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ERC Advanced Grant awarded to Prof. Andy Baker

ERC Advanced Grant awarded to Prof. Andy Baker

15 April 2024

Prof. Andy Baker (Dept of Pathology) has been awarded a European Research Council (ERC) Advanced Grant of €2,5M for his research project PolymiRize: Poly-miRNA targeting to prevent and reverse complex tissue remodelling after acute cardiovascular events'.

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Longer and better lives for patients with atrial fibrillation

Longer and better lives for patients with atrial fibrillation

15 April 2024

An international panel of experts published recommendations to improve management of atrial fibrillation (AF).

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Carim Maastricht
Carim Maastricht

Twan van Stipdonk

Post doc

Dr Twan van Stipdonk studied medicine at the Maastricht University. After finishing his general medicine study, he went on to do his training in clinical cardiology. During his clinical training, he worked on the Dutch guideline for cardiac rehabilitation (2011), and later he started his PhD in the field of Cardiac Resynchronisation Therapy. Under the guidance of Prof. Frits Prinzen, Prof. Harry Crijns and Prof. Kevin Vernooy, he finished his PhD in 2019. He currently works as a heart failure and devices cardiologist at the Department of Cardiology of Maastricht UMC+. His research focusses on crossing the borders of electrophysiology and heart failure, the field of ‘electrical management of heart failure’.

 

Twan-van-stipdonk

Department of Cardiology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: Cardiology department level 3
T: +31(0)43 387 71 19

  • 2024
    • Nguyên, U. C., Rijks, J. H. J., Plesinger, F., Rademakers, L. M., Luermans, J., Smits, K. C., van Stipdonk, A. M. W., Prinzen, F. W., Vernooy, K., Halamek, J., Curila, K., & Jurak, P. (2024). Ultra-High-Frequency ECG in Cardiac Pacing and Cardiac Resynchronization Therapy: From Technical Concept to Clinical Application. Journal of Cardiovascular Development and Disease, 11(3), Article 76. https://doi.org/10.3390/jcdd11030076
    • Herweg, B., Sharma, P. S., Cano, O., Ponnusamy, S. S., Zanon, F., Jastrzebski, M., Zou, J., Chelu, M. G., Vernooy, K., Whinnett, Z. I., Nair, G. M., Molina-Lerma, M., Curila, K., Zalavadia, D., Dye, C., Vipparthy, S. C., Brunetti, R., Mumtaz, M., Moskal, P., ... Vijayaraman, P. (2024). Arrhythmic Risk In Biventricular Pacing Compared with Left Bundle Branch Area Pacing: Results From The International LBBAP Collaborative Study (I-CLAS). Circulation, 149(5), 379-390. https://doi.org/10.1161/CIRCULATIONAHA.123.067465
    • Eerenberg, F., Luermans, J., Lumens, J., Nguyên, U. C., Vernooy, K., & van Stipdonk, A. (2024). Exploring QRS Area beyond Patient Selection in CRT-Can It Guide Left Ventricular Lead Placement?Journal of Cardiovascular Development and Disease, 11(1). https://doi.org/10.3390/jcdd11010018
    • Dural, M., Ghossein, M. A., Gerrits, W., Daniels, F., Meine, M., Maass, A. H., Rienstra, M., Prinzen, F. W., Vernooy, K., & van Stipdonk, A. M. W. (2024). Association of vectorcardiographic T-wave area with clinical and echocardiographic outcomes in cardiac resynchronization therapy. EP Europace, 26(1), Article euad370. https://doi.org/10.1093/europace/euad370
  • 2023
    • Varma, N., Parreira, L., Tsyganov, A., Artyukhina, E., Vernooy, K., Tondo, C., Ascione, C., Carvalho, S., Egger, M., Holm, M., Shapieva, A., van Stipdonk, A., Taymasova, I., Zubarev, S., & Auricchio, A. (2023). Activation time at the left ventricular pacing site (QLV) relative to the actual site of latest activation-Implications for response to cardiac resynchronization therapy. Heart Rhythm, 20(8), 1199-1201. https://doi.org/10.1016/j.hrthm.2023.04.017
    • Vijayaraman, P., Sharma, P. S., Cano, O., Ponnusamy, S. S., Herweg, B., Zanon, F., Jastrzebski, M., Zou, J., Chelu, M. G., Vernooy, K., Whinnett, Z. I., Nair, G. M., Molina-Lerma, M., Curila, K., Zalavadia, D., Haseeb, A., Dye, C., Vipparthy, S. C., Brunetti, R., ... Ellenbogen, K. A. (2023). Comparison of Left Bundle Branch Area Pacing and Biventricular Pacing in Candidates for Resynchronization Therapy. Journal of the American College of Cardiology, 82(3), 228-241. https://doi.org/10.1016/j.jacc.2023.05.006
    • Rijks, J. H. J., Lankveld, T., Manusama, R., Broers, B., van Stipdonk, A. M. W., Chaldoupi, S. M., ter Bekke, R. M. A., Schotten, U., Linz, D., Luermans, J. G. L. M., & Vernooy, K. (2023). Left Bundle Branch Area Pacing and Atrioventricular Node Ablation in a Single-Procedure Approach for Elderly Patients with Symptomatic Atrial Fibrillation. Journal of Clinical Medicine, 12(12), Article 4028. https://doi.org/10.3390/jcm12124028
    • Assa, S., Vernooy, K., & van Stipdonk, A. M. W. (2023). Cardiovascular Implantable Electronic Devices Enabled Remote Heart Failure Monitoring; What We Have Learned and Where to Go Next. Journal of Cardiovascular Development and Disease, 10(4), Article 152. https://doi.org/10.3390/jcdd10040152
    • Parreira, L., Tsyganov, A., Artyukhina, E., Vernooy, K., Tondo, C., Adragao, P., Ascione, C., Carmo, P., Carvalho, S., Egger, M., Ferreira, A., Ghossein, M., Holm, M., Kalinin, V., Malakhova, M., Meine, M., Nunes, S., Podolyak, D., Revishvili, A., ... Varma, N. (2023). Non-invasive three-dimensional electrical activation mapping to predict cardiac resynchronization therapy response: site of latest left ventricular activation relative to pacing site. EP Europace, 25(4), 1458-1466. https://doi.org/10.1093/europace/euad041
    • Rijks, J., Ghossein, M. A., Wouters, P. C., Dural, M., Maass, A. H., Meine, M., Kloosterman, M., Luermans, J., Prinzen, F. W., Vernooy, K., & van Stipdonk, A. M. W. (2023). Comparison of the relation of the ESC 2021 and ESC 2013 definitions of left bundle branch block with clinical and echocardiographic outcome in cardiac resynchronization therapy. Journal of Cardiovascular Electrophysiology, 34(4), 1006-1014. https://doi.org/10.1111/jce.15882
    • Wouters, P. C., van de Leur, R. R., Vessies, M. B., van Stipdonk, A. M. W., Ghossein, M. A., Hassink, R. J., Doevendans, P. A., van der Harst, P., Maass, A. H., Prinzen, F. W., Vernooy, K., Meine, M., & van Es, R. (2023). Electrocardiogram-based deep learning improves outcome prediction following cardiac resynchronization therapy. European Heart Journal, 44(8), 680–692. https://doi.org/10.1093/eurheartj/ehac617
    • Luker, J., Strik, M., Andrade, J. G., Raymond-Paquin, A., Elrefai, M. H., Roberts, P. R., Perez, O. C., Kron, J., Koneru, J., Franqui-Rivera, H., Sultan, A., Ernst, A., Schmitt, J., Pott, A., Veltmann, C., Srinivasan, N. T., Collinson, J., van Stipdonk, A. M. W., Linz, D., ... Steven, D. (2023). Incidence of premature battery depletion in subcutaneous cardioverter-defibrillator patients: insights from a multicenter registry. Journal of Interventional Cardiac Electrophysiology. Advance online publication. https://doi.org/10.1007/s10840-023-01468-1
  • 2022
    • van Stipdonk, A. M. W., Schretlen, S., Dohmen, W., Knackstedt, C., Beckers-Wesche, F., Debie, L., Brunner-La Rocca, H.-P., & Vernooy, K. (2022). Better outcome at lower costs after implementing a CRT-care pathway: comprehensive evaluation of real-world data. Esc heart failure, 9(4), 2518-2527. https://doi.org/10.1002/ehf2.13958
    • Henkens, M. T. H. M., Martinez, H. L., Weerts, J., Sammani, A., Raafs, A. G., Verdonschot, J. A. J., van de Leur, R. R., Sikking, M. A., Stroeks, S., van Empel, V. P. M., Brunner-La Rocca, H. P., van Stipdonk, A. M. W., Farmakis, D., Hazebroek, M. R., Vernooy, K., Bayes-de-Luna, A., Asselbergs, F. W., Bayes-Genis, A., & Heymans, S. R. B. (2022). Interatrial Block Predicts Life-Threatening Arrhythmias in Dilated Cardiomyopathy. Journal of the American Heart Association, 11(14), Article e025473. https://doi.org/10.1161/JAHA.121.025473
    • Rijks, J., Luermans, J., Heckman, L., van Stipdonk, A. M. W., Prinzen, F., Lumens, J., & Vernooy, K. (2022). Physiology of Left Ventricular Septal Pacing and Left Bundle Branch Pacing. Cardiac Electrophysiology Clinics, 14(2), 181-189. https://doi.org/10.1016/j.ccep.2021.12.010
    • Salden, F. C. W. M., Huntjens, P. R., Schreurs, R., Willemen, E., Kuiper, M., Wouters, P., Maessen, J. G., Bordachar, P., Delhaas, T., Luermans, J., Meine, M., Allaart, C. P., van Stipdonk, A. M. W., Prinzen, F. W., Lumens, J., & Vernooy, K. (2022). Pacing therapy for atrioventricular dromotropathy: a combined computational-experimental-clinical study. EP Europace, 24(5), 784-795. https://doi.org/10.1093/europace/euab248
    • Ghossein, M. A., Driessen, R. G. H., van Rosmalen, F., Sels, J.-W. E. M., Delnoij, T., Geyik, Z., Mingels, A. M. A., van Stipdonk, A. M. W., Prinzen, F. W., Ghossein-Doha, C., van Kuijk, S. M. J., van der Horst, I. C. C., Vernooy, K., & van Bussel, B. C. T. (2022). Serial Assessment of Myocardial Injury Markers in Mechanically Ventilated Patients With SARS-CoV-2 (from the Prospective MaastrICCht Cohort). American Journal of Cardiology, 170, 118-127. https://doi.org/10.1016/j.amjcard.2022.01.030
    • Heckman, L. I. B., Luermans, J. G. L. M., Jastrzębski, M., Weijs, B., Van Stipdonk, A. M. W., Westra, S., den Uijl, D., Linz, D., Mafi-Rad, M., Prinzen, F. W., & Vernooy, K. (2022). A single-centre prospective evaluation of left bundle branch area pacemaker implantation characteristics. Netherlands Heart Journal, 30(5), 249-257. https://doi.org/10.1007/s12471-022-01679-7
    • Henkens, M. T. H. M., Weerts, J., Verdonschot, J. A. J., Raafs, A. G., Stroeks, S., Sikking, M. A., Amin, H., Mourmans, S. G. J., Geraeds, C. B. G., Sanders-van Wijk, S., Aizpurua, A. B., Uszko-Lencer, N. H. M. K., Krapels, I. P. C., Wolffs, P. F. G., Brunner, H. G., Leeuwen, R. E. W., Verhesen, W., Schalla, S. M., van Stipdonk, A. W. M., ... Heymans, S. R. B. (2022). Improving diagnosis and risk stratification across the ejection fraction spectrum: the Maastricht Cardiomyopathy registry. Esc heart failure, 9(2), 1463-1470. https://doi.org/10.1002/ehf2.13833
    • Ghossein, M. A., van Stipdonk, A. M., Prinzen, F. W., & Vernooy, K. (2022). Vectorcardiographic QRS area as a predictor of response to cardiac resynchronization therapy. Journal of Geriatric Cardiology, 19(1), 9-20. https://doi.org/10.11909/j.issn.1671-5411.2022.01.003
  • 2021
    • Ghossein, M. A., Zanon, F., Salden, F., van Stipdonk, A., Marcantoni, L., Engels, E., Luermans, J., Westra, S., Prinzen, F., & Vernooy, K. (2021). Left Ventricular Lead Placement Guided by Reduction in QRS Area. Journal of Clinical Medicine, 10(24), Article 5935. https://doi.org/10.3390/jcm10245935
    • Dural, M., van Stipdonk, A. M. W., Salden, F. C. W. M., Ter Horst, I., Crijns, H. J. G. M., Meine, M., Maass, A. H., Kloosterman, M., & Vernooy, K. (2021). Association of ECG characteristics with clinical and echocardiographic outcome to CRT in a non-LBBB patient population. Journal of Interventional Cardiac Electrophysiology, 62(1), 9-19. https://doi.org/10.1007/s10840-020-00866-z
    • Heckman, L., Luermans, J., Salden, F., van Stipdonk, A. M. W., Mafi-Rad, M., Prinzen, F., & Vernooy, K. (2021). Physiology and Practicality of Left Ventricular Septal Pacing. Arrhythmia & Electrophysiology Review, 10(3), 165-171. https://doi.org/10.15420/aer.2021.21
    • van Stipdonk, A. M. W., Schretlen, S., Dohmen, W., Brunner-LaRocca, H. P., Knackstedt, C., & Vernooy, K. (2021). Development and implementation of a cardiac resynchronisation therapy care pathway: improved process and reduced resource use. BMJ Open Quality, 10(1), Article e001072. https://doi.org/10.1136/bmjoq-2020-001072
    • Ghossein, M. A., van Stipdonk, A. M. W., Plesinger, F., Kloosterman, M., Wouters, P. C., Salden, O. A. E., Meine, M., Maass, A. H., Prinzen, F. W., & Vernooy, K. (2021). Reduction in the QRS area after cardiac resynchronization therapy is associated with survival and echocardiographic response. Journal of Cardiovascular Electrophysiology, 32(3), 813-822. https://doi.org/10.1111/jce.14910
    • Heckman, L. I. B., Luermans, J. G. L. M., Curila, K., Van Stipdonk, A. M. W., Westra, S., Smisek, R., Prinzen, F. W., & Vernooy, K. (2021). Comparing Ventricular Synchrony in Left Bundle Branch and Left Ventricular Septal Pacing in Pacemaker Patients. Journal of Clinical Medicine, 10(4), Article 822. https://doi.org/10.3390/jcm10040822
    • Salden, O. A. E., van Stipdonk, A. M. W., den Ruijter, H. M., Cramer, M. J., Kloosterman, M., Rienstra, M., Maass, A. H., Prinzen, F. W., Vernooy, K., & Meine, M. (2021). Heart Size Corrected Electrical Dyssynchrony and Its Impact on Sex-Specific Response to Cardiac Resynchronization Therapy. Circulation-Arrhythmia and Electrophysiology, 14(1), Article 008452. https://doi.org/10.1161/CIRCEP.120.008452
  • 2020
    • Heckman, L., Vijayaraman, P., Luermans, J., Stipdonk, A. M. W., Salden, F., Maass, A. H., Prinzen, F. W., & Vernooy, K. (2020). Novel bradycardia pacing strategies. Heart, 106(24), 1883-1889. https://doi.org/10.1136/heartjnl-2020-316849
    • Verdonschot, J. A. J., Merken, J. J., van Stipdonk, A. M. W., Pliger, P., Derks, K. W. J., Wang, P., Henkens, M. T. H. M., van Paassen, P., Hamid, M. A. A., van Empel, V. P. M., Knackstedt, C., Luermans, J. G. L. M., Crijns, H. J. G. M., Brunner-La Rocca, H.-P., Brunner, H. G., Poelzl, G., Vernooy, K., Heymans, S. R. B., & Hazebroek, M. R. (2020). Cardiac Inflammation Impedes Response to Cardiac Resynchronization Therapy in Patients With Idiopathic Dilated Cardiomyopathy. Circulation-Arrhythmia and Electrophysiology, 13(11), 1311-1320. Article 008727. https://doi.org/10.1161/circep.120.008727
    • Kloosterman, M., van Stipdonk, A. M. W., ter Horst, I., Rienstra, M., Van Gelder, I. C., Vos, M. A., Prinzen, F. W., Meine, M., Vernooy, K., & Maass, A. H. (2020). Association between heart failure aetiology and magnitude of echocardiographic remodelling and outcome of cardiac resynchronization therapy. Esc heart failure, 7(2), 645-653. https://doi.org/10.1002/ehf2.12624
    • van Stipdonk, A. M. W., Hoogland, R., Ter Horst, I., Kloosterman, M., Vanbelle, S., Crijns, H. J. G. M., Prinzen, F. W., Meine, M., Maass, A. H., & Vernooy, K. (2020). Evaluating Electrocardiography-Based Identification of Cardiac Resynchronization Therapy Responders Beyond Current Left Bundle Branch Block Definitions. JACC: Clinical Electrophysiology, 6(2), 193-203. https://doi.org/10.1016/j.jacep.2019.10.009
    • Salden, O. A. E., Vernooy, K., van Stipdonk, A. M. W., Cramer, M. J., Prinzen, F. W., & Meine, M. (2020). Strategies to Improve Selection of Patients Without Typical Left Bundle Branch Block for Cardiac Resynchronization Therapy. JACC: Clinical Electrophysiology, 6(2), 129-142. https://doi.org/10.1016/j.jacep.2019.11.018
    • Plesinger, F., van Stipdonk, A. M. W., Smisek, R., Halamek, J., Jurak, P., Maass, A. H., Meine, M., Vernooy, K., & Prinzen, F. W. (2020). Fully automated QRS area measurement for predicting response to cardiac resynchronization therapy. Journal of Electrocardiology, 63, 159-163. https://doi.org/10.1016/j.jelectrocard.2019.07.003
  • 2019
    • van Stipdonk, A. M. W., Vanbelle, S., ter Horst, I. A. H., Luermans, J. G., Meine, M., Maass, A. H., Auricchio, A., Prinzen, F. W., & Vernooy, K. (2019). Large variability in clinical judgement and definitions of left bundle branch block to identify candidates for cardiac resynchronisation therapy. International Journal of Cardiology, 286, 61-65. https://doi.org/10.1016/j.ijcard.2019.01.051
    • van Stipdonk, A. M. W., ter Horst, I., Kloosterman, M., Engels, E. B., Rienstra, M., Crijns, H. J. G. M., Vos, M. A., van Gelder, I. C., Prinzen, F. W., Meine, M., Maass, A., & Vernooy, K. (2019). Response to Letter From Vereckei Regarding, "QRS Area Is a Strong Determinant of Outcome in Cardiac Resynchronization Therapy". Circulation-Arrhythmia and Electrophysiology, 12(4), Article 007297. https://doi.org/10.1161/CIRCEP.119.007297
  • 2018
    • van Stipdonk, A. M. W., ter Horst, I., Kloosterman, M., Engels, E. B., Rienstra, M., Crijns, H. J. G. M., Vos, M. A., van Gelder, I. C., Prinzen, F. W., Meine, M., Maass, A. H., & Vernooy, K. (2018). QRS Area Is a Strong Determinant of Outcome in Cardiac Resynchronization Therapy. Circulation-Arrhythmia and Electrophysiology, 11(12), Article 006497. https://doi.org/10.1161/CIRCEP.118.006497
    • Caputo, M. L., van Stipdonk, A., Illner, A., D'Ambrosio, G., Regoli, F., Conte, G., Moccetti, T., Klersy, C., Prinzen, F. W., Vernooy, K., & Auricchio, A. (2018). The definition of left bundle branch block influences the response to cardiac resynchronization therapy. International Journal of Cardiology, 269, 165-169. https://doi.org/10.1016/j.ijcard.2018.07.060
    • Engels, E. B., Mafi-Rad, M., Hermans, B. J. M., Aranda, A., van Stipdonk, A. M. W., Rienstra, M., Scheerder, C. O. S., Maass, A. H., Prinzen, F. W., & Vernooy, K. (2018). Tailoring device settings in cardiac resynchronization therapy using electrograms from pacing electrodes. EP Europace, 20(7), 1146-1153. https://doi.org/10.1093/europace/eux208
  • 2016
    • Engels, E. B., Mafi-Rad, M., van Stipdonk, T., Vernooy, K., & Prinzen, F. W. (2016). Why QRS Duration Should Be Replaced by Better Measures of Electrical Activation to Improve Patient Selection for Cardiac Resynchronization Therapy. Journal of Cardiovascular Translational Research, 9(4), 257-265. https://doi.org/10.1007/s12265-016-9693-1
    • van Stipdonk, A. M. W., Rad, M. M., Luermans, J. G. L. M., Crijns, H. J., Prinzen, F. W., & Vernooy, K. (2016). Identifying delayed left ventricular lateral wall activation in patients with non-specific intraventricular conduction delay using coronary venous electroanatomical mapping. Netherlands Heart Journal, 24(1), 58-65. https://doi.org/10.1007/s12471-015-0777-3
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