Hans-Peter Brunner-La Rocca

Professor

Prof. Hans-Peter Brunner-La Rocca has graduated in medicine at the University of Zurich, Switzerland. He was trained in Internal Medicine and Cardiology in Switzerland. After doing a post-doc in Melbourne, Australia, for two years, he had been working as cardiologist and heart failure specialist in Zurich. In 2002, he moved to Basel, where he was responsible for the heart failure and heart transplant services. He has obtained his lecture qualification both in Zurich and in Basel and was announced as Professor in Basel Switzerland in 2008. Since 2009, he has been working at Maastricht UMC+ as Professor of Clinical Heart Failure. He is head of the heart failure clinic and head of the division of structural heart diseases.

He has been involved in numerous research projects since many years. In particular, he has a special interest in personalised medicine in heart failure using biomarkers and has successfully led international studies related to this topic. In addition, eHealth is an important focus of research. He has published >250 research articles.

He has been working as member of different working groups of the Heart Failure Association of the European Society of Cardiology and is board member of working group on heart failure in the Netherlands.

On the one hand, he is continuing his research on biomarker in heart failure for therapy guidance. He is collaborating internationally on this topic and is participating in several large international projects in this regard. On the other hand, he is leading an international consortium, aiming to develop a personalized eHealth application to enable patients with heart failure to perform self-care, i.e. including self-prescription of medication. Recently, the consortium received 4.4 M€ to support this project from INTERREG-NWE (budget Maastricht UMC+ > 2.0 M€).

He is additionally involved in national research projects (e.g. heart-brain connection, supported by CVON) and is the local PI of several large industry sponsored RCTs. In one of them, he is the national coordinator for the Netherlands.

Department of Cardiology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 3.B2.031
T: +31(0)43 387 70 97

  • 2023
    • Michelly Gonçalves Brandão, S., Brunner-La Rocca, H. P., Pedroso De Lima, A. C., & Alcides Bocchi, E. (2023). A review of cost-effectiveness analysis: From theory to clinical practice. Medicine, 102(42), Article e35614. https://doi.org/10.1097/MD.0000000000035614
    • Raafs, A. G., Adriaans, B. P., Henkens, M. T. H. M., Verdonschot, J. A. J., Abdul Hamid, M. A., Díez, J., Knackstedt, C., van Empel, V. P. M., Brunner-La Rocca, H. P., González, A., Wildberger, J. E., Heymans, S. R. B., & Hazebroek, M. R. (2023). Biomarkers of Collagen Metabolism Are Associated with Left Ventricular Function and Prognosis in Dilated Cardiomyopathy: A Multi-Modal Study. Journal of Clinical Medicine, 12(17), Article 5695. https://doi.org/10.3390/jcm12175695
    • Meijs, C., Brugts, J. J., Lund, L. H., Linssen, G. C. M., Brunner-La Rocca, H.-P., Dahlstrom, U., Vaartjes, I., Koudstaal, S., Asselbergs, F. W., Savarese, G., & Uijl, A. (2023). Identifying distinct clinical clusters in heart failure with mildly reduced ejection fraction. International Journal of Cardiology, 386(1), 83-90. https://doi.org/10.1016/j.ijcard.2023.05.024
    • Malgie, J., Clephas, P. R. D., Brunner-La Rocca, H.-P., de Boer, R. A., & Brugts, J. J. (2023). Guideline-directed medical therapy for HFrEF: sequencing strategies and barriers for life-saving drug therapy. Heart Failure Reviews, 28(5), 1221-1234. https://doi.org/10.1007/s10741-023-10325-2
    • Habibi, Z., Abma-Kramer, J., & Brunner-La Rocca, H.-P. (2023). A case report of high-output heart failure due to arteriovenous shunt without bowel: how to address?European Heart Journal - Case Reports, 7(8), Article ytad360. https://doi.org/10.1093/ehjcr/ytad360
    • Kobayashi, M., Huttin, O., Ferreira, J. P., Duarte, K., Gonzalez, A., Heymans, S., Verdonschot, J. A. J., Brunner-La Rocca, H.-P., Pellicori, P. L., Clark, A., Petutschnigg, J., Edelmann, F. G., Cleland, J., Rossignol, P., Zannad, F., Girerd, N., & HOMAGE Trial Committees and Investigators (2023). A machine learning-derived echocardiographic algorithm identifies people at risk of heart failure with distinct cardiac structure, function, and response to spironolactone: findings from the HOMAGE trial. European journal of heart failure, 25(8), 1284-1289. https://doi.org/10.1002/ejhf.2859
    • van Mourik, M. J. W., Linz, D., Verwijs, H. J. A., Bekkers, S. C. A. M., Weerts, J., Schotten, U., Rocca, H. B.-L., Lumens, J., Crijns, H. J. G. M., Weijs, B., & Knackstedt, C. (2023). Evaluating subclinical left ventricular and left atrial dysfunction in idiopathic atrial fibrillation: A speckle-tracking based strain-analysis. International Journal of Cardiology, 383(1), 159-165. https://doi.org/10.1016/j.ijcard.2023.04.024
    • Aga, Y. S., Radhoe, S. P., Aydin, D., Linssen, G. C. M., Rademaker, P. C., Geerlings, P. R., van Gent, M. W. F., Aksoy, I., Oosterom, L., Brunner-La Rocca, H. P. B. L., van Dalen, B. M., & Brugts, J. J. (2023). Heart failure treatment in patients with and without obesity with an ejection fraction below 50%. European Journal of Clinical Investigation, 53(7), Article e13976. https://doi.org/10.1111/eci.13976
    • Brugts, J. J., Radhoe, S. P., Clephas, P. R. D., Aydin, D., van Gent, M. W. F., Szymanski, M. K., Rienstra, M., van den Heuvel, M. H., da Fonseca, C. A., Linssen, G. C. M., Borleffs, C. J. W., Boersma, E., Asselbergs, F. W., Mosterd, A., Brunner-La Rocca, H. P., de Boer, R. A., Emans, M. E., Beeres, S. L. M. A., Heerebeek, L., ... MONITOR-HF investigators (2023). Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial. Lancet, 401(10394), 2113-2123. https://doi.org/10.1016/S0140-6736(23)00923-6
    • ter Bekke, R. M. A., de Schouwer, K., Conti, S., Claes, G. R. F., Vanoevelen, J., Gommers, S., Helderman-van den Enden, A. T. J. M., & Brunner-LaRocca, H.-P. (2023). Juvenile-onset multifocal atrial arrhythmias, atrial standstill and compound heterozygosity of genetic variants in TAF1A: sentinel event for evolving dilated cardiomyopathy-a case report. European Heart Journal - Case Reports, 7(6), Article ytad255. https://doi.org/10.1093/ehjcr/ytad255
    • Steiner, B., Neumann, A., Pelz, Y., Ski, C. F., Hill, L., Thompson, D. R., Fitzsimons, D., Dixon, L. J., Brandts, J., Verket, M., Schuett, K., Eurlings, C. G. M. J., Boyne, J. J. J., Gingele, A. J., De Maesschalck, L., Murphy, M., da Luz, E. F., Barrett, M., Windle, K., ... PASSION-HF consortium (2023). Challenges in heart failure care in four European countries: a comparative study. European Journal of Public Health, 33(3), 448-454. https://doi.org/10.1093/eurpub/ckad059
    • Knackstedt, C., Schummers, G., Schroder, J., Marx, N., Lumens, J., Sanders-van Wijk, S., Ramaekers, B., Becker, M., van Empel, V., Brunner-La Rocca, H. P., & PsychEcho study group (2023). A graphical analysis of aspects contributing to the spreading of measurements of left ventricular function. International Journal of Cardiovascular Imaging, 39(5), 915-927. https://doi.org/10.1007/s10554-023-02796-z
    • Starmans, N. L., Wolters, F. J., Leeuwis, A. E., Bron, E. E., La Rocca, H. P. B., Staals, J., Biessels, G. J., & Kappelle, L. J. (2023). Twenty-four hour blood pressure variability and the prevalence and the progression of cerebral white matter hyperintensities. Journal of Cerebral Blood Flow and Metabolism, 43(5), 801-811. https://doi.org/10.1177/0271678X221149937
    • Clephas, P. R. D., Radhoe, S. P., Linssen, G. C. M., Langerveld, J., Plomp, J., Smits, J. P. P., Nagelsmit, M. J., Rocca, H. P. B. L., & Brugts, J. J. (2023). Serum potassium level and mineralocorticoid receptor antagonist dose in a large cohort of chronic heart failure patients. Esc heart failure, 10(2), 1481-1487. https://doi.org/10.1002/ehf2.14285
    • Radhoe, S. P., Clephas, P. R. D., Linssen, G. C. M., Oortman, R. M., Smeele, F. J., Van Drimmelen, A. A., Schaafsma, H. J., Westendorp, P. H., Rocca, H. P. B. L., & Brugts, J. J. (2023). Phenotypic patient profiling for improved implementation of guideline-directed medical therapy: An exploratory analysis in a large real-world chronic heart failure cohort. Frontiers in Pharmacology, 14(1), Article 1081579. https://doi.org/10.3389/fphar.2023.1081579
    • Rohr, M., Brandenburg, V., & Rocca, H. P. B. (2023). How to diagnose iron deficiency in chronic disease: A review of current methods and potential marker for the outcome. European Journal of Medical Research, 28(1), Article 15. https://doi.org/10.1186/s40001-022-00922-6
    • Scherrenberg, M., Leenen, J. P. L., van der Velde, A. E., Boyne, J., Bruins, W., Vranken, J., Brunner-La Rocca, H. P., De Kluiver, E. P., & Dendale, P. (2023). Bringing the hospital to home: Patient-reported outcome measures of a digital health-supported home hospitalisation platform to support hospital care at home for heart failure patients. Digital health, 9(1), 1-10. Article 20552076231152178. https://doi.org/10.1177/20552076231152178
    • Gürgöze, M. T., van Vark, L. C., Baart, S. J., Kardys, I., Akkerhuis, K. M., Manintveld, O. C., Postmus, D., Hillege, H. L., Lesman-Leegte, I., Asselbergs, F. W., Brunner-la-Rocca, H.-P., van den Bos, E. J., Orsel, J. G., de Ridder, S. P. J., Pinto, Y. M., & Boersma, E. (2023). Multimarker Analysis of Serially Measured GDF-15, NT-proBNP, ST2, GAL-3, cTnI, Creatinine, and Prognosis in Acute Heart Failure. Circulation-Heart Failure, 16(1), Article e009526. https://doi.org/10.1161/CIRCHEARTFAILURE.122.009526
    • Timmermans, E. J., Leeuwis, A. E., Bots, M. L., van Alphen, J. L., Biessels, G. J., Brunner-La Rocca, H.-P., Kappelle, L. J., van Rossum, A. C., van Osch, M. J. P., Vaartjes, I., & Heart-Brain Connection Consortium (2023). Neighbourhood walkability in relation to cognitive functioning in patients with disorders along the heart-brain axis. Health & Place, 79(1), Article 102956. https://doi.org/10.1016/j.healthplace.2022.102956
    • Baldewijns, K., Boyne, J., Rohde, C., de Maesschalck, L., Devillé, A., Brandenburg, V., De Bleser, L., Derickx, M., Bektas, S., & Brunner-La Rocca, H.-P. (2023). What kind of patient education and self-care support do patients with heart failure receive, and by whom? Implementation of the ESC guidelines for heart failure in three European regions. Heart & Lung, 57(1), 25-30. https://doi.org/10.1016/j.hrtlng.2022.07.013
  • 2022
    • Anker, S. D., Butler, J., Usman, M. S., Filippatos, G., Ferreira, J. P., Bocchi, E., Böhm, M., Rocca, H. P. B.-L., Choi, D.-J., Chopra, V., Chuquiure, E., Giannetti, N., Gomez-Mesa, J. E., Janssens, S., Januzzi, J. L., González-Juanatey, J. R., Merkely, B., Nicholls, S. J., Perrone, S. V., ... Zannad, F. (2022). Efficacy of empagliflozin in heart failure with preserved versus mid-range ejection fraction: a pre-specified analysis of EMPEROR-Preserved. Nature Medicine, 28(12), 2512–2520. https://doi.org/10.1038/s41591-022-02041-5
    • Kuipers, S., Greving, J. P., Brunner-La Rocca, H.-P., Gottesman, R. F., van Oostenbrugge, R. J., Williams, N. L., Jan Biessels, G., Jaap Kappelle, L., & Heart-Brain Connection Consortium (2022). Risk evaluation of cognitive impairment in patients with heart failure: A call for action. IJC Heart and Vasculature, 43, Article 101133. https://doi.org/10.1016/j.ijcha.2022.101133
    • Gingele, A. J., Boyne, J., Knackstedt, C., & Brunner-La Rocca, H. P. (2022). The MIS-HF in clinical practice. Netherlands Heart Journal, 30(12), 582-583. https://doi.org/10.1007/s12471-022-01731-6
    • Lim, Y. M. F., Molnar, M., Vaartjes, I., Savarese, G., Eijkemans, M. J. C., Uijl, A., Vradi, E., Suzart-Woischnik, K., Brugts, J. J., Brunner-La Rocca, H.-P., Blanc-Guillemaud, V., Couvelard, F., Baudier, C., Dyszynski, T., Waechter, S., Lund, L. H., Hoes, A. W., Tyl, B., Asselbergs, F. W., ... Koudstaal, S. (2022). Generalizability of randomized controlled trials in heart failure with reduced ejection fraction. European heart journal - Quality of care & clinical outcomes, 8(7), 761–769. https://doi.org/10.1093/ehjqcco/qcab070
    • Raafs, A. G., Adriaans, B. P., Henkens, M. T. H. M., Verdonschot, J. A. J., Ramaekers, M. J. F. G., Gommers, S., Hamid, M. A. A., Schalla, S., Knackstedt, C., van Empel, V. P. M., Hans-Peter, B., Wildberger, J. E., Bekkers, S. C. A. M., & Hazebroek, M. R. (2022). Myocardial Fibrosis Assessment Using T1 and ECV Mapping With Histologic Validation in Chronic Dilated Cardiomyopathy. JACC-Cardiovascular Imaging, 15(10), 1828-1830. https://doi.org/10.1016/j.jcmg.2022.05.002
    • Herrmann, J. J., Beckers-Wesche, F., Baltussen, L. E. H. J. M., Verdijk, M. H. I., Bellersen, L., Brunner-la Rocca, H.-P., Jaarsma, T., Pisters, R., Sanders-van Wijk, S., Rodwell, L., Van Royen, N., Gommans, D. H. F., & Van Kimmenade, R. R. J. (2022). Fluid REStriction in Heart Failure vs Liberal Fluid UPtake: Rationale and Design of the Randomized FRESH-UP Study. Journal of Cardiac Failure, 28(10), 1522-1530. https://doi.org/10.1016/j.cardfail.2022.05.015
    • Eurlings, C. G. M. J., Bektas, S., Sanders-van Wijk, S., Tsirkin, A., Vasilchenko, V., Meex, S. J. R., Failer, M., Oehri, C., Ruff, P., Zellweger, M. J., & Brunner-La Rocca, H.-P. (2022). Use of artificial intelligence to assess the risk of coronary artery disease without additional (non-invasive) testing: validation in a low-risk to intermediate-risk outpatient clinic cohort. BMJ Open, 12(9), Article e055170. https://doi.org/10.1136/bmjopen-2021-055170
    • Gingele, A. J., Brandts, L., Brunner-La Rocca, H. P., Cleuren, G., Knackstedt, C., & Boyne, J. J. J. (2022). Introduction of a new scoring tool to identify clinically stable heart failure patients. Netherlands Heart Journal, 30(9), 402-410. https://doi.org/10.1007/s12471-021-01654-8
    • van Stipdonk, A. M. W., Schretlen, S., Dohmen, W., Knackstedt, C., Beckers-Wesche, F., Debie, L., Brunner-La Rocca, H.-P., & Vernooy, K. (2022). Better outcome at lower costs after implementing a CRT-care pathway: comprehensive evaluation of real-world data. Esc heart failure, 9(4), 2518-2527. https://doi.org/10.1002/ehf2.13958
    • Vergaro, G., Gentile, F., Aimo, A., Januzzi, J. L., Richards, A. M., Lam, C. S. P., de Boer, R. A., Meems, L. M. G., Latini, R., Staszewsky, L., Anand, I. S., Cohn, J. N., Ueland, T., Gullestad, L., Aukrust, P., Brunner-La Rocca, H.-P., Bayes-Genis, A., Lupón, J., Yoshihisa, A., ... Emdin, M. (2022). Circulating levels and prognostic cut-offs of sST2, hs-cTnT, and NT-proBNP in women vs. men with chronic heart failure. Esc heart failure, 9(4), 2084-2095. https://doi.org/10.1002/ehf2.13883
    • Henkens, M. T. H. M., Martinez, H. L., Weerts, J., Sammani, A., Raafs, A. G., Verdonschot, J. A. J., van de Leur, R. R., Sikking, M. A., Stroeks, S., van Empel, V. P. M., Brunner-La Rocca, H. P., van Stipdonk, A. M. W., Farmakis, D., Hazebroek, M. R., Vernooy, K., Bayes-de-Luna, A., Asselbergs, F. W., Bayes-Genis, A., & Heymans, S. R. B. (2022). Interatrial Block Predicts Life-Threatening Arrhythmias in Dilated Cardiomyopathy. Journal of the American Heart Association, 11(14), Article e025473. https://doi.org/10.1161/JAHA.121.025473
    • Veugen, M. G. J., Onete, V. G., Henry, R. M. A., Brunner-La Rocca, H.-P., Koster, A., Dagnelie, P. C., Schaper, N. C., Sep, S. J. S., van der Kallen, C. J. H., van Boxtel, M. P. J., Reesink, K. D., Schouten, J. S., Savelberg, H. H. C. M., Köhler, S., Verhey, F. R., van den Bergh, J. P. W., Schram, M. T., & Stehouwer, C. D. A. (2022). Health burden in type 2 diabetes and prediabetes in The Maastricht Study. Scientific Reports, 12(1), 1-11. Article 7337. https://doi.org/10.1038/s41598-022-11136-5
    • Verdonschot, J. A. J., Ferreira, J. P., Pizard, A., Pellicori, P., Brunner La Rocca, H.-P., Clark, A. L., Cosmi, F., Cuthbert, J., Girerd, N., Waring, O. J., Henkens, M. H. T. M., Mariottoni, B., Petutschnigg, J., Rossignol, P., Hazebroek, M. R., Cleland, J. G. F., Zannad, F., Heymans, S. R. B., & HOMAGE “Heart Omics in AGEing” consortium (2022). The Effect of Spironolactone in Patients With Obesity at Risk for Heart Failure: Proteomic Insights from the HOMAGE Trial. Journal of Cardiac Failure, 28(5), 778-786. https://doi.org/10.1016/j.cardfail.2021.12.005
    • Henkens, M. T. H. M., Weerts, J., Verdonschot, J. A. J., Raafs, A. G., Stroeks, S., Sikking, M. A., Amin, H., Mourmans, S. G. J., Geraeds, C. B. G., Sanders-van Wijk, S., Aizpurua, A. B., Uszko-Lencer, N. H. M. K., Krapels, I. P. C., Wolffs, P. F. G., Brunner, H. G., Leeuwen, R. E. W., Verhesen, W., Schalla, S. M., van Stipdonk, A. W. M., ... Heymans, S. R. B. (2022). Improving diagnosis and risk stratification across the ejection fraction spectrum: the Maastricht Cardiomyopathy registry. Esc heart failure, 9(2), 1463-1470. https://doi.org/10.1002/ehf2.13833
    • Ferreira, J. P., Collier, T., Clark, A. L., Mamas, M. A., Rocca, H.-P. B.-L., Heymans, S., González, A., Ahmed, F. Z., Petutschnigg, J., Mujaj, B., Cuthbert, J., Rouet, P., Pellicori, P., Mariottoni, B., Cosmi, F., Edelmann, F., Thijs, L., Staessen, J. A., Hazebroek, M., ... Zannad, F. (2022). Spironolactone effect on the blood pressure of patients at risk of developing heart failure: an analysis from the HOMAGE trial. European Heart Journal-Cardiovascular Pharmacotherapy, 8(2), 149-156. https://doi.org/10.1093/ehjcvp/pvab031
    • van Dalen, D. H., Kragten, J. A., Emans, M. E., Van Ofwegen-Hanekamp, C. E. E., Klaarwater, C. C. R., Spanjers, M. H. A., Hendrick, R., van Deursen, C. T. B. M., & Brunner-La Rocca, H. P. (2022). Acute heart failure and iron deficiency: a prospective, multicentre, observational study. Esc heart failure, 9(1), 398-407. https://doi.org/10.1002/ehf2.13737
    • Uszko-Lencer, N. H. M. K., Janssen, D. J. A., Gaffron, S., Vanfleteren, L. E. G. W., Janssen, E., Werter, C., Franssen, F. M. E., Wouters, E. F. M., Rechberger, S., Brunner La Rocca, H.-P., & Spruit, M. A. (2022). Clustering based on comorbidities in patients with chronic heart failure: an illustration of clinical diversity. Esc heart failure, 9(1), 614-626. https://doi.org/10.1002/ehf2.13704
    • Radhoe, S. P., Veenis, J. F., Linssen, G. C. M., van der Lee, C., Eurlings, L. W. M., Kragten, H., Al-Windy, N. Y. Y., van der Spank, A., Koudstaal, S., Brunner-La Rocca, H. P., & Brugts, J. J. (2022). Diabetes and treatment of chronic heart failure in a large real-world heart failure population. Esc heart failure, 9(1), 353-362. https://doi.org/10.1002/ehf2.13743
    • de Boer, A. R., Vaartjes, I., Gohar, A., Valk, M. J. M., Brugts, J. J., Boonman-de Winter, L. J. M., van Riet, E. E., van Mourik, Y., Brunner-La Rocca, H. P., Linssen, G. C. M., Hoes, A. W., Bots, M. L., den Ruijter, H. M., & Rutten, F. H. (2022). Heart failure with preserved, mid-range, and reduced ejection fraction across health care settings: an observational study. Esc heart failure, 9(1), 363-372. https://doi.org/10.1002/ehf2.13742
    • Ament, S. M. C., van den Broek, L. M., Van den Beuken-van Everdingen, M. H. J., Boyne, J. J. J., Maessen, J. M. C., Bekkers, S. C. A. M., Bellersen, L., Brunner-La Rocca, H. P., Engels, Y., & Janssen, D. J. A. (2022). What to consider when implementing a tool for timely recognition of palliative care needs in heart failure: a context-based qualitative study. BMC Palliative Care, 21(1), Article 1. https://doi.org/10.1186/s12904-021-00896-y
    • Vergaro, G., Aimo, A., Januzzi, J. L., Richards, A. M., Lam, C. S. P., Latini, R., Staszewsky, L., Anand, I. S., Ueland, T., Brunner-La Rocca, H.-P., Bayes-Genis, A., Lupón, J., de Boer, R. A., Yoshihisa, A., Takeishi, Y., Gustafsson, I., Eggers, K. M., Huber, K., Gamble, G. D., ... Passino, C. (2022). Cardiac biomarkers retain prognostic significance in patients with heart failure and chronic obstructive pulmonary disease. Journal of Cardiovascular Medicine, 23(1), 28-36. https://doi.org/10.2459/JCM.0000000000001281
    • Baldewijns, K., Boyne, J., de Maesschalck, L., Deville, A., Brandenburg, V., & Brunner-La-Rocca, H. P. (2022). From guideline to daily practice: Implementation of ESC-guidelines considering multidisciplinary and non-pharmacological care in heart failure in three ESC member states, a case study. JRSM Cardiovascular Disease, 11, 1-7. https://doi.org/10.1177/20480040221074598
    • Weerts, J., Barandiarán Aizpurua, A., Henkens, M. T. H. M., Lyon, A., van Mourik, M. J. W., van Gemert, M. R. A. A., Raafs, A., Sanders-van Wijk, S., Bayés-Genís, A., Heymans, S. R. B., Crijns, H. J. G. M., Brunner-La Rocca, H.-P., Lumens, J., van Empel, V. P. M., & Knackstedt, C. (2022). The prognostic impact of mechanical atrial dysfunction and atrial fibrillation in heart failure with preserved ejection fraction. European Heart Journal Cardiovascular Imaging, 23(1), 74-84. https://doi.org/10.1093/ehjci/jeab222
  • 2021
    • Ferreira, J. P., Girerd, N., Brunner-La Rocca, H. P., Pellicori, P., Cleland, J. G., Rossignol, P., & Zannad, F. (2021). No influence of spironolactone on plasma concentrations of angiotensin-converting enzyme 2: Findings from the HOMAGE randomized trial. Archives of Cardiovascular Diseases, 114(12), 814-817. https://doi.org/10.1016/j.acvd.2021.10.003
    • Scherrenberg, M., Storms, V., van der Velde, A. E., Boyne, J., Bruins, W., Vranken, J., Leenen, J. P. L., Brunner-La Rocca, H.-P., De Kluiver, E. P., & Dendale, P. (2021). A Home Hospitalisation Strategy for Patients with an Acute Episode of Heart Failure Using a Digital Health-Supported Platform: A Multicentre Feasibility Study - A Rationale and Study Design. Cardiology, 146(6), 793-800. https://doi.org/10.1159/000519085
    • Lumbers, R. T., Shah, S., Lin, H. H., Czuba, T., Henry, A., Swerdlow, D. I., Malarstig, A., Andersson, C., Verweij, N., Holmes, M. V., Arnlov, J., Svensson, P., Hemingway, H., Sallah, N., Almgren, P., Aragam, K. G., Asselin, G., Backman, J. D., Biggs, M. L., ... Regeneron Genetics Ctr (2021). The genomics of heart failure: design and rationale of the HERMES consortium. Esc heart failure, 8(6), 5531–5541. https://doi.org/10.1002/ehf2.13517
    • Anker, S. D., Butler, J., Filippatos, G., Ferreira, J. P., Bocchi, E., Bohm, M., Brunner-La Rocca, H. P., Choi, D. J., Chopra, V., Chuquiure-Valenzuela, E., Giannetti, N., Gomez-Mesa, J. E., Janssens, S., Januzzi, J. L., Gonzalez-Juanatey, J. R., Merkely, B., Nicholls, S. J., Perrone, S. V., Pina, I. L., ... EMPEROR-Preserved Trial Investigators (2021). Empagliflozin in Heart Failure with a Preserved Ejection Fraction. New England Journal of Medicine, 385(16), 1451-1461. https://doi.org/10.1056/NEJMoa2107038
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