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Professorship Julie Staals

Professorship Julie Staals

22 April 2024

Dr Julie Staals (Dept. of Neurology) has been appointed as professor 'Neurovascular disease' as of 1 April 2024.

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ERC Advanced Grant awarded to Prof. Andy Baker

ERC Advanced Grant awarded to Prof. Andy Baker

15 April 2024

Prof. Andy Baker (Dept of Pathology) has been awarded a European Research Council (ERC) Advanced Grant of €2,5M for his research project PolymiRize: Poly-miRNA targeting to prevent and reverse complex tissue remodelling after acute cardiovascular events'.

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Carim Maastricht
Carim Maastricht

Wim van Zwam

Professor

Education/Training
• Medical study, MD (Free University, Amsterdam) 1989
• Tropical Medicine (Dutch Tropical Institute, Amsterdam) 1992
• Radiology (Maastricht University Medical Centre) 2002
• International Diplome in Neurovascular Diseases, MSc (Université Paris XI) 2004
 
Positions and Employment
• Resident Tropical Medicine (Surgery – Gynaecology) 1989 – 1992
Slotervaart General Hospital, Amsterdam
• Tropical Doctor, Medecins Sans Frontieres 1992 – 1994
Somalië, Laos, Sri Lanka
• Resident Radiology, MUMC+, Maastricht 1995 – 2002
• Interventional Radiology, Leuven, Belgium 2002
• Neuro-interventional Radiology, Tilburg 2002
• Neuro-interventional Radiology, Essen, Germany 2003
• Interventional Radiology, MUMC+, Maastricht 2003
 
Thesis, PhD: 2013
Aneurysmal subarachnoid hemorrhage: Imaging strategies and cost-effectiveness aspects in diagnostic work-up and post-therapeutic follow-up.
 
• PI of MACCA study (Magnetic resonance Angiography with Contrast in patients with Cerebra Aneurysms). Funding: 300k Euro from Profileringsfonds azM. 2006-2010 
• Co-PI, member of executive committee and imaging committee of the MRCLEAN trial (Multicenter Randomized Clinical trial of Endovascular treatment of Acute ischemic stroke in the Netherlands). 2010 - 2015
Funding: 800k Euro from Dutch Heart Foundaton; 500k Euro from unrestricted grants. 
 
Professional memberships: NVvR, NGIR, NNG, NVF, ESR, CIRSE, ESMINT, WFITN
Chair of Stroke Task Force, CIRSE
Board member of ESMINT
Member executive committee European Board of NeuroInterventions (EBNI)

PI of MRCLEAN_Late (MRCLEAN - patients arriving between 6 – 24 hrs after symptom onset), study under CONTRAST umbrella.
Co-PI, member of executive committee and imaging committee of CONTRAST (COnsortium for New Treatments in Acute Stroke).
Funding: 4000k Euro from Dutch Heart Foundaton; 4000k Euro from unrestricted grants. 200k Euro from Dutch Brain Council. 272k Euro from ZonMW
Member of executive committee MRCLEAN NoIV.
Wim-van-zwam

Department of Radiology and Nuclear Medicine
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
T: +31(0)43 387 69 09

  • 2018
    • Mulder, M. J. H. L., Jansen, I. G. H., Goldhoorn, R.-J. B., Venema, E., Chalos, V., Compagne, K. C. J., Roozenbeek, B., Lingsma, H. F., Schonewille, W. J., van den Wijngaard, I. R., Boiten, J., Vos, J. A., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., & MR CLEAN Registry Investigators (2018). Time to Endovascular Treatment and Outcome in Acute Ischemic Stroke: MR CLEAN Registry Results. Circulation, 138(3), 232-240. https://doi.org/10.1161/CIRCULATIONAHA.117.032600
    • Autar, A. S. A., Hund, H. M., Ramlal, S. A., Hansen, D., Nijeholt, G. J. L. A., Emmer, B. J., de Maat, M. P. M., Dippel, D. W. J., van der Lugt, A., van Es, A. C. G. M., van Beusekom, H. M. M., MR CLEAN Registry Investigators, Goldhoorn, R.-J., Staals, J., Postma - Jacobi, L., van Oostenbrugge, R. J., & van Zwam, W. (2018). High-Resolution Imaging of Interaction Between Thrombus and Stent-Retriever in Patients With Acute Ischemic Stroke. Journal of the American Heart Association, 7(13), Article 008563. https://doi.org/10.1161/JAHA.118.008563
    • Boers, A. M. M., Sales Barros, R., Jansen, I. G. H., Berkhemer, O. A., Beenen, L. F. M., Menon, B. K., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Slump, C. H., Majoie, C. B. L. M., & Marquering, H. A. (2018). Value of Quantitative Collateral Scoring on CT Angiography in Patients with Acute Ischemic Stroke. American Journal of Neuroradiology, 39(6), 1074-1082. https://doi.org/10.3174/ajnr.A5623
    • Kappelhof, M., Marquering, H. A., Berkhemer, O. A., Borst, J., van der Lugt, A., van Zwam, W. H., Vos, J. A., Nijeholt, G. L. A., Majoie, C. B. L. M., & Emmer, B. J. (2018). Accuracy of CT Angiography for Differentiating Pseudo-Occlusion from True Occlusion or High-Grade Stenosis of the Extracranial ICA in Acute Ischemic Stroke: A Retrospective MR CLEAN Substudy. American Journal of Neuroradiology, 39(5), 892-898. https://doi.org/10.3174/ajnr.A5601
    • Kimberly, W. T., Dutra, B. G., Boers, A. M. M., Alves, H. C. B. R., Berkhemer, O. A., van den Berg, L., Sheth, K. N., Roos, Y. B. W. E. M., van der Lugt, A., Beenen, L. F. M., Dippel, D. W. J., van Zwam, W. H., van Oostenbrugge, R. J., Lingsma, H. F., Marquering, H., Majoie, C. B. L. M., & MR CLEAN Investigators (2018). Association of Reperfusion With Brain Edema in Patients With Acute Ischemic Stroke A Secondary Analysis of the MR CLEAN Trial. JAMA Neurology, 75(4), 453-461. https://doi.org/10.1001/jamaneurol.2017.5162
    • Dijkland, S. A., Voormolen, D. C., Venema, E., Roozenbeek, B., Polinder, S., Haagsma, J. A., Nieboer, D., Chalos, V., Yoo, A. J., Schreuders, J., van der Lugt, A., Majoie, C. B. L. M., Roos, Y. B. W. E. M., van Zwam, W. H., van Oostenbrugge, R. J., Steyerberg, E. W., Dippel, D. W. J., Lingsma, H. F., & MR CLEAN Investigators (2018). Utility-Weighted Modified Rankin Scale as Primary Outcome in Stroke Trials A Simulation Study. Stroke, 49(4), 965-971. https://doi.org/10.1161/STROKEAHA.117.020194
    • Jansen, I. G. H., Mulder, M. J. H. L., Goldhoorn, R.-J. B., Emmer, B. J., van Es, A. C. G. M., Roozenbeek, B., Schonewille, W. J., van den Berg, R., Coutinho, J. M., Staals, J., Postma, A. A., Lycklama, G. J., Hofmeijer, J., Martens, J. M., den Hertog, H. M., Sturm, F. J. C., van der Worp, H. B., Lo, R. H., Heijboer, R. J. J., ... MR CLEAN Registry Investigators (2018). Endovascular treatment for acute ischaemic stroke in routine clinical practice: prospective, observational cohort study (MR CLEAN Registry). BMJ, 360, Article 949. https://doi.org/10.1136/bmj.k949
    • Jansen, I. G. H., van Vuuren, A. B., van Zwam, W. H., van den Wijngaard, I. R., Berkhemer, O. A., Lingsma, H. F., Slump, C. H., van Oostenbrugge, R. J., Treurniet, K. M., Dippel, D. W. J., van Walderveen, M. A. A., van der Lugt, A., Roos, Y. B. W. E. M., Marquering, H. A., Majoie, C. B. L. M., van den Berg, R., & MR CLEAN Trial Investigators (2018). Absence of Cortical Vein Opacification Is Associated with Lack of Intra-arterial Therapy Benefit in Stroke. Radiology, 286(2), 643-650. https://doi.org/10.1148/radiol.2017162445
    • Treurniet, K. M., Berkhemer, O. A., Immink, R. V., Lingsma, H. F., Ward-van der Stam, V. M. C., Hollmann, M. W., Vuyk, J., van Zwam, W. H., van der Lugt, A., van Oostenbrugge, R. J., Dippel, D. W. J., Coutinho, J. M., Roos, Y. B. W. E. M., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Investigators (2018). A decrease in blood pressure is associated with unfavorable outcome in patients undergoing thrombectomy under general anesthesia. Journal of Neurointerventional Surgery, 10(2), 107-111. https://doi.org/10.1136/neurintsurg-2017-012988
    • Alves, H. C., Treurniet, K. M., Dutra, B. G., Jansen, I. G. H., Boers, A. M. M., Santos, E. M. M., Berkhemer, O. A., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., van Oostenbrugge, R. J., Lingsma, H. F., Roos, Y. B. W. E. M., Yoo, A. J., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Trial Investigators (2018). Associations Between Collateral Status and Thrombus Characteristics and Their Impact in Anterior Circulation Stroke. Stroke, 49(2), 391-396. https://doi.org/10.1161/STROKEAHA.117.019509
    • Campbell, B. C. V., van Zwam, W. H., Goyal, M., Menon, B. K., Dippel, D. W. J., Demchuk, A. M., Bracard, S., White, P., Davalos, A., Majoie, C. B. L. M., van der Lugt, A., Ford, G. A., de la Ossa, N., Kelly, M., Bourcier, R., Donnan, G. A., Roos, Y. B. W. E. M., Bang, O. Y., Nogueira, R. G., ... HERMES Collaboration (2018). Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data. Lancet Neurology, 17(1), 47-53. https://doi.org/10.1016/S1474-4422(17)30407-6
  • 2017
    • Boers, A. M. M., Jansen, I. G. H., Berkhemer, O. A., Yoo, A. J., Lingsma, H. F., Slump, C. H., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Trial Investigators (2017). Collateral status and tissue outcome after intra-arterial therapy for patients with acute ischemic stroke. Journal of Cerebral Blood Flow and Metabolism, 37(11), 3589-3598. https://doi.org/10.1177/0271678X16678874
    • Compagne, K. C. J., van Es, A. C. G. M., Berkhemer, O. A., Borst, J., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., Marquering, H. A., Dippel, D. W. J., van der Lugt, A., Emmer, B. J., & MR CLEAN Trial Investigators (2017). Prevalence of Carotid Web in Patients with Acute Intracranial Stroke Due to Intracranial Large Vessel Occlusion. Radiology, 286(3), 1000-1007. https://doi.org/10.1148/radiol.2017170094
    • Heshmatollah, A., Fransen, P. S. S., Berkhemer, O. A., Beumer, D., van der Lugt, A., Majoie, C. B. L. M., Oostenbrugge, R. J., van Zwam, W. H., Koudstaal, P. J., Roos, Y. B. W. E. M., Dippel, D. W. J., & MR CLEAN Investigators (2017). Endovascular thrombectomy in patients with acute ischaemic stroke and atrial fibrillation: a MR CLEAN subgroup analysis. Eurointervention, 13(8), 996-1002. https://doi.org/10.4244/EIJ-D-16-00905
    • Schreuders, J., van den Berg, L. A., Fransen, P. S. S., Berkhemer, O. A., Beumer, D., Lingsma, H. F., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., de Kort, P. L. M., Roos, Y. B. W. E. M., Dippel, D. W. J., & MR CLEAN Investigators (2017). Quality of life after intra-arterial treatment for acute ischemic stroke in the MR CLEAN trialUpdate. International journal of stroke, 12(7), 708-712. https://doi.org/10.1177/1747493017706244
    • Ernst, M., Boers, A. M. M., Aigner, A., Berkhemer, O. A., Yoo, A. J., Roos, Y. B., Dippel, D. W. J., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Fiehler, J., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Trial Investigators (2017). Association of Computed Tomography Ischemic Lesion Location With Functional Outcome in Acute Large Vessel Occlusion Ischemic Stroke. Stroke, 48(9), 2426-2433. https://doi.org/10.1161/STROKEAHA.117.017513
    • Borst, J., Berkhemer, O. A., Santos, E. M. M., Yoo, A. J., den Blanken, M., Roos, Y. B. W. E. M., van Bavel, E., van Zwam, W. H., van Oostenbrugge, R. J., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Investigators (2017). Value of Thrombus CT Characteristics in Patients with Acute Ischemic Stroke. American Journal of Neuroradiology, 38(9), 1758-1764. https://doi.org/10.3174/ajnr.A5331
    • Venema, E., Boodt, N., Berkhemer, O. A., Rood, P. P. M., van Zwam, W. H., van Oostenbrugge, R. J., van der Lugt, A., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Lingsma, H. F., Dippel, D. W. J., & MR CLEAN Investigators (2017). Workflow and factors associated with delay in the delivery of intra-arterial treatment for acute ischemic stroke in the MR CLEAN trial. Journal of Neurointerventional Surgery, 10(5), 424-U19. https://doi.org/10.1136/neurintsurg-2017-013198
    • Mulder, M. J. H. L., Ergezen, S., Lingsma, H. F., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Nijeholt, G. L. A., Emmer, B. J., van der Worp, H. B., Nederkoorn, P. J., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., & Multicenter Randomized Clinical Tr (2017). Baseline Blood Pressure Effect on the Benefit and Safety of Intra-Arterial Treatment in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands). Stroke, 48(7), 1869-1876. https://doi.org/10.1161/STROKEAHA.116.016225
    • Yoo, A. J., Khatri, P., Mocco, J., Zaidat, O. O., Gupta, R., Frei, D., Lopes, D., Shownkeen, H., Berkhemer, O. A., Meyer, D., Hak, S. S., Kuo, S. S., Buell, H., Bose, A., Sit, S. P., THERAPY Trial Investigators, van Zwam, W., & von Kummer, R. (2017). Impact of Thrombus Length on Outcomes After Intra-Arterial Aspiration Thrombectomy in the THERAPY Trial. Stroke, 48(7), 1895-1900. https://doi.org/10.1161/STROKEAHA.116.016253
    • Berkhemer, O. A., Borst, J., Kappelhof, M., Yoo, A. J., van den Berg, L. A., Fransen, P. S. S., Beumer, D., Schonewille, W. J., Nederkoorn, P. J., Wermer, M. J. H., Marquering, H. A., Lingsma, H. F., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Dippel, D. W. J., van Zwam, W. H., Majoie, C. B. L. M., Emmer, B. J., van der Lugt, A., & MR CLEAN Investigators (2017). Extracranial Carotid Disease and Effect of Intra-arterial Treatment in Patients With Proximal Anterior Circulation Stroke in MR CLEAN. Annals of Internal Medicine, 166(12), 867-875. https://doi.org/10.7326/M16-1536
    • Beumer, D., van Boxtel, T. H., Schipperen, S., van Zwam, W. H., Nijeholt, G. J. L. A., Brouwer, P. A., Jenniskens, S. F. M., Schonewille, W. J., Vos, J. A., van der Lugt, A., Roos, Y. B., Majoie, C. B., van Oostenbrugge, R. J., Dippel, D. W. J., & MR CLEAN Pretrial Investigators (2017). The relationship between interventionists' experience and clinical and radiological outcome in intra-arterial treatment for acute ischemic stroke. A MR CLEAN pretrial survey. Journal of the Neurological Sciences, 377, 97-101. https://doi.org/10.1016/j.jns.2017.04.002
    • Mulder, M. J. H. L., Berkhemer, O. A., Fransen, P. S. S., van den Berg, L. A., Lingsma, H. F., den Hertog, H. M., Staals, J., Jenniskens, S. F. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., & MR CLEAN Investigators (2017). Does prior antiplatelet treatment improve functional outcome after intra-arterial treatment for acute ischemic stroke?International journal of stroke, 12(4), 368-376. https://doi.org/10.1177/1747493016677842
    • Venema, E., Mulder, M. J. H. L., Roozenbeek, B., Broderick, J. P., Yeatts, S. D., Khatri, P., Berkhemer, O. A., Emmer, B. J., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van Oostenbrugge, R. J., van Zwam, W. H., van der Lugt, A., Steyerberg, E. W., Dippel, D. W. J., & Lingsma, H. F. (2017). Selection of patients for intra-arterial treatment for acute ischaemic stroke: development and validation of a clinical decision tool in two randomised trials. BMJ, 357, Article j1710. https://doi.org/10.1136/bmj.j1710
    • Osei, E., den Hertog, H. M., Berkhemer, O. A., Fransen, P. S. S., Roos, Y. B. W. E. M., Beumer, D., van Oostenbrugge, R. J., Schonewille, W. J., Boiten, J., Zandbergen, A. A. M., Koudstaal, P. J., MR CLEAN Investigators, van Zwam, W., & Dippel, D. W. J. (2017). Admission Glucose and Effect of Intra-Arterial Treatment in Patients With Acute Ischemic Stroke. Stroke, 48(5), 1299-1305. https://doi.org/10.1161/STROKEAHA.116.016071
    • Bucker, A., Boers, A. M., Bot, J. C. J., Berkhemer, O. A., Lingsma, H. F., Yoo, A. J., Van Zwam, W. H., Van Oostenbrugge, R. J., Van der Lugt, A., Dippel, D. W. J., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Marquering, H. A., MR CLEAN Trial Investigators, & Multictr Randomized Clinical Trial (2017). Associations of Ischemic Lesion Volume With Functional Outcome in Patients With Acute Ischemic Stroke 24-Hour Versus 1-Week Imaging. Stroke, 48(5), 1233-1240. https://doi.org/10.1161/STROKEAHA.116.015156
    • Boers, A. M. M., Berkhemer, O. A., Slump, C. H., van Zwam, W. H., Roos, Y. B. W. E. M., van der Lugt, A., van Oostenbrugge, R. J., Yoo, A. J., Dippel, D. W. J., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Trial Investigators (2017). Topographic distribution of cerebral infarct probability in patients with acute ischemic stroke: mapping of intra-arterial treatment effect. Journal of Neurointerventional Surgery, 9(5), 431-436. https://doi.org/10.1136/neurintsurg-2016-012387
    • van den Berg, L. A., Dijkgraaf, M. G. W., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., Lingsma, H. F., Majoie, C. B. L. M., Dippel, D. W. J., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Roos, Y. B. W. E. M., & MR CLEAN Investigators (2017). Two-Year Outcome after Endovascular Treatment for Acute Ischemic Stroke. New England Journal of Medicine, 376(14), 1341-1349. https://doi.org/10.1056/NEJMoa1612136
    • Mulder, M. J. H. L., Venema, E., Roozenbeek, B., Broderick, J. P., Yeatts, S. D., Khatri, P., Berkhemer, O. A., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van Oostenbrugge, R. J., van Zwam, W. H., van der Lugt, A., Steyerberg, E. W., Dippel, D. W. J., & Lingsma, H. F. (2017). Towards personalised intra- arterial treatment of patients with acute ischaemic stroke: a study protocol for development and validation of a clinical decision aid. BMJ Open, 7(3), Article 013699. https://doi.org/10.1136/bmjopen-2016-013699
    • Wagemans, B. A. J. M., van Zwam, W. H., Nelemans, P. J., van Oostenbrugge, R. J., & Postma, A. A. (2017). 4D-CTA improves diagnostic certainty and accuracy in the detection of proximal intracranial anterior circulation occlusion in acute ischemic stroke. PLOS ONE, 12(2), Article 0172356. https://doi.org/10.1371/journal.pone.0172356
  • 2016
    • Treurniet, K. M., Yoo, A. J., Berkhemer, O. A., Lingsma, H. F., Boers, A. M. M., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Sprengers, M. E. S., Jenniskens, S. F. M., Nijeholt, G. J. L. A., van Walderveen, M. A. A., Bot, J. C. J., Beenen, L. F. M., van den Berg, R., van Zwam, W. H., van der Lugt, A., van Oostenbrugge, R. J., Dippel, D. W. J., ... Majoie, C. B. L. M. (2016). Clot Burden Score on Baseline Computerized Tomographic Angiography and Intra-Arterial Treatment Effect in Acute Ischemic Stroke. Stroke, 47(12), 2972-2978. https://doi.org/10.1161/STROKEAHA.116.014565
    • van den Berg, L. A., Dijkgraaf, M. G. W., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., Lingsma, H., Majoie, C. B. M., Dippel, D. W. J., van der Lugt, A. J., van Oostenbrugge, R. J., van Zwam, W. H., & Roos, Y. B. W. E. M. (2016). Two-year clinical follow-up of the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in The Netherlands (MR CLEAN): design and statistical analysis plan of the extended follow-up study. Trials, 17, Article 555. https://doi.org/10.1186/s13063-016-1669-6
    • Dippel, D. W., Majoie, C. B., Roos, Y. B., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Lingsma, H. F., Koudstaal, P. J., Treurniet, K. M., van den Berg, L. A., Beumer, D., Fransen, P. S., & Berkhemer, O. A. (2016). Influence of Device Choice on the Effect of Intra-Arterial Treatment for Acute Ischemic Stroke in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands). Stroke, 47(10), 2574-2581. https://doi.org/10.1161/STROKEAHA.116.013929
    • Saver, J. L., Goyal, M., van der Lugt, A., Menon, B. K., Majoie, C. B. L. M., Dippel, D. W., Campbell, B. C., Nogueira, R. G., Demchuk, A. M., Tomasello, A., Cardona, P., Devlin, T. G., Frei, D. F., de Rochemont, R. D. M., Berkhemer, O. A., Jovin, T. G., Siddiqui, A. H., van Zwam, W. H., Davis, S. M., ... Hill, M. D. (2016). Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis. JAMA-Journal of the American Medical Association, 316(12), 1279-1288. https://doi.org/10.1001/jama.2016.13647
    • Al-Ali, F., Berkhemer, O. A., Yousman, W. P., Elias, J. J., Bender, E. N., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Dillon, W. P., & Majoie, C. B. L. M. (2016). The Capillary Index Score as a Marker of Viable Cerebral Tissue: Proof of Concept-The Capillary Index Score in the MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands) Trial. Stroke, 47(9), 2286-2291. https://doi.org/10.1161/STROKEAHA.116.013513
    • Berkhemer, O. A., van den Berg, L. A., Fransen, P. S. S., Beumer, D., Yoo, A. J., Lingsma, H. F., Schonewille, W. J., van den Berg, R., Wermer, M. J. H., Boiten, J., Nijeholt, G. J. L., Nederkoorn, P. J., Hollmann, M. W., van Zwam, W. H., van der Lugt, A., van Oostenbrugge, R. J., Majoie, C. B. L. M., Dippel, D. W. J., & Roos, Y. B. W. E. M. (2016). The effect of anesthetic management during intra-arterial therapy for acute stroke in MR CLEAN. Neurology, 87(7), 656-664. https://doi.org/10.1212/WNL.0000000000002976
    • Mulder, M. J. H. L., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Lingsma, H. F., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., & Dippel, D. W. J. (2016). Treatment in patients who are not eligible for intravenous alteplase: MR CLEAN subgroup analysis. International journal of stroke, 11(6), 637-645. https://doi.org/10.1177/1747493016641969
    • Yoo, A. J., Berkhemer, O. A., Fransen, P. S. S., van den Berg, L. A., Beumer, D., Lingsma, H. F., Schonewille, W. J., Sprengers, M. E. S., van den Berg, R., van Walderveen, M. A. A., Beenen, L. F. M., Wermer, M. J. H., Nijeholt, G. J. L. A., Boiten, J., Jenniskens, S. F. M., Bot, J. C. J., Boers, A. M. M., Marquering, H. A., Roos, Y. B. W. E. M., ... Majoie, C. B. L. M. (2016). Effect of baseline Alberta Stroke Program Early CT Score on safety and efficacy of intra-arterial treatment: a subgroup analysis of a randomised phase 3 trial (MR CLEAN). Lancet Neurology, 15(7), 685-694. https://doi.org/10.1016/S1474-4422(16)00124-1
    • Crijnen, Y. S., Nouwens, F., de Lau, L. M. L., Visch-Brink, E. G., van de Sandt-Koenderman, M. W. M. E., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Lingsma, H. F., Roos, Y. B. W. E. M., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., & Dippel, D. W. J. (2016). Early effect of intra-arterial treatment in ischemic stroke on aphasia recovery in MR CLEAN. Neurology, 86(22), 2049-2055. https://doi.org/10.1212/WNL.0000000000002724
    • Beumer, D., Rozeman, A. D., Nijeholt, G. J. L. A., Brouwer, P. A., Jenniskens, S. F. M., Algra, A., Boiten, J., Schonewille, W., van Oostenbrugge, R. J., Dippel, D. W. J., & van Zwam, W. H. (2016). The effect of age on outcome after intraarterial treatment in acute ischemic stroke: a MR CLEAN pretrial study. BMC Neurology, 16, Article 68. https://doi.org/10.1186/s12883-016-0592-5
    • Goyal, M., Menon, B. K., van Zwam, W. H., Dippel, D. W. J., Mitchell, P. J., Demchuk, A. M., Davalos, A., Majoie, C. B. L. M., van der Lugt, A., de Miquel, M. A., Donnan, G. R. A., Roos, Y. B. W. E. M., Bonafe, A., Jahan, R., Diener, H.-C., van den Berg, L. A., Levy, E. I., Berkhemer, O. A., Pereira, V. M., ... Jovin, T. G. (2016). Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet, 387(10029), 1723-1731. https://doi.org/10.1016/S0140-6736(16)00163-X
    • Berkhemer, O. A., Jansen, I. G. H., Beumer, D., Fransen, P. S. S., van den Berg, L. A., Yoo, A. J., Lingsma, H. F., Sprengers, M. E. S., Jenniskens, S. F. M., Lycklama a Nijeholt, G. J., van Walderveen, M. A. A., van den Berg, R., Bot, J. C. J., Beenen, L. F. M., Boers, A. M. M., Slump, C. H., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Dippel, D. W. J., ... Majoie, C. B. L. M. (2016). Collateral Status on Baseline Computed Tomographic Angiography and Intra-Arterial Treatment Effect in Patients With Proximal Anterior Circulation Stroke. Stroke, 47(3), 768-776. https://doi.org/10.1161/STROKEAHA.115.011788
    • Santos, E. M. M., Marquering, H. A., den Blanken, M. D., Berkhemer, O. A., Boers, A. M. M., Yoo, A. J., Beenen, L. F., Treurniet, K. M., Wismans, C., van Noort, K., Lingsma, H. F., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Niessen, W. J., & Majoie, C. B. (2016). Thrombus Permeability Is Associated With Improved Functional Outcome and Recanalization in Patients With Ischemic Stroke. Stroke, 47(3), 732-741. https://doi.org/10.1161/STROKEAHA.115.011187
    • MR CLEAN Investigators, van Zwam, W., & van Oostenbrugge, R. J. (2016). Observer variability of absolute and relative thrombus density measurements in patients with acute ischemic stroke. Neuroradiology, 58(2), 133-139. https://doi.org/10.1007/s00234-015-1607-4
    • Fransen, P. S. S., Berkhemer, O. A., Lingsma, H. F., Beumer, D., van den Berg, L. A., Yoo, A. J., Schonewille, W. J., Vos, J. A., Nederkoorn, P. J., Wermer, M. J. H., van Walderveen, M. A. A., Staals, J., Hofmeijer, J., van Oostayen, J. A., Nijeholt, G. J. L. A., Boiten, J., Brouwer, P. A., Emmer, B. J., de Bruijn, S. F., ... Dippel, D. W. J. (2016). Time to Reperfusion and Treatment Effect for Acute Ischemic Stroke A Randomized Clinical Trial. JAMA Neurology, 73(2), 190-196. https://doi.org/10.1001/jamaneurol.2015.3886
    • MR CLEAN Investigators, van Oostenbrugge, R. J., & van Zwam, W. (2016). Automated Entire Thrombus Density Measurements for Robust and Comprehensive Thrombus Characterization in Patients with Acute Ischemic Stroke. PLOS ONE, 11(1), Article e0145641. https://doi.org/10.1371/journal.pone.0145641
    • Wahlgren, N., Moreira, T., Michel, P., Steiner, T., Jansen, O., Cognard, C., Mattle, H. P., van Zwam, W., Holmin, S., Tatlisumak, T., Petersson, J., Caso, V., Hacke, W., Mazighi, M., Arnold, M., Fischer, U., Szikora, I., Pierot, L., Fiehler, J., ... Lees, K. R. (2016). Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN. International journal of stroke, 11(1), 134-147. https://doi.org/10.1177/1747493015609778
    • de Ridder, I. R., Fransen, P. S. S., Beumer, D., Berkhemer, O. A., van den Berg, L. A., Wermer, M. J., Lingsma, H., van Zwam, W. H., Roos, Y. B., van Oostenbrugge, R. J., Majoie, C. B., van der Lugt, A., & Dippel, D. W. J. (2016). Is Intra-Arterial Treatment for Acute Ischemic Stroke Less Effective in Women than in Men?Interventional Neurology, 5(3-4), 174-178. https://doi.org/10.1159/000447331
    • Beumer, D., Mulder, M. J. H. L., Saiedie, G., Fonville, S., van Oostenbrugge, R. J., van Zwam, W., Homburg, P. J., van der Lugt, A., & Dippel, D. W. J. (2016). Occurence of intracranial large vessel occlusion in consecutive, non-referred patients with acute ischemic stroke. Neurovascular Imaging, 2, Article 11. https://doi.org/10.1186/s40809-016-0022-5
  • 2015
    • Sailer, A. M., van Zwam, W. H., Wildberger, J. E., & Grutters, J. P. C. (2015). Cost-effectiveness modelling in diagnostic imaging: a stepwise approach. European Radiology, 25(12), 3629-3637. https://doi.org/10.1007/s00330-015-3770-8
Overview