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Social and economic background influences survival in intensive care: Research with societal impact

Social and economic background influences survival in intensive care: Research with societal impact

18 August 2026

A large-scale study by researchers from Maastricht UMC+ and Amsterdam UMC demonstrates that lower socioeconomic status (SES) of patients admitted to Dutch intensive care units contributes to worse survival.

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Fatma Karapinar appointed as Professor in Medication Safety

Fatma Karapinar appointed as Professor in Medication Safety

12 August 2026

As of 1 June 2026, Dr Fatma Karapinar has been appointed Professor of Medication Safety at Maastricht University.

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Carim Maastricht
Carim Maastricht

Michiel Henkens

Michiel Henkens studied Health Sciences and Medicine at Maastricht University, obtaining his bachelor’s degrees in 2014 and his master’s degree in Medicine with distinction in 2019. During his studies, he became actively involved in research at the Departments of Pathology and Cardiology at Maastricht University Medical Center (MUMC+).

After graduating, he started as a clinical PhD candidate at the Department of Cardiology at MUMC+. His doctoral research, described in his thesis “Improving diagnosis and risk stratification of cardiomyopathies across the ejection fraction spectrum“, focused on improving the diagnosis and risk stratification of cardiomyopathies and heart failure.

In July 2022, he started his residency training in Pathology at MUMC+, which he continued at University Medical Center Utrecht (UMCU) in November 2025. In 2025, he also started a postgraduate Master in Cardiovascular Pathology at the University of Padua. Combining his background in cardiology with his training in pathology, he has developed a particular interest in cardiovascular and autopsy pathology, with a focus on bridging diagnostic pathology and translational cardiovascular research.

Michiel’s research (within the group of Prof. S.R.B. Heymans) focuses on cardiovascular pathology and translational cardiovascular research, with a particular interest in bridging clinical cardiovascular diagnosis and prognostication with tissue-based pathological findings.

Since 2021, he has led the development of the Netherlands Heart Institute Heart Tissue Bank (NLHI-Hartenbank; www.hartenbank.nl), a national initiative that facilitates cardiovascular research by providing researchers with well-characterized human cardiac tissue and associated clinical data. The continued development of the NLHI-Hartenbank is supported by funding from the Dutch Heart Foundation.

Alongside his clinical training in pathology, Michiel continues his postdoctoral research and is involved in national and international cardiovascular and pathology networks. His research interests lie particularly at the intersection of cardiovascular pathology, post-mortem diagnostics, and clinical cardiovascular research, aiming to use human cardiac tissue and clinicopathological data to improve our understanding, diagnosis, and risk stratification of cardiovascular diseases.

Michiel foto

Department of Cardiology & Pathology

  • 2026
    • Zwetsloot, P.-P., Henkens, M. T. H. M., van Iperen, E. P. A., Minten, M., van der Schaaf-de Wolf, E., van Laake, L. W., te Riele, A. S. J. M., van der Harst, P., van Setten, J., van Empel, V. P. M., Brunner-La Rocca, H.-P., Verdonschot, D. J. A. J., Cox, M. G. P. J., Christiaans, I., Ajmone Marsan, N., van Spaendonck-Zwarts, K., Barge-Schaapveld, D. Q. C. M., Cramer, E., Hoedemakers, Y. M., ... DCR Investigators (2026). The Dutch cardiomyopathy registry (DCR); rationale and registry design. Netherlands Heart Journal, 34(9), 288-298. https://doi.org/10.1007/s12471-026-02063-5
    • Dinnessen, R., Antonissen, N., Peeters, D., Gietema, H. A., Henkens, M. T. H. M., Mohamed Hoesein, F. A. A., Scholten, E. T., Schaefer-Prokop, C., & Jacobs, C. (2026). Multicentre performance and consistency of two deep learning models for malignancy probability estimation of incidental pulmonary nodules. European Radiology. Advance online publication. https://doi.org/10.1007/s00330-026-12787-y
    • Sikking, M. A., Peisker, F., Maatz, H., Lopez-Anguita, N., Hazebroek, M. R., Henkens, M. T. H. M., Raafs, A. G., Heymans, A. B. M., Stroeks, S. L. V. M., Abdul Hamid, M. A., Li, X., Vicenzetto, C., Caforio, A. L. P., Brunner-La Rocca, H.-P., Knackstedt, C., van Paassen, P., van Empel, V. P. M., Hubner, N., Verdonschot, J. A. J., & Heymans, S. R. B. (2026). Improved outcome up to 10 years after intravenous immunoglobulin therapy in patients with dilated cardiomyopathy. European journal of heart failure. Advance online publication. https://doi.org/10.1093/ejhf/xuag134
    • Dieleman, S., Kooreman, L. F. S., Henkens, M. T. H. M., Hausen, A. Z., Smidt, M. L., & Grabsch, H. I. (2026). Histiocyte Quantity in Tumor-Negative Sentinel Lymph Nodes Predicts 10-Year Disease-Free Survival in Patients With Breast Cancer. Clinical Breast Cancer, 26(3), 247-256.e3. https://doi.org/10.1016/j.clbc.2025.11.015
    • Mourmans, S. G. J., Achten, A., Weerts, J., Scheepers, M., Barandiarán Aizpurua, A., Henkens, M., Uszko-Lencer, N., Brunner-La Rocca, H.-P., Knackstedt, C., & van Empel, V. P. M. (2026). The diagnostic yield of an elaborate workup for comorbidities in a real-life heart failure with preserved ejection fraction outpatient population. European Journal of Preventive Cardiology, 33(2), 276-285. https://doi.org/10.1093/eurjpc/zwaf429
  • 2025
    • Venner, M. F. G. H. M., Heymans, A. B. M., Beelen, N. J., Stroeks, S. L. V. M., Faassen, I. M. E., Sikking, M. A., Henkens, M. T. H. M., Van Der Crabben, S. N., Raafs, A. G., Heymans, S. R. B., & Verdonschot, J. A. J. (2025). Predictive value of ambulatory ECG monitoring for malignant arrhythmic events in genetic dilated cardiomyopathy. EP Europace, 27(11), Article euaf279. https://doi.org/10.1093/europace/euaf279
    • Stroeks, S. L. V. M., Merlo, M., Mora-Ayestaran, N., Jason, M., Tayal, U., Wang, P., Cannatà, A., Sikking, M. A., Dal Ferro, M., Peiro, B., Willemars, M., Hellebrekers, D. M. E. I., van Leeuwen, R. E. W., Setti, M., Gonzalez-Lopez, E., Krapels, I. P. C., Pio Loco Detto Gava, C., van den Wijngaard, A., Henkens, M. T. H. M., ... Verdonschot, J. A. J. (2025). Sex Differences in Prognosis of Patients With Genetic Dilated Cardiomyopathy. Circulation-Heart Failure, 18(11), e012592. Article 012592. https://doi.org/10.1161/CIRCHEARTFAILURE.124.012592
    • Sikking, M., Wiethoff, I., Henkens, M., Evers, S., Stroeks, S., Venner, M., Weerts, J., Brunner-la Rocca, H.-P., Knackstedt, C., van Empel, V., Michels, M., Heymans, S., Hiligsmann, M., & Verdonschot, J. (2025). High societal costs and reduced health-related quality of life in inflammatory and systemic immune disease-associated dilated cardiomyopathies. Quality of Life Research, 34(10), 2901-2910. https://doi.org/10.1007/s11136-025-04027-5
    • Weerts, J., Mourmans, S. G. J., Lopez-Martinez, H., Domingo, M., Aizpurua, A. B., Henkens, M. T. H. M., Achten, A., Lupon, J., Brunner-La Rocca, H.-P., Knackstedt, C., Bayes-Genis, A., & van Empel, V. P. M. (2025). Inter-atrial block as a predictor of adverse outcomes in patients with HFpEF. Esc heart failure, 12(3), 2287-2297. https://doi.org/10.1002/ehf2.15179
    • Stroeks, S. L. V. M., Henkens, M. T. H. M., Dominguez, F., Merlo, M., Hellebrekers, D. M. E. I., Gonzalez-Lopez, E., Dal Ferro, M., Ochoa, J. P., Venturelli, F., Claes, G. R. F., Venner, M. F. G. H. M., Krapels, I. P. C., Vanhoutte, E. K., van Paassen, P., van den Wijngaard, A., Sikking, M. A., van Leeuwen, R., Abdul Hamid, M., Li, X., ... Verdonschot, J. A. J. (2025). Genetic Landscape of Patients With Dilated Cardiomyopathy and a Systemic Immune-Mediated Disease. JACC: Heart Failure, 13(1), 133-145. https://doi.org/10.1016/j.jchf.2024.08.011
  • 2024
    • Sikking, M. A., Harding, D., Henkens, M. T. H. M., Stroeks, S. L. V. M., Venner, M. F. G. H. M., Nihant, B., van Leeuwen, R. E. W., Fanti, S., Li, X., van Paassen, P., Knackstedt, C., Brunner-la Rocca, H.-P., van Empel, V. P. M., Verdonschot, J. A. J., Marelli-Berg, F. M., & Heymans, S. R. B. (2024). Cytotoxic T-Cells Drive Outcome in Inflammatory Dilated Cardiomyopathy. Circulation Research, 135(12), 1193-1195. https://doi.org/10.1161/CIRCRESAHA.124.325183
    • Wiethoff, I., Sikking, M., Evers, S., Gabrio, A., Henkens, M., Michels, M., Verdonschot, J., Heymans, S., & Hiligsmann, M. (2024). Quality of life and societal costs in patients with dilated cardiomyopathy. European heart journal - Quality of care & clinical outcomes, 10(4), 334-344. Article qcad056. https://doi.org/10.1093/ehjqcco/qcad056
    • Sikking, M. A., Stroeks, S. L. V. M., Henkens, M. T. H. M., Raafs, A. G., Cossins, B., van Deuren, R. C., Steehouwer, M., Riksen, N. P., van den Wijngaard, A., Brunner, H. G., Hoischen, A., Verdonschot, J. A. J., & Heymans, S. R. B. (2024). Clonal Hematopoiesis has Prognostic Value in Dilated Cardiomyopathy independent of Age and Clone Size. JACC: Heart Failure, 12(5), 905-914. https://doi.org/10.1016/j.jchf.2023.06.037
    • HENKENS, MICHIEL. T. H. M., RAAFS, ANNE. G., VANLOON, T. I. M., VOS, JACQUELINE. L., VANDENWIJNGAARD, ARTHUR., BRUNNER, HAN. G., KRAPELS, INGRID. P. C., KNACKSTEDT, CHRISTIAN., GERRETSEN, SUZANNE., HAZEBROEK, MARK. R., VERNOOY, KEVIN., NIJVELDT, ROBIN., LUMENS, JOOST., & VERDONSCHOT, JOB. A. J. (2024). Left Atrial Function in Patients with Titin Cardiomyopathy. Journal of Cardiac Failure, 30(1), 51-60. https://doi.org/10.1016/j.cardfail.2023.05.013
  • 2023
    • Raafs, A. G., Adriaans, B. P., Henkens, M. T. H. M., Verdonschot, J. A. J., Abdul Hamid, M. A., Díez, J., Knackstedt, C., van Empel, V. P. M., Brunner-La Rocca, H. P., González, A., Wildberger, J. E., Heymans, S. R. B., & Hazebroek, M. R. (2023). Biomarkers of Collagen Metabolism Are Associated with Left Ventricular Function and Prognosis in Dilated Cardiomyopathy: A Multi-Modal Study. Journal of Clinical Medicine, 12(17), Article 5695. https://doi.org/10.3390/jcm12175695
    • Vos, J. L., Raafs, A. G., Henkens, M. T. H. M., Pedrizzetti, G., van Deursen, C. J., Rodwell, L., Heymans, S. R. B., & Nijveldt, R. (2023). CMR-derived left ventricular intraventricular pressure gradients identify different patterns associated with prognosis in dilated cardiomyopathy. European Heart Journal Cardiovascular Imaging, 24(9), 1231-1240. https://doi.org/10.1093/ehjci/jead083
    • Sikking, M. A., Stroeks, S. L. V. M., Waring, O. J., Henkens, M. T. H. M., Riksen, N. P., Hoischen, A., Heymans, S. R. B., & Verdonschot, J. A. J. (2023). Clonal Hematopoiesis of Indeterminate Potential From a Heart Failure Specialist’s Point of View. Journal of the American Heart Association, 12(15), Article e030603. https://doi.org/10.1161/JAHA.123.030603
    • Stroeks, S. L. V. M., Hellebrekers, D., Claes, G. R. F., Krapels, I. P. C., Henkens, M. H. T. M., Sikking, M., Vanhoutte, E. K., van den Enden, A. T. J. M. H., Brunner, H. G., van den Wijngaard, A., & Verdonschot, J. A. J. (2023). Diagnostic and prognostic relevance of using large gene panels in the genetic testing of patients with dilated cardiomyopathy. European Journal of Human Genetics, 31(7), 776-783. https://doi.org/10.1038/s41431-023-01384-y
    • Sikking, M. A., Stroeks, S. L. V. M., Henkens, M. T. H. M., Venner, M. F. G. H. M., Li, X., Heymans, S. R. B., Hazebroek, M. R., & Verdonschot, J. A. J. (2023). Cardiac Inflammation in Adult-Onset Genetic Dilated Cardiomyopathy. Journal of Clinical Medicine, 12(12), Article 3937. https://doi.org/10.3390/jcm12123937
    • Vermeer, M. C. S. C., Arevalo Gomez, K. F., Hoes, M. F., Tromp, J., Verdonschot, J. A. J., Henkens, M. T. H. M., Silljé, H. H. W., Bolling, M. C., & van der Meer, P. (2023). Clinical Outcome in KLHL24 Cardiomyopathy. Circulation: Genomic and Precision Medicine, 16(4), 401-403. https://doi.org/10.1161/CIRCGEN.122.003998
    • Verdonschot, J. A. J., Wang, P., Derks, K. W. J., Adriaens, M. E., Stroeks, S. L. V. M., Henkens, M. T. H. M., Raafs, A. G., Sikking, M., de Koning, B., van den Wijngaard, A., Krapels, I. P. C., Nabben, M., Brunner, H. G., & Heymans, S. R. B. (2023). Clustering of Cardiac Transcriptome Profiles Reveals Unique Subgroups of Dilated Cardiomyopathy Patients. JACC: Basic to Translational Science, 8(4), 406-418. https://doi.org/10.1016/j.jacbts.2022.10.010
    • Strand, M. E., Vanhaverbeke, M., Henkens, M. T. H. M., Sikking, M. A., Rypdal, K. B., Braathen, B., Almaas, V. M., Tonnessen, T., Christensen, G., Heymans, S., & Lunde, I. G. (2023). Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease. Biomedicines, 11(4), Article 1066. https://doi.org/10.3390/biomedicines11041066
    • Stroeks, S. L. V. M., Lunde, I. G. G., Hellebrekers, D. M. E. I., Claes, G. R. F., Wakimoto, H., Gorham, J., Krapels, I. P. C., Vanhoutte, E. K. K., van den Wijngaard, A., Henkens, M. T. H. M., Raafs, A. G. G., Sikking, M. A. A., Broers, J. L. V., Nabben, M., Jones, E. A. V., Heymans, S. R. B., Brunner, H. G. G., & Verdonschot, J. A. J. (2023). Prevalence and Clinical Consequences of Multiple Pathogenic Variants in Dilated Cardiomyopathy. Circulation: Genomic and Precision Medicine, 16(2), Article e003788. https://doi.org/10.1161/CIRCGEN.122.003788
    • Nuzzi, V., Raafs, A., Manca, P., Henkens, M. T. H. M., Gregorio, C., Boscutti, A., Verdonschot, J., Hazebroek, M., Knackstedt, C., Merlo, M., Stolfo, D., Sinagra, G., & Heymans, S. R. B. (2023). Left Atrial Reverse Remodeling in Dilated Cardiomyopathy. Journal of the American Society of Echocardiography, 36(2), 154-162. https://doi.org/10.1016/j.echo.2022.10.017
    • Henkens, M. T. H. M., van Ast, J. F., te Riele, A. S. J. M., Houweling, A. C., Amin, A. S., Nijveldt, R., Antoni, M. L., Li, X., Wehrens, S. M. T., von der Thusen, J. H., Damman, K., ter Horst, E. N., Manintveld, O. C., Abma-Schouten, R. Y., Niessen, H. W. M., Sillje, H. H. W., Jukema, J. W., & Doevendans, P. A. (2023). The Netherlands Heart Tissue Bank Strengthening the cardiovascular research infrastructure with an open access Cardiac Tissue Repository. Netherlands Heart Journal, 31(1), 16-20. https://doi.org/10.1007/s12471-022-01713-8
  • 2022
    • Raafs, A. G., Henkens, M. T. H. M., Vos, J. L., Nijveldt, R., & Verdonschot, J. A. J. (2022). REPLY: Further Insights Into the Prognostic Value of Left Atrial Strain in Dilated Cardiomyopathy?JACC-Cardiovascular Imaging, 15(12), 2156-2157. https://doi.org/10.1016/j.jcmg.2022.09.017
    • Sammani, A., van de Leur, R. R., Henkens, M. T. H. M., Meine, M., Loh, P., Hassink, R. J., Oberski, D. L., Heymans, S. R. B., Doevendans, P. A., Asselbergs, F. W., te Riele, A. S. J. M., & van Es, R. (2022). Life-threatening ventricular arrhythmia prediction in patients with dilated cardiomyopathy using explainable electrocardiogram-based deep neural networks. EP Europace, 24(10), 1645-1654. https://doi.org/10.1093/europace/euac054
    • Raafs, A. G., Adriaans, B. P., Henkens, M. T. H. M., Verdonschot, J. A. J., Ramaekers, M. J. F. G., Gommers, S., Hamid, M. A. A., Schalla, S., Knackstedt, C., van Empel, V. P. M., Hans-Peter, B., Wildberger, J. E., Bekkers, S. C. A. M., & Hazebroek, M. R. (2022). Myocardial Fibrosis Assessment Using T1 and ECV Mapping With Histologic Validation in Chronic Dilated Cardiomyopathy. JACC-Cardiovascular Imaging, 15(10), 1828-1830. https://doi.org/10.1016/j.jcmg.2022.05.002
    • Escobar-Lopez, L., Ochoa, J. P., Royuela, A., Verdonschot, J. A. J., Dal Ferro, M., Espinosa, M. A., Sabater-Molina, M., Gallego-Delgado, M., Larrañaga-Moreira, J. M., Garcia-Pinilla, J. M., Basurte-Elorz, M. T., Rodríguez-Palomares, J. F., Climent, V., Bermudez-Jimenez, F. J., Mogollón-Jiménez, M. V., Lopez, J., Peña-Peña, M. L., Garcia-Alvarez, A., López-Abel, B., ... Garcia-Pavia, P. (2022). Clinical Risk Score to Predict Pathogenic Genotypes in Patients With Dilated Cardiomyopathy. Journal of the American College of Cardiology, 80(12), 1115-1126. https://doi.org/10.1016/j.jacc.2022.06.040
    • Henkens, M. T. H. M., Stroeks, S. L. V. M., Raafs, A. G., Sikking, M. A., Tromp, J., Ouwerkerk, W., Hazebroek, M. R., Krapels, I. P. C., Knackstedt, C., van den Wijngaard, A., Brunner, H. G., Heymans, S. R. B., & Verdonschot, J. A. J. (2022). Dynamic Ejection Fraction Trajectory in Patients With Dilated Cardiomyopathy With a Truncating Titin Variant. Circulation-Heart Failure, 15(8), Article e009352. https://doi.org/10.1161/CIRCHEARTFAILURE.121.009352
    • Henkens, M. T. H. M., Martinez, H. L., Weerts, J., Sammani, A., Raafs, A. G., Verdonschot, J. A. J., van de Leur, R. R., Sikking, M. A., Stroeks, S., van Empel, V. P. M., Brunner-La Rocca, H. P., van Stipdonk, A. M. W., Farmakis, D., Hazebroek, M. R., Vernooy, K., Bayes-de-Luna, A., Asselbergs, F. W., Bayes-Genis, A., & Heymans, S. R. B. (2022). Interatrial Block Predicts Life-Threatening Arrhythmias in Dilated Cardiomyopathy. Journal of the American Heart Association, 11(14), Article e025473. https://doi.org/10.1161/JAHA.121.025473
    • Raafs, A. G., Ghossein, M. A., Brandt, Y., Henkens, M. T. H. M., Kooi, M. E., Vernooy, K., Spaanderman, M. E. A., Gerretsen, S., van Santen, S., Driessen, R. G. H., Knackstedt, C., van der Horst, I. C. C., van Bussel, B. C. T., Heymans, S. R. B., Ghossein-Doha, C., & MaastrICCht Collaborators (2022). Cardiovascular outcome 6 months after severe coronavirus disease 2019 infection. Journal of Hypertension, 40(7), 1278-1287. https://doi.org/10.1097/hjh.0000000000003110
    • van de Leur, R. R., Bleijendaal, H., Taha, K., Mast, T., Gho, J. M. I. H., Linschoten, M., van Rees, B., Henkens, M. T. H. M., Heymans, S., Sturkenboom, N., Tio, R. A., Offerhaus, J. A., Bor, W. L., Maarse, M., Haerkens-Arends, H. E., Kolk, M. Z. H., van der Lingen, A. C. J., Selder, J. J., Wierda, E. E., ... CAPACITY-COVID collaborative consortium (2022). Electrocardiogram-based mortality prediction in patients with COVID-19 using machine learning. Netherlands Heart Journal, 30(6), 312-318. https://doi.org/10.1007/s12471-022-01670-2
    • Raafs, A. G., Vos, J. L., Henkens, M. T. H. M., Slurink, B. O., Verdonschot, J. A. J., Bossers, D., Roes, K., Gerretsen, S., Knackstedt, C., Hazebroek, M. R., Nijveldt, R., & Heymans, S. R. B. (2022). Left Atrial Strain Has Superior Prognostic Value to Ventricular Function and Delayed-Enhancement in Dilated Cardiomyopathy. JACC-Cardiovascular Imaging, 15(6), 1015-1026. https://doi.org/10.1016/j.jcmg.2022.01.016
    • Henkens, M. T. H. M., van Ommen, A. M., Remmelzwaal, S., Valstar, G. B., Wang, P., Verdonschot, J. A. J., Hazebroek, M. R., Hofstra, L., Empel, V. P. M., Beulens, J. W. J., Ruijter, H. M., & Heymans, S. R. B. (2022). The HFA-PEFF score identifies 'early-HFpEF' phenogroups associated with distinct biomarker profiles. Esc heart failure, 9(3), 2032-2036. https://doi.org/10.1002/ehf2.13861
    • Verdonschot, J. A. J., Ferreira, J. P., Pizard, A., Pellicori, P., Brunner La Rocca, H.-P., Clark, A. L., Cosmi, F., Cuthbert, J., Girerd, N., Waring, O. J., Henkens, M. H. T. M., Mariottoni, B., Petutschnigg, J., Rossignol, P., Hazebroek, M. R., Cleland, J. G. F., Zannad, F., Heymans, S. R. B., & HOMAGE “Heart Omics in AGEing” consortium (2022). The Effect of Spironolactone in Patients With Obesity at Risk for Heart Failure: Proteomic Insights from the HOMAGE Trial. Journal of Cardiac Failure, 28(5), 778-786. https://doi.org/10.1016/j.cardfail.2021.12.005
    • Henkens, M. T. H. M., Weerts, J., Verdonschot, J. A. J., Raafs, A. G., Stroeks, S., Sikking, M. A., Amin, H., Mourmans, S. G. J., Geraeds, C. B. G., Sanders-van Wijk, S., Aizpurua, A. B., Uszko-Lencer, N. H. M. K., Krapels, I. P. C., Wolffs, P. F. G., Brunner, H. G., Leeuwen, R. E. W., Verhesen, W., Schalla, S. M., van Stipdonk, A. W. M., ... Heymans, S. R. B. (2022). Improving diagnosis and risk stratification across the ejection fraction spectrum: the Maastricht Cardiomyopathy registry. Esc heart failure, 9(2), 1463-1470. https://doi.org/10.1002/ehf2.13833
    • Raafs, A. G., Boscutti, A., Henkens, M. T. H. M., van den Broek, W. W. A., Verdonschot, J. A. J., Weerts, J., Stolfo, D., Nuzzi, V., Manca, P., Hazebroek, M. R., Knackstedt, C., Merlo, M., Heymans, S. R. B., & Sinagra, G. (2022). Global Longitudinal Strain is Incremental to Left Ventricular Ejection Fraction for the Prediction of Outcome in Optimally Treated Dilated Cardiomyopathy Patients. Journal of the American Heart Association, 11(6), Article e024505. https://doi.org/10.1161/JAHA.121.024505
    • Linschoten, M., Uijl, A., Schut, A., Jakob, C. E. M., Romao, L. R., Bell, R. M., McFarlane, E., Stecher, M., Zondag, A. G. M., van Iperen, E. P. A., Hermans-van Ast, J. F., Lea, N. C., Schaap, J., Jewbali, L. S., Smits, P. C., Patel, R. S., Aujayeb, A., van Smeden, M., Siebelink, H. J., ... Raafs, A. (2022). Clinical presentation, disease course, and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease: a cohort study across 18 countries. European Heart Journal, 43(11), 1104-1120. https://doi.org/10.1093/eurheartj/ehab656
    • Henkens, M. T. H. M., Raafs, A. G., Verdonschot, J. A. J., Linschoten, M., van Smeden, M., Wang, P., van der Hooft, B. H. M., Tieleman, R., Janssen, M. L. F., Ter Bekke, R. M. A., Hazebroek, M. R., van der Horst, I. C. C., Asselbergs, F. W., Magdelijns, F. J. H., Heymans, S. R. B., & CAPACITY-COVID collaborative consortium (2022). Age is the main determinant of COVID-19 related in-hospital mortality with minimal impact of pre-existing comorbidities, a retrospective cohort study. BMC Geriatrics, 22(1), Article 184. https://doi.org/10.1186/s12877-021-02673-1
    • Weerts, J., Barandiarán Aizpurua, A., Henkens, M. T. H. M., Lyon, A., van Mourik, M. J. W., van Gemert, M. R. A. A., Raafs, A., Sanders-van Wijk, S., Bayés-Genís, A., Heymans, S. R. B., Crijns, H. J. G. M., Brunner-La Rocca, H.-P., Lumens, J., van Empel, V. P. M., & Knackstedt, C. (2022). The prognostic impact of mechanical atrial dysfunction and atrial fibrillation in heart failure with preserved ejection fraction. European Heart Journal Cardiovascular Imaging, 23(1), 74-84. https://doi.org/10.1093/ehjci/jeab222
  • 2021
    • Stroeks, S. L. V. M., Hellebrekers, D. M. E. I., Claes, G. R. F., Tayal, U., Krapels, I. P. C., Vanhoutte, E. K., van den Wijngaard, A., Henkens, M. T. H. M., Ware, J. S., Heymans, S. R. B., Brunner, H. G., & Verdonschot, J. A. J. (2021). Clinical impact of re-evaluating genes and variants implicated in dilated cardiomyopathy. Genetics in Medicine, 23(11), 2186-2193. https://doi.org/10.1038/s41436-021-01255-1
    • Verdonschot, J. A. J., Henkens, M. T. H. M., Wang, P., Schummers, G., Raafs, A. G., Krapels, I. P. C., van Empel, V., Heymans, S. R. B., Brunner-La Rocca, H.-P., & Knackstedt, C. (2021). A global longitudinal strain cut-off value to predict adverse outcomes in individuals with a normal ejection fraction. Esc heart failure, 8(5), 4343-4345. https://doi.org/10.1002/ehf2.13465
    • Raafs, A., Verdonschot, J., Ferreira, J. P., Wang, P., Collier, T., Henkens, M., Bjorkman, J., Boccanelli, A., Clark, A. L., Delles, C., Diez, J., Gonzalez, A., Girerd, N., Jukema, J. W., Pinet, F., Rossignol, P., Thum, T., Vodovar, N., de Boer, R. A., ... Heymans, S. (2021). Identification of sex-specific biomarkers predicting new-onset heart failure. Esc heart failure, 8(5), 3512-3520. https://doi.org/10.1002/ehf2.13476
    • Raafs, A. G., Verdonschot, J. A. J., Henkens, M. T. H. M., Adriaans, B. P., Wang, P., Derks, K., Abdul Hamid, M. A., Knackstedt, C., van Empel, V. P. M., Diez, J., Brunner-La Rocca, H.-P., Brunner, H. G., Gonzalez, A., Bekkers, S. C. A. M., Heymans, S. R. B., & Hazebroek, M. R. (2021). The combination of carboxy-terminal propeptide of procollagen type I blood levels and late gadolinium enhancement at cardiac magnetic resonance provides additional prognostic information in idiopathic dilated cardiomyopathy - A multilevel assessment of myocardial fibrosis in dilated cardiomyopathy. European journal of heart failure, 23(6), 933-944. https://doi.org/10.1002/ejhf.2201
    • Sanders-van Wijk, S., Barandiaran Aizpurua, A., Brunner-La Rocca, H.-P., Henkens, M. T. H. M., Weerts, J., Knackstedt, C., Uszko-Lencer, N., Heymans, S., & van Empel, V. (2021). The HFA-PEFF and H2FPEF scores largely disagree in classifying patients with suspected heart failure with preserved ejection fraction. European journal of heart failure, 23(5), 838-840. https://doi.org/10.1002/ejhf.2019
    • Barandiarán Aizpurua, A., Sanders-van Wijk, S., Brunner-La Rocca, H. P., Henkens, M. T. H. M., Weerts, J., Spanjers, M. H. A., Knackstedt, C., & van Empel, V. P. M. (2021). Iron deficiency impacts prognosis but less exercise capacity in heart failure with preserved ejection fraction. Esc heart failure, 8(2), 1304-1313. https://doi.org/10.1002/ehf2.13204
    • Hazebroek, M. R., Henkens, M. T. H. M., Raafs, A. G., Verdonschot, J. A. J., Merken, J. J., Dennert, R. M., Eurlings, C., Hamid, M. A. A., Wolffs, P. F. G., Winkens, B., Brunner-La Rocca, H. P., Knackstedt, C., van Paassen, P., van Empel, V. P. M., & Heymans, S. R. B. (2021). Intravenous immunoglobulin therapy in adult patients with idiopathic chronic cardiomyopathy and cardiac parvovirus B19 persistence: a prospective, double-blind, randomized, placebo-controlled clinical trial. European journal of heart failure, 23(2), 302-309. https://doi.org/10.1002/ejhf.2082
    • Meier, S., Henkens, M., Heymans, S., & Robinson, E. L. (2021). Unlocking the Value of White Blood Cells for Heart Failure Diagnosis. Journal of Cardiovascular Translational Research, 14(1), 53-62. https://doi.org/10.1007/s12265-020-10007-6
Overview