• 2010
    • Laeremans, H., Rensen, S. S. M., Ottenheijm, H. C. J., Smits, J. F. M., & Blankesteijn, W. M. (2010). Wnt/frizzled signalling modulates the migration and differentiation of immortalized cardiac fibroblasts. Cardiovascular Research, 87(3), 514-523. https://doi.org/10.1093/cvr/cvq067
    • Martins, P. A. D. C., Leptidis, S., Salic, K., & De Windt, L. J. (2010). MicroRNA Regulation in Cardiovascular Disease. Current Drug Targets, 11(8), 900-906. https://doi.org/10.2174/138945010791591322
    • Cosemans, J. M. E. M., Van Kruchten, R., Olieslagers, S., Schurgers, L. J., Verheyen, F. K., Munnix, I. C. A., Waltenberger, J., Angelillo-Scherrer, A., Hoylaerts, M. F., Carmeliet, P., & Heemskerk, J. W. M. (2010). Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization. Journal of Thrombosis and Haemostasis, 8(8), 1797-1808. https://doi.org/10.1111/j.1538-7836.2010.03935.x
    • Steinbusch, L. K. M., Wijnen, W., Schwenk, R. W., Coumans, W. A., Hoebers, N. T. H., Ouwens, D. M., Diamant, M., Bonen, A., Glatz, J. F. C., & Luiken, J. J. F. P. (2010). Differential regulation of cardiac glucose and fatty acid uptake by endosomal pH and actin filaments. American Journal of Physiology-Cell Physiology, 298(6), C1549-C1559. https://doi.org/10.1152/ajpcell.00334.2009
    • Kuster, G. M., Nietlispach, F., Kiowski, W., Schindler, R., Bernheim, A. M., Schuetz, P., Mueller, B., Morgenthaler, N. G., Rueter, F., Riesen, W., Rickli, H., & Brunner-La Rocca, H. P. (2010). Role of RAS Inhibition in the Regulation of Cu/Zn-SOD in the Cardiac and Peripheral Arterial Beds in Humans. Clinical Pharmacology & Therapeutics, 87(6), 686-692. https://doi.org/10.1038/clpt.2010.36
    • Tijsen, A. J., Creemers, E. E., Moerland, P. D., de Windt, L. J., van der Wal, A. C., Kok, W. E., & Pinto, Y. M. (2010). MiR423-5p As a Circulating Biomarker for Heart Failure. Circulation Research, 106(6), 1035-U63. https://doi.org/10.1161/CIRCRESAHA.110.218297
    • van Oort, R. J., Respress, J. L., Li, N., Reynolds, C., De Almeida, A. C., Skapura, D. G., De Windt, L. J., & Wehrens, X. H. T. (2010). Accelerated Development of Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction in an RyR2-R176Q Knockin Mouse Model. Hypertension, 55(4), 932-938. https://doi.org/10.1161/HYPERTENSIONAHA.109.146449
    • Muzzarelli, S., Brunner-La Rocca, H., Pfister, O., Foglia, P., Moschovitis, G., Mombelli, G., & Stricker, H. (2010). Adherence to the medical regime in patients with heart failure. European journal of heart failure, 12(4), 389-396. https://doi.org/10.1093/eurjhf/hfq015
    • Verkaar, F., Blankesteijn, W. M., Smits, J. F. M., & Zaman, G. J. R. (2010). beta-Galactosidase enzyme fragment complementation for the measurement of Wnt/beta-catenin signaling. Faseb Journal, 24(4), 1205-1217. https://doi.org/10.1096/fj.09-141671
    • McCurdy, S., Baicu, C. F., Heymans, S., & Bradshaw, A. D. (2010). Cardiac extracellular matrix remodeling: Fibrillar collagens and Secreted Protein Acidic and Rich in Cysteine (SPARC). Journal of Molecular and Cellular Cardiology, 48(3), 544-549. https://doi.org/10.1016/j.yjmcc.2009.06.018
    • Schalla, S., Bekkers, S. C., Dennert, R., van Suylen, R. J., Waltenberger, J., Leiner, T., Wildberger, J., Crijns, H. J., & Heymans, S. (2010). Replacement and reactive myocardial fibrosis in idiopathic dilated cardiomyopathy: comparison of magnetic resonance imaging with right ventricular biopsy. European journal of heart failure, 12(3), 227-231. https://doi.org/10.1093/eurjhf/hfq004
    • Vanhoutte, D., & Heymans, S. (2010). TIMPs and cardiac remodeling: 'Embracing the MMP-independent-side of the family'. Journal of Molecular and Cellular Cardiology, 48(3), 445-453. https://doi.org/10.1016/j.yjmcc.2009.09.013
    • Kriemler, S., Zahner, L., Schindler, C., Meyer, U., Hartmann, T., Hebestreit, H., Brunner-La Rocca, H. P., van Mechelen, W., & Puder, J. J. (2010). Effect of school based physical activity programme (KISS) on fitness and adiposity in primary schoolchildren: cluster randomised controlled trial. BMJ, 340, 8. https://doi.org/10.1136/bmj.c785
    • Schellings, M. W. M., Vanhoutte, D., van Almen, G. C., Swinnen, M., Leenders, J. J. G., Kubben, N., van Leeuwen, R. E. W., Hofstra, L., Heymans, S., & Pinto, Y. M. (2010). Syndecan-1 Amplifies Angiotensin II-Induced Cardiac Fibrosis. Hypertension, 55(2), 249-U87. https://doi.org/10.1161/HYPERTENSIONAHA.109.137885
    • Dennert, R. M., van Paassen, P., Schalla, S., Kuznetsova, T., Alzand, B. S. N., Staessen, J. A., Velthuis, S., Crijns, H. J., Tervaert, J. W. C., & Heymans, S. (2010). Cardiac Involvement in Churg-Strauss Syndrome. Arthritis & Rheumatism, 62(2), 627-634. https://doi.org/10.1002/art.27263
    • van Rooij, E., Fielitz, J., Sutherland, L. B., Thijssen, V. L., Crijns, H. J., Dimaio, M. J., Shelton, J., De Windt, L. J., Hill, J. A., & Olson, E. N. (2010). Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen Receptor. Circulation Research, 106(1), 155-U315. https://doi.org/10.1161/CIRCRESAHA.109.207084
    • Lenaers, E., Feyter, H. M., Hoeks, J., Schrauwen, P., Schaart, G., Nabben, M., Nicolay, K., Prompers, J. J., & Hesselink, M. K. (2010). Adaptations in mitochondrial function parallel, but fail to rescue, the transition to severe hyperglycemia and hyperinsulinemia: a study in Zucker diabetic fatty rats.Obesity, 18(6), 1100-1107. https://doi.org/10.1038/oby.2009.372
    • Heather, L. C., Cole, M. A., Atherton, H. J., Coumans, W. A., Evans, R. D., Tyler, D. J., Glatz, J. F. C., Luiken, J. J. F. P., & Clarke, K. (2010). Adenosine Monophosphate-Activated Protein Kinase Activation, Substrate Transporter Translocation, and Metabolism in the Contracting Hyperthyroid Rat Heart. Endocrinology, 151(1), 422-431. https://doi.org/10.1210/en.2009-0593
    • PROTECT Steering Committee, & Heymans, S. (2010). Design and Rationale of the PROTECT Study: A Placebo-controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function. Journal of Cardiac Failure, 16(1), 25-35. https://doi.org/10.1016/j.cardfail.2009.10.025
    • el Azzouzi, H., van Oort, R. J., van der Nagel, R., Sluiter, W., Bergmann, M. W., & De Windt, L. J. (2010). MEF2 transcriptional activity maintains mitochondrial adaptation in cardiac pressure overload. European journal of heart failure, 12(1), 4-12. https://doi.org/10.1093/eurjhf/hfp165
    • Glatz, J. F. C., Luiken, J. J. F. P., & Bonen, A. (2010). Membrane Fatty Acid Transporters as Regulators of Lipid Metabolism: Implications for Metabolic Disease. Physiological Reviews, 90(1), 367-417. https://doi.org/10.1152/physrev.00003.2009
    • van den Borne, S. W. M., Diez, J., Blankesteijn, W. M., Verjans, J., Hofstra, L., & Narula, J. (2010). Myocardial remodeling after infarction: the role of myofibroblasts. Nature Reviews Cardiology, 7(1), 30-37. https://doi.org/10.1038/nrcardio.2009.199
    • Schwenk, R. W., Holloway, G. P., Luiken, J. J. F. P., Bonen, A., & Glatz, J. F. C. (2010). Fatty acid transport across the cell membrane: Regulation by fatty acid transporters. Prostaglandins Leukotrienes and Essential Fatty Acids, 82(4-6), 149-154. https://doi.org/10.1016/j.plefa.2010.02.029
    • Dennert, R., Velthuis, S., Schalla, S., Eurlings, L. W., van Suylen, R.-J., van Paassen, P., Tervaert, J. W. C., Wolffs, P., Goossens, V. J., Bruggeman, C., Waltenberger, J., Crijns, H. J., & Heymans, S. (2010). Intravenous immunoglobulin therapy for patients with idiopathic cardiomyopathy and endomyocardial biopsy-proven high PVB19 viral load. Antiviral Therapy, 15(2), 193-201. https://doi.org/10.3851/IMP1516
    • Dennert, R., Velthuis, S., Westermann, D., Donker, D. W., Schalla, S., van Suylen, R.-J., & Heymans, S. (2010). Parvovirus-B19-associated fulminant myocarditis successfully treated with immunosuppressive and antiviral therapy. Antiviral Therapy, 15(4), 681-685. https://doi.org/10.3851/IMP1563
  • 2009
    • van den Borne, S. W. M., van de Schans, V. A. M., Strzelecka, A. E., Vervoort-Peters, H. T. M., Lijnen, P. M., Cleutjens, J. P. M., Smits, J. F. M., Daemen, M. J. A. P., Janssen, B. J. A., & Blankesteijn, W. M. (2009). Mouse strain determines the outcome of wound healing after myocardial infarction. Cardiovascular Research, 84(2), 273-82. https://doi.org/10.1093/cvr/cvp207
    • Schellings, M. W. M., Vanhoutte, D., Swinnen, M., Cleutjens, J. P., Debets, J., van Leeuwen, R. E. W., d'Hooge, J., Van de Werf, F., Carmeliet, P., Pinto, Y. M., Sage, E. H., & Heymans, S. (2009). Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction. Journal of Experimental Medicine, 206(1), 113-23. https://doi.org/10.1084/jem.20081244
    • Luiken, J. J. F. P., Niessen, H. E. C., Coort, S. L. M., Hoebers, N., Coumans, W. A., Schwenk, R. W., Bonen, A., & Glatz, J. F. (2009). Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibition in vivo does not alter cardiac long-chain fatty acid uptake and oxidation rates. Biochemical Journal, 419(2), 447-55. https://doi.org/10.1042/BJ20082159
  • 2008
    • van den Borne, S. W. M., Cleutjens, J. P. M., Hanemaaijer, R., Creemers, E. E., Smits, J. F. M., Daemen, M. J. A. P., & Blankesteijn, W. M. (2008). Increased matrix metalloproteinase-8 and -9 activity in patients with infarct rupture after myocardial infarction. Cardiovascular Pathology, 18(1), 37-43. https://doi.org/10.1016/j.carpath.2007.12.012
    • Luiken, J. J. F. P., Vertommen, D., Coort, S. L. M., Habets, D. D. J., El Hasnaoui, M. M., Pelsers, M. M. A. L., Viollet, B., Bonen, A., Hue, L., Rider, M. H., & Glatz, J. F. (2008). Identification of protein kinase D as a novel contraction-activated kinase linked to GLUT4-mediated glucose uptake independent of AMPK. Cellular Signalling, 20, 543-555. https://doi.org/10.1016/j.cellsig.2007.11.007
    • Hoeks, J., Briede, J. J., de Vogel, J., Schaart, G., Nabben, M., Kornips, E., Hesselink, M. K., & Schrauwen, P. (2008). Mitochondrial function, content and ROS production in rat skeletal muscle: effect of high-fat feeding. Febs Letters, 582(4), 510-6. https://doi.org/10.1016/j.febslet.2008.01.013
    • Nabben, M., Hoeks, J., Briede, J. J., Glatz, J. F., Kornips, E., Hesselink, M. K., & Schrauwen, P. (2008). The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice. Febs Letters, 582(30), 4147-4152. https://doi.org/10.1016/j.febslet.2008.11.016
  • 2007
    • Ouwens, DM., Diamant, M., Fodor, M., Habets, D. D. J., Pelsers, M. M. A. L., El Hasnaoui, M. M., Dang, Z. C., van den Brom, C. E., Vlasblom, R., Rietdijk, A., Boer, C., Coort, S. L. M., Glatz, J. F., & Luiken, J. J. F. P. (2007). Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification. Diabetologia, 50(9), 1938-48. https://doi.org/10.1007/s00125-007-0735-8
    • Coort, S. L. M., Bonen, A., van der Vusse, G. J., Glatz, J. F., & Luiken, J. J. F. P. (2007). Cardiac substrate uptake and metabolism in obesity and type-2 diabetes: Role of sarcolemmal substrate transporters. Molecular and Cellular Biochemistry, 299(1-2), 5-18. https://doi.org/10.1007/s11010-005-9030-5
    • van de Schans, V. A. M., van den Borne, S. W. M., Strzelecka, A. E., Janssen, B. J., van der Velden, J. L., Langen, R. C., Wynshaw Boris, A., Smits, J. F., & Blankesteijn, W. M. (2007). Interruption of Wnt Signaling Attenuates the Onset of Pressure Overload-Induced Cardiac Hypertrophy. Hypertension, 49(3), 473-480. https://doi.org/10.1161/01.HYP.0000255946.55091.24
    • Pelsers, M. M., Tsintzas, K., Boon, H., Jewell, K., Norton, L., Luiken, J. J. F. P., Glatz, J. F., & van Loon, L. J. (2007). Skeletal muscle fatty acid transporter protein expression in type 2 diabetes patients compared with overweight, sedentary men and age-matched, endurance-trained cyclists.Acta Physiologica, 190(3), 209-219. https://doi.org/10.1111/j.1748-1716.2007.01698.x
  • 2006
    • Jones, E. A. V., le Noble, F., & Eichmann, A. (2006). What determines blood vessel structure? Genetic prespecification vs. hemodynamics. Physiology, 21, 388-95. https://doi.org/10.1152/physiol.00020.2006
    • van Haaften, R. I. M., Schroen, B. L., Janssen, B. J., van Erk, A. A., Debets, J. J., Smeets, H. J., Smits, J. F., van den Wijngaard, A., Pinto, Y. M., & Evelo, C. T. (2006). Biologically relevant effects of mRNA amplification on gene expression profiles. BMC Bioinformatics, 7, 200. https://doi.org/10.1186/1471-2105-7-200
    • van Empel, V. P. M., Bertrand, A. T., van Oort, R. J., van der Nagel, R., Engelen, M. P. K. J., van Rijen, H. V., Doevendans, P. A. F. M., Crijns, H. J. G. M., Ackerman, S. L., Sluiter, W., & de Windt, L. J. (2006). EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant. Journal of the American College of Cardiology, 48(4), 824-832. https://doi.org/10.1016/j.jacc.2006.02.075
    • Chabowski, A. M. I., Coort, S. L. M., Calles-Escandon, J. T. NN., Glatz, J. F., Luiken, J. J. F. P., & Bonen, A. (2006). Prolonged AMPK activation increases the expression of fatty acid transporters in cardiac myocytes and perfused hearts. Molecular and Cellular Biochemistry, 288, 201-212. https://doi.org/10.1007/s11010-006-9140-8
  • 2005
    • Chabowski, A., Coort, S. L. M., Calles-Escandon, J., Tandon, NN., Glatz, J. F., Luiken, J. J. F. P., & Bonen, A. (2005). The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR. Febs Letters, 579, 2428-2432. https://doi.org/10.1016/j.febslet.2004.11.118
    • Meex, S. J. R., van der Kallen, C. J. H., van Greevenbroek, M. M., Eurlings, P. M., El Hasnaoui, M. M., Evelo, C. T., Lindsey, P. J., Luiken, J. J. F. P., Glatz, J. F., & de Bruin, T. W. (2005). Up-regulation of CD36/FAT in preadipocytes in familial combined hyperlipidemia. Faseb Journal, 19(14), 2063-2065. https://doi.org/10.1096/fj.04-2403fje
  • 2004
    • Sharma, U. C., Pokharel, S., van Brakel, T. J., van Berlo, J. H., Cleutjens, J. P. M., Schroen, B., André, S., Crijns, H. J. G. M., Gabius, H.-J., Maessen, J., & Pinto, Y. M. (2004). Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation, 110(19), 3121-8. https://doi.org/10.1161/01.CIR.0000147181.65298.4D
    • Schroen, B., Heymans, S., Sharma, U., Blankesteijn, W. M., Pokharel, S., Cleutjens, J. P. M., Porter, J. G., Evelo, C. T. A., Duisters, R., van Leeuwen, R. E. W., Janssen, B. J. A., Debets, J. J. M., Smits, J. F. M., Daemen, M. J. A. P., Crijns, H. J. G. M., Bornstein, P., & Pinto, Y. M. (2004). Thrombospondin-2 is essential for myocardial matrix integrity: increased expression identifies failure-prone cardiac hypertrophy. Circulation Research, 95(5), 515-522. https://doi.org/10.1161/01.RES.0000141019.20332.3e
    • De Celle, T., Cleutjens, J. P., Blankesteijn, W. M., Debets, J. J., Smits, J. F., & Janssen, B. J. (2004). Long-term structural and functional consequences of cardiac ischaemia-reperfusion injury in vivo in mice. Experimental Physiology, 89(5), 605-15. https://doi.org/10.1113/expphysiol.2004.027649
    • Beguin, S., Keularts, I., Al Dieri, R., Bellucci, S., Caen, J., & Hemker, H. C. (2004). Fibrin polymerization is crucial for thrombin generation in platelet-rich plasma in a VWF-GPlb-dependent process, defective in Bernhard-Soulier syndrome. Journal of Thrombosis and Haemostasis, 2(1), 170-176. https://doi.org/10.1111/j.1538-7836.2004.00558.x
  • 2003
    • Schrauwen, P., Hoeks, J., Schaart, G., Kornips, C. F. P., Binas, B., van der Vusse, G. J., van Bilsen, M., Luiken, J. J. F. P., Coort, S. L. M., Glatz, J. F., Saris, W. H. M., & Hesselink, M. K. C. (2003). Uncoupling protein 3 as a mitochondrial fatty acid anion exporter. Faseb Journal, 17(15), 2272-2274. https://doi.org/10.1096/fj.03-0515fje
  • 2001
    • Blankesteijn, W. M., Creemers, E., Lutgens, E., Cleutjens, J. P., Daemen, M. J., & Smits, J. F. (2001). Dynamics of cardiac wound healing following myocardial infarction: observations in genetically altered mice. Acta Physiologica Scandinavica, 173(1), 75-82. https://doi.org/10.1046/j.1365-201X.2001.00887.x
    • van Gijn, M. E., Snel, F., Cleutjens, J. P., Smits, J. F., & Blankesteijn, W. M. (2001). Overexpression of components of the Frizzled-Dishevelled cascade results in apoptotic cell death, mediated by beta-catenin. Experimental Cell Research, 265(1), 46-53. https://doi.org/10.1006/excr.2001.5174