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Catheter treatment is not only effective, but also cost-effective for ischemic stroke

Catheter treatment is not only effective, but also cost-effective for ischemic stroke

29 September 2026

With ischemic stroke, every minute counts. However, many patients do not seek hospital care until it is too late, for example, because symptoms are not immediately recognized or because people wake up with signs of neurological deficits. As a result, a group of patients is no longer eligible for catheter treatment. 

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Platelets: more than a band-aid

Platelets: more than a band-aid

23 September 2026

Some processes in our body might seem obvious to us. If you cut your finger, the bleeding will stop shortly and form a scab. Behind that seemingly simple process hides a sophisticated system of platelets and clotting factors. By now, we know that platelets do much more than halt bleeding: they function as information carriers and regulators of disease processes. 

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Carim Maastricht
Carim Maastricht

Thijs van Herpt

Post doc

Dr Thijs van Herpt is an internist-intensivist at Maastricht UMC+. He trained in internal medicine at Erasmus MC in Rotterdam and obtained his PhD on type 2 diabetes mellitus and metabolic syndrome.

His research focusses on cardiovascular critical care and metabolic monitoring in critically ill patients. He is particularly interested in dysglycaemia, sodium and fluid balance, and metabolic disturbances as markers of physiology, organ dysfunction and response to treatment. Rather than studying these abnormalities in isolation, his work aims to understand what they reveal about the changing physiology of the critically ill patient.

As a member of the Shock and Mechanical Support Team, he has a particular interest in severe circulatory failure, cardiac surgery and mechanical circulatory support. A central theme is the interaction between haemodynamics and metabolism, and how bedside monitoring can help translate complex physiological changes into clinically meaningful information.

Pharmacology and toxicology form an important complementary research line. In close collaboration with the Department of Clinical Pharmacy and Toxicology, he works on questions related to therapeutic drug monitoring, altered pharmacokinetics during critical illness, drug exposure, toxicity and treatment response.

He is also involved in the HumanICare programme, studying outcomes beyond ICU survival, including pre-admission health, recovery, functioning and quality of life. His research is deliberately embedded in daily ICU practice and strongly multidisciplinary. ICU nurses play an important role in this approach, combining continuous bedside observation with detailed knowledge of changes in physiology and treatment response.

His ambition is to develop pragmatic, clinically embedded research in which cardiovascular physiology, metabolism, pharmacology and bedside observation come together. The aim is to better understand the critically ill patient and to translate that understanding into more precise and meaningfu

Thijs van herpt 64afff8e1ea38

Department of Intensive Care
P. Debyelaan 25
6229 HX, Maastricht
T: +31(0)43 387 13 20 

  • 2026
    • Schellens, J., Nagy, M., Hulshof, A. M., van Rosmalen, F., van Oerle, R., van Herpt, T. T. W., Alnima, T., Mulder, M. M. G., Hellenbrand, D., ten Cate, H., Driessen, R. G. H., Sels, J. W. E. M., van der Horst, I. C. C., Henskens, Y. M. C., van Bussel, B. C. T., Spronk, H. M. H., & Dutch Covid and Thrombosis Coalition (2026). Inhibition of inflammation reduces hypofibrinolysis in severe COVID-19: A nested case-control study within the MaastrICCht cohort. Thrombosis Research, 262, Article 109723. https://doi.org/10.1016/j.thromres.2026.109723
    • Baldussu, E., Brandts, L., Pennetta, F., van Rosmalen, F., Schalkx, H. J., Smulders, M. W., van der Horst, I. C. C., Wildberger, J. E., van Herpt, T. T. W., Mihl, C., van Bussel, B. C. T., Martens, B., & Driessen, R. G. H. (2026). Coronary artery calcification is associated with reduced survival in mechanically ventilated COVID-19 patients in the MaastrICCht cohort. Scientific Reports, 16(1), Article 10013. https://doi.org/10.1038/s41598-026-40733-x
  • 2024
    • de Kok, J. W. T. M., van Bussel, B. C. T., Schnabel, R., van Herpt, T. T. W., Driessen, R. G. H., Meijs, D. A. M., Goossens, J. A., Mertens, H. J. M. M., van Kuijk, S. M. J., Wynants, L., van der Horst, I. C. C., & van Rosmalen, F. (2024). Corrigendum to Table 0; documenting the steps to go from clinical database to research dataset Journal of Clinical Epidemiology Volume 170 (2024) 111342. Journal of Clinical Epidemiology, 172, Article 111436. https://doi.org/10.1016/j.jclinepi.2024.111436
    • de Kok, J. W. T. M., van Bussel, B. C. T., Schnabel, R., van Herpt, T. T. W., Driessen, R. G. H., Meijs, D. A. M., Goossens, J. A., Mertens, H. J. M. M., van Kuijk, S. M. J., Wynants, L., van der Horst, I. C. C., & van Rosmalen, F. (2024). Table 0; documenting the steps to go from clinical database to research dataset. Journal of Clinical Epidemiology, 170, Article 111342. https://doi.org/10.1016/j.jclinepi.2024.111342
    • Aydeniz, E., Weberndorfer, V., Brandts, L., Smulders, M. W., van Herpt, T. T. W., Martens, B., Vernooy, K., Linz, D., van der Horst, I. C. C., Wildberger, J. E., van Bussel, B. C. T., Driessen, R. G. H., & Mihl, C. (2024). Pericardial Fat Is Associated With Less Severe Multiorgan Failure Over Time in Patients With Coronavirus Disease-19: The Maastricht Intensive Care COVID Cohort. Journal of Thoracic Imaging, 39(3), W32-W39. https://doi.org/10.1097/RTI.0000000000000732
    • de Kok, J. W. T. M., van Rosmalen, F., Koeze, J., Keus, F., van Kuijk, S. M. J., Castela Forte, J., Schnabel, R. M., Driessen, R. G. H., van Herpt, T. T. W., Sels, J.-W. E. M., Bergmans, D. C. J. J., Lexis, C. P. H., van Doorn, W. P. T. M., Meex, S. J. R., Xu, M., Borrat, X., Cavill, R., van der Horst, I. C. C., & van Bussel, B. C. T. (2024). Deep embedded clustering generalisability and adaptation for integrating mixed datatypes: two critical care cohorts. Scientific Reports, 14(1), Article 1045. https://doi.org/10.1038/s41598-024-51699-z
  • 2023
    • van Herpt, T. T. W., van Rosmalen, F., Hulsewé, H. P. M. G., van der Horst-Schrivers, A. N. A., Driessen, M., Jetten, R., Zelis, N., de Galan, B. E., van Kuijk, S. M. J., van der Horst, I. C. C., & van Bussel, B. C. T. (2023). Hyperglycemia and glucose variability are associated with worse survival in mechanically ventilated COVID-19 patients: the prospective Maastricht Intensive Care Covid Cohort. Diabetology & Metabolic Syndrome, 15(1), Article 253. https://doi.org/10.1186/s13098-023-01228-1
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