Roberto Lorusso

Professor

Prof. Roberto Lorusso studied medicine at the University of Milan, Italy and graduated in 1987 magna cum Laude. He worked at Maastricht UMC+ in 1990 at CTC research and in 1996 and 1997 at the academic Hospital of Leuven. In 1998, he successfully obtained his PhD degree at Maastricht University (thesis titled 'Cardiac reinforcement and assistance by electrically stimulated skeletal muscle').

Currently, Prof. Roberto Lorusso is staff member at the Department of Cardiothoracic Surgery at Maastricht UMC+, Director of the Extracorporeal Life Support (ECLS) Program, Full Professor of Cardiac Surgery and ECLS at the Maastricht University and CARIM. His research group is focussed on mechanical circulatory support, minimally invasive valve surgery, coronary surgery, cardiac valve disease, extracorporeal circulation, acute myocardial infarction complications, cardiac valve disease, preclinical and clinical research.

Prof. Roberto Lorusso won the Gasperis-Donatelli Prize in 1989, a Young Investigator Award in 1995 and the Lillehei Award in 1998 by the European Association for Cardio-Thoracic Surgery. He was Scientific Secretary of the Italian Society for Cardiac Surgery in 2007 and 2008, President of Euro-ELSO (2015-2017), and he is currently Editor-in-Chief of the Multi-Media Manual of Cardio-Thoracic Surgery as well as member of the ELSO Executive Committee.

He has almost 300 publications in PubMed, and has given more than 300 presentations at international meetings as invited speaker. He is Principal Investigator of international multicentre clinical studies and grant receiver from several funding bodies for clinical as well as pre-clinical investigations.

Department of Cardiothoracic surgery
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
Room number: D.2037
T: +31(0)43 387 60 32

2022
- Flynn, C. D., Morris, P., Manuel, L., Matteucci, M., Ronco, D., Massimi, G., Torchio, F., & Lorusso, R. (2022). Systematic review and meta-analysis of the mechanical complications of ischemic heart disease: papillary muscle rupture, left ventricle rupture and post-infarct ventricular septal defect. Annals of Cardiothoracic Surgery, 11(3), 195-209. https://doi.org/10.21037/acs-2022-ami-24
- Lorusso, R., Lo Coco, V., Ravaux, J. M., & Mariani, S. (2022). The use of mechanical circulatory support in post-acute myocardial infarction mechanical complications. Annals of Cardiothoracic Surgery, 11(3), 325-327. https://doi.org/10.21037/acs-2021-ami-21
- Lorusso, R., Calafiore, A. M., & Di Mauro, M. (2022). Acute infective endocarditis during COVID-19 pandemic time: The dark side of the moon. Journal of Cardiac Surgery, 37(5), 1168-1170. https://doi.org/10.1111/jocs.16281
- Ronco, D., Corazzari, C., Matteucci, M., Massimi, G., Di Mauro, M., Ravaux, J. M., Beghi, C., & Lorusso, R. (2022). Effects of concomitant coronary artery bypass grafting on early and late mortality in the treatment of post-infarction mechanical complications: a systematic review and meta-analysis. Annals of Cardiothoracic Surgery, 11(3), 210-225. https://doi.org/10.21037/acs-2021-ami-19
- Heuts, S., Adriaans, B. P., Kawczynski, M. J., Daemen, J. H. T., Natour, E., Lorusso, R., Schalla, S., Maessen, J. G., Wildberger, J. E., Jacobs, M. J., Rylski, B., & Bidar, E. (2022). Extending Aortic Replacement Beyond the Proximal Arch in Acute Type A Aortic Dissection: A Meta-Analysis of Short Term Outcomes and Long Term Actuarial Survival. European Journal of Vascular and Endovascular Surgery, 63(5), 674-687. https://doi.org/10.1016/j.ejvs.2021.12.045
- Willers, A., Swol, J., von Kuijk, S. M. J., Buscher, H., McQuilten, Z., ten Cate, H., Rycus, P. T., McKellar, S., Lorusso, R., & Tonna, J. E. (2022). HEROES V-V-HEmorRhagic cOmplications in Veno-Venous Extracorporeal life Support-Development and internal validation of multivariable prediction model in adult patients. Artificial Organs, 46(5), 932-952. https://doi.org/10.1111/aor.14148
- Torchio, F., Garatti, A., Ronco, D., Matteucci, M., Massimi, G., & Lorusso, R. (2022). Left ventricular pseudoaneurysm: the niche of post-infarction mechanical complications. Annals of Cardiothoracic Surgery, 11(3), 290-298. https://doi.org/10.21037/acs-2022-ami-25
- Lorusso, R., Ronco, D., Massimi, G., Di Mauro, M., Jiritano, F., & Matteucci, M. (2022). Managing and repairing ventricular free-wall rupture: the triple-patch technique. Annals of Cardiothoracic Surgery, 11(3), 346-348. https://doi.org/10.21037/acs-2021-ami-22
- Rahouma, M., Baudo, M., Shmushkevich, S., Chadow, D., Mohamed, A., Girardi, L., Gaudino, M., & Lorusso, R. (2022). Sex differences in primary malignant cardiac tumors: A multi-institutional cohort study from National Cancer Database. Journal of Cardiac Surgery, 37(5), 1275-1286. https://doi.org/10.1111/jocs.16359
- Matteucci, M., Ronco, D., Ravaux, J. M., Massimi, G., Di Mauro, M., Houterman, S., Maessen, J., Beghi, C., Severgnini, P., Lorusso, R., & Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration (2022). Surgical repair of post-infarction ventricular free-wall rupture in the Netherlands: data from a nationwide registry. Annals of Cardiothoracic Surgery, 11(3), 310-318. https://doi.org/10.21037/acs-2021-ami-10
- Massimi, G., Matteucci, M., Kowalewski, M., Ronco, D., Jiritano, F., Beghi, C., Severgnini, P., & Lorusso, R. (2022). Surgical treatment of post-infarction papillary muscle rupture: systematic review and meta-analysis. Annals of Cardiothoracic Surgery, 11(3), 252-260. https://doi.org/10.21037/acs-2021-ami-15
- Condello, I., Lorusso, R., Santarpino, G., Fiore, F., Nasso, G., & Speziale, G. (2022). Clinical Evaluation of Micro-Embolic Activity with Unexpected Predisposing Factors and Performance of Horizon AF PLUS during Cardiopulmonary Bypass. Membranes, 12(5), Article 465. https://doi.org/10.3390/membranes12050465
- Sala, A., Lorusso, R., & Alfieri, O. (2022). Isolated tricuspid regurgitation: A plea for early correction. International Journal of Cardiology, 353, 80-85. https://doi.org/10.1016/j.ijcard.2022.01.069
- D'Auria, F., Santo, D. F., Myat, A., Lorusso, R., Ravaux, J. M., Trivedi, U., & Hildick-Smith, D. (2022). Apical versus subclavian transcatheter aortic valve implantation: An 8-year United Kingdom analysis. Journal of Cardiac Surgery, 37(4), 978-984. https://doi.org/10.1111/jocs.16298
- Di Nardo, M., De Piero, M. E., Hoskote, A., Belohlavek, J., Lorusso, R., & EuroECMO neonatal and paediatric COVID-19 Working Group and EuroELSO Steering Committee (2022). Extracorporeal membrane oxygenation in children with COVID-19 and PIMS-TS during the second and third wave. Lancet child & adolescent health, 6(4), E14-E15. https://doi.org/10.1016/s2352-4642(22)00065-7
- Squiccimarro, E., Stasi, A., Lorusso, R., & Paparella, D. (2022). Narrative review of the systemic inflammatory reaction to cardiac surgery and cardiopulmonary bypass. Artificial Organs, 46(4), 568-577. https://doi.org/10.1111/aor.14171
- Wang, L., Yang, F., Zhang, S., Li, C., Du, Z., Rycus, P., Tonna, J. E., Alexander, P., Lorusso, R., Fan, E., Ogino, M., Brodie, D., Combes, A., Chen, Y.-S., Qiu, H., Peng, Z., Fraser, J. F., Shao, J., Jia, M., ... Hou, X. (2022). Percutaneous versus surgical cannulation for femoro-femoral VA-ECMO in patients with cardiogenic shock: Results from the Extracorporeal Life Support Organization Registry. Journal of Heart and Lung Transplantation, 41(4), 470-481. https://doi.org/10.1016/j.healun.2022.01.009
- Di Mauro, M., Bonalumi, G., Calafiore, A. M., & Lorusso, R. (2022). Valve endocarditis, to repair or not to repair, is that really the question?Journal of Cardiac Surgery, 37(4), 1016-1018. https://doi.org/10.1111/jocs.16232
- Condello, I., Lorusso, R., Santarpino, G., Di Bari, N., Fiore, F., Moscarelli, M., Calafiore, A. M., Speziale, G., & Nasso, G. (2022). Perioperative incidence of ECMO and IABP on 5901 mitral valve surgery procedures. Journal of Cardiothoracic Surgery, 17(1), Article 38. https://doi.org/10.1186/s13019-022-01790-1
- Sciatti, E., Mohseni, Z., Orabona, R., Mulder, E. G., Prefumo, F., Lorusso, R., Frusca, T., Spaanderman, M. E. A., & Ghossein-Doha, C. (2022). Inappropriate left ventricular mass after HELLP syndrome inappropriate LVM after HELLP syndrome. Pregnancy Hypertension: an international journal of women's cardiovascular health, 27, 16-22. https://doi.org/10.1016/j.preghy.2021.11.003
- Heuts, S., Makhoul, M., Mansouri, A. N., Taccone, F. S., Obeid, A., Belliato, M., Broman, L. M., Malfertheiner, M., Meani, P., Raffa, G. M., Delnoij, T., Maessen, J., Bolotin, G., & Lorusso, R. (2022). Defining and understanding the "extra-corporeal membrane oxygenation gap" in the veno-venous configuration: Timing and causes of death. Artificial Organs, 46(3), 349-361. https://doi.org/10.1111/aor.14058
- Matteucci, M., Ronco, D., Massimi, G., Di Mauro, M., & Lorusso, R. (2022). Le complicanze meccaniche dell’infarto miocardico acuto: dalla diagnosi al trattamento. Giornale Italiano di Cardiologia, 23(3), 190-199. https://doi.org/10.1714/3751.37338
- Ronco, D., Matteucci, M., Massimi, G., Di Mauro, M., & Lorusso, R. (2022). Postinfarction ventricular septal rupture repair: Is it just a matter of the surgical technique?Journal of Cardiac Surgery, 37(3), 524-525. https://doi.org/10.1111/jocs.16149
- Fischlein, T., Caporali, E., Asch, F. M., Vogt, F., Pollari, F., Folliguet, T., Kappert, U., Meuris, B., Shrestha, M. L., Roselli, E. E., Bonaros, N., Fabre, O., Corbi, P., Troise, G., Andreas, M., Pinaud, F., Pfeiffer, S., Kueri, S., Tan, E., ... Lorusso, R. (2022). Hemodynamic Performance of Sutureless vs. Conventional Bioprostheses for Aortic Valve Replacement: The 1-Year Core-Lab Results of the Randomized PERSIST-AVR Trial. Frontiers in Cardiovascular Medicine, 9, Article 844876. https://doi.org/10.3389/fcvm.2022.844876
- Moscarelli, M., Lorusso, R., Angelini, G. D., Di Bari, N., Paparella, D., Fattouch, K., Albertini, A., Nasso, G., Fiorentino, F., & Speziale, G. (2022). Sex-specific differences and postoperative outcomes of minimally invasive and sternotomy valve surgery. European Journal of Cardio-Thoracic Surgery, 61(3), 695-702. https://doi.org/10.1093/ejcts/ezab369
- Rahouma, M., Baudo, M., Shmushkevich, S., Chadow, D., Mohamed, A., Gaudino, M., & Lorusso, R. (2022). Association between insurance status and survival among patients with malignant cardiac tumours. British Journal of Surgery, 109(2), E24-E25. Article 423. https://doi.org/10.1093/bjs/znab423
- Meani, P., Lorusso, R., & Pappalardo, F. (2022). ECPella: Concept, Physiology and Clinical Applications. Journal of Cardiothoracic and Vascular Anesthesia, 36(2), 557-566. https://doi.org/10.1053/j.jvca.2021.01.056
- Ravaux, J. M., Van Kuijk, S. M. J., Di Mauro, M., Vernooy, K., Bidar, E., Van't Hof, A. W., Veenstra, L., Kats, S., Houterman, S., Maessen, J. G., Lorusso, R., & THI Registration Committee of The Netherlands Heart Registration (2022). Incidence and Predictors of Permanent Pacemaker Implantation after Transcatheter Aortic Valve Procedures: Data of The Netherlands Heart Registration (NHR). Journal of Clinical Medicine, 11(3), Article 560. https://doi.org/10.3390/jcm11030560
- Raasveld, S. J., Karami, M., van den Bergh, W. M., Lansink-Hartgring, A. O., van der Velde, F., Maas, J. J., van de Berg, P., de Haan, M., Lorusso, R., Delnoij, T. S. R., Miranda, D. D., Mandigers, L., Scholten, E., Overmars, M., Taccone, F. S., Brasseur, A., Dauwe, D. F., De Troy, E., Hermans, G., ... Vlaar, A. P. J. (2022). RBC Transfusion in Venovenous Extracorporeal Membrane Oxygenation: A Multicenter Cohort Study. Critical Care Medicine, 50(2), 224-234. https://doi.org/10.1097/CCM.0000000000005398
- Massimi, G., Ronco, D., De Bonis, M., Kowalewski, M., Formica, F., Russo, C. F., Sponga, S., Vendramin, I., Falcetta, G., Fischlein, T., Troise, G., Trumello, C., Actis Dato, G., Carrozzini, M., Shah, S. H., Coco, V. L., Villa, E., Scrofani, R., Torchio, F., ... Lorusso, R. (2022). Surgical treatment for post-infarction papillary muscle rupture: a multicentre study. European Journal of Cardio-Thoracic Surgery, 61(2), 469-476. https://doi.org/10.1093/ejcts/ezab469
- Santarpino, G., Lorusso, R., Moscarelli, M., Mikus, E., Wisniewski, K., Dell'Aquila, A. M., Margari, V., Carrozzo, A., Barbato, L., Fiorani, V., Lamarra, M., Fattouch, K., Squeri, A., Giannini, F., Marchese, A., Farahani, K., Gregorini, R., Comoglio, C., Martinelli, L., ... Speziale, G. (2022). Sutureless versus transcatheter aortic valve replacement: A multicenter analysis of "real-world" data. Journal of Cardiology, 79(1), 121-126. https://doi.org/10.1016/j.jjcc.2021.08.022
- Abrams, D., MacLaren, G., Lorusso, R., Price, S., Yannopoulos, D., Vercaemst, L., Belohlavek, J., Taccone, F. S., Aissaoui, N., Shekar, K., Garan, A. R., Uriel, N., Tonna, J. E., Jung, J. S., Takeda, K., Chen, Y. S., Slutsky, A. S., Combes, A., & Brodie, D. (2022). Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications. Intensive Care Medicine, 48(1), 1-15. https://doi.org/10.1007/s00134-021-06514-y
- Swol, J., Brodie, D., Willers, A., Zakhary, B., Belezzo, J., Shinar, Z., Weingart, S. D., Haft, J. W., Lorusso, R., & Peek, G. J. (2022). Human factors in ECLS - A keystone for safety and quality - A narrative review for ECLS providers. Artificial Organs, 46(1), 40-49. https://doi.org/10.1111/aor.14095
2021
- Mlcek, M., Meani, P., Cotza, M., Kowalewski, M., Raffa, G. M., Kuriscak, E., Popkova, M., Pilato, M., Arcadipane, A., Ranucci, M., Lorusso, R., & Belohlavek, J. (2021). Atrial Septostomy for Left Ventricular Unloading During Extracorporeal Membrane Oxygenation for Cardiogenic Shock Animal Model. Jacc-Cardiovascular Interventions, 14(24), 2698-2707. https://doi.org/10.1016/j.jcin.2021.09.011
- Di Mauro, M., Paparella, D., & Lorusso, R. (2021). Commentary: Left ventricular assist device infection. JTCVS open, 8, 416-417. https://doi.org/10.1016/j.xjon.2021.10.046
- Lorusso, R., Jiritano, F., Roselli, E., Shrestha, M., Folliguet, T., Meuris, B., Pollari, F., Fischlein, T., & PERSIST-AVR Investigators (2021). Perioperative platelet reduction after sutureless or stented valve implantation: results from the PERSIST-AVR controlled randomized trial. European Journal of Cardio-Thoracic Surgery, 60(6), 1359-1365. https://doi.org/10.1093/ejcts/ezab175
- Ravaux, J. M., Di Mauro, M., Vernooy, K., Kats, S., Mariani, S., Ronco, D., Dato, G. A., Simons, J., Van't Hof, A. W., Maessen, J. G., & Lorusso, R. (2021). Permanent pacemaker implantation following transcatheter aortic valve implantation using self-expandable, balloon-expandable, or mechanically expandable devices: a network meta-analysis. EP Europace, 23(12), 1998-2009. https://doi.org/10.1093/europace/euab209
- Caporali, E., Lorusso, R., Torre, T., Toto, F., Pozzoli, A., Pedrazzini, G., Demertzis, S., & Ferrari, E. (2021). The Aortic Annulus Stabilization Technique Prevents Paravalvular Leaks after Rapid Deployment Aortic Valve Implantation. Journal of Clinical Medicine, 10(24), Article 5776. https://doi.org/10.3390/jcm10245776
- Suverein, M. M., Shaw, D., Lorusso, R., Delnoij, T. S. R., Essers, B., Weerwind, P. W., Townend, D., van de Poll, M. C. G., & Maessen, J. G. (2021). Ethics of ECPR research. Resuscitation, 169, 136-142. https://doi.org/10.1016/j.resuscitation.2021.08.007
- Lorusso, R., Mariani, S., & Ravaux, J. M. (2021). Gently handling the acutely failing right ventricle ... at last!Interactive Cardiovascular and Thoracic Surgery, 33(5), 801-802. https://doi.org/10.1093/icvts/ivab248
- Sala, A., Lorusso, R., Bargagna, M., Ascione, G., Ruggeri, S., Meneghin, R., Schiavi, D., Buzzatti, N., Trumello, C., Monaco, F., Agricola, E., Alfieri, O., Castiglioni, A., & De Bonis, M. (2021). Isolated tricuspid valve surgery: first outcomes report according to a novel clinical and functional staging of tricuspid regurgitation. European Journal of Cardio-Thoracic Surgery, 60(5), 1124-1130. https://doi.org/10.1093/ejcts/ezab228
- Lorusso, R., Ravaux, J. M., & Mariani, S. (2021). Left ventricular assist devices and right ventricular failure prediction: Quo Vadis?Interactive Cardiovascular and Thoracic Surgery, 33(5), 793-794. https://doi.org/10.1093/icvts/ivab208
- Di Mauro, M., Calafiore, A. M., & Lorusso, R. (2021). All roads lead to Rome, but some are safer. Journal of Cardiac Surgery, 36(11), 4320-4321. https://doi.org/10.1111/jocs.15956
- Ravaux, J. M., Mariani, S., & Lorusso, R. (2021). Predictors of permanent pacemaker implantation following surgical aortic valve replacement: Letter to the editor-Reply. Journal of Cardiac Surgery, 36(11), 4444-4444. https://doi.org/10.1111/jocs.15899
- Ronco, D., Matteucci, M., Kowalewski, M., De Bonis, M., Formica, F., Jiritano, F., Fina, D., Folliguet, T., Bonaros, N., Russo, C. F., Sponga, S., Vendramin, I., De Vincentiis, C., Ranucci, M., Suwalski, P., Falcetta, G., Fischlein, T., Troise, G., Villa, E., ... Lorusso, R. (2021). Surgical Treatment of Postinfarction Ventricular Septal Rupture. Jama network open, 4(10), Article e2128309. https://doi.org/10.1001/jamanetworkopen.2021.28309
- Heinsar, S., Jung, J. S., Colombo, S. M., Rozencwajg, S., Wildi, K., Sato, K., Ainola, C., Wang, X. M., Abbate, G., Sato, N., Dyer, W. B., Livingstone, S. A., Pimenta, L. P., Bartnikowski, N., Bouquet, M. J. P., Passmore, M., Vidal, B., Palmieri, C., Reid, J. D., ... Fraser, J. F. (2021). An innovative ovine model of severe cardiopulmonary failure supported by veno-arterial extracorporeal membrane oxygenation. Scientific Reports, 11(1), Article 20458. https://doi.org/10.1038/s41598-021-00087-y
- Gaudino, M., Sandner, S., Di Giammarco, G., Di Franco, A., Arai, H., Asai, T., Bakaeen, F., Doenst, T., Fremes, S. E., Glineur, D., Kieser, T. M., Lawton, J. S., Lorusso, R., Patel, N., Puskas, J. D., Tatoulis, J., Taggart, D. P., Vallely, M., & Ruel, M. (2021). The Use of Intraoperative Transit Time Flow Measurement for Coronary Artery Bypass Surgery Systematic Review of the Evidence and Expert Opinion Statements. Circulation, 144(14), 1160-1171. https://doi.org/10.1161/circulationaha.121.054311
- Barbaro, R. P., MacLaren, G., Boonstra, P. S., Combes, A., Agerstrand, C., Annich, G., Diaz, R., Fan, E., Hryniewicz, K., Lorusso, R., Paden, M. L., Stead, C. M., Swol, J., Iwashyna, T. J., Slutsky, A. S., Brodie, D., & Extracorporeal Life Support Organization (2021). Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry. Lancet, 398(10307), 1230-1238. https://doi.org/10.1016/S0140-6736(21)01960-7
- Sciatti, E., Mohseni, Z., Orabona, R., Mulder, E. G., Prefumo, F., Lorusso, R., Frusca, T., Ghossein-Doha, C., & Spaanderman, M. E. A. (2021). Maternal myocardial dysfunction after hemolysis, elevated liver enzymes, and low platelets syndrome: a speckle-tracking study. Journal of Hypertension, 39(10), 1956-1963. https://doi.org/10.1097/HJH.0000000000002901
- Jiritano, F., Fina, D., Lorusso, R., ten Cate, H., Kowalewski, M., Matteucci, M., Serra, R., Mastroroberto, P., & Serraino, G. F. (2021). Systematic review and meta-analysis of the clinical effectiveness of point-of-care testing for anticoagulation management during ECMO. Journal of Clinical Anesthesia, 73, Article 110330. https://doi.org/10.1016/j.jclinane.2021.110330

Overview

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Roberto Lorusso

Professor