Pilz, S., Henry, R. M., Snijder, M. B., van Dam, R. M., Nijpels, G., Stehouwer, C. D. A., Kamp, O., Tomaschitz, A., Pieber, T. R., & Dekker, J. M. (2010). Vitamin D deficiency and myocardial structure and function in older men and women: The Hoorn Study.Journal of Endocrinological Investigation, 33(9), 612-617. https://doi.org/10.1007/BF03346658

Segers, O., van Oerle, R., ten Cate, H., Rosing, J., & Castoldi, E. (2010). Thrombin generation as an intermediate phenotype for venous thrombosis A proof-of-concept study. Thrombosis and Haemostasis, 103(1), 114-122. https://doi.org/10.1160/TH09-06-0356

Kooter, I. M., Gerlofs-Nijland, M. E., Boere, A. J. F., Leseman, D. L. A. C., Fokkens, P. H. B., Spronk, H. M. H., Frederix, K., Ten Cate, H., Knaapen, A. M., Vreman, H. J., & Cassee, F. R. (2010). Diesel engine exhaust initiates a sequence of pulmonary and cardiovascular effects in rats. Journal of Toxicology, 2010, 206057. https://doi.org/10.1155/2010/206057

Van de Vijver, P., Suylen, D. P., Dirksen, A., Dawson, P. E., & Hackeng, T. M. (2010). N-epsilon-(Thiaprolyl)-lysine as a Handle for Site-Specific Protein Conjugation. Biopolymers, 94(4), 465-474. https://doi.org/10.1002/bip.21485

Oostendorp, M., Douma, K., Hackeng, T. M., van Zandvoort, M. A. M. J., Post, M. J., & Backes, W. H. (2010). Pharmacokinetics of contrast agents targeted to the tumor vasculature in molecular magnetic resonance imaging. Contrast Media & Molecular Imaging, 5(1), 9-17. https://doi.org/10.1002/cmmi.361

Senen, K., Topal, E., Kilinc, E., ten Cate, H., Tek, I., Karakoc, Y., & Yetkin, E. (2010). Plasma viscosity and mean platelet volume in patients undergoing coronary angiography. Clinical Hemorheology and Microcirculation, 44(1), 35-41. https://doi.org/10.3233/CH-2010-1249

Loubele, S. T. B. G., Spek, C. A., Leenders, P., van Oerle, R., Aberson, H. L., van der Voort, D., Hamulyák, K., Petersen, L. C., Spronk, H. M. H., & ten Cate, H. (2009). Active site inhibited factor VIIa attenuates myocardial ischemia/reperfusion injury in mice. Journal of Thrombosis and Haemostasis, 7(2), 290-8. https://doi.org/10.1111/j.1538-7836.2008.03232.x

Pilz, S., Henry, R. M., Snijder, M. B., van Dam, R. M., Nijpels, G., Stehouwer, C. D., Tomaschitz, A., Pieber, T. R., & Dekker, J. M. (2009). 25-Hydroxyvitamin D is not Associated with Carotid Intima-Media Thickness in Older Men and Women. Calcified Tissue International, 84(5), 423-424. https://doi.org/10.1007/s00223-009-9238-6

Klomp, C. M., ten Cate, H., Stehouwer, C. D., & Schaper, N. C. (2009). Acetylsalicylzuur bij patienten met diabetes mellitus: niet voor primaire, wel voor secundaire preventie van hart-vaatziekten. Nederlands Tijdschrift voor Geneeskunde, 153, A109. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19785798

Wijnen, P. A., Limantoro, I., Drent, M., Bekers, O., Kuijpers, P. M., & Koek, G. H. (2009). Depressive effect of an antidepressant: therapeutic failure of venlafaxine in a case lacking CYP2D6 activity. Annals of Clinical Biochemistry, 46(Pt 6), 527-30. https://doi.org/10.1258/acb.2009.009003

Wolfs, J. L., Comfurius, P., Bekers, O., Zwaal, R. F., Balasubramanian, K., Schroit, A. J., Lindhout, T., & Bevers, E. M. (2009). Direct inhibition of phospholipid scrambling activity in erythrocytes by potassium ions. Cellular and Molecular Life Sciences, 66(2), 314-23. https://doi.org/10.1007/s00018-008-8566-4

Lind, J. S., Postmus, P. E., Heideman, D. A., Thunnissen, E. B., Bekers, O., & Smit, E. F. (2009). Dramatic response to low-dose erlotinib of epidermal growth factor receptor mutation-positive recurrent non-small cell lung cancer after severe cutaneous toxicity. Journal of Thoracic Oncology, 4(12), 1585-6. https://doi.org/10.1097/JTO.0b013e3181bbb2b9

Jacobs, L. H., van de Kerkhof, J., Mingels, A. M., Kleijnen, V. W., van der Sande, F. M., Wodzig, W. K., Kooman, J. P., & van Dieijen-Visser, M. P. (2009). Haemodialysis patients longitudinally assessed by highly sensitive cardiac troponin T and commercial cardiac troponin T and cardiac troponin I assays.Annals of Clinical Biochemistry, 46(Pt 4), 283-290. https://doi.org/10.1258/acb.2009.008197

Miserus, R. J., Herias, M. V., Prinzen, L., Lobbes, M. B., van Suylen, R. J., Dirksen, A., Hackeng, T. M., Heemskerk, J. W., van Engelshoven, J. M., Daemen, M. J. A. P., van Zandvoort, M. A. M. J., Heeneman, S., & Kooi, M. E. (2009). Molecular MRI of early thrombus formation using a bimodal alpha2-antiplasmin-based contrast agent. JACC-Cardiovascular Imaging, 2(8), 987-96. https://doi.org/10.1016/j.jcmg.2009.03.015

Wijnen, P. A. H. M., Drent, M., van Dieijen-Visser, M. P., & Bekers, O. (2009). Pharmacogenetic testing after a simple DNA isolation method on buccal swab samples. Pharmacogenomics, 10(6), 983-7. https://doi.org/10.2217/pgs.09.4

Henry, R. M., Ferreira, I., Dekker, J. M., Nijpels, G., Scheffer, P. G., & Stehouwer, C. D. (2009). The metabolic syndrome in elderly individuals is associated with greater muscular, but not elastic arterial stiffness, independent of low-grade inflammation, endothelial dysfunction or insulin resistance-The Hoorn Study. Journal of Human Hypertension, 23(11), 718-727. https://doi.org/10.1038/jhh.2009.8

Miserus, R., Dirksen, A., Suylen, D. P., Herias, V., Prinzen, L., van Zandvoort, M. A. M. J., Kooi, M. E., Dawson, P., Heeneman, S., Daemen, M. J., & Hackeng, T. M. (2009). Total Chemical Synthesis of Bimodal-Labeled Rantes as a Pet/Tplsm Probe for in Vivo Molecular Imaging of Atherosclerotic Plaque Instability. Biopolymers, 92(4), 376-376. http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ResearchSoft&SrcApp=EndNote&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000266753100412

Kuijpers, M., Gilio, K., Reitsma, S., Unal - Nergiz, R., Prinzen, L., Heeneman, S., Lutgens, E., van Zandvoort, M., Nieswandt, B., Oude Egbrink, M., & Heemskerk, J. (2009). Complementary roles of platelets and coagulation in thrombus formation on plaques acutely ruptured by targeted ultrasound treatment: a novel intravital model. Journal of Thrombosis and Haemostasis, 7(1), 152-161. https://doi.org/10.1111/j.1538-7836.2008.03186.x

Frederix, K., Kooter, I. M., van Oerle, R., Fens, D., Hamulyak, K., Gerlofs-Nijland, M. E., Ten Cate, H., & Spronk, H. M. (2008). A new method to determine tissue specific tissue factor thrombomodulin activities: endotoxin and particulate air pollution induced disbalance. Thrombosis Journal, 6, 14. https://doi.org/10.1186/1477-9560-6-14

Oostendorp, M., Douma, K., Hackeng, T. M., Dirksen, A., Post, M. J., van Zandvoort, M. A. M., & Backes, W. H. (2008). Quantitative molecular magnetic resonance imaging of tumor angiogenesis using cNGR-labeled paramagnetic quantum dots. Cancer Research, 68(18), 7676-7683. https://doi.org/10.1158/0008-5472.CAN-08-0689

Dielis, A. W. J. H., Balliël, W. M. R., van Oerle, R., Hermens, W. T., Spronk, H. M. H., Ten Cate, H., & Hamulyak, K. (2008). Thrombomodulin-modified thrombin generation after in vivo recombinant factor VIII treatment in severe hemophilia A. Haematologica-the Hematology Journal, 93(9), 1351-7. https://doi.org/10.3324/haematol.13039

Hermans, M. M., Henry, R. M., Dekker, J. M., Nijpels, G., Heine, R. J., & Stehouwer, C. D. (2008). Albuminuria, but not estimated glomerular filtration rate, is associated with maladaptive arterial remodeling: the Hoorn Study. Journal of Hypertension, 26(4), 791-7. https://doi.org/10.1097/HJH.0b013e3282f50066

Vanschoonbeek, K., Wouters, K., van der Meijden, P. E., van Gorp, P. J. J., Feijge, M. A., Herfs, M., Schurgers, L. J., Hofker, M. H., de Maat, M. P., & Heemskerk, J. W. (2008). Anticoagulant effect of dietary fish oil in hyperlipidemia: a study of hepatic gene expression in APOE2 knock-in mice.Arteriosclerosis Thrombosis and Vascular Biology, 28(11), 2023-2029. https://doi.org/10.1161/ATVBAHA.107.156992

Stehouwer, C. D. A., Henry, R. M. A., & Ferreira, I. (2008). Arterial stiffness in diabetes and the metabolic syndrome: a pathway to cardiovascular disease. Diabetologia, 51(4), 527-539. https://doi.org/10.1007/s00125-007-0918-3

Linssen, C. F. M., Bekers, O., Drent, M., & Jacobs, J. A. (2008). C-reactive protein and procalcitonin concentrations in bronchoalveolar lavage fluid as a predictor of ventilator-associated pneumonia. Annals of Clinical Biochemistry, 45(Pt 3), 293-8. https://doi.org/10.1258/acb.2007.007133

van Schaik, R. H. N., Grandia, L., de Goede, A., Bet, P. M., Bekers, O., Guchelaar, H. J., Goldschmidt, H. M. J., Meijer, M. M. C., Mulder, H., van der Weide, J., & Deneer, V. H. M. (2008). CYP2D6 genotype `1-0' ingedeeld als intermediaire metaboliseerder.Nederlands tijdschrift voor klinische chemie en laboratoriumgeneeskunde, 33(1), 52.

Wijnen, P. A. H. M., op den Buijsch, R. A., Cheung, S. C., van der Heijden, J., Hoogtanders, K., Stolk, L. M. L., van Dieijen-Visser, M., Neef, C. K., Drent, M., & Bekers, O. (2008). Genotyping with a dried blood spot method: a useful technique for application in pharmacogenetics. Clinica Chimica Acta, 388(1-2), 189-91. https://doi.org/10.1016/j.cca.2007.10.001

Wijnen, P. A. H. M., Drent, M., Nelemans, P. J., Kuijpers, P. M., Koek, G. H., Neef, C. K., Haenen, G. R., & Bekers, O. (2008). Role of cytochrome p450 polymorphisms in the development of pulmonary drug toxicity: a case-control study in the Netherlands. Drug Safety, 31(12), 1125-34. https://doi.org/10.2165/0002018-200831120-00008

Ramakers, I. H. G. B., Visser, P. J., Aalten, P., Bekers, O., Sleegers, K., van Broeckhoven, C. L., Jolles, J., & Verhey, F. R. (2008). The association between APOE genotype and memory dysfunction in subjects with mild cognitive impairment is related to age and Alzheimer pathology. Dementia and Geriatric Cognitive Disorders, 26(2), 101-8. https://doi.org/10.1159/000144072

Cranenburg, E. C., Vermeer, C., Koos, R., Boumans, M. L., Hackeng, T. M., Bouwman, F. G., Kwaijtaal, M., Brandenburg, V. M., Ketteler, M., & Schurgers, L. J. (2008). The circulating inactive form of matrix Gla Protein (ucMGP) as a biomarker for cardiovascular calcification. Journal of Vascular Research, 45(5), 427-36. https://doi.org/10.1159/000124863

Meex, S. J., van Vliet-Ostaptchouk, J. V., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Schalkwijk, C. G., Feskens, E. J. M., Blaak, E. E., Wijmenga, C., Hofker, M. H., Stehouwer, C. D., & de Bruin, T. W. (2008). Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: Association study in 2000 Dutch Caucasians. Molecular Genetics and Metabolism, 94(3), 352-355. https://doi.org/10.1016/j.ymgme.2008.03.011

Megens, R. T. A., Oude Egbrink, M. G. A., Cleutjens, J. P. M., Kuijpers, M. J. E., Schiffers, P. H. M., Merkx, M., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2007). Imaging collagen in intact viable healthy and atherosclerotic arteries using fluorescently labeled CNA35 and two-photon laser scanning microscopy. Molecular Imaging, 6(4), 247-60. https://doi.org/10.2310/7290.2007.00021

Dielis, A. W. J. H., Smid, M., Spronk, H. M. H., Houben, A. J. H. M., Hamulyák, K., Kroon, A. A., Ten Cate, H., & de Leeuw, P. W. (2007). Changes in fibrinolytic activity after angiotensin II receptor blockade in therapy-resistant hypertensive patients. Journal of Thrombosis and Haemostasis, 5(7), 1509-15. https://doi.org/10.1111/j.1538-7836.2007.02577.x

Aerts, H. J. W. L., Dubois, L., Hackeng, T. M., Straathof, R., Chiu, R. K., Lieuwes, N. G., Jutten, B., Weppler, S. A., Lammering, G., Wouters, B. G., & Lambin, P. (2007). Development and evaluation of a cetuximab-based imaging probe to target EGFR and EGFRvIII. Radiotherapy and Oncology, 83(3), 326-332. https://doi.org/10.1016/j.radonc.2007.04.030

Koenen, R. R., von Hundelshausen, P., & Weber, C. (2007). Inflammatory blues turns velvet skin into rawhide: monocyte rolling on modified endothelial PSGL-1. Arteriosclerosis Thrombosis and Vascular Biology, 27(5), 990-2. https://doi.org/10.1161/ATVBAHA.107.141689

Bernhagen, J., Krohn, R., Lue, H., Gregory, J. L., Zernecke, A., Koenen, R. R., Dewor, M., Georgiev, I., Schober, A., Leng, L., Kooistra, T., Fingerle-Rowson, G., Ghezzi, P., Kleemann, R., McColl, S. R., Bucala, R., Hickey, M. J., & Weber, C. (2007). MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment. Nature Medicine, 13(5), 587-96. https://doi.org/10.1038/nm1567

Meex, S. J., van Greevenbroek, M. M. J., Ayoubi, T. A., Vlietinck, R., van Vliet-Ostaptchouk, J. V., Hofker, M. H., Vermeulen, V. M., Schalkwijk, C. G., Feskens, E. J., Boer, J. M., Stehouwer, C. D., van der Kallen, C. J. H., & de Bruin, T. W. (2007). Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians. Journal of Clinical Endocrinology & Metabolism, 92(7), 2720-2725. https://doi.org/10.1210/jc.2006-2280

op den Buijsch, R. A., van de Plas, A., Stolk, L. M. L., Christiaans, M. H., van Hooff, J. P., Undre, N. A., van Dieijen-Visser, M. P., & Bekers, O. (2007). Evaluation of limited sampling strategies for tacrolimus. European Journal of Clinical Pharmacology, 63(11), 1039-1044. https://doi.org/10.1007/s00228-007-0354-9

Veltkamp, M., Wijnen, P. A. H. M., Moorsel, C. H., Rijkers, G. T., Ruven, H. J., Heron, M., Bekers, O., Claessen, A. M., Drent, M., Van den Bosch, J. M. M., & Grutters, J. C. (2007). Linkage between Toll-like receptor (TLR) 2 promotor and intron polymorphisms: functional effects and relevance to sarcoidosis.Clinical and Experimental Immunology, 149(3), 453-462. https://doi.org/10.1111/j.1365-2249.2007.03428.x

Wijnen, P. A. H. M., Op den Buisch, R., Drent, M., Kuipers, P. M. J. C., Neefs, C., Bast, A., Bekers, O., & Koek, G. H. (2007). Review article: The prevalence and clinical relevance of cytochrome P450 polymorphisms.Alimentary Pharmacology & Therapeutics, 26(2), 211-219. https://doi.org/10.1111/j.1365-2036.2007.03490.x

op den Buijsch, R. A., Christiaans, M. H., Stolk, L. M. L., de Vries, J. E., Cheung, C. Y., Undre, N. A., van Hooff, J. P., van Dieijen-Visser, M. P., & Bekers, O. (2007). Tacrolimus pharmacokinetics and pharmacogenetics: influence of adenosine triphosphate-binding cassette B1 (ABCB1) and cytochrome (CYP) 3A polymorphisms. Fundamental & Clinical Pharmacology, 21(4), 427-435. https://doi.org/10.1111/j.1472-8206.2007.00504.x

Llerena, A., Michel, G., Jeannesson, E., Wong, S., Manolopoulos, V. G., Hockett, R. D., Boubekeur, K., Siest, G., Beaune, P., Haefliger, C., Arnold, H. P., Junien, C., Petrovic, N., Molloy, R., Bekers, O., Donnelly, C., Arens, H. J., Kaput, J., & McComb, J. (2007). Third Santorini conference pharmacogenomics workshop report: "Pharmacogenomics at the crossroads: what else than good science will be needed for the field to become part of Personalized Medicine?". Clinical Chemistry and Laboratory Medicine, 45(7), 843-850. https://doi.org/10.1515/CCLM.2007.182

Prinzen, L., Miserus, R.-J. J. H. M., Dirksen, A., Hackeng, T. M., Deckers, N., Bitsch, N. J., Megens, R. T. A., Douma, K., Heemskerk, J. W., Kooi, M. E., Frederik, P. M., Slaaf, D. W., van Zandvoort, M. A. M. J., & Reutelingsperger, C. P. M. (2007). Optical and magnetic resonance imaging of cell death and platelet activation using annexin A5-functionalized quantum dots. Nano Letters, 7(1), 93-100. https://doi.org/10.1021/nl062226r

Langereis, S., Dirksen, A., Hackeng, T. M., van Genderen, M. H. P., & Meijer, E. W. (2007). Dendrimers and magnetic resonance imaging. New Journal of Chemistry, 31(7), 1152-1160. https://doi.org/10.1039/b616960k

Dirksen, A., Dirksen, S., Hackeng, T. M., & Dawson, P. E. (2006). Nucleophilic catalysis of hydrazone formation and transimination: Implications for dynamic covalent chemistry. Journal of the American Chemical Society, 128(49), 15602-15603. https://doi.org/10.1021/ja067189k