• 2017
    • Brouns, S. H. A., van der Schuit, K. C. H., Stassen, P. M., Lambooij, S. L. E., Dieleman, J., Vanderfeesten, I. T. P., & Haak, H. R. (2017). Applicability of the modified Emergency Department Work Index (mEDWIN) at a Dutch emergency department. PLOS ONE, 12(3), Article e0173387. https://doi.org/10.1371/journal.pone.0173387
    • Fokkens, B. T., Mulder, D. J., Schalkwijk, C. G., Scheijen, J. L., Smit, A. J., & Los, L. I. (2017). Vitreous advanced glycation endproducts and alpha-dicarbonyls in retinal detachment patients with type 2 diabetes mellitus and non-diabetic controls. PLOS ONE, 12(3), Article e0173379. https://doi.org/10.1371/journal.pone.0173379
    • Skovgaard, D., Svensson, R. B., Scheijen, J., Eliasson, P., Mogensen, P., Hag, A. M. F., Kjær, M., Schalkwijk, C. G., Schjerling, P., Magnusson, S. P., & Couppé, C. (2017). An advanced glycation endproduct (AGE)-rich diet promotes accumulation of AGEs in Achilles tendon. Physiological Reports, 5(6), Article e13215. https://doi.org/10.14814/phy2.13215
    • Riordan, F., Ryan, K., Perry, I. J., Schulze, M. B., Andersen, L. F., Geelen, A., van't Veer, P., Eussen, S., van Dongen, M., Wijckmans-Duysens, N., & Harrington, J. M. (2017). A systematic review of methods to assess intake of sugar-sweetened beverages among healthy European adults and children: a DEDIPAC (DEterminants of DIet and Physical Activity) study. Public Health Nutrition, 20(4), 578-597. https://doi.org/10.1017/S1368980016002639
    • van Moorsel, D., Henry, R. M., Schaper, N. C., van Greevenbroek, M. M., van Rossum, E. F., 't Hart, L. M., Schalkwijk, C. G., van der Kallen, C. J., Dekker, J. M., Stehouwer, C. D., & Havekes, B. (2017). BclI Glucocorticoid Receptor Polymorphism in Relation to Arterial Stiffening and Cardiac Structure and Function: The Hoorn and CODAM Studies. American Journal of Hypertension, 30(3), 286-294. https://doi.org/10.1093/ajh/hpw196
    • den Biggelaar, L. J. C. J., Sep, S. J. S., Eussen, S. J. P. M., Mari, A., Ferrannini, E., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., & Dagnelie, P. C. (2017). Discriminatory ability of simple OGTT-based beta cell function indices for prediction of prediabetes and type 2 diabetes: the CODAM study. Diabetologia, 60(3), 432-441. https://doi.org/10.1007/s00125-016-4165-3
    • Simons, N., Isaacs, A., Koek, G. H., Kuc, S., Schaper, N. C., & Brouwers, M. C. G. J. (2017). PNPLA3, TM6SF2, and MBOAT7 Genotypes and Coronary Artery Disease. Gastroenterology, 152(4), 912-913. https://doi.org/10.1053/j.gastro.2016.12.020
    • Wouters, K., Gaens, K., Bijnen, M., Verboven, K., Jocken, J., Wetzels, S., Wijnands, E., Hansen, D., van Greevenbroek, M., Duijvestijn, A. M., Biessen, E. A. L., Blaak, E. E., Stehouwer, C. D. A., & Schalkwijk, C. G. (2017). Circulating classical monocytes are associated with CD11c(+) macrophages in human visceral adipose tissue. Scientific Reports, 7, Article 42665. https://doi.org/10.1038/srep42665
    • Wetzels, S., Wouters, K., Schalkwijk, C. G., Vanmierlo, T., & Hendriks, J. J. A. (2017). Methylglyoxal-Derived Advanced Glycation Endproducts in Multiple Sclerosis. International journal of molecular sciences, 18(2), Article 421. https://doi.org/10.3390/ijms18020421
    • Roest, A. A., Stoffers, J., Pijpers, E., Jansen, J., & Stassen, P. M. (2017). Ambulance patients with nondocumented sepsis have a high mortality risk: a retrospective study. European Journal of Emergency Medicine, 24(1), 36-43. https://doi.org/10.1097/MEJ.0000000000000302
    • Wachter, R., Halbach, M., Bakris, G. L., Bisognano, J. D., Haller, H., Beige, J., Kroon, A. A., Nadim, M. K., Lovett, E. G., Schafer, J. E., & de Leeuw, P. W. (2017). An exploratory propensity score matched comparison of second-generation and first-generation baroreflex activation therapy systems. Journal of the American Society of Hypertension, 11(2), 81-91. https://doi.org/10.1016/j.jash.2016.12.003
    • Riordan, F., Ryan, K., Perry, I. J., Schulze, M. B., Andersen, L. F., Geelen, A., van't Veer, P., Eussen, S., Dagnelie, P., Wijckmans-Duysens, N., & Harrington, J. M. (2017). A systematic review of methods to assess intake of fruits and vegetables among healthy European adults and children: a DEDIPAC (DEterminants of DIet and Physical Activity) study. Public Health Nutrition, 20(3), 417-448. https://doi.org/10.1017/S1368980016002366
    • van Bussel, F. C. G., Backes, W. H., van Veenendaal, T. M., Hofman, P. A. M., van Boxtel, M. P. J., Schram, M. T., Sep, S. J. S., Dagnelie, P. C., Schaper, N., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. F. A. (2017). Erratum: Functional Brain Networks Are Altered in Type 2 Diabetes and Prediabetes: Signs for Compensation of Cognitive Decrements? The Maastricht Study (vol 65, pg 2404, 2016). Diabetes, 66(2), 560. https://doi.org/10.2337/db17-er02a
    • Martens, R. J. H., Kooman, J. P., Stehouwer, C. D. A., Dagnelie, P. C., van der Kallen, C. J. H., Koster, A., Kroon, A. A., Leunissen, K. M. L., Nijpels, G., van der Sande, F. M., Schaper, N. C., Sep, S. J. S., van Boxtel, M. P. J., Schram, M. T., & Henry, R. M. A. (2017). Estimated GFR, Albuminuria, and Cognitive Performance: The Maastricht Study. American Journal of Kidney Diseases, 69(2), 179-191. https://doi.org/10.1053/j.ajkd.2016.04.017
    • van Bussel, B. C. T., van de Poll, M. C. G., Schalkwijk, C. G., & Bergmans, D. C. J. J. (2017). Increased Dicarbonyl Stress as a Novel Mechanism of Multi-Organ Failure in Critical Illness. International journal of molecular sciences, 18(2), Article 346. https://doi.org/10.3390/ijms18020346
    • De Clerck, E. E. B., Schouten, J. S. A. G., Berendschot, T. T. J. M., Beckers, H. J. M., Schaper, N. C., Schram, M. T., Stehouwer, C. D. A., & Webers, C. A. B. (2017). Loss of Temporal Peripapillary Retinal Nerve Fibers in Prediabetes or Type 2 Diabetes Without Diabetic Retinopathy: The Maastricht Study. Investigative Ophthalmology & Visual Science, 58(2), 1017-1027. https://doi.org/10.1167/iovs.16-19638
    • Barutta, F., Bruno, G., Matullo, G., Chaturvedi, N., Grimaldi, S., Schalkwijk, C., Stehouwer, C. D., Fuller, J. H., & Gruden, G. (2017). MicroRNA-126 and micro-/macrovascular complications of type 1 diabetes in the EURODIAB Prospective Complications Study. Acta Diabetologica, 54(2), 133-139. https://doi.org/10.1007/s00592-016-0915-4
    • van Iterson, M., van Zwet, E. W., Heijmans, B. T., 't Hoen, P. A. C., van Meurs, J., Jansen, R., Franke, L., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., van Greevenbroek, M. M. J., Stehouwer, C. D. A., van der Kallen, C. J. H., Schalkwijk, C. G., Wijmenga, C., Zhernakova, S., Tigchelaar, E. F., Eline Slagboom, P., ... BIOS Consortium (2017). Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution. Genome Biology, 18(1), Article 19. https://doi.org/10.1186/s13059-016-1131-9
    • van der Vorst, E. P. C., Theodorou, K., Wu, Y., Hoeksema, M. A., Goossens, P., Bursill, C. A., Aliyev, T., Huitema, L. F. A., Tas, S. W., Wolfs, I. M. J., Kuijpers, M. J. E., Gijbels, M. J., Schalkwijk, C. G., Koonen, D. P. Y., Abdollahi-Roodsaz, S., McDaniels, K., Wang, C.-C., Leitges, M., Lawrence, T., ... Donners, M. M. P. C. (2017). High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-kappa B/STAT1-IRF1 Signaling. Cell Metabolism, 25(1), 197-207. https://doi.org/10.1016/j.cmet.2016.10.013
    • Joosen, D. A. W. A., Zwietering, N. A., Bosch, M., & Stassen, P. M. (2017). Characteristics and outcome of acute medical admissions with hyponatremia: Even mild hyponatremia is associated with higher mortality. Acute Medicine, 16(4), 156-163. https://doi.org/10.52964/AMJA.0677
    • van Twist, D. J. L., van de laar, R. J. J. M., Brans, R. J. B., Refos, J. W. J., & Kroon, A. A. (2017). A 34-year-old man with back pain. Netherlands Journal of Medicine, 75(1), 45-46. http://www.njmonline.nl/article_ft.php?a=1809&d=1199&i=202
    • van Dooren, F. E. P., Pouwer, F., Schalkwijk, C. G., Sep, S. J. S., Stehouwer, C. D. A., Henry, R. M. A., Dagnelie, P. C., Schaper, N. C., van der Kallen, C. J. H., Koster, A., Denollet, J., Verhey, F. R. J., & Schram, M. T. (2017). Advanced Glycation End Product (AGE) Accumulation in the Skin is Associated with Depression: The Maastricht Study. Depression and Anxiety, 34(1), 59-67. https://doi.org/10.1002/da.22527
    • van Varik, B. J., Vossen, L. M., Rennenberg, R. J., Stoffers, H. E., Kessels, A. G., de Leeuw, P. W., & Kroon, A. A. (2017). Arterial stiffness and decline of renal function in a primary care population. Hypertension Research, 40(1), 73-78. https://doi.org/10.1038/hr.2016.113
    • Joris, P. J., Plat, J., Kusters, Y. H. A. M., Houben, A. J. H. M., Stehouwer, C. D. A., Schalkwijk, C. G., & Mensink, R. P. (2017). Diet-induced weight loss improves not only cardiometabolic risk markers but also markers of vascular function: a randomized controlled trial in abdominally obese men. American Journal of Clinical Nutrition, 105(1), 23-31. https://doi.org/10.3945/ajcn.116.143552
    • Bonder, M. J., Luijk, R., Zhernakova, D. V., Moed, M., Deelen, P., Vermaat, M., van Iterson, M., van Dijk, F., van Galen, M., Bot, J., Slieker, R. C., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., van Rooij, J., Lakenberg, N., Arindrarto, W., ... Franke, L. (2017). Disease variants alter transcription factor levels and methylation of their binding sites. Nature Genetics, 49(1), 131-138. https://doi.org/10.1038/ng.3721
    • Zhernakova, D. V., Deelen, P., Vermaat, M., van Iterson, M., van Galen, M., Arindrarto, W., van 't Hof, P., Mei, H., van Dijk, F., Westra, H.-J., Bonder, M. J., van Rooij, J., Verkerk, M., Jhamai, P. M., Moed, M., Kielbasa, S. M., Bot, J., Nooren, I., Pool, R., ... Franke, L. (2017). Identification of context-dependent expression quantitative trait loci in whole blood. Nature Genetics, 49(1), 139-145. https://doi.org/10.1038/ng.3737
    • van den Nouland, D. P. A., Brouwers, M. C. G. J., & Stassen, P. M. (2017). Prognostic value of plasma lactate levels in a retrospective cohort presenting at a university hospital emergency department. BMJ Open, 7(1), Article 011450. https://doi.org/10.1136/bmjopen-2016-011450
    • Pearce, K., Hatzinikolas, A., Moran, L., de Courten, M. P. J., Forbes, J., Scheijen, J. L. J. M., Schalkwijk, C. G., Walker, K., & de Courten, B. (2017). Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity. International Journal of Food Sciences and Nutrition, 68(8), 1021-1026. https://doi.org/10.1080/09637486.2017.1319468
    • Mitsides, N., Cornelis, T., Broers, N. J. H., Diederen, N. M. P., Brenchley, P., Heitink-ter Braak, N., van der Sande, F. M., Schalkwijk, C. G., Kooman, J. P., & Mitra, S. (2017). Inflammatory and Angiogenic Factors Linked to Longitudinal Microvascular Changes in Hemodialysis Patients Irrespective of Treatment Dose Intensity. Kidney & Blood Pressure Research, 43(5), 905-918. https://doi.org/10.1159/000485048
  • 2016
    • Dalem, J. V., Brouwers, M. C. G. J., Stehouwer, C. D. A., Krings, A., Leufkens, H. G. M., Driessen, J. H. M., Devries, F., & Burden, A. M. (2016). Het risico op hypoglykemieen bij sulfonylureum- derivaten ten opzichte van metformine in relatie tot nierfunctie en metabolietgroep. Pharmaceutisch Weekblad, 151(50), 37-41.
    • Uiterwijk, R., van Oostenbrugge, R. J., Huijts, M., De Leeuw, P. W., Kroon, A. A., & Staals, J. (2016). Total Cerebral Small Vessel Disease MRI Score Is Associated with Cognitive Decline in Executive Function in Patients with Hypertension. Frontiers in Aging Neuroscience, 8(DEC), Article 301. https://doi.org/10.3389/fnagi.2016.00301
    • Ras, R. T., Fuchs, D., Koppenol, W. P., Schalkwijk, C. G., Otten-Hofman, A., Garczarek, U., Greyling, A., Wagner, F., & Trautwein, E. A. (2016). Effect of a plant sterol-enriched spread on biomarkers of endothelial dysfunction and low-grade inflammation in hypercholesterolaemic subjects. Journal of Nutritional Science, 5, Article e44. https://doi.org/10.1017/jns.2016.40
    • Reynaert, N. L., Gopal, P., Rutten, E. P. A., Wouters, E. F. M., & Schalkwijk, C. G. (2016). Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to disease. International Journal of Biochemistry & Cell Biology, 81(Part B), 403-418. https://doi.org/10.1016/j.biocel.2016.06.016
    • Martens, R. J. H., Henry, R. M. A., Houben, A. J. H. M., van der Kallen, C. J. H., Kroon, A. A., Schalkwijk, C. G., Schram, M. T., Sep, S. J. S., Schaper, N. C., Dagnelie, P. C., Muris, D. M. J., Gronenschild, E. H. B. M., van der Sande, F. M., Leunissen, K. M. L., Kooman, J. P., & Stehouwer, C. D. A. (2016). Capillary Rarefaction Associates with Albuminuria: The Maastricht Study. Journal of the American Society of Nephrology, 27(12), 3748-3757. https://doi.org/10.1681/ASN.2015111219
    • Jansen, J., van Bussel, F. C. G., van de Haar, H. J., van Osch, M. J. P., Hofman, P. A. M., van Boxtel, M. P. J., van Oostenbrugge, R. J., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Backes, W. H. (2016). Cerebral blood flow, blood supply, and cognition in Type 2 Diabetes Mellitus. Scientific Reports, 6(1), Article 10. https://doi.org/10.1038/s41598-016-0003-6
    • Spauwen, P. J. J., Martens, R., Stehouwer, C. D. A., Verhey, F. R. J., Schram, M. T., Sep, S. J. S., van der Kallen, C. J. H., Dagnelie, P. C., Henry, R. M. A., Schaper, N. C., & van Boxtel, M. P. J. (2016). Lower verbal intelligence is associated with diabetic complications and slower walking speed in people with Type 2 diabetes: the Maastricht Study. Diabetic Medicine, 33(12), 1632–1639. https://doi.org/10.1111/dme.13105
    • Begieneman, M. P. V., Emmens, R. W., Rijvers, L., Woudstra, L., Paulus, W. J., Kubat, B., Vonk, A. B. A., van Rossum, A. C., Wouters, D., Zeerleder, S., van Ham, M., Schalkwijk, C. G., Niessen, H. W. M., & Krijnen, P. A. J. (2016). Myocardial infarction induces atrial inflammation that can be prevented by C1-esterase inhibitor. Journal of Clinical Pathology, 69(12), 1093-1099. https://doi.org/10.1136/jclinpath-2016-203639
    • Fokkens, B. T., Mulder, D. J., Nugteren, M. B., Schalkwijk, C. G., Scheijen, J. L., Smit, A. J., & Los, L. I. (2016). Surface Area of Detachment, Proliferative Vitreoretinopathy, and Pulse Pressure, but not AGEs, are Associated With Retinal Redetachment. Investigative Ophthalmology & Visual Science, 57(15), 6633-6638. https://doi.org/10.1167/iovs.16-20735
    • Sörensen, B., Houben, B., Berendschot, T. T. J. M., Schouten, J. S. A. G., Kroon, A. A., van der Kallen, C. J. H., Henry, R. M. A., Koster, A., Sep, S. J. S., Dagnelie, P. C., Schaper, N. C., Schram, M. T., & Stehouwer, C. D. A. (2016). Prediabetes and Type 2 Diabetes Are Associated With Generalized Microvascular Dysfunction The Maastricht Study. Circulation, 134(18), 1339-1352. https://doi.org/10.1161/CIRCULATIONAHA.116.023446
    • Nielen, J. T. H., Dagnelie, P. C., Emans, P., Veldhorst-Janssen, N., Lalmohamed, A., van Staa, T.-P., Boonen, A., van den Bemt, B., & de Vries, F. (2016). Safety and efficacy of new oral anticoagulants and low-molecular-weight heparins compared with aspirin in patients undergoing total knee and hip replacements. Pharmacoepidemiology and Drug Safety, 25(11), 1245-1252. https://doi.org/10.1002/pds.4089
    • Schutten, M. T. J., Houben, A. J. H. M., Kroon, A. A., Stehouwer, C. D. A., & de Leeuw, P. W. (2016). Aldosterone-Renin Ratio and Side-Selective Renal Perfusion in Essential Hypertension. American Journal of Hypertension, 29(11), 1311-1316. https://doi.org/10.1093/ajh/hpw077
    • Grassi, D., Draijer, R., Schalkwijk, C., Desideri, G., D'Angeli, A., Francavilla, S., Mulder, T., & Ferri, C. (2016). Black Tea Increases Circulating Endothelial Progenitor Cells and Improves Flow Mediated Dilatation Counteracting Deleterious Effects from a Fat Load in Hypertensive Patients: A Randomized Controlled Study. Nutrients, 8(11), Article UNSP 727. https://doi.org/10.3390/nu8110727
    • de Waard, E. A. C., Koster, A., Melai, T., van Geel, T. A., Henry, R. M. A., Schram, M. T., Dagnelie, P. C., van der Kallen, C. J., Sep, S. J. S., Stehouwer, C. D. A., Schaper, N. C., Köhler, S., Savelberg, H. H. C. M., Geusens, P. P. M. M., & van den Bergh, J. P. W. (2016). The association between glucose metabolism status, diabetes severity and a history of fractures and recent falls in participants of 50 years and older-the Maastricht Study. Osteoporosis International, 27(11), 3207-3216. https://doi.org/10.1007/s00198-016-3645-0
    • Janssen, E. P. C. J., Köhler, S., Stehouwer, C. D. A., Schaper, N. C., Dagnelie, P. C., Sep, S. J. S., Henry, R. M. A., van der Kallen, C. J. H., Verhey, F. R., & Schram, M. T. (2016). The Patient Health Questionnaire-9 as a Screening Tool for Depression in Individuals with Type 2 Diabetes Mellitus: The Maastricht Study. Journal of the American Geriatrics Society, 64(11), E201-E206. https://doi.org/10.1111/jgs.14388
    • Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Turtoi, A., Costanza, B., Smargiasso, N., Baiwir, D., Scheijen, J. L., Schalkwijk, C. G., Leenders, J., De Tullio, P., Bianchi, E., Thiry, M., Uchida, K., Spiegel, D. A., Cochrane, J. R., ... Bellahcene, A. (2016). Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis. Elife, 5(OCTOBER2016), Article e19375. https://doi.org/10.7554/elife.19375
    • Marsch, E., Demandt, J. A. F., Theelen, T. L., Tullemans, B. M. E., Wouters, K., Boon, M. R., van Dijk, T. H., Gijbels, M. J., Dubois, L. J., Meex, S. J. R., Mazzone, M., Hung, G., Fisher, E. A., Biessen, E. A. L., Daemen, M. J. A. P., Rensen, P. C. N., Carmeliet, P., Groen, A. K., & Sluimer, J. C. (2016). Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia. European Heart Journal, 37(39), 2993-2997. https://doi.org/10.1093/eurheartj/ehw156
    • Simons, N., Dekker, J. M., van Greevenbroek, M. M. J., Nijpels, G., 't Hart, L. M., van der Kallen, C. J. H., Schalkwijk, C. G., Schaper, N. C., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2016). A Common Gene Variant in Glucokinase Regulatory Protein Interacts With Glucose Metabolism on Diabetic Dyslipidemia: the Combined CODAM and Hoorn Studies. Diabetes Care, 39(10), 1811-1817. https://doi.org/10.2337/dc16-0153
    • Geijselaers, S. L. C., Sep, S. J. S., Schram, M. T., van Boxtel, M. P. J., van Sloten, T. T., Henry, R. M. A., Reesink, K. D., Kroon, A. A., Koster, A., Schaper, N. C., Dagnelie, P. C., van der Kallen, C. J. H., Biessels, G. J., & Stehouwer, C. D. A. (2016). Carotid stiffness is associated with impairment of cognitive performance in individuals with and without type 2 diabetes. The Maastricht Study. Atherosclerosis, 253, 186-193. https://doi.org/10.1016/j.atherosclerosis.2016.07.912
    • Mommersteeg, P. M. C., Schoemaker, R. G., Naude, P. J. W., Eisel, U. L. M., Garrelds, I. M., Schalkwijk, C. G., Westerhuis, B. W. J. J. M., Kop, W. J., & Denollet, J. (2016). Depression and markers of inflammation as predictors of all-cause mortality in heart failure. Brain Behavior and Immunity, 57, 144-150. https://doi.org/10.1016/j.bbi.2016.03.012