Julie Staals

Professor

Prof.  Julie Staals is working as a clinical neurologist at Maastricht UMC+. Her specialisation is neurovascular diseases. She has obtained her medical degree at Maastricht University. Afterwards, she did a parallel tract in neurology training and PhD research project, both were finished in 2009. In 2013 she did a short research fellowship at the Brain Research Imaging Center in Edinburgh, UK. Her research focus is on clinical studies in cerebral small vessel disease, mainly the effects of hypertension, the rol of endothelial function, blood-brain barrier and the neurovascular unit, advanced imaging, and the cognitive consequences of this disease. She developed the ‘total SVD score’, a highly cited score for MRI severity of cerebral small vessel disease. Other clinical research topics are intracerebral haemorrhage and acute stroke treatments.

Julie Staals  has been appointed as professor 'Neurovascular disease' as of 1 April 2024. Julie is neurologist at Maastricht UMC+ and leader of the stroke clinic. Her research aims at unravelling the pathophysiology of cerebral small vessel disease, a common ageing-related disease leading to stroke and dementia, which falls within the research programs of both CARIM and MHeNS. Furthermore she is involved in clinical studies on the very successfull acute endovascular stroke treatment. The inaugural lecture will follow later.

She is currently involved in:
SVDs@target, a EU Horizon2020 multicenter project on mechanisms in cerebral small vessel disease (www.svds-at-target.eu)

CRUCIAL, a EU Horizon2020 multicenter project on microvascular rarefaction in vascular cognitive impairment and heart failure (www.crucial-project.eu)

MRCLEAN trials, acute clinical stroke trials aiming at improving outcome in endovascular treatment (www.contrast-consortium.nl)

 

Department of Neurology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

  • 2026
    • Doheim, M. F., Knapen, R. R. M. M., Dippel, D. W. J., Staals, J., Hofmeijer, J., van Es, A. C. G. M., Coutinho, J. M., van der Leij, C., Nogueira, R. G., van Oostenbrugge, R. J., van Zwam, W. H., & MR CLEAN Registry Investigators (2026). Association of anesthesia strategies with outcomes in endovascular treatment for distal and medium vessel occlusions: A propensity score-matched analysis of the MR CLEAN registry and meta-analysis. European Stroke Journal, 11(1), Article 23969873251352406. https://doi.org/10.1177/23969873251352406
    • Reitsma, F. J., van Kuijk, S. M. J., Werring, D. J., Banerjee, G., Cordonnier, C., Kaaouana, O., Puy, L., Biffi, A., Viswanathan, A., van Oostenbrugge, R. J., Staals, J., & Rouhl, R. P. W. (2026). Development and external validation of the LEAN score to predict late seizures after intracerebral haemorrhage. European Stroke Journal, 11(1), Article 23969873251350882. https://doi.org/10.1177/23969873251350882
  • 2025
    • Dassen, S., Van Es, A., Roozenbeek, B., Van De Graaf, R., Roos, Y., Majoie, C., Ghariq, E., Kruyt, N., Fischer, U., Van Oostenbrugge, R., Van Zwam, W., & Staals, J. (2025). Time to Endovascular Treatment and Clinical Outcome in Acute Ischemic Stroke With M2-Segment Occlusion. Journal of the American Heart Association, 14(22), 1-10. Article e043984. https://doi.org/10.1161/JAHA.125.043984
    • Verstappen, D., de Jong, J. J. A., Voorter, P. H. M., van Dinther, M., van Oostenbrugge, R. J., Staals, J., Jansen, J. F. A., & Backes, W. H. (2025). DCE-MRI reveals spatial pattern in heterogeneous blood-brain barrier leakage within white matter in cerebral small vessel disease. Journal of Cerebral Blood Flow and Metabolism, 45(11), 2104-2114. Article 0271678X251364151. https://doi.org/10.1177/0271678X251364151
    • Voorter, P. H. M., van Dinther, M., Drenthen, G. S., Elschot, E. P., Staals, J., van Oostenbrugge, R. J., Jansen, J. F. A., & Backes, W. H. (2025). Vessel architecture imaging reveals microvascular rarefaction and capillary-to-arteriole shift in cerebral small vessel disease. Journal of Cerebral Blood Flow and Metabolism, 45(11), 2092-2103. https://doi.org/10.1177/0271678X251358968
    • Vermeulen, E., Bruneau, M., Potters, F., Podlogar, M., Jolink, W. M. T., Haeren, R., Wagemans, B. A. J. M., Staals, J., Meijer, F. J. A., Klijn, C. J. M., Vinke, S., De Vries, J., van Zwam, W. H., & Boogaarts, H. D. (2025). Evaluating the need for late angiography for complete obliteration of AVMs after endovascular treatment: collaborative AVM center experience and a systematic review. Journal of Neurointerventional Surgery. https://doi.org/10.1136/jnis-2025-024046
    • Bruijel, J., Stapert, S., Vermeeren, A., Staals, J., Ponsford, J., & van Heugten, C. (2025). Course of Fatigue and Sleep After Moderate to Severe Traumatic Brain Injury. Journal of Head Trauma Rehabilitation. Advance online publication. https://doi.org/10.1097/HTR.0000000000001078
    • Schuurman, B., Mess, W. H., Postma, A. A., Staals, J., & van Weert, S. (2025). Pearls & Oy-sters: Eagle Syndrome in a Patient With Neurologic Deficit Upon Head Rotation. Neurology, 105(1), Article e213764. https://doi.org/10.1212/WNL.0000000000213764
    • Olthuis, S. G. H., Pinckaers, F. M. E., Robbe, M. M. Q., de Ridder, I. R., Hoving, J. W., Venema, E., Daems, J. D., Pirson, F. A. V. A., Staals, J., Emmer, B. J., Lingsma, H. F., Roosendaal, S. D., van der Hoorn, A., Koopman, M. S., Postma, A. A., Dippel, D. W. J., Majoie, C. B., van Oostenbrugge, R. J., van Zwam, W. H., & MR CLEAN-LATE (Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands for Late Arrivals) Investigators (2025). CT Perfusion Imaging After Selection for Late-Window Endovascular Stroke Treatment: Secondary Analysis of the MR CLEAN-LATE Randomized Trial. JAMA Neurology, 82(6), 589-596. https://doi.org/10.1001/jamaneurol.2025.0716
    • Van der Taelen, L., Briones, A. M., Unger, T., Staals, J., van Oostenbrugge, R. J., & Foulquier, S. (2025). Circulating immune cells in cerebral small vessel disease: a systematic review. Biogerontology, 26(3), Article 101. https://doi.org/10.1007/s10522-025-10250-x
    • Dassen, S., Robbe, Q., Wagemans, B., Knapen, R., Olthuis, S., Jacobi, L., van der Leij, C., Fischer, U., Ghariq, E., Kruyt, N., van der Steen, W., Lecouffe, N., van der Lugt, A., Majoie, C., van Zwam, W., Es, A. V., & Staals, J. (2025). M2 vessel occlusion characteristics and outcome after endovascular therapy: A post-hoc pooled analysis of MR CLEAN MED, NO-IV and LATE. Interventional Neuroradiology. Advance online publication. https://doi.org/10.1177/15910199251349012
    • Psychogios, M., Brehm, A., Ribo, M., Rizzo, F., Strbian, D., Raety, S., Arenillas, J. F., Martinez-Galdamez, M., Hajdu, S. D., Michel, P., Gralla, J., Piechowiak, E. I., Kaiser, D. P. O., Puetz, V., van den Bergh, F., De Raedt, S., Bellante, F., Dusart, A., Hellstern, V., ... Staals, J. (2025). Endovascular Treatment for Stroke Due to Occlusion of Medium or Distal Vessels. New England Journal of Medicine, 392(14), 1374-1384. Article NEJMoa2408954. https://doi.org/10.1056/NEJMoa2408954
    • Stringer, M. S., Blair, G. W., Kopczak, A., Kerkhofs, D., Thrippleton, M. J., Chappell, F. M., Maniega, S. M., Brown, R., Shuler, K., Hamilton, I., Garcia, D. J., Doubal, F. N., Clancy, U., Sakka, E., Poliakova, T., Janssen, E., Duering, M., Ingrisch, M., Staals, J., ... Wardlaw, J. M. (2025). Cerebrovascular Function in Sporadic and Genetic Cerebral Small Vessel Disease. Annals of Neurology, 97(3), 483-498. https://doi.org/10.1002/ana.27136
    • Peeters, M. T. J., Postma, A. A., van Oostenbrugge, R. J., Henneman, W. J. P., & Staals, J. (2025). Dual-energy CT angiography in detecting underlying causes of intracerebral hemorrhage: an observational cohort study. Neuroradiology, 67(2), 331-338. https://doi.org/10.1007/s00234-024-03473-1
    • Ruthmann, F., Lo, J. W., Mendyk-Bordet, A.-M., Allart, E., Köhler, S., Klimkowicz-Mrowiec, A., Staals, J., Sachdev, P. S., Bordet, R., Dondaine, T., & Stroke and Cognition (STROKOG) Collaboration (2025). Prevalence of poststroke anxiety and its associations with global cognitive impairment: An individual participant data analysis. Journal of Affective Disorders, 369, 1136-1144. https://doi.org/10.1016/j.jad.2024.10.099
    • Doheim, M. F., Knapen, R. R. M. M., Staals, J., Schonewille, W. J., Dippel, D. W. J., Van Es, A. C. G. M., Lingsma, H. F., Van Der Leij, C., Majoie, C. B., Nogueira, R. G., Van Oostenbrugge, R. J., Van Zwam, W. H., Van Der Lugt, A., Roos, Y. B. W. E. M., Boiten, J., Albert Vos, J., Jansen, I. G. H., Mulder, M. J. H. L., Goldhoorn, R. J. B., ... MR CLEAN Registry Investigators (2025). Direct Endovascular Versus Bridging Therapy in M2 Segment Occlusion of Middle Cerebral Artery: A MR CLEAN Registry Study. Stroke. Advance online publication. https://doi.org/10.1161/STROKEAHA.125.051967
    • Voorter, P. H. M., Stringer, M. S., van Dinther, M., Kerkhofs, D., Dewenter, A., Blair, G. W., Thrippleton, M. J., Jaime Garcia, D., Chappell, F. M., Janssen, E., Kopczak, A., Staals, J., Ingrisch, M., Duering, M., Doubal, F. N., Dichgans, M., van Oostenbrugge, R. J., Jansen, J. F. A., Wardlaw, J. M., ... SVDs@target Consortium (2025). Heterogeneity and Penumbra of White Matter Hyperintensities in Small Vessel Diseases Determined by Quantitative MRI. Stroke, 56(1), 128-137. https://doi.org/10.1161/STROKEAHA.124.047910
  • 2024
    • Robbe, M. M. Q., Pinckaers, F. M. E., Wagemans, B. A. J. M., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Additional value of CTP maps in occlusion detection on CTP angiographic reconstructions for ischemic stroke. European Journal of Radiology, 181, Article 111789. https://doi.org/10.1016/j.ejrad.2024.111789
    • Robbe, M. M. Q., Pinckaers, F. M. E., Wagemans, B. A. J. M., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Angiographic reconstructions of CT perfusion for occlusion detection in ischemic stroke. European Journal of Radiology, 181, Article 111819. https://doi.org/10.1016/j.ejrad.2024.111819
    • Fandler-Höfler, S., Eppinger, S., Ambler, G., Nash, P., Kneihsl, M., Lee, K. J., Lim, J. S., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sanchez, L., Martínez-Domeño, A., Inamura, S., Yoshifuji, K., ... Microbleeds International Collaborative Network (2024). Sex Differences in Frequency, Severity, and Distribution of Cerebral Microbleeds. Jama network open, 7(10), Article e2439571. https://doi.org/10.1001/jamanetworkopen.2024.39571
    • Coenen, M., de Kort, F. A. S., Weaver, N. A., Kuijf, H. J., Aben, H. P., Bae, H.-J., Bordet, R., Chen, C. L., Dewenter, A., Doeven, T., Dondaine, T., Duering, M., Fang, R., van der Giessen, R. S., Kim, J., Kim, B. J., de Kort, P. L. M., Koudstaal, P., Lee, M., ... Biesbroek, J. M. (2024). Strategic white matter hyperintensity locations associated with post-stroke cognitive impairment: a multicenter study in 1568 stroke patients. International journal of stroke, 19(8), 916-924. https://doi.org/10.1177/17474930241252530
    • van Dinther, M., Voorter, P. H. M., Zhang, E., van Kuijk, S. M. J., Jansen, J. F. A., van Oostenbrugge, R. J., Backes, W. H., & Staals, J. (2024). The neurovascular unit and its correlation with cognitive performance in patients with cerebral small vessel disease: a canonical correlation analysis approach. Geroscience, 46(5), 5061-5073. https://doi.org/10.1007/s11357-024-01235-8
    • Knapen, R. R. M. M., Goldhoorn, R.-J. B., Hofmeijer, J., Lycklamaa Nijeholt, G. J., van den Berg, R., van den Wijngaard, I. R., van Oostenbrugge, R. J., van Zwam, W. H., van der Leij, C., MR CLEAN Registry Investigators, Goldhoorn, R.-J., Hinsenveld, W., Staals, J., Postma - Jacobi, L., Brans, R., Olthuis, S., & Pinckaers, F. (2024). Balloon Guide Catheter Versus Non-Balloon Guide Catheter: A MR CLEAN Registry Analysis. Stroke: vascular and interventional neurology, 4(4), Article e001103. https://doi.org/10.1161/SVIN.123.001103
    • Starmans, N. L. P., Wolters, F. J., Leeuwis, A. E., Bron, E. E., de Bresser, J., Brunner-La Rocca, H. P., Staals, J., Muller, M., Biessels, G. J., Kappelle, L. J., & Heart-Brain Connection Consortium (2024). Orthostatic hypotension, cognition and structural brain imaging in hemodynamically impaired patients. Journal of the Neurological Sciences, 461, Article 123026. https://doi.org/10.1016/j.jns.2024.123026
    • Van Voorst, H., Hoving, J. W., Koopman, M. S., Daems, J. D., Peerlings, D., Buskens, E., Lingsma, H., Marquering, H. A., De Jong, H. W. A. M., Berkhemer, O. A., Van Zwam, W. H., Van Walderveen, M. A. A., Van Den Wijngaard, I. R., Dippel, D. W. J., Yoo, A. J., Campbell, B., Kunz, W. G., Majoie, C. B., Emmer, B. J., ... MR CLEAN Registry Investigators (2024). Costs and health effects of CT perfusion-based selection for endovascular thrombectomy within 6 hours of stroke onset: a model-based health economic evaluation. Journal of Neurology Neurosurgery and Psychiatry, 95(6), 515-527. https://doi.org/10.1136/jnnp-2023-331862
    • van der Knaap, N., de Vreeze, F., van Rosmalen, F., Wintjens, M. S. J. N., van Santen, S., Linden, D. E. J., Staals, J., van Mook, W. N. K. A., Jansen, J. F. A., van der Horst, I. C. C., van Bussel, B. C. T., & Ariës, M. J. H. (2024). The incidence of neurological complications in mechanically ventilated COVID-19 ICU patients: An observational single-center cohort study in three COVID-19 periods. Clinical Neurology and Neurosurgery, 241, Article 108311. https://doi.org/10.1016/j.clineuro.2024.108311
    • Senff, J. R., Singh, S. D., Pasi, M., Jolink, W. M. T., Rodrigues, M. A., Schreuder, F. H. B. M., Staals, J., Schreuder, T., Douwes, J. P. J., Talsma, J., McKaig, B. N., Kourkoulis, C., Yechoor, N., Anderson, C. D., Puy, L., Cordonnier, C., Wermer, M. J. H., Rothwell, P. M., Rosand, J., ... Brouwers, H. B. (2024). Long-Term Outcomes in Patients With Spontaneous Cerebellar Hemorrhage: An International Cohort Study. Stroke, 55(5), 1210-1217. https://doi.org/10.1161/STROKEAHA.123.044622
    • Prats-Sanchez, L., Camps-Renom, P., Nash, P. S., Wilson, D., Ambler, G., Best, J. G., Guasch-Jiménez, M., Ramos-Pachón, A., Martinez-Domeño, A., Lambea-Gil, Á., Díaz, G. E., Guisado-Alonso, D., Du, H., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y., Ay, H., Jung, S., Bornstein, N. M., ... Microbleeds International Collaborative Network (MICON) (2024). Statin Therapy for Secondary Prevention in Ischemic Stroke Patients With Cerebral Microbleeds. Neurology, 102(7), Article e209173. https://doi.org/10.1212/WNL.0000000000209173
    • van Voorst, H., Hoving, J. W., Koopman, M. S., Daems, J. D., Peerlings, D., Buskens, E., Lingsma, H. F., Beenen, L. F. M., de Jong, H. W. A. M., Berkhemer, O. A., van Zwam, W. H., Roos, Y. B. W. E. M., van Walderveen, M. A. A., van den Wijngaard, I., Dippel, D. W. J., Yoo, A. J., Campbell, B. C. V., Kunz, W. G., Emmer, B. J., ... MR CLEAN Registry Investigators (2024). Cost-effectiveness of CT perfusion for the detection of large vessel occlusion acute ischemic stroke followed by endovascular treatment: a model-based health economic evaluation study. European Radiology, 34(4), 2152-2167. https://doi.org/10.1007/s00330-023-10119-y
    • Oestreich, L. K., Lo, J. W., Di Biase, M. A., Sachdev, P. S., Mok, A. H., Wright, P., Crawford, J. D., Lam, B., Traykov, L., Köhler, S., Staals, J. E., van Oostenbrugge, R., Chen, C., Desmond, D. W., Yu, K.-H., Lee, M., Klimkowicz-Mrowiec, A., Bordet, R., O'Sullivan, M. J., & Zalesky, A. (2024). Network analysis of neuropsychiatric, cognitive, and functional complications of stroke: implications for novel treatment targets. Psychiatry and Clinical Neurosciences, 78(4), 229-236. https://doi.org/10.1111/pcn.13633
    • Robbe, M. M. Q., Pinckaers, F. M. E., Olthuis, S. G. H., Bos, M. J., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Procedural Blood Pressure and Intracranial Hemorrhage on Dual-Energy Computed Tomography After Endovascular Stroke Treatment. Cardiovascular and Interventional Radiology, 47(4), 483-491. https://doi.org/10.1007/s00270-023-03619-3
    • Robbe, M. M. Q., Pinckaers, F. M. E., Santegoeds, R. G. C., Bos, M. J., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Procedural blood pressure and contrast extravasation on dual energy computed tomography after endovascular stroke treatment. Journal of Stroke & Cerebrovascular Diseases, 33(6), Article 107673. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107673
    • Wardlaw, J. M., Chabriat, H., de Leeuw, F.-E., Debette, S., Dichgans, M., Doubal, F., Jokinen, H., Katsanos, A. H., Ornello, R., Pantoni, L., Pasi, M., Pavlovic, A. M., Rudilosso, S., Schmidt, R., Staals, J., Taylor-Rowan, M., Hussain, S., & Lindgren, A. G. (2024). European stroke organisation (ESO) guideline on cerebral small vessel disease, part 2, lacunar ischaemic stroke. European Stroke Journal, 9(1), 5-68. Article 23969873231219416. https://doi.org/10.1177/23969873231219416
    • Hoving, J. W., Konduri, P. R., Tolhuisen, M. L., Koopman, M. S., van Voorst, H., Van Poppel, L. M., Daems, J. D., van Es, A. C. G. M., van Walderveen, M. A. A., Lingsma, H. F., Dippel, D. W. J., Van Zwam, W. H., Marquering, H. A., Majoie, C. B. L. M., Emmer, B. J., MR CLEAN Registry Investigators, van Oostenbrugge, R. J., Goldhoorn, R.-J., Hinsenveld, W., ... Pinckaers, F. (2024). Impact of Intracranial Volume and Brain Volume on the Prognostic Value of Computed Tomography Perfusion Core Volume in Acute Ischemic Stroke. Journal of Cardiovascular Development and Disease, 11(3), Article 80. https://doi.org/10.3390/jcdd11030080
    • Voorter, P. H. M., van Dinther, M., Jansen, W. J., Postma, A. A., Staals, J., Jansen, J. F. A., van Oostenbrugge, R. J., van der Thiel, M. M., & Backes, W. H. (2024). Blood-Brain Barrier Disruption and Perivascular Spaces in Small Vessel Disease and Neurodegenerative Diseases: A Review on MRI Methods and Insights. Journal of Magnetic Resonance Imaging, 59(2), 397-411. Article jmri28989. https://doi.org/10.1002/jmri.28989
    • Knapen, R. R. M. M., Pirson, F. A. V., Langezaal, L. C. M., Brouwer, J., Majoie, C. B. L. M., Emmer, B. J., Vos, J.-A., van Doormaal, P.-J., Yoo, A. J., Bruggeman, A. A. E., Lycklama À Nijeholt, G. J., van der Leij, C., van Oostenbrugge, R. J., van Zwam, W. H., Schonewille, W. J., MR CLEAN Registry Investigators, Goldhoorn, R.-J., Hinsenveld, W., Staals, J., ... Pirson, A.-F. (2024). Intravenous Thrombolysis Before Endovascular Treatment in Posterior Circulation Occlusions: A MR CLEAN Registry Study. Stroke, 55(2), 403-412. https://doi.org/10.1161/STROKEAHA.123.043777
    • Best, J. G., Ambler, G., Wilson, D., Du, H., Lee, K.-J., Lim, J.-S., Teo, K. C., Mak, H., Kim, Y. D., Song, T.-J., Selcuk Demirelli, D., Nishihara, M., Yoshikawa, M., Kubacka, M., Zietz, A., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y. H., Panos, L., ... Werring, D. J. (2024). Clinical Associations and Prognostic Value of MRI-Visible Perivascular Spaces in Patients With Ischemic Stroke or TIA: A Pooled Analysis. Neurology, 102(1), Article e207795. https://doi.org/10.1212/WNL.0000000000207795
    • van Dinther, M. M., Hooghiemstra, A. E., Bron, E., Versteeg, A. E., Leeuwis, A., Kalay, T. E., Moonen, J., Kuipers, S. H., Backes, W., Jansen, J. F. A., van Osch, M. J. P., Biessels, G.-J., Staals, J. J., van Oostenbrugge, R., & Heart-Brain Connection Consortium (2024). Lower cerebral blood flow predicts cognitive decline in patients with vascular cognitive impairment. Alzheimer's & Dementia, 20(1), 136-144. https://doi.org/10.1002/alz.13408
    • Starmans, N. L. P., Kappelle, L. J., Muller, M., Staals, J., Teunissen, C. E., Biessels, G. J., van der Flier, W. M., Wolters, F. J., & Heart-Brain Connection Consortium (2024). Blood Pressure Variability and Plasma Biomarkers of Neuronal Injury and Alzheimer's Disease: A Clinic-Based Study of Patients with Diseases Along the Heart-Brain Axis. Journal of Alzheimer's Disease, 99(4), 1207-1215. https://doi.org/10.3233/JAD-240119
    • Stiekema, A. P. M., Vreven, L. W. A., Hummel, R. S. O., Mott, A. S., Verrijt, S. J. G. M., Joe, R. C. K., Alberto, N. A. S., Ravindran, P. K., Thommes, C., van der Kwaak, A., Staals, J., & van Heugten, C. M. (2024). The Montreal Cognitive Assessment detects cognitive deficits that go unnoticed during clinical observation in the acute phase after stroke. Brain Injury, 38(9), 687-691. https://doi.org/10.1080/02699052.2024.2341039
  • 2023
    • de Kort, F. A. S., Coenen, M., Weaver, N. A., Kuijf, H. J., Aben, H. P., Bae, H.-J., Bordet, R., Cammà, G., Chen, C. P. L. H., Dewenter, A., Duering, M., Fang, R., van der Giessen, R. S., Hamilton, O. K. L., Hilal, S., Huenges Wajer, I. M. C., Kan, C. N., Kim, J., Kim, B. J., ... Biessels, G. J. (2023). White Matter Hyperintensity Volume and Poststroke Cognition: An Individual Patient Data Pooled Analysis of 9 Ischemic Stroke Cohort Studies. Stroke, 54(12), 3021–3029. https://doi.org/10.1161/STROKEAHA.123.044297
    • Bakker, L., Ramakers, I. H. G. B., J P M Eussen, S., Choe, K., van den Hove, D. L. A., Kenis, G., Rutten, B. P. F., van Oostenbrugge, R. J., Staals, J., Ulvik, A., Ueland, P. M., Verhey, F. R. J., & Köhler, S. (2023). The role of the kynurenine pathway in cognitive functioning after stroke: A prospective clinical study. Journal of the neurological sciences, 454(1), Article 120819. https://doi.org/10.1016/j.jns.2023.120819
    • Kopczak, A., Stringer, M. S., van den Brink, H., Kerkhofs, D., Blair, G. W., van Dinther, M., Reyes, C. A., Garcia, D. J., Onkenhout, L., Wartolowska, K. A., Thrippleton, M. J., Kampaite, A., Duering, M., Staals, J., Lesnik-Oberstein, S., Muir, K. W., Middeke, M., Norrving, B., Bousser, M. G., ... TREAT-SVDs collaborators (2023). Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial. Lancet Neurology, 22(11), 991-1004. https://doi.org/10.1016/S1474-4422(23)00293-4
    • Elschot, E. P., Backes, W. H., de Jong, J. J. A., Drenthen, G. S., Wong, S. M., Staals, J., Postma, A. A., Rouhl, R. P. W., van Oostenbrugge, R. J., & Jansen, J. F. A. (2023). Assessment of the clinical feasibility of detecting subtle blood-brain barrier leakage in cerebral small vessel disease using dynamic susceptibility contrast MRI. Magnetic Resonance Imaging, 102(1), 55-61. https://doi.org/10.1016/j.mri.2023.04.004
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