Arina ten Cate-Hoek

Associate professor

Dr Arina ten Cate-Hoek graduated as a medical doctor at the University of Amsterdam and as a Clinical Epidemiologist at the University of Maastricht. Her PhD thesis was on new developments in diagnosis and treatment of deep venous thrombosis. She currently holds a clinical position at the Heart+Vascular Center of Maastricht UMC+ and her specialty is in the prevention and treatment of venous thrombotic disease, especially the Post Thrombotic Syndrome. She is the medical director of the Anticoagulation Clinic as well as the medical coordinator of the Thrombosis Expertise Centre Maastricht. She gained some laboratory experience in the laboratory of the Harvard University Beth Israel Deaconess Medical Center in Boston and the Laboratory of the Netherlands Red Cross Blood Transfusion Service (CLB)in Amsterdam.

Since 2003, she has been working at the Maastricht UMC+ where she combines clinical work with clinical and translational research. The main topic of het research is prevention and treatment of the Post Thrombotic Syndrome. She received research grants mainly from ZonMw Efficiency research.

Department of Internal Medicine
P. Debyelaan 25, 6229 HX Maastricht
PO Box 612, 6200 MD Maastricht

2020
- Notten, P., Arnoldussen, C. W. K. P., Brans, R., de Smet, A. A. E. A., Tick, L. W., van de Poel, M. H. W., Wikkeling, O. R. M., Vleming, L.-J., Koster, A., Jie, K.-S. G., Jacobs, E. M. G., Ebben, H. P., Planken, N., ten Cate, H., Wittens, C. H. A., & ten Cate-Hoek, A. J. (2020). Association of Successful Ultrasound-Accelerated Catheter-Directed Thrombolysis with Postthrombotic Syndrome: A Post Hoc Analysis of the CAVA Trial. Thrombosis and Haemostasis, 120(08), 1188-1199. https://doi.org/10.1055/s-0040-1713171
- Brouns, S. H., Bruggemann, R., Linkens, A. E. M. J. H., Magdelijns, F. J., Joosten, H., Heijnen, R., ten Cate-Hoek, A. J., Schols, J. M. G. A., ten Cate, H., & Spaetgens, B. (2020). Mortality and the Use of Antithrombotic Therapies Among Nursing Home Residents withCOVID-19. Journal of the American Geriatrics Society, 68(8), 1647-1652. https://doi.org/10.1111/jgs.16664
- van Miert, J. H. A., Veeger, N. J. G. M., ten Cate-Hoek, A. J., Piersma-Wichers, M., & Meijer, K. (2020). Effect of switching from acenocoumarol to phenprocoumon on time in therapeutic range and INR variability: A cohort study. PLOS ONE, 15(7), Article 0235639. https://doi.org/10.1371/journal.pone.0235639
- Leader, A., ten Cate, V., ten Cate-Hoek, A. J., Beckers, E. A. M., Spectre, G., Giaccherini, C., Gurevich-Shapiro, A., Krashin, E., Raanani, P., Schouten, H. C., Falanga, A., & ten Cate, H. (2020). Anticoagulation in thrombocytopenic patients with hematological malignancy: A multinational clinical vignette-based experiment. European journal of internal medicine, 77, 86-96. https://doi.org/10.1016/j.ejim.2020.03.005
- Ordieres-Ortega, L., Demelo-Rodriguez, P., Galeano-Valle, F., Kremers, B. M. M., ten Cate-Hoek, A. J., & ten Cate, H. (2020). Predictive value of D-dimer testing for the diagnosis of venous thrombosis in unusual locations: A systematic review. Thrombosis Research, 189, 5-12. https://doi.org/10.1016/j.thromres.2020.02.009
- Notten, P., van Laanen, J. H. H., Eijgenraam, P., de Wolf, M. A. F., Kurstjens, R. L. M., ten Cate, H., & ten Cate-Hoek, A. J. (2020). Quality of anticoagulant therapy and the incidence of in-stent thrombosis after venous stenting. Research and practice in thrombosis and haemostasis, 4(4), 594-603. https://doi.org/10.1002/rth2.12330
- d'Alessandro, E., Becker, C., Bergmeier, W., Bode, C., Bourne, J. H., Brown, H., Buller, H. R., ten Cate-Hoek, A. J., ten Cate, V., van Cauteren, Y. J. M., Cheung, Y. F. H., Cleuren, A., Coenen, D., Crijns, H. J. G. M., de Simone, I., Dolleman, S. C., Klein, C. E., Fernandez, D. I., Granneman, L., ... Scientific Reviewer Committee (2020). Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis. Thrombosis and Haemostasis, 120(4), 538-564. https://doi.org/10.1055/s-0040-1708035
- Notten, P., & ten Cate-Hoek, A. J. (2020). Catheter interventions: an unresolved clinical controversy: Authors' reply. The Lancet Haematology, 7(3), e190. https://doi.org/10.1016/s2352-3026(20)30032-6
- Notten, P., ten Cate-Hoek, A. J., Arnoldussen, C. W. K. P., Strijkers, R. H. W., de Smet, A. A. E. A., Tick, L. W., van de Poel, M. H. W., Wikkeling, O. R. M., Vleming, L.-J., Koster, A., Jie, K.-S. G., Jacobs, E. M. G., Ebben, H. P., Coppens, M., Toonder, I., ten Cate, H., & Wittens, C. H. A. (2020). Ultrasound-accelerated catheter-directed thrombolysis versus anticoagulation for the prevention of post-thrombotic syndrome (CAVA): a single-blind, multicentre, randomised trial. The Lancet Haematology, 7(1), E40-E49. https://doi.org/10.1016/S2352-3026(19)30209-1
2019
- Petersohn, S., Ramaekers, B. L. T., Olie, R. H., ten Cate-Hoek, A. J., Daemen, J.-W. H. C., ten Cate, H., & Joore, M. A. (2019). Comparison of three generic quality-of-life metrics in peripheral arterial disease patients undergoing conservative and invasive treatments. Quality of Life Research, 28(8), 2257-2279. https://doi.org/10.1007/s11136-019-02166-0
- Stolk, L. M., de Vries, F., Ebbelaar, C., de Boer, A., Schalekamp, T., Souverein, P., Hoek - ten Cate, A., & Burden, A. (2019). Risk of myocardial infarction in patients with atrial fibrillation using vitamin K antagonists, aspirin or direct acting oral anticoagulants (vol 83, pg 1835, 2017) - correction. British Journal of Clinical Pharmacology, 85(8), 1864-1864. https://doi.org/10.1111/bcp.14001
- Gulpen, A. J. W., ten Cate, H., Henskens, Y. M. C., van Oerle, R., Wetzels, R., Schalla, S., Crijns, H. J., & ten Cate-Hoek, A. J. (2019). The daily practice of direct oral anticoagulant use in patients with atrial fibrillation; an observational cohort study. PLOS ONE, 14(6), Article 0217302. https://doi.org/10.1371/journal.pone.0217302
- Kremers, B. M. M., Birocchi, S., van Oerle, R., Zeerleder, S., Spronk, H. M. H., Mees, B. M. E., Luken, B. M., ten Cate, H., & ten Cate-Hoek, A. J. (2019). Searching for a Common Thrombo-Inflammatory Basis in Patients With Deep Vein Thrombosis or Peripheral Artery Disease. Frontiers in Cardiovascular Medicine, 6, 1-11. Article 33. https://doi.org/10.3389/fcvm.2019.00033
- Leader, A., Ten Cate, V., Ten Cate-Hoek, A. J., Spectre, G., Beckers, E. A. M., Raanani, P., Giaccherini, C., Pereg, D., Schouten, H. C., Falanga, A., & Ten Cate, H. (2019). Managing Anti-Platelet Therapy in Thrombocytopaenic Patients with Haematological Malignancy: A Multinational Clinical Vignette-Based Experiment. Thrombosis and Haemostasis, 119(1), 163-174. https://doi.org/10.1055/s-0038-1676520
2018
- Amin, E. E., Bistervels, I. M., Meijer, K., Tick, L. W., Middeldorp, S., Mostard, G., van de Poel, M., Serne, E. H., Otten, H. M., Klappe, E. M., Joore, M. A., ten Cate, H., ten Wolde, M., & ten Cate-Hoek, A. J. (2018). Reduced incidence of vein occlusion and postthrombotic syndrome after immediate compression for deep vein thrombosis. Blood, 132(21), 2298-2304. https://doi.org/10.1182/blood-2018-03-836783
- Amin, E. E., ten Cate-Hoek, A. J., Bouman, A. C., Meijer, K., Tick, L., Middeldorp, S., Mostard, G., ten Wolde, M., van den Heiligenberg, S., van Wissen, S., van de Poet, M., Villalta, S., Serne, E., Otten, H. M., Klappe, E., Prandoni, P., Prins, M. H., ten Cate, H., & Joore, M. A. (2018). Individually shortened duration versus standard duration of elastic compression therapy for prevention of post-thrombotic syndrome: a cost-effectiveness analysis. The Lancet Haematology, 5(11), E512-E519. https://doi.org/10.1016/S2352-3026(18)30151-0
- Pernot, C. C. E. G., Zwiers, I., ten Cate-Hoek, A. J., & Wittens, C. H. A. (2018). The need for a timely diagnostic workup for patients with venous leg ulcers. Journal of Wound Care, 27(11), 758-763. https://doi.org/10.12968/jowc.2018.27.11.758
- Zwaveling, S., Bloemen, S., de Laat, B., Ten Cate, H., & Ten Cate-Hoek, A. (2018). Calibrated Automated Thrombinography (CAT), a Tool to Identify Patients at Risk of Bleeding during Anticoagulant Therapy: A Systematic Review. TH open : companion journal to thrombosis and haemostasis, 2(3), 291-302. https://doi.org/10.1055/s-0038-1672183
- Amin, E. E., Joore, M. A., ten Cate, H., Meijer, K., Tick, L. W., Middeldorp, S., Mostard, G. J. M., ten Wolde, M., Van den Heiligenberg, S. M., Van Wissen, S., Van de Poel, M. H. W., Villalta, S., Serne, E. H., Otten, H.-M., Klappe, E. H., Prandoni, P., & ten Cate-Hoek, A. J. (2018). Clinical and economic impact of compression in the acute phase of deep vein thrombosis. Journal of Thrombosis and Haemostasis, 16(8), 1555-1563. https://doi.org/10.1111/jth.14163
- Amin, E. E., van Kuijk, S. M. J., Joore, M. A., Prandoni, P., ten Cate, H., & ten Cate-Hoek, A. J. (2018). Development and Validation of a Practical Two-Step Prediction Model and Clinical Risk Score for Post-Thrombotic Syndrome. Thrombosis and Haemostasis, 118(7), 1242-1249. https://doi.org/10.1055/s-0038-1655743
- Vaidya, A., Kleinegris, M.-C., Severens, J. L., Ramaekers, B. L., ten Cate-Hoek, A. J., ten Cate, H., & Joore, M. A. (2018). Comparison of EQ-5D and SF-36 in untreated patients with symptoms of intermittent claudication. Journal of Comparative Effectiveness Research, 7(6), 535-548. https://doi.org/10.2217/cer-2017-0029
- ten Cate, H., Olie, R. H., ten Cate-Hoek, A. J., & Henskens, Y. M. C. (2018). Direct oral anticoagulants: When to consider laboratory testing?International Journal of Laboratory Hematology, 40(S1), 30-33. https://doi.org/10.1111/ijlh.12816
- ten Cate-Hoek, N. J. (2018). Prevention and treatment of the post-thrombotic syndrome. Research and practice in thrombosis and haemostasis, 2(2), 209-219. https://doi.org/10.1002/rth2.12085
- Nagler, M., ten Cate, H., Prins, M. H., & ten Cate-Hoek, A. J. (2018). Risk factors for recurrence in deep vein thrombosis patients following a tailored anticoagulant treatment incorporating residual vein obstruction. Research and practice in thrombosis and haemostasis, 2(2), 299-309. https://doi.org/10.1002/rth2.12079
- Spronk, H. M. H., Padro, T., Siland, J. E., Prochaska, J. H., Winters, J., van der Wal, A. C., Posthuma, J. J., Lowe, G., d'Alessandro, E., Wenzel, P., Coenen, D. M., Reitsma, P. H., Ruf, W., van Gorp, R. H., Koenen, R. R., Vajen, T., Alshaikh, N. A., Wolberg, A. S., Macrae, F. L., ... ten Cate, H. (2018). Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis. Thrombosis and Haemostasis, 118(2), 229-250. https://doi.org/10.1160/TH17-07-0492
- Henskens, Y. M. C., Gulpen, A. J. W., van Oerle, R., Wetzels, R., Verhezen, P., Spronk, H., Schalla, S., Crijns, H. J., ten Cate, H., & ten Cate-Hoek, A. (2018). Detecting clinically relevant rivaroxaban or dabigatran levels by routine coagulation tests or thromboelastography in a cohort of patients with atrial fibrillation. Thrombosis Journal, 16(1), Article 3. https://doi.org/10.1186/s12959-017-0160-2
- Ten Cate, H., Olie, R. H., Ten Cate-Hoek, A. J., & Henskens, Y. M. C. (2018). Direkte orale Antikoagulanzien: Wann sollte ein Labortest erwogen werden?Vasomed, 30(5), 248-249.
- ten Cate-Hoek, A. J., Amin, E. E., Bouman, A. C., Meijer, K., Tick, L. W., Middeldorp, S., Mostard, G. J. M., ten Wolde, M., van den Heiligenberg, S. M., van Wissen, S., van de Poel, M. H. W., Villalta, S., Serne, E. H., Otten, H.-M., Klappe, E. H., Bistervels, I. M., Lauw, M. N., Piersma-Wichers, M., Prandoni, P., ... IDEAL DVT Investigators (2018). Individualised versus standard duration of elastic compression therapy for prevention of post-thrombotic syndrome (IDEAL DVT): a multicentre, randomised, single-blind, allocation-concealed, non-inferiority trial. The Lancet Haematology, 5(1), 25-33. https://doi.org/10.1016/S2352-3026(17)30227-2
- Cate-Hoek, A. T. (2018). Kompression bei tiefer Venenthombose: nur bei Beschwerden. Vasomed, 30(1), 19-20.
2017
- Stolk, L. M., de Vries, F., Ebbelaar, C., de Boer, A., Schalekamp, T., Souverein, P., ten Cate-Hoek, A., & Burden, A. M. (2017). Risk of myocardial infarction in patients with atrial fibrillation using vitamin K antagonists, aspirin or direct acting oral anticoagulants. British Journal of Clinical Pharmacology, 83(8), 1835-1843. https://doi.org/10.1111/bcp.13264
- Bloemen, S., Zwaveling, S., ten Cate, H., ten Cate-Hoek, A., & de Laat, B. (2017). Prediction of bleeding risk in patients taking vitamin K antagonists using thrombin generation testing. PLOS ONE, 12(5), Article e0176967. https://doi.org/10.1371/journal.pone.0176967
- Kleinegris, M.-C. F., Konings, J., Daemen, J. W., Henskens, Y., de Laat, B., Spronk, H. M. H., ten Cate-Hoek, A. J., & ten Cate, H. (2017). Increased Clot Formation in the Absence of Increased Thrombin Generation in Patients with Peripheral Arterial Disease: A Case-Control Study. Frontiers in Cardiovascular Medicine, 4, Article 23. https://doi.org/10.3389/fcvm.2017.00023
- Vries, M. J. A., Bouman, H. J., Olie, R. H., Veenstra, L. F., Zwaveling, S., Verhezen, P. W. M., ten Cate-Hoek, A. J., ten Cate, H., Henskens, Y. M. C., & van der Meijden, P. E. J. (2017). Determinants of agreement between proposed therapeutic windows of platelet function tests in vulnerable patients. European Heart Journal-Cardiovascular Pharmacotherapy, 3(1), 11-17. https://doi.org/10.1093/ehjcvp/pvw026
2016
- Boersma, R. S., Hamulyak, K., van Oerle, R., Tuinenburg, A., Ten Cate - Hoek, A., & Schouten, H. C. (2016). Biomarkers for Prediction of Central Venous Catheter Related-Thrombosis in Patients With Hematological Malignancies. Clinical and Applied Thrombosis-Hemostasis, 22(8), 779-784. https://doi.org/10.1177/1076029615579098
- Cheung, Y. W., Middeldorp, S., Prins, M. H., Pap, A. F., Lensing, A. W. A., Hoek - ten Cate, A., Villalta, S., Milan, M., Beyer-Westendorf, J., Verhamme, P., Bauersachs, R. M., & Prandoni, P. (2016). Post-thrombotic syndrome in patients treated with rivaroxaban or enoxaparin/vitamin K antagonists for acute deep-vein thrombosis A post-hoc analysis. Thrombosis and Haemostasis, 116(4), 733-738. https://doi.org/10.1160/TH16-01-0041
- Hoek - ten Cate, A. (2016). Stockings to prevent post-thrombotic syndrome. BMJ, 353, Article i2897. https://doi.org/10.1136/bmj.i2897
- Eijgenraam, P., ten Cate, H., Henskens, Y., van den Ham, R., & ten Cate - Hoek , A. (2016). Effects of peri-operative bridging with low molecular weight heparins on coagulation during interruption of vitamin K antagonists: A mechanistic study. Thrombosis Research, 140, 59-65. https://doi.org/10.1016/j.thromres.2016.02.019
- Cheung, Y. W., Bouman, A. C., Castoldi, E., Wielders, S. J., Spronk, H. M. H., ten Cate, H., Hoek - ten Cate, A., & ten Wolde, M. (2016). Toll-like receptor 9 gene expression in the post-thrombotic syndrome, residual thrombosis and recurrent deep venous thrombosis: A case-control study. Thrombosis Research, 140, 106-109. https://doi.org/10.1016/j.thromres.2016.02.025
- Amin, E., Joore, M. A., & Hoek - ten Cate, A. (2016). Compression to prevent PTS: a controversy?Phlebology: The Journal of Venous Disease, 31(1 suppl), 41-47. https://doi.org/10.1177/0268355516632986
- Bouman, A. C., Ten Cate - Hoek, A., Dirksen, C. D., & Joore, M. A. (2016). Eliciting patients' preferences for elastic compression stocking therapy in patients after deep vein thrombosis: a potential for improving compliance. Journal of Thrombosis and Haemostasis, 14(3), 510–517. https://doi.org/10.1111/jth.13228
- Tten Cate - Hoek, A., Henke, P. K., & Wakefield, T. W. (2016). The post thrombotic syndrome: Ignore it and it will come back to bite you. Blood Reviews, 30(2), 131-137. https://doi.org/10.1016/j.blre.2015.09.002
- Nagler, M., Bachmann, L. M., ten Cate, H., & ten Cate - Hoek, A. (2016). Diagnostic value of immunoassays for heparin-induced thrombocytopenia: a systematic review and meta-analysis. Blood, 127(5), 546-557. https://doi.org/10.1182/blood-2015-07-661215
- Bouman, A. C., McPherson, H., Cheung, Y. W., ten Wolde, M., ten Cate, H., Ariëns, R., & Ten Cate - Hoek, A. (2016). Clot structure and fibrinolytic potential in patients with post thrombotic syndrome. Thrombosis Research, 137, 85-91. https://doi.org/10.1016/j.thromres.2015.11.013
- Vries, M. J. A., van der Meijden, P. E. J., Henskens, Y. M. C., Ten Cate - Hoek, A., & ten Cate, H. (2016). Assessment of bleeding risk in patients with coronary artery disease on dual antiplatelet therapy A systematic review. Thrombosis and Haemostasis, 115(1), 7-24. https://doi.org/10.1160/TH15-04-0355
- Hoek - ten Cate, A. (2016). Efficacy of compression for the prevention of post-thrombotic syndrome: an unsolved clinical conundrum: Comment on Burgstaller et al, 141-147. Vasa-European Journal of Vascular Medicine, 45(2), 85-86. https://doi.org/10.1024/0301-1526/a000502
- Gulpen, A. J. W., Hoek - ten Cate, A., & Ten Cate, H. (2016). Upstream versus downstream thrombin inhibition. Expert review of cardiovascular therapy, 14(11), 1273-1282. https://doi.org/10.1080/14779072.2016.1224179
2015
- Tjon-Kon-Fat, R. I., Bensdorp, A. J., Bossuyt, P. M. M., Koks, C., Oosterhuis, G. J. E., Hoek - ten Cate, A., Hompes, P., Broekmans, F. J., Verhoeve, H. R., de Bruin, J. P., van Golde, R., Repping, S., Cohlen, B. J., Lambers, M. D. A., van Bommel, P. F., Slappendel, E., Perquin, D., Smeenk, J., Pelinck, M. J., ... van Wely, M. (2015). Is IVF-served two different ways-more cost-effective than IUI with controlled ovarian hyperstimulation?Human Reproduction, 30(10), 2331-2339. https://doi.org/10.1093/humrep/dev193
- Vissenberg, R., van Dijk, M. M., Fliers, E., van der Post, J. A. M., van Wely, M., Bloemenkamp, K. W. M., Hoek - ten Cate, A., Kuchenbecker, W. K., Verhoeve, H. R., Scheepers, H. C. J., Rombout-de Weerd, S., Koks, C., Zwart, J. J., Broekmans, F., Verpoest, W., Christiansen, O. B., Post, M., Papatsonis, D. N. M., Verberg, M. F. G., ... Goddijn, M. (2015). Effect of levothyroxine on live birth rate in euthyroid women with recurrent miscarriage and TPO antibodies (T4-LIFE study). Contemporary Clinical Trials, 44, 134-138. https://doi.org/10.1016/j.cct.2015.08.005
- Hoek - ten Cate, A. J., ten Cate, H., Henskens, Y., van der Meijden, P. E. J., Spronk, H. M. H., & Wittens, C. (2015). Maastricht Consensus Conference on Thrombosis (MCCT): A roadmap for future research, February 11-13, 2015, Maastricht, The Netherlands. Thrombosis Research, 136, S1-S2. https://doi.org/10.1016/j.thromres.2015.07.033
- ten Cate-Hoek, A. J., Weitz, J. I., Gailani, D., Meijer, K., Philippou, H., Bouman, A. C., Whitney Cheung, Y., van Mens, T. E., Govers-Riemslag, J. W., Vries, M., Bleker, S., Biedermann, J. S., Stoof, S. C. M., & Buller, H. R. (2015). Theme 3: Non-invasive management of (recurrent) venous thromboembolism (VTE) and post thrombotic syndrome (PTS). Thrombosis Research, 136(Supplement 1), S13-S18. https://doi.org/10.1016/j.thromres.2015.07.036

Overview

Latest news & events

NWO Faculty of Impact grant awarded to Hongxing Luo

12 March 2026

Recap Anna Maria van Schurman Symposium 2026

11 March 2026

Arina ten Cate-Hoek

Associate professor