Loeffen, R., Godschalk, T. C., van Oerle, R., Spronk, H. M. H., Hackeng, C. M., ten Berg, J. M., & ten Cate, H. (2015). The hypercoagulable profile of patients with stent thrombosis. Heart, 101(14), 1126-1132. https://doi.org/10.1136/heartjnl-2014-306685

ENGAGE Consortium (2015). Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. Plos Genetics, 11(7), Article e1005230. https://doi.org/10.1371/journal.pgen.1005230

den Exter, P. L., van Es, J., Kroft, L. J. M., Erkens, P. M. G., Douma, R. A., Mos, I. C. M., Jonkers, G., Hovens, M. M. C., Durian, M. F., ten Cate, H., Beenen, L. F. M., Kamphuisen, P. W., & Huisman, M. V. (2015). Thromboembolic resolution assessed by CT pulmonary angiography after treatment for acute pulmonary embolism. Thrombosis and Haemostasis, 114(1), 26-34. https://doi.org/10.1160/TH14-10-0842

Spronk, H. M. H., Braunschweig, T., Rossaint, R., Wuest, D. C., van Oerle, R., Lauritzen, B., Tolba, R., & Grottke, O. (2015). Recombinant Factor VIIa Reduces Bleeding after Blunt Liver Injury in a Pig Model of Dilutional Coagulopathy under Severe Hypothermia. PLOS ONE, 10(6), Article e0113979. https://doi.org/10.1371/journal.pone.0113979

Draisma, H. H. M., Pool, R., Kobl, M., Jansen, R., Petersen, A.-K., Vaarhorst, A. A. M., Yet, I., Haller, T., Demirkan, A., Esko, T., Zhu, G., Böhringer, S., Beekman, M., van Klinken, J. B., Römisch-Margl, W., Prehn, C., Adamski, J., de Craen, A. J. M., van Leeuwen, E. M., ... Boomsma, D. I. (2015). Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. Nature Communications, 6, 7208. https://doi.org/10.1038/ncomms8208

Mastenbroek, T. G., Van Geffen, J. P., Heemskerk, J. W. M., & Cosemans, J. M. E. M. (2015). Acute and persistent platelet and coagulant activities in atherothrombosis. Journal of Thrombosis and Haemostasis, 13, S272-S280. https://doi.org/10.1111/jth.12972

WiN Study Group (2015). CLEC4M and STXBP5 gene variations contribute to von Willebrand factor level variation in von Willebrand disease. Journal of Thrombosis and Haemostasis, 13(6), 956-66. https://doi.org/10.1111/jth.12927

Kuijpers, M. J. E., Mattheij, N. J. A., Cipolla, L., van Geffen, J. P., Lawrence, T., Donners, M. M. P. C., Boon, L., Lievens, D., Torti, M., Noels, H., Gerdes, N., Cosemans, J. M. E. M., Lutgens, E., & Heemskerk, J. W. M. (2015). Platelet CD40L Modulates Thrombus Growth Via Phosphatidylinositol 3-Kinase beta, and Not Via CD40 and I kappa B Kinase alpha. Arteriosclerosis Thrombosis and Vascular Biology, 35(6), 1374-1381. https://doi.org/10.1161/ATVBAHA.114.305127

Swieringa, F., Kuijpers, M. J. E., Lamers, M. M. E., van der Meijden, P. E. J., & Heemskerk, J. W. M. (2015). Rate-limiting roles of the tenase complex of factors VIII and IX in platelet procoagulant activity and formation of platelet-fibrin thrombi under flow. Haematologica-the Hematology Journal, 100(6), 748-756. https://doi.org/10.3324/haematol.2014.116863

Grottke, O., & ten Cate, H. (2015). Reply to Faraoni D, Fenger-Eriksen C, Gillard S et al. Evaluation of dynamic parameters of thrombus formation measured on whole blood using rotational thromboelastometry in children undergoing cardiac surgery: a descriptive study. Pediatric Anesthesia, 25(6), 646-647. https://doi.org/10.1111/pan.12650

Surakka, I., Horikoshi, M., Mägi, R., Sarin, A.-P., Mahajan, A., Lagou, V., Marullo, L., Ferreira, T., Miraglio, B., Timonen, S., Kettunen, J., Pirinen, M., Karjalainen, J., Thorleifsson, G., Hägg, S., Hottenga, J.-J., Isaacs, A., Ladenvall, C., Beekman, M., ... Ripatti, S. (2015). The impact of low-frequency and rare variants on lipid levels. Nature Genetics, 47(6), 589-97. https://doi.org/10.1038/ng.3300

Hu, Q., van Gaal, E. V. B., Brundel, P., Ippel, H., Hackeng, T., Rijcken, C. J. F., Storm, G., Hennink, W. E., & Prakash, J. (2015). A novel approach for the intravenous delivery of leuprolide using core-cross-linked polymeric micelles. Journal of Controlled Release, 205, 98-108. https://doi.org/10.1016/j.jconrel.2014.12.023

Hermanns, M. I., Grossmann, V., Spronk, H. M. H., Schulz, A., Juenger, C., Laubert-Reh, D., Mazur, J., Gori, T., Zeller, T., Pfeiffer, N., Beutel, M., Blankenberg, S., Muenzel, T., Lackner, K. J., Hoek - ten Cate, A. J., ten Cate, H., & Wild, P. S. (2015). Distribution, genetic and cardiovascular determinants of FVIII:c - Data from the population-based Gutenberg Health Study. International Journal of Cardiology, 187, 166-174. https://doi.org/10.1016/j.ijcard.2015.03.330

van den Berg, S. M., Seijkens, T. T. P., Kusters, P. J. H., Zarzycka, B., Beckers, L., den Toom, M., Gijbels, M. J. J., Chatzigeorgiou, A., Weber, C., de Winther, M. P. J., Chavakis, T., Nicolaes, G. A. F., & Lutgens, E. (2015). Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice. International Journal of Obesity, 39(5), 782-790. https://doi.org/10.1038/ijo.2014.198

Geenen, I. L. A., Molin, D. G. M., van den Akker, N. M. S., Jeukens, F., Spronk, H. M., Schurink, G. W. H., & Post, M. J. (2015). Endothelial cells (ECs) for vascular tissue engineering: venous ECs are less thrombogenic than arterial ECs. Journal of Tissue Engineering and Regenerative Medicine, 9(5), 564-576. https://doi.org/10.1002/term.1642

Knapen, M. H. J., Braam, L. A. J. L. M., Drummen, N. E., Bekers, O., Hoeks, A. P. G., & Vermeer, C. (2015). Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women A double-blind randomised clinical trial. Thrombosis and Haemostasis, 113(5), 1135-1144. https://doi.org/10.1160/TH14-08-0675

Nagy, R. A., van Montfoort, A. P. A., Dikkers, A., van Echten-Arends, J., Homminga, I., Land, J. A., Hoek - ten Cate, A., & Tietge, U. J. F. (2015). Presence of bile acids in human follicular fluid and their relation with embryo development in modified natural cycle IVF. Human Reproduction, 30(5), 1102-1109. https://doi.org/10.1093/humrep/dev034

Posthuma, J. J., van der Meijden, P. E. J., ten Cate, H., & Spronk, H. M. H. (2015). Short- and Long-term exercise induced alterations in haemostasis: a review of the literature. Blood Reviews, 29(3), 171-178. https://doi.org/10.1016/j.blre.2014.10.005

Zarzycka, B., Nicolaes, G. A. F., & Lutgens, E. (2015). Targeting the adaptive immune system: new strategies in the treatment of atherosclerosis. Expert Review of Clinical Pharmacology, 8(3), 297-313. https://doi.org/10.1586/17512433.2015.1025052

Whyte, C. S., Swieringa, F., Mastenbroek, T. G., Lionikiene, A. S., Lance, M. D., van der Meijden, P. E. J., Heemskerk, J. W. M., & Mutch, N. J. (2015). Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow. Blood, 125(16), 2568-2578. https://doi.org/10.1182/blood-2014-09-599480

Vries, M. H. M., Wagenaar, A., Verbruggen, S. E. L., Molin, D. G. M., Dijkgraaf, I., Hackeng, T., & Post, M. J. (2015). CXCL1 promotes arteriogenesis through enhanced monocyte recruitment into the peri-collateral space. Angiogenesis, 18(2), 163-171. https://doi.org/10.1007/s10456-014-9454-1

Ippel, H., Miller, M. C., Berbis, M. A., Suylen, D., Andre, S., Hackeng, T. M., Canada, F. J., Weber, C., Gabius, H.-J., Jimenez-Barbero, J., & Mayo, K. H. (2015). H-1, C-13, and N-15 backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3. Biomolecular Nmr Assignments, 9(1), 59-63. https://doi.org/10.1007/s12104-014-9545-3

Plompen, E. P. C., Hansen, B. E., Schouten, J. N. L., Darwish Murad, S., Loth, D. W., Brouwer, W. P., Isaacs, A., Taimr, P., Hofman, A., van Duijn, C. M., Uitterlinden, A. G., Stricker, B. H. C., Leebeek, F. W. G., & Janssen, H. L. A. (2015). Interferon gamma receptor 2 gene variants are associated with liver fibrosis in the general population: the Rotterdam Study. Gut, 64(4), 692-4. https://doi.org/10.1136/gutjnl-2014-308398

Kicken, C., Van Poucke, S., Marcus, A. E., Lance, M. D., & Henskens, Y. (2015). Response of platelet concentrates to pressure and temperature changes without impairment of the in vitro function. Thrombosis Research, 135(4), 679-683. https://doi.org/10.1016/j.thromres.2015.01.004

Strijkers, R. H. W., de Wolf, M. A. F., Arnoldussen, C. W. K. P., Timbergen, M. J. M., de Graaf, R., Hoek - ten Cate, A. J., & Wittens, C. H. A. (2015). Venous In-stent Thrombosis Treated by Ultrasound Accelerated Catheter Directed Thrombolysis. European Journal of Vascular and Endovascular Surgery, 49(4), 440-447. https://doi.org/10.1016/j.ejvs.2015.01.006

Benyamin, B., Esko, T., Ried, J. S., Radhakrishnan, A., Vermeulen, S. H., Traglia, M., Gögele, M., Anderson, D., Broer, L., Podmore, C., Luan, J., Kutalik, Z., Sanna, S., van der Meer, P., Tanaka, T., Wang, F., Westra, H.-J., Franke, L., Mihailov, E., ... Whitfield, J. B. (2015). Correction: Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nature Communications, 6, 6542. https://doi.org/10.1038/ncomms7542

van Leeuwen, E. M., Karssen, L. C., Deelen, J., Isaacs, A., Medina-Gomez, C., Mbarek, H., Kanterakis, A., Trompet, S., Postmus, I., Verweij, N., van Enckevort, D. J., Huffman, J. E., White, C. C., Feitosa, M. F., Bartz, T. M., Manichaikul, A., Joshi, P. K., Peloso, G. M., Deelen, P., ... van Duijn, C. (2015). Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels. Nature Communications, 6, 6065. https://doi.org/10.1038/ncomms7065

van Bussel, B. C. T., Henry, R. M. A., Ferreira, I., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Twisk, J. W. R., Feskens, E. J. M., Schalkwijk, C. G., & Stehouwer, C. D. A. (2015). A Healthy Diet is Associated with Less Endothelial Dysfunction and Less Low-Grade Inflammation over a 7-Year Period in Adults at Risk of Cardiovascular Disease. Journal of Nutrition, 145(3), 532-540. https://doi.org/10.3945/jn.114.201236

Nuzzo, F., Bulato, C., Nielsen, B. I., Lee, K., Wielders, S. J., Simioni, P., Key, N. S., & Castoldi, E. (2015). Characterization of an apparently synonymous F5 mutation causing aberrant splicing and factor V deficiency. Haemophilia, 21(2), 241-248. https://doi.org/10.1111/hae.12554

GARFIELD-AF Investigators, & ten Cate, H. (2015). Does Sex Affect Anticoagulant Use for Stroke Prevention in Nonvalvular Atrial Fibrillation? The Prospective Global Anticoagulant Registry in the FIELD-Atrial Fibrillation. Circulation : Cardiovascular Quality and Outcomes, 8(2), S12-S20. https://doi.org/10.1161/CIRCOUTCOMES.114.001556

van Geffen, J. P., Kleinegris, M.-C., Verdoold, R., Baaten, C. C. F. M. J., Cosemans, J. M. E. M., Clemetson, K. J., ten Cate, H., Roest, M., de Laat, B., & Heemskerk, J. W. M. (2015). Normal Platelet Activation Profile in Patients with Peripheral Arterial Disease on Aspirin. Thrombosis Research, 135(3), 513-520. https://doi.org/10.1016/j.thromres.2014.12.029

Eijgenraam, P., Meertens, N., van den Ham, R., ten Cate, H., & Hoek - ten Cate, A. (2015). The effect of clinical decision support on adherence to thrombosis prophylaxis guidelines in medical patients; A single center experience. Thrombosis Research, 135(3), 464-471. https://doi.org/10.1016/j.thromres.2014.12.012

Dargaud, Y., Scoazec, J. Y., Wielders, S. J. H., Trzeciak, C., Hackeng, T. M., Negrier, C., Hemker, H. C., Lindhout, T., & Castoldi, E. (2015). Characterization of an autosomal dominant bleeding disorder caused by a thrombomodulin mutation. Blood, 125(9), 1497-1501. https://doi.org/10.1182/blood-2014-10-604553

van Bussel, F. C. G., van Bussel, B. C. T., Hoeks, A. P. G., op 't Roodt, J., Henry, R. M. A., Ferreira, I., Vanmolkot, F. H. M., Schalkwijk, C. G., Stehouwer, C. D. A., & Reesink, K. D. (2015). A Control Systems Approach to Quantify Wall Shear Stress Normalization by Flow-Mediated Dilation in the Brachial Artery. PLOS ONE, 10(2), Article e0115977. https://doi.org/10.1371/journal.pone.0115977

Musumeci, L., Kuijpers, M. J., Gilio, K., Hego, A., Theatre, E., Maurissen, L., Vandereyken, M., Diogo, C. V., Lecut, C., Guilmain, W., Bobkova, E. V., Eble, J. A., Dahl, R., Drion, P., Rascon, J., Mostofi, Y., Yuan, H., Sergienko, E., Chung, T. D. Y., ... Rahmouni, S. (2015). Dual-Specificity Phosphatase 3 Deficiency or Inhibition Limits Platelet Activation and Arterial Thrombosis. Circulation, 131(7), 656-U194. https://doi.org/10.1161/CIRCULATIONAHA.114.010186

Karshovska, E., Zhao, Z., Blanchet, X., Schmitt, M. M. N., Bidzhekov, K., Soehnlein, O., von Hundelshausen, P., Mattheij, N. J., Cosemans, J. M. E. M., Megens, R. T. A., Koeppel, T. A., Schober, A., Hackeng, T. M., Weber, C., & Koenen, R. R. (2015). Hyperreactivity of Junctional Adhesion Molecule A-Deficient Platelets Accelerates Atherosclerosis in Hyperlipidemic Mice. Circulation Research, 116(4), 587-599. https://doi.org/10.1161/CIRCRESAHA.116.304035

Locke, A. E., Kahali, B., Berndt, S. I., Justice, A. E., Pers, T. H., Day, F. R., Powell, C., Vedantam, S., Buchkovich, M. L., Yang, J., Croteau-Chonka, D. C., Esko, T., Fall, T., Ferreira, T., Gustafsson, S., Kutalik, Z., Luan, J., Mägi, R., Randall, J. C., ... Speliotes, E. K. (2015). Genetic studies of body mass index yield new insights for obesity biology. Nature, 518(7538), 197-206. https://doi.org/10.1038/nature14177

Shungin, D., Winkler, T. W., Croteau-Chonka, D. C., Ferreira, T., Locke, A. E., Mägi, R., Strawbridge, R. J., Pers, T. H., Fischer, K., Justice, A. E., Workalemahu, T., Wu, J. M. W., Buchkovich, M. L., Heard-Costa, N. L., Roman, T. S., Drong, A. W., Song, C., Gustafsson, S., Day, F. R., ... Mohlke, K. L. (2015). New genetic loci link adipose and insulin biology to body fat distribution. Nature, 518(7538), 187-196. https://doi.org/10.1038/nature14132

Zarzycka, B., Seijkens, T., Nabuurs, S. B., Ritschel, T., Grommes, J., Soehnlein, O., Schrijver, R., van Tiel, C. M., Hackeng, T. M., Weber, C., Giehler, F., Kieser, A., Lutgens, E., Vriend, G., & Nicolaes, G. A. F. (2015). Discovery of Small Molecule CD40-TRAF6 Inhibitors. Journal of Chemical Information and Modeling, 55(2), 294-307. https://doi.org/10.1021/ci500631e

Jainandunsing, S., Özcan, B., Rietveld, T., van Miert, J. N. I., Isaacs, A. J., Langendonk, J. G., de Rooij, F. W. M., & Sijbrands, E. J. G. (2015). Failing beta-cell adaptation in South Asian families with a high risk of type 2 diabetes. Acta Diabetologica, 52(1), 11-9. https://doi.org/10.1007/s00592-014-0588-9

Du, J., Wichapong, K., Hackeng, T. M., & Nicolaes, G. A. F. (2015). Molecular simulation studies of human coagulation factor VIII C domain-mediated membrane binding. Thrombosis and Haemostasis, 113(2), 373-384. https://doi.org/10.1160/TH14-02-0180

Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M.-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., ... EPIC-InterAct Consortium (2015). Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nature Communications, 6, 5897. https://doi.org/10.1038/ncomms6897

Hendrikx, G., De Saint-Hubert, M., Dijkgraaf, I., Bauwens, M., Douma, K., Wierts, R., Pooters, I., van den Akker, N. M., Hackeng, T. M., Post, M. J., & Mottaghy, F. M. (2015). Molecular imaging of angiogenesis after myocardial infarction by (111)In-DTPA-cNGR and (99m)Tc-sestamibi dual-isotope myocardial SPECT. EJNMMI Research, 5, 13-22. Article 2. https://doi.org/10.1186/s13550-015-0081-7

Prochaska, J. H., Goebel, S., Keller, K., Coldewey, M., Ullmann, A., Lamparter, H., Juenger, C., Al-Bayati, Z., Baer, C., Walter, U., Bickel, C., ten Cate, H., Muenzel, T., & Wild, P. S. (2015). Quality of oral anticoagulation with phenprocoumon in regular medical care and its potential for improvement in a telemedicine-based coagulation service - results from the prospective, multi-center, observational cohort study thrombEVAL. BMC Medicine, 13, Article 14. https://doi.org/10.1186/s12916-015-0268-9

Bensdorp, A. J., Tjon-Kon-Fat, R. I., Bossuyt, P. M. M., Koks, C. A. M., Oosterhuis, G. J. E., Hoek - ten Cate, A., Hompes, P. G. A., Broekmans, F. J. M., Verhoeve, H. R., de Bruin, J. P., van Golde, R., Repping, S., Cohlen, B. J., Lambers, M. D. A., van Bommel, P. F., Slappendel, E., Perquin, D., Smeenk, J. M., Pelinck, M. J., ... van Wely, M. (2015). Prevention of multiple pregnancies in couples with unexplained or mild male subfertility: randomised controlled trial of in vitro fertilisation with single embryo transfer or in vitro fertilisation in modified natural cycle compared with intrauterine insemination with controlled ovarian hyperstimulation. BMJ, 350, Article g7771. https://doi.org/10.1136/bmj.g7771

Cardinaels, E. P. M., Daamen, M. A. M. J., Bekers, O., ten Kate, J., Niens, M., van Suijlen, J. D. E., van Dieijen-Visser, M. P., Brunner-La Rocca, H. P., Schols, J. M. G. A., & Mingels, A. M. A. (2015). Clinical Interpretation of Elevated Concentrations of Cardiac Troponin T, but Not Troponin I, in Nursing Home Residents. Journal of the American Medical Directors Association, 16(10), 884-891. https://doi.org/10.1016/j.jamda.2015.06.026

Bouman, A. C., ten Cate-Hoek, A. J., Ramaekers, B. L. T., & Joore, M. A. (2015). Sample Size Estimation for Non-Inferiority Trials: Frequentist Approach versus Decision Theory Approach. PLOS ONE, 10(6), Article e0130531. https://doi.org/10.1371/journal.pone.0130531

Hendriksen, J. M. T., Geersing, G. J., van Voorthuizen, S. C., Oudega, R., ten Cate-Hoek, A. J., Joore, M. A., Moons, K. G. M., & Koffijberg, H. (2015). The cost-effectiveness of point-of-care D-dimer tests compared with a laboratory test to rule out deep venous thrombosis in primary care. Expert Review of Molecular Diagnostics, 15(1), 125-136. https://doi.org/10.1586/14737159.2015.976202

Nuzzo, F., Paraboschi, E. M., Straniero, L., Pavlova, A., Duga, S., & Castoldi, E. (2015). Identification of a novel large deletion in a patient with severe factor V deficiency using an in-house F5 MLPA assay. Haemophilia, 21(1), 140-147. https://doi.org/10.1111/hae.12536