbagy, A., Zock, P. L., Dekker, J. M., & Brouwer, I. A. (2016). Comment on Sergeant et al.: Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans. British Journal of Nutrition, 115(11), 2077-2078. https://doi.org/10.1017/S0007114516000933
    • Annema, W., Dikkers, A., de Boer, J. F., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., Dullaart, R. P. F., & Tietge, U. J. F. (2016). Impaired HDL cholesterol efflux in metabolic syndrome is unrelated to glucose tolerance status: the CODAM study. Scientific Reports, 6, Article 27367. https://doi.org/10.1038/srep27367
    • Hertle, E., Arts, I. C. W., van der Kallen, C. J. H., Feskens, E. J. M., Schalkwijk, C. G., Hoffmann-Petersen, I. T., Thiel, S., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2016). Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima-Media Thickness The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study. Arteriosclerosis Thrombosis and Vascular Biology, 36(6), 1278-1285. https://doi.org/10.1161/ATVBAHA.115.306552
    • BIOS Consortium, van Greevenbroek, M., Stehouwer, C., van der Kallen, C. J. H., & Schalkwijk, C. (2016). Genetic and environmental influences interact with age and sex in shaping the human methylome. Nature Communications, 7, Article 11115. https://doi.org/10.1038/ncomms11115
    • Hertle, E., Arts, I. C. W., van der Kallen, C. J. H., Feskens, E. J. M., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2016). The alternative complement pathway is longitudinally associated with adverse cardiovascular outcomes The CODAM study. Thrombosis and Haemostasis, 115(2), 446-457. https://doi.org/10.1160/TH15-05-0439
    • van Greevenbroek, M. M. J., Schalkwijk, C. G., & Stehouwer, C. D. A. (2016). Dysfunctional adipose tissue and low-grade inflammation in the management of the metabolic syndrome: current practices and future advances. F1000Research, 5, Article 2515. https://doi.org/10.12688/f1000research.8971.1
  • 2015
    • Gaens, K. H. J., Ferreira, I., van de Waarenburg, M. P. H., van Greevenbroek, M. M., van der Kallen, C. J. H., Dekker, J. M., Nijpels, G., Rensen, S. S., Stehouwer, C. D. A., & Schalkwijk, C. G. (2015). Protein-Bound Plasma N-epsilon-(Carboxymethyl) lysine Is Inversely Associated With Central Obesity and Inflammation and Significantly Explain a Part of the Central Obesity-Related Increase in Inflammation The Hoorn and CODAM Studies. Arteriosclerosis Thrombosis and Vascular Biology, 35(12), 2707-2713. https://doi.org/10.1161/ATVBAHA.115.306106
    • Maessen, D. E., Hanssen, N. M., Scheijen, J. L., van der Kallen, C. J., van Greevenbroek, M. M., Stehouwer, C. D., & Schalkwijk, C. G. (2015). Post-Glucose Load Plasma alpha-Dicarbonyl Concentrations Are Increased in Individuals With Impaired Glucose Metabolism and Type 2 Diabetes: The CODAM Study. Diabetes Care, 38(5), 913-920. https://doi.org/10.2337/dc14-2605
    • Wlazlo, N., van Greevenbroek, M. M. J., Ferreira, I., Jansen, E. H. J. M., Feskens, E. J. M., van der Kallen, C. J. H., Schalkwijk, C. G., Bravenboer, B., & Stehouwer, C. D. A. (2015). Iron metabolism is prospectively associated with insulin resistance and glucose intolerance over a 7-year follow-up period: the CODAM study. Acta Diabetologica, 52(2), 337-348. https://doi.org/10.1007/s00592-014-0646-3
    • van Bussel, B. C. T., Henry, R. M. A., Ferreira, I., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Twisk, J. W. R., Feskens, E. J. M., Schalkwijk, C. G., & Stehouwer, C. D. A. (2015). A Healthy Diet is Associated with Less Endothelial Dysfunction and Less Low-Grade Inflammation over a 7-Year Period in Adults at Risk of Cardiovascular Disease. Journal of Nutrition, 145(3), 532-540. https://doi.org/10.3945/jn.114.201236
    • van Moorsel, D., van Greevenbroek, M. M. J., Schaper, N. C., Henry, R. M. A., Geelen, C. C., van Rossum, E. F. C., Nijpels, G., 't Hart, L. M., Schalkwijk, C. G., van der Kallen, C. J. H., Sauerwein, H. P., Dekker, J. M., Stehouwer, C. D. A., & Havekes, B. (2015). BclI glucocorticoid receptor polymorphism in relation to cardiovascular variables: the Hoorn and CODAM studies. European Journal of Endocrinology, 173(4), 455-464. https://doi.org/10.1530/EJE-15-0381
  • 2014
    • Herbert, A., Cruickshank, J. K., Laurent, S., The Reference Values for Arterial Measurements Collaboration, Stehouwer, C., Ferreira, I., Schalkwijk, C., van Greevenbroek, M., van der Kallen, C., van de Laar, R., Staessen, J., & Boutouyrie, P. (2014). Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors. European Heart Journal, 35(44), 3122–3133. https://doi.org/10.1093/eurheartj/ehu293
    • Wijnands, J. M. A., Boonen, A., Dagnelie, P. C., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Ferreira, I., Schalkwijk, C. G., Feskens, E. J. M., Stehouwer, C. D. A., van der Linden, S., & Arts, I. C. W. (2014). The cross-sectional association between uric acid and atherosclerosis and the role of low-grade inflammation: the CODAM study. Rheumatology, 53(11), 2053-2062. https://doi.org/10.1093/rheumatology/keu239
    • Hertle, E., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2014). The complement system in human cardiometabolic disease. Molecular Immunology, 61(2), 135-148. https://doi.org/10.1016/j.molimm.2014.06.031
    • Wlazlo, N., van Greevenbroek, M. M. J., Ferreira, I., Feskens, E. J. M., van der Kallen, C. J. H., Schalkwijk, C. G., Bravenboer, B., & Stehouwer, C. D. A. (2014). Complement Factor 3 Is Associated With Insulin Resistance and With Incident Type 2 Diabetes Over a 7-Year Follow-up Period: The CODAM Study. Diabetes Care, 37(7), 1900-1909. https://doi.org/10.2337/dc13-2804
    • Hertle, E., van Greevenbroek, M. M., Arts, I. C., van der Kallen, C. J., Geijselaers, S. L., Feskens, E. J., Jansen, E. H., Schalkwijk, C. G., & Stehouwer, C. D. (2014). Distinct associations of complement C3a and its precursor C3 with atherosclerosis and cardiovascular disease The CODAM study. Thrombosis and Haemostasis, 111(6), 1102-1111. https://doi.org/10.1160/TH13-10-0831
    • van Greevenbroek, M. M. J., Stalenhoef, A. F. H., de Graaf, J., & Brouwers, M. C. G. J. (2014). Familial combined hyperlipidemia: from molecular insights to tailored therapy. Current Opinion in Lipidology, 25(3), 176-182. https://doi.org/10.1097/MOL.0000000000000068
    • Brouwers, M. C. G. J., van Greevenbroek, M. M. J., Konrad, R. J., Troutt, J. S., Schaper, N. C., & Stehouwer, C. D. A. (2014). Circulating PCSK9 is a strong determinant of plasma triacylglycerols and total cholesterol in homozygous carriers of apolipoprotein ε2. Clinical Science, 126(9), 679-684. https://doi.org/10.1042/CS20130556
    • Vaarhorst, A. A. M., Verhoeven, A., Weller, C. M., Böhringer, S., Göraler, S., Meissner, A., Deelder, A. M., Henneman, P., Gorgels, A. P. M., van den Brandt, P. A., Schouten, L. J., van Greevenbroek, M. M., Merry, A. H. H., Verschuren, W. M. M., van den Maagdenberg, A. M. J. M., van Dijk, K. W., Isaacs, A., Boomsma, D., Oostra, B. A., ... Slagboom, P. E. (2014). A metabolomic profile is associated with the risk of incident coronary heart disease. American Heart Journal, 168(1), 45-52.e7. https://doi.org/10.1016/j.ahj.2014.01.019
    • Hertle, E., van Greevenbroek, M. M. J., Arts, I. C. W., van der Kallen, C. J. H., Feskens, E. J. M., Schalkwijk, C. G., & Stehouwer, C. D. A. (2014). Complement activation products C5a and sC5b-9 are associated with low-grade inflammation and endothelial dysfunction, but not with atherosclerosis in a cross-sectional analysis: The CODAM study. International Journal of Cardiology, 174(2), 400-403. https://doi.org/10.1016/j.ijcard.2014.04.057
    • van Greevenbroek, M. M. J., Arts, I. C. W., van der Kallen, C. J. H., Dagnelie, P. C., Ferreira, I., Jansen, E., Schalkwijk, C. G., Feskens, E. J. M., & Stehouwer, C. D. A. (2014). Complement C3 Is Inversely Associated with Habitual Intake of Provitamin A but Not with Dietary Fat, Fatty Acids, or Vitamin E in Middle-Aged to Older White Adults and Positively Associated with Intake of Retinol in Middle-Aged to Older White Women. Journal of Nutrition, 144(1), 61-67. https://doi.org/10.3945/jn.113.181628
    • Gaens, K. H., Goossens, G. H., Niessen, P. M., van Greevenbroek, M. M., van der Kallen, C. J., Niessen, H. W., Rensen, S. S., Buurman, W. A., Greve, J. W., Blaak, E. E., van Zandvoort, M. A., Bierhaus, A., Stehouwer, C. D., & Schalkwijk, C. G. (2014). Nε-(Carboxymethyl)lysine-Receptor for Advanced Glycation End Product Axis Is a Key Modulator of Obesity-Induced Dysregulation of Adipokine Expression and Insulin Resistance. Arteriosclerosis Thrombosis and Vascular Biology, 34(6), 1199-1208. https://doi.org/10.1161/ATVBAHA.113.302281
  • 2013
    • van Woudenbergh, G. J., Theofylaktopoulou, D., Kuijsten, A., Ferreira, I., van Greevenbroek, M. M., van der Kallen, C. J., Schalkwijk, C. G., Stehouwer, C. D., Ocke, M. C., Nijpels, G., Dekker, J. M., Blaak, E. E., & Feskens, E. J. (2013). Adapted dietary inflammatory index and its association with a summary score for low-grade inflammation and markers of glucose metabolism: the Cohort study on Diabetes and Atherosclerosis Maastricht (CODAM) and the Hoorn study.American Journal of Clinical Nutrition, 98(6), 1533-1542. https://doi.org/10.3945/ajcn.112.056333
    • Brouwers, M. C. G. J., Konrad, R. J., van Himbergen, T. M., Isaacs, A., Otokozawa, S., Troutt, J. S., Schaefer, E. J., van Greevenbroek, M. M. J., Stalenhoef, A. F. H., & de Graaf, J. (2013). Plasma proprotein convertase subtilisin kexin type 9 levels are related to markers of cholesterol synthesis in familial combined hyperlipidemia. Nutrition Metabolism and Cardiovascular Diseases, 23(11), 1115-1121. https://doi.org/10.1016/j.numecd.2012.11.008
    • Wlazlo, N., van Greevenbroek, M. M., Curvers, J., Schoon, E. J., Friederich, P., Twisk, J. W. R., Bravenboer, B., & Stehouwer, C. D. A. (2013). Diabetes mellitus at the time of diagnosis of cirrhosis is associated with higher incidence of spontaneous bacterial peritonitis, but not with increased mortality. Clinical Science, 125(7-8), 341-348. https://doi.org/10.1042/CS20120596
    • Hanssen, N. M. J., Engelen, L., Ferreira, I., Scheijen, J. L. J. M., Huijberts, M. S., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Dekker, J. M., Nijpels, G., Stehouwer, C. D. A., & Schalkwijk, C. G. (2013). Plasma Levels of Advanced Glycation Endproducts N-is an element of-(carboxymethyl)lysine, N-is an element of-(carboxyethyl)lysine, and Pentosidine Are not Independently Associated With Cardiovascular Disease in Individuals With or Without Type 2 Diabetes: The Hoorn and CODAM Studies. Journal of Clinical Endocrinology & Metabolism, 98(8), E1369-E1373. https://doi.org/10.1210/jc.2013-1068
    • Reference Values for Arterial Measurements Collaboration, Schalkwijk, C., van Greevenbroek, M., van der Kallen, C., van de Laar, R., Staessen, J., Vermeer, C., Braam, L., & Knapen, M. H. J. (2013). Reference intervals for common carotid intima-media thickness measured with echotracking: relation with risk factors. European Heart Journal, 34(30), 2368-U30. https://doi.org/10.1093/eurheartj/ehs380
    • Wlazlo, N., van Greevenbroek, M. M. J., Ferreira, I., Jansen, E. H. J. M., Feskens, E. J. M., van der Kallen, C. J. H., Schalkwijk, C. G., Bravenboer, B., & Stehouwer, C. D. A. (2013). Activated complement factor 3 is associated with liver fat and liver enzymes: the CODAM study. European Journal of Clinical Investigation, 43(7), 679-688. https://doi.org/10.1111/eci.12093
    • van Greevenbroek, M. M. J., Schalkwijk, C. G., & Stehouwer, C. D. A. (2013). Obesity-associated low-grade inflammation in type 2 diabetes mellitus: causes and consequences. Netherlands Journal of Medicine, 71(4), 174-187.
    • van Bussel, B. C. T., Ferreira, I., van de Waarenburg, M. P., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Henry, R. M., Feskens, E. J., Stehouwer, C. D. A., & Schalkwijk, C. G. (2013). Multiple inflammatory biomarker detection in a prospective cohort study: a cross-validation between well-established single-biomarker techniques and an electrochemiluminescense-based multi-array platform.PLOS ONE, 8(3), Article 58576. https://doi.org/10.1371/journal.pone.0058576
    • Geelen, C. C., van Greevenbroek, M. M., van Rossum, E. F., Schaper, N. C., Nijpels, G., 't Hart, L. M., Schalkwijk, C. G., Ferreira, I., van der Kallen, C. J., Sauerwein, H. P., Dekker, J. M., Stehouwer, C. D., & Havekes, B. (2013). BclI Glucocorticoid Receptor Polymorphism Is Associated With Greater Body Fatness: The Hoorn and CODAM Studies. Journal of Clinical Endocrinology & Metabolism, 98(3), E595-E599. https://doi.org/10.1210/jc.2012-3442
    • Wlazlo, N., van Greevenbroek, M. M. J., Ferreira, I., Jansen, E. H., Feskens, E. J., van der Kallen, C. J. H., Schalkwijk, C. G., Bravenboer, B., & Stehouwer, C. D. A. (2013). Iron Metabolism Is Associated With Adipocyte Insulin Resistance and Plasma Adiponectin: The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) study.Diabetes Care, 36(2), 309-315. https://doi.org/10.2337/dc12-0505
  • 2012
    • Wlazlo, N., van Greevenbroek, M. M. J., Ferreira, I., Jansen, E. H. J. M., Feskens, E. J. M., van der Kallen, C. J. H., Schalkwijk, C. G., Bravenboer, B., & Stehouwer, C. D. A. (2012). Low-grade inflammation and insulin resistance independently explain substantial parts of the association between body fat and serum C3: The CODAM study. Metabolism-Clinical and Experimental, 61(12), 1787-1796. https://doi.org/10.1016/j.metabol.2012.05.015
    • van Greevenbroek, M. M. J., Ghosh, S., van der Kallen, C. J. H., Brouwers, M. C. G. J., Schalkwijk, C. G., & Stehouwer, C. D. A. (2012). Up-Regulation of the Complement System in Subcutaneous Adipocytes from Nonobese, Hypertriglyceridemic Subjects Is Associated with Adipocyte Insulin Resistance. Journal of Clinical Endocrinology & Metabolism, 97(12), 4742-4752. https://doi.org/10.1210/jc.2012-2539
    • Brouwers, M. C. G. J., van Greevenbroek, M. M. J., Stehouwer, C. D. A., de Graaf, J., & Stalenhoef, A. F. H. (2012). The genetics of familial combined hyperlipidaemia. Nature Reviews Endocrinology, 8(6), 352-362. https://doi.org/10.1038/nrendo.2012.15
    • Hertle, E., van Greevenbroek, M. M. J., & Stehouwer, C. D. A. (2012). Complement C3: an emerging risk factor in cardiometabolic disease. Diabetologia, 55(4), 881-884. https://doi.org/10.1007/s00125-012-2462-z
    • Vaarhorst, A. A. M., Lu, Y., Heijmans, B. T., Dolle, M. E. T., Boehringer, S., Putter, H., Imholz, S., Merry, A. H. H., van Greevenbroek, M. M., Jukema, J. W., Gorgels, A. P. M., van den Brandt, P. A., Mueller, M., Schouten, L. J., Feskens, E. J. M., Boer, J. M. A., & Slagboom, P. E. (2012). Literature-Based Genetic Risk Scores for Coronary Heart Disease The Cardiovascular Registry Maastricht (CAREMA) Prospective Cohort Study. Circulation : Cardiovascular Genetics, 5(2), 202-209. https://doi.org/10.1161/CIRCGENETICS.111.960708
    • Van Woudenbergh, G. J., Kuijsten, A., Van der Kallen, C. J., Van Greevenbroek, M. M., Stehouwer, C. D., Blaak, E. E., & Feskens, E. J. M. (2012). Comparison of fatty acid proportions in serum cholesteryl esters among people with different glucose tolerance status: The CoDAM study. Nutrition Metabolism and Cardiovascular Diseases, 22(2), 133-140. https://doi.org/10.1016/j.numecd.2010.05.008