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ERC Advanced Grant awarded to Prof. Andy Baker

ERC Advanced Grant awarded to Prof. Andy Baker

15 April 2024

Prof. Andy Baker (Dept of Pathology) has been awarded a European Research Council (ERC) Advanced Grant of €2,5M for his research project PolymiRize: Poly-miRNA targeting to prevent and reverse complex tissue remodelling after acute cardiovascular events'.

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Longer and better lives for patients with atrial fibrillation

Longer and better lives for patients with atrial fibrillation

15 April 2024

An international panel of experts published recommendations to improve management of atrial fibrillation (AF).

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Carim Maastricht
Carim Maastricht

Vanessa van Empel

Associate professor

Dr Vanessa van Empel studied Medicine at the University of Maastricht. During her studies, she started her PhD on the topic heart failure. She obtained her PhD from the University of Utrecht in 2007. Subsequently she started her training as a cardiologist at the Maastricht University Medical Centre. After finishing her cardiology training in 2011, Vanessa was rewarded the ICIN fellowship, which enabled her to do a post-doctoral fellowship at the Alfred Hospital in Melbourne, Australia, where she gained more expertise in the field of heart failure with preserved ejection fraction (HFpEF). She now is a staff member at the Maastricht UMC+ with an expertise in heart failure, and heart failure with preserved ejection fraction specifically.

Her clinical work and research has been dedicated to HFpEF. She initiated the HFpEF clinic in Maastricht, which started in 2015, and is responsible for the Maastricht HFpEF cohort. She obtained a grant 'Vrouwelijk Hartfalen' from the Health Foundation Limburg together with Prof. Blanche Schroen, is co-PI on the CVON project Early detection of HFpEF and is project leader of the CVON SHE-PREDICT-HF, which studies sex differences in HFpEF. These projects allow her to continue her research on HFpEF with special focus on cardiovascular imaging, biomarkers and microvascular dysfunction.

Vanessa-van-empel

Department of Cardiology
P. Debeyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: Maastricht UMC+ level 3
T: +31(0)43 387 70 95

  • 2024
    • Dib, M.-J., Levin, M. G., Zhao, L., Diab, A., Wang, Z., Ebert, C., Salman, O., Azzo, J. D., Gan, S., Zamani, P., Cohen, J. B., Gill, D., Burgess, S., Zagkos, L., van Empel, V., Richards, A. M., Doughty, R., Rietzschel, E. R., Kammerhoff, K., ... Chirinos, J. A. (2024). Proteomic Associations of Adverse Outcomes in Human Heart Failure. Journal of the American Heart Association, 13(5), Article e031154. https://doi.org/10.1161/JAHA.123.031154
    • Tubben, A., Tingen, H. S. A., Prakken, N. H. J., van Empel, V. P. M., Gorter, T. M., Meems, L. M. G., Manintveld, O. C., Rienstra, M., Tieleman, R. G., Glaudemans, A. W. J. M., van Veldhuisen, D. J., Slart, R. H. J. A., Nienhuis, H. L. A., & van der Meer, P. (2024). Prevalence of wild-type transthyretin amyloidosis in a prospective heart failure cohort with preserved and mildly reduced ejection fraction: Results of the Amylo-VIP-HF study. European journal of heart failure. Advance online publication. https://doi.org/10.1002/ejhf.3186
    • Azzo, J. D., Dib, M.-J., Zagkos, L., Zhao, L., Wang, Z., Chang, C.-P., Ebert, C., Salman, O., Gan, S., Zamani, P., Cohen, J. B., van Empel, V., Richards, A. M., Javaheri, A., Mann, D. L., Rietzschel, E. R., Schafer, P. H., Seiffert, D. A., Gill, D., ... Chirinos, J. A. (2024). Proteomic Associations of NT-proBNP (N-Terminal Pro-B-Type Natriuretic Peptide) in Heart Failure With Preserved Ejection Fraction. Circulation-Heart Failure, 17(2), Article e011146. https://doi.org/10.1161/CIRCHEARTFAILURE.123.011146
    • Clephas, P. R. D., Malgie, J., Schaap, J., Koudstaal, S., Emans, M., Linssen, G. C. M., de Boer, G. A., van Heerebeek, L., Borleffs, C. J. W., Manintveld, O. C., van Empel, V., van Wijk, S., van den Heuvel, M., da Fonseca, C., Damman, K., van Ramshorst, J., van Kimmenade, R., van de Ven, A. R. T., Tio, R. A., ... Brugts, J. J. (2024). Guideline implementation, drug sequencing, and quality of care in heart failure: design and rationale of TITRATE-HF. Esc heart failure, 11(1), 550-559. https://doi.org/10.1002/ehf2.14604
    • Nebhwani, M., Chaibekava, K., Achten, A., Oerlemans, M. I. F. J., Michels, M., van der Meer, P., Nienhuis, H. L. A., Weerts, J., van Empel, V., Rocca, H. P. B. L., Wijk, S. S. V., van der Pol, J., & Knackstedt, C. (2024). Detection of cardiac amyloidosis on routine bone scintigraphy: an important gatekeeper role for the nuclear medicine physician. International Journal of Cardiovascular Imaging. Advance online publication. https://doi.org/10.1007/s10554-024-03085-z
    • Adamo, M., Chioncel, O., Pagnesi, M., Bayes-Genis, A., Abdelhamid, M., Anker, S. D., Antohi, E.-L., Badano, L., Ben Gal, T., Böhm, M., Delgado, V., Dreyfus, J., Faletra, F. F., Farmakis, D., Filippatos, G., Grapsa, J., Gustafsson, F., Hausleiter, J., Jaarsma, T., ... Metra, M. (2024). Epidemiology, Pathophysiology, Diagnosis and Management of Chronic Right-Sided Heart Failure and Tricuspid Regurgitation. A clinical consensus statement of the Heart Failure Association (HFA) and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC. European journal of heart failure, 26(1), 18-33. https://doi.org/10.1002/ejhf.3106
    • Litwin, S. E., Komtebedde, J., Seidler, T., Borlaug, B. A., Winkler, S., Solomon, S. D., Eicher, J.-C., Mazimba, S., Khawash, R., Sverdlov, A. L., Hummel, S. L., Bugger, H., Boenner, F., Hoendermis, E., Cikes, M., Demers, C., Silva, G., van Empel, V., Starling, R., ... REDUCE LAP-HF investigators and research staff (2024). Obesity in Heart Failure with Preserved Ejection Fraction: Insights from the REDUCE LAP-HF II Trial. European journal of heart failure, 26(1), 177-189. https://doi.org/10.1002/ejhf.3092
  • 2023
    • Knackstedt, C., Ramaekers, B., Schummers, G., Schreckenberg, M., Faessen, J., Marx, N., Becker, M., Sanders-van Wijk, S., van Empel, V., Norra, C., Kunert, H. J., Brunner-La Rocca, H.-P., & PsychEcho study group (2023). Influence of Individual Personality Traits of the Reader on Visual Assessment of Left Ventricular Ejection Fraction: Another Reason to Abandon Visual Assessment. Journal of the American Society of Echocardiography, 36(12), 1332-1335. https://doi.org/10.1016/j.echo.2023.08.015
    • Potjewijd, J., Tobal, R., Boomars, K. A., van Empel, V. V. P. M., de Vries, F., Damoiseaux, J. G. M. C., Schurgers, L. J., & van Paassen, P. (2023). Plasma Dephosphorylated-Uncarboxylated Matrix Gla-Protein in Systemic Sclerosis Patients: Biomarker Potential for Vascular Calcification and Inflammation. Diagnostics, 13(23), Article 3526. https://doi.org/10.3390/diagnostics13233526
    • Weerts, J., Amin, H., Barandiarán Aizpurua, A., Gevaert, A. B., Handoko, M. L., Dauw, J., Tun, H. N., Rommel, K.-P., Verbrugge, F. H., Kresoja, K.-P., Sanders-van Wijk, S., Brunner-La Rocca, H.-P., Bayés-Genís, A., Lumens, J., Knackstedt, C., & van Empel, V. P. M. (2023). Webtool to enhance the accuracy of diagnostic algorithms for HFpEF: a prospective cross-over study. Esc heart failure, 10(6), 3493 - 3503. https://doi.org/10.1002/ehf2.14525
    • Kerstens, T. P., Weerts, J., van Dijk, A. P. J., Weijers, G., Knackstedt, C., Eijsvogels, T. M. H., Oxborough, D., van Empel, V. P. M., & Thijssen, D. H. J. (2023). Association of left ventricular strain-volume loop characteristics with adverse events in patients with heart failure with preserved ejection fraction. European Heart Journal Cardiovascular Imaging, 24(9), 1168-1176. https://doi.org/10.1093/ehjci/jead117
    • Raafs, A. G., Adriaans, B. P., Henkens, M. T. H. M., Verdonschot, J. A. J., Abdul Hamid, M. A., Díez, J., Knackstedt, C., van Empel, V. P. M., Brunner-La Rocca, H. P., González, A., Wildberger, J. E., Heymans, S. R. B., & Hazebroek, M. R. (2023). Biomarkers of Collagen Metabolism Are Associated with Left Ventricular Function and Prognosis in Dilated Cardiomyopathy: A Multi-Modal Study. Journal of Clinical Medicine, 12(17), Article 5695. https://doi.org/10.3390/jcm12175695
    • Canto, E. D., van Deursen, L., Hoek, A. G., Elders, P. J. M., den Ruijter, H. M., van der Velden, J., van Empel, V., Serné, E. H., Eringa, E. C., & Beulens, J. W. J. (2023). Microvascular endothelial dysfunction in skin is associated with higher risk of heart failure with preserved ejection fraction in women with type 2 diabetes: the Hoorn Diabetes Care System Cohort. Cardiovascular Diabetology, 22(1), Article 234. https://doi.org/10.1186/s12933-023-01935-z
    • Gorter, T. M., van Veldhuisen, D. J., Mulder, B. A., Arita, V. A. A. A., van Empel, V. P. M., Manintveld, O. C., Tieleman, R. G., Maass, A. H., Vernooy, K., van Gelder, I. C., & Rienstra, M. (2023). Prevalence and Incidence of Atrial Fibrillation in Heart Failure with Mildly Reduced or Preserved Ejection Fraction: (Additive) Value of Implantable Loop Recorders. Journal of Clinical Medicine, 12(11), Article 3682. https://doi.org/10.3390/jcm12113682
    • Kerstens, T. P., Weerts, J., van Dijk, A. P. J., Weijers, G., Knackstedt, C., Eijsvogels, T. M. H., Oxborough, D., van Empel, V. P. M., & Thijssen, D. H. J. (2023). Left ventricular strain-volume loops and diastolic dysfunction in suspected heart failure with preserved ejection fraction. International Journal of Cardiology, 378(1), 144-150. https://doi.org/10.1016/j.ijcard.2023.01.084
    • Knackstedt, C., Schummers, G., Schroder, J., Marx, N., Lumens, J., Sanders-van Wijk, S., Ramaekers, B., Becker, M., van Empel, V., Brunner-La Rocca, H. P., & PsychEcho study group (2023). A graphical analysis of aspects contributing to the spreading of measurements of left ventricular function. International Journal of Cardiovascular Imaging, 39(5), 915-927. https://doi.org/10.1007/s10554-023-02796-z
    • Luo, H., Weerts, J., Bekkers, A., Achten, A., Lievens, S., Smeets, K., van Empel, V., Delhaas, T., & Prinzen, F. W. (2023). Association between phonocardiography and echocardiography in heart failure patients with preserved ejection fraction. European Heart Journal - Digital Health, 4(1), 4-11. https://doi.org/10.1093/ehjdh/ztac073
  • 2022
    • Remmelzwaal, S., van Oort, S., Handoko, M. L., van Empel, V., Heymans, S. R. B., & Beulens, J. W. J. (2022). Inflammation and heart failure: a two-sample Mendelian randomization study. Journal of Cardiovascular Medicine, 23(11), 728-735. https://doi.org/10.2459/JCM.0000000000001373
    • Raafs, A. G., Adriaans, B. P., Henkens, M. T. H. M., Verdonschot, J. A. J., Ramaekers, M. J. F. G., Gommers, S., Hamid, M. A. A., Schalla, S., Knackstedt, C., van Empel, V. P. M., Hans-Peter, B., Wildberger, J. E., Bekkers, S. C. A. M., & Hazebroek, M. R. (2022). Myocardial Fibrosis Assessment Using T1 and ECV Mapping With Histologic Validation in Chronic Dilated Cardiomyopathy. JACC-Cardiovascular Imaging, 15(10), 1828-1830. https://doi.org/10.1016/j.jcmg.2022.05.002
    • van der Velden, R. M. J., Hermans, A. N. L., Pluymaekers, N. A. H. A., Gawalko, M., Elliott, A., Hendriks, J. M., Franssen, F. M. E., Slats, A. M., van Empel, V. P. M., Van Gelder, I. C., Thijssen, D. H. J., Eijsvogels, T. M. H., Leue, C., Crijns, H. J. G. M., Linz, D., & Simons, S. O. (2022). Dyspnea in patients with atrial fibrillation: Mechanisms, assessment and an interdisciplinary and integrated care approach. IJC Heart and Vasculature, 42, Article 101086. https://doi.org/10.1016/j.ijcha.2022.101086
    • Javaheri, A., Diab, A., Zhao, L., Qian, C., Cohen, J. B., Zamani, P., Kumar, A., Wang, Z., Ebert, C., Maranville, J., Kvikstad, E., Basso, M., van Empel, V., Richards, A. M., Doughty, R. N., Rietzschel, E., Kammerhoff, K., Gogain, J., Schafer, P., ... Chirinos, J. A. (2022). Proteomic Analysis of Effects of Spironolactone in Heart Failure With Preserved Ejection Fraction. Circulation-Heart Failure, 15(9), 827-837. Article e009693. https://doi.org/10.1161/CIRCHEARTFAILURE.121.009693
    • Henkens, M. T. H. M., Martinez, H. L., Weerts, J., Sammani, A., Raafs, A. G., Verdonschot, J. A. J., van de Leur, R. R., Sikking, M. A., Stroeks, S., van Empel, V. P. M., Brunner-La Rocca, H. P., van Stipdonk, A. M. W., Farmakis, D., Hazebroek, M. R., Vernooy, K., Bayes-de-Luna, A., Asselbergs, F. W., Bayes-Genis, A., & Heymans, S. R. B. (2022). Interatrial Block Predicts Life-Threatening Arrhythmias in Dilated Cardiomyopathy. Journal of the American Heart Association, 11(14), Article e025473. https://doi.org/10.1161/JAHA.121.025473
    • Verhaert, D. V. M., Linz, D., Chaldoupi, S. M., Westra, S. W., den Uijl, D. W., Philippens, S., Kerperien, M., Habibi, Z., Vorstermans, B., ter Bekke, R. M. A., Beukema, R. J., Evertz, R., Hemels, M. E. W., Luermans, J. G. L. M., Manusama, R., Lankveld, T. A. R., van der Heijden, C. A. J., Bidar, E., Hermans, B. M., ... Schotten, U. (2022). Rationale and Design of the ISOLATION Study: A Multicenter Prospective Cohort Study Identifying Predictors for Successful Atrial Fibrillation Ablation in an Integrated Clinical Care and Research Pathway. Frontiers in Cardiovascular Medicine, 9, Article 879139. https://doi.org/10.3389/fcvm.2022.879139
    • Weerts, J., Mourmans, S. G. J., Eringa, E., & van Empel, V. P. M. (2022). Improving insights into the heterogeneous HFpEF syndrome through microvascular research. Journal of Molecular and Cellular Cardiology, 167, 106-108. https://doi.org/10.1016/j.yjmcc.2022.04.001
    • Henkens, M. T. H. M., van Ommen, A. M., Remmelzwaal, S., Valstar, G. B., Wang, P., Verdonschot, J. A. J., Hazebroek, M. R., Hofstra, L., Empel, V. P. M., Beulens, J. W. J., Ruijter, H. M., & Heymans, S. R. B. (2022). The HFA-PEFF score identifies 'early-HFpEF' phenogroups associated with distinct biomarker profiles. Esc heart failure, 9(3), 2032-2036. https://doi.org/10.1002/ehf2.13861
    • Henkens, M. T. H. M., Weerts, J., Verdonschot, J. A. J., Raafs, A. G., Stroeks, S., Sikking, M. A., Amin, H., Mourmans, S. G. J., Geraeds, C. B. G., Sanders-van Wijk, S., Aizpurua, A. B., Uszko-Lencer, N. H. M. K., Krapels, I. P. C., Wolffs, P. F. G., Brunner, H. G., Leeuwen, R. E. W., Verhesen, W., Schalla, S. M., van Stipdonk, A. W. M., ... Heymans, S. R. B. (2022). Improving diagnosis and risk stratification across the ejection fraction spectrum: the Maastricht Cardiomyopathy registry. Esc heart failure, 9(2), 1463-1470. https://doi.org/10.1002/ehf2.13833
    • van Woerden, G., van Veldhuisen, D. J., Gorter, T. M., Ophuis, B., Saucedo-Orozco, H., van Empel, V. P. M., Willems, T. P., Geelhoed, B., Rienstra, M., & Westenbrink, B. D. (2022). The value of echocardiographic measurement of epicardial adipose tissue in heart failure patients. Esc heart failure, 9(2), 953-957. https://doi.org/10.1002/ehf2.13828
    • van Woerden, G., van Veldhuisen, D. J., Manintveld, O. C., van Empel, V. P. M., Willems, T. P., de Boer, R. A., Rienstra, M., Westenbrink, B. D., & Gorter, T. M. (2022). Epicardial Adipose Tissue and Outcome in Heart Failure With Mid-Range and Preserved Ejection Fraction. Circulation-Heart Failure, 15(3), Article 009238. https://doi.org/10.1161/CIRCHEARTFAILURE.121.009238
    • Weerts, J., Mourmans, S. G. J., Barandiaran Aizpurua, A., Schroen, B. L. M., Knackstedt, C., Eringa, E., Houben, A. J. H. M., & van Empel, V. P. M. (2022). The Role of Systemic Microvascular Dysfunction in Heart Failure with Preserved Ejection Fraction. Biomolecules, 12(2), Article 278. https://doi.org/10.3390/biom12020278
    • van Empel, E., De Vlieg, R. A., Harling, G., Marcus, M. E., Kahn, K., Barnighausen, T. W., Montana, L., Choko, A. T., & Manne-Goehler, J. (2022). Reaching for the 'first 95': a cross-country analysis of HIV self-testing in nine countries in sub-Saharan Africa. Aids, 36(2), 297-304. https://doi.org/10.1097/qad.0000000000003106
    • van Woerden, G., van Veldhuisen, D. J., Gorter, T. M., Willems, T. P., van Empel, V. P. M., Peters, A., Pundziute, G., Op den Akker, J. W., Rienstra, M., & Westenbrink, B. D. (2022). The clinical and prognostic value of late Gadolinium enhancement imaging in heart failure with mid-range and preserved ejection fraction. Heart and Vessels, 37(2), 273-281. https://doi.org/10.1007/s00380-021-01910-2
    • Dal Canto, E., Remmelzwaal, S., van Ballegooijen, A. J., Handoko, M. L., Heymans, S., van Empel, V., Paulus, W. J., Nijpels, G., Elders, P., & Beulens, J. W. J. (2022). Diagnostic value of echocardiographic markers for diastolic dysfunction and heart failure with preserved ejection fraction. Heart Failure Reviews, 27(1), 207-218. https://doi.org/10.1007/s10741-020-09985-1
    • Weerts, J., Barandiarán Aizpurua, A., Henkens, M. T. H. M., Lyon, A., van Mourik, M. J. W., van Gemert, M. R. A. A., Raafs, A., Sanders-van Wijk, S., Bayés-Genís, A., Heymans, S. R. B., Crijns, H. J. G. M., Brunner-La Rocca, H.-P., Lumens, J., van Empel, V. P. M., & Knackstedt, C. (2022). The prognostic impact of mechanical atrial dysfunction and atrial fibrillation in heart failure with preserved ejection fraction. European Heart Journal Cardiovascular Imaging, 23(1), 74-84. https://doi.org/10.1093/ehjci/jeab222
  • 2021
    • Tobal, R., Potjewijd, J., van Empel, V. P. M., Ysermans, R., Schurgers, L. J., Reutelingsperger, C. P., Damoiseaux, J. G. M. C., & van Paassen, P. (2021). Vascular Remodeling in Pulmonary Arterial Hypertension: The Potential Involvement of Innate and Adaptive Immunity. Frontiers in medicine, 8, Article 806899. https://doi.org/10.3389/fmed.2021.806899
    • Remmelzwaal, S., Beulens, J. W. J., Elders, P. J. M., Stehouwer, C. D. A., Handoko, M. L., Appelman, Y., van Empel, V., Heymans, S. R. B., & van Ballegooijen, A. J. (2021). Sex-specific associations of body composition measures with cardiac function and structure after 8 years of follow-up. Scientific Reports, 11(1), Article 21046. https://doi.org/10.1038/s41598-021-00541-x
    • Verdonschot, J. A. J., Henkens, M. T. H. M., Wang, P., Schummers, G., Raafs, A. G., Krapels, I. P. C., van Empel, V., Heymans, S. R. B., Brunner-La Rocca, H.-P., & Knackstedt, C. (2021). A global longitudinal strain cut-off value to predict adverse outcomes in individuals with a normal ejection fraction. Esc heart failure, 8(5), 4343-4345. https://doi.org/10.1002/ehf2.13465
    • Raafs, A., Verdonschot, J., Ferreira, J. P., Wang, P., Collier, T., Henkens, M., Bjorkman, J., Boccanelli, A., Clark, A. L., Delles, C., Diez, J., Gonzalez, A., Girerd, N., Jukema, J. W., Pinet, F., Rossignol, P., Thum, T., Vodovar, N., de Boer, R. A., ... Heymans, S. (2021). Identification of sex-specific biomarkers predicting new-onset heart failure. Esc heart failure, 8(5), 3512-3520. https://doi.org/10.1002/ehf2.13476
    • van Woerden, G., van Veldhuisen, D. J., Gorter, T. M., van Empel, V. P. M., Hemels, M. E. W., Hazebroek, E. J., van Veldhuisen, S. L., Willems, T. P., Rienstra, M., & Westenbrink, B. D. (2021). Importance of epicardial adipose tissue localization using cardiac magnetic resonance imaging in patients with heart failure with mid-range and preserved ejection fraction. Clinical Cardiology, 44(7), 987-993. https://doi.org/10.1002/clc.23644
    • Uijl, A., Veenis, J. F., Brunner-La Rocca, H. P., van Empel, V., Linssen, G. C. M., Asselbergs, F. W., van der Lee, C., Eurlings, L. W. M., Kragten, H., Al-Windy, N. Y. Y., van der Spank, A., Koudstaal, S., Brugts, J. J., & Hoes, A. W. (2021). Clinical profile and contemporary management of patients with heart failure with preserved ejection fraction: results from the CHECK-HF registry. Netherlands Heart Journal, 29(7-8), 370-376. https://doi.org/10.1007/s12471-020-01534-7
    • Uijl, A., Savarese, G., Vaartjes, I., Dahlstrom, U., Brugts, J. J., Linssen, G. C. M., van Empel, V., Brunner-La Rocca, H. P., Asselbergs, F. W., Lund, L. H., Hoes, A. W., & Koudstaal, S. (2021). Identification of distinct phenotypic clusters in heart failure with preserved ejection fraction. European journal of heart failure, 23(6), 973-982. https://doi.org/10.1002/ejhf.2169
    • Raafs, A. G., Verdonschot, J. A. J., Henkens, M. T. H. M., Adriaans, B. P., Wang, P., Derks, K., Abdul Hamid, M. A., Knackstedt, C., van Empel, V. P. M., Diez, J., Brunner-La Rocca, H.-P., Brunner, H. G., Gonzalez, A., Bekkers, S. C. A. M., Heymans, S. R. B., & Hazebroek, M. R. (2021). The combination of carboxy-terminal propeptide of procollagen type I blood levels and late gadolinium enhancement at cardiac magnetic resonance provides additional prognostic information in idiopathic dilated cardiomyopathy - A multilevel assessment of myocardial fibrosis in dilated cardiomyopathy. European journal of heart failure, 23(6), 933-944. https://doi.org/10.1002/ejhf.2201
    • Remmelzwaal, S., Beulens, J. W. J., Elders, P. J. M., Stehouwer, C. D. A., Zhang, Z., Handoko, M. L., Appelman, Y., van Empel, V., Heymans, S. R. B., Thijs, L., Staessen, J. A., & van Ballegooijen, A. J. (2021). Sex differences in the longitudinal relationship of low-grade inflammation and echocardiographic measures in the Hoorn and FLEMENGHO Study. PLOS ONE, 16(5), Article e0251148. https://doi.org/10.1371/journal.pone.0251148
    • Sanders-van Wijk, S., Barandiaran Aizpurua, A., Brunner-La Rocca, H.-P., Henkens, M. T. H. M., Weerts, J., Knackstedt, C., Uszko-Lencer, N., Heymans, S., & van Empel, V. (2021). The HFA-PEFF and H2FPEF scores largely disagree in classifying patients with suspected heart failure with preserved ejection fraction. European journal of heart failure, 23(5), 838-840. https://doi.org/10.1002/ejhf.2019
    • Barandiarán Aizpurua, A., Sanders-van Wijk, S., Brunner-La Rocca, H. P., Henkens, M. T. H. M., Weerts, J., Spanjers, M. H. A., Knackstedt, C., & van Empel, V. P. M. (2021). Iron deficiency impacts prognosis but less exercise capacity in heart failure with preserved ejection fraction. Esc heart failure, 8(2), 1304-1313. https://doi.org/10.1002/ehf2.13204
    • Hazebroek, M. R., Henkens, M. T. H. M., Raafs, A. G., Verdonschot, J. A. J., Merken, J. J., Dennert, R. M., Eurlings, C., Hamid, M. A. A., Wolffs, P. F. G., Winkens, B., Brunner-La Rocca, H. P., Knackstedt, C., van Paassen, P., van Empel, V. P. M., & Heymans, S. R. B. (2021). Intravenous immunoglobulin therapy in adult patients with idiopathic chronic cardiomyopathy and cardiac parvovirus B19 persistence: a prospective, double-blind, randomized, placebo-controlled clinical trial. European journal of heart failure, 23(2), 302-309. https://doi.org/10.1002/ejhf.2082
  • 2020
    • Verdonschot, J. A. J., Merken, J. J., van Stipdonk, A. M. W., Pliger, P., Derks, K. W. J., Wang, P., Henkens, M. T. H. M., van Paassen, P., Hamid, M. A. A., van Empel, V. P. M., Knackstedt, C., Luermans, J. G. L. M., Crijns, H. J. G. M., Brunner-La Rocca, H.-P., Brunner, H. G., Poelzl, G., Vernooy, K., Heymans, S. R. B., & Hazebroek, M. R. (2020). Cardiac Inflammation Impedes Response to Cardiac Resynchronization Therapy in Patients With Idiopathic Dilated Cardiomyopathy. Circulation-Arrhythmia and Electrophysiology, 13(11), 1311-1320. Article 008727. https://doi.org/10.1161/circep.120.008727
    • Remmelzwaal, S., van Ballegooijen, A. J., Schoonmade, L. J., Dal Canto, E., Handoko, M. L., Henkens, M. T. H. M., van Empel, V., Heymans, S. R. B., & Beulens, J. W. J. (2020). Natriuretic peptides for the detection of diastolic dysfunction and heart failure with preserved ejection fraction-a systematic review and meta-analysis. BMC Medicine, 18(1), Article 290. https://doi.org/10.1186/s12916-020-01764-x
    • Breetveld, N. M., Alers, R.-J., Geerts, L., van Kuijk, S. M. J., van Dijk, A. P., van der Vlugt, M. J., Heidema, W. M., van Neer, J., van Empel, V. P. M., Brunner-La Rocca, H.-P., Scholten, R. R., Ghossein-Doha, C., & Spaanderman, M. E. A. (2020). Low Plasma Volume and Increased Pressure Load Relate to Concentric Left Ventricular Remodeling After Preeclampsia: A Longitudinal Study. Journal of the American Heart Association, 9(19), Article 015043. https://doi.org/10.1161/JAHA.119.015043
    • van Veldhuisen, D. J., van Woerden, G., Gorter, T. M., van Empel, V. P. M., Manintveld, O. C., Tieleman, R. G., Maass, A. H., Vernooy, K., Westenbrink, B. D., van Gelder, I. C., & Rienstra, M. (2020). Ventricular tachyarrhythmia detection by implantable loop recording in patients with heart failure and preserved ejection fraction: the VIP-HF study. European journal of heart failure, 22(10), 1923-1929. https://doi.org/10.1002/ejhf.1970
    • Henkens, M. T. H. M., Remmelzwaal, S., Robinson, E. L., van Ballegooijen, A. J., Aizpurua, A. B., Verdonschot, J. A. J., Raafs, A. G., Weerts, J., Hazebroek, M. R., Wijk, S. S., Handoko, M. L., den Ruijter, H. M., Lam, C. S. P., de Boer, R. A., Paulus, W. J., van Empel, V. P. M., Vos, R., Brunner-La Rocca, H.-P., Beulens, J. W. J., & Heymans, S. R. B. (2020). Risk of bias in studies investigating novel diagnostic biomarkers for heart failure with preserved ejection fraction. A systematic review. European journal of heart failure, 22(9), 1586-1597. https://doi.org/10.1002/ejhf.1944
Overview