Wim van Zwam

Professor

Education/Training
• Medical study, MD (Free University, Amsterdam) 1989
• Tropical Medicine (Dutch Tropical Institute, Amsterdam) 1992
• Radiology (Maastricht University Medical Centre) 2002
• International Diplome in Neurovascular Diseases, MSc (Université Paris XI) 2004
 
Positions and Employment
• Resident Tropical Medicine (Surgery – Gynaecology) 1989 – 1992
Slotervaart General Hospital, Amsterdam
• Tropical Doctor, Medecins Sans Frontieres 1992 – 1994
Somalië, Laos, Sri Lanka
• Resident Radiology, MUMC+, Maastricht 1995 – 2002
• Interventional Radiology, Leuven, Belgium 2002
• Neuro-interventional Radiology, Tilburg 2002
• Neuro-interventional Radiology, Essen, Germany 2003
• Interventional Radiology, MUMC+, Maastricht 2003
 
Thesis, PhD: 2013
Aneurysmal subarachnoid hemorrhage: Imaging strategies and cost-effectiveness aspects in diagnostic work-up and post-therapeutic follow-up.
 
• PI of MACCA study (Magnetic resonance Angiography with Contrast in patients with Cerebra Aneurysms). Funding: 300k Euro from Profileringsfonds azM. 2006-2010 
• Co-PI, member of executive committee and imaging committee of the MRCLEAN trial (Multicenter Randomized Clinical trial of Endovascular treatment of Acute ischemic stroke in the Netherlands). 2010 - 2015
Funding: 800k Euro from Dutch Heart Foundaton; 500k Euro from unrestricted grants. 
 
Professional memberships: NVvR, NGIR, NNG, NVF, ESR, CIRSE, ESMINT, WFITN
Chair of Stroke Task Force, CIRSE
Board member of ESMINT
Member executive committee European Board of NeuroInterventions (EBNI)

PI of MRCLEAN_Late (MRCLEAN - patients arriving between 6 – 24 hrs after symptom onset), study under CONTRAST umbrella.
Co-PI, member of executive committee and imaging committee of CONTRAST (COnsortium for New Treatments in Acute Stroke).
Funding: 4000k Euro from Dutch Heart Foundaton; 4000k Euro from unrestricted grants. 200k Euro from Dutch Brain Council. 272k Euro from ZonMW
Member of executive committee MRCLEAN NoIV.

Department of Radiology and Nuclear Medicine
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
T: +31(0)43 387 69 09

  • 2026
    • van der Sluijs, P. M., Su, R., Schoon, B. A., van de Graaf, R. A., Cornelissen, S. A. P., van Es, A. C. G. M., van Doormaal, P. J., Hofmeijer, J., Roozenbeek, B., van Zwam, W. H., van der Lugt, A., van Walsum, T., & MR CLEAN Registry Investigators (2026). Perfusion Angiography in Reperfused Patients with Ischemic Stroke: differentiating between favorable and unfavorable outcome. American Journal of Neuroradiology, 47(1), 59-65. Article ajnr.A8936. https://doi.org/10.3174/ajnr.A8936
    • Doheim, M. F., Knapen, R. R. M. M., Dippel, D. W. J., Staals, J., Hofmeijer, J., van Es, A. C. G. M., Coutinho, J. M., van der Leij, C., Nogueira, R. G., van Oostenbrugge, R. J., van Zwam, W. H., & MR CLEAN Registry Investigators (2026). Association of anesthesia strategies with outcomes in endovascular treatment for distal and medium vessel occlusions: A propensity score-matched analysis of the MR CLEAN registry and meta-analysis. European Stroke Journal, 11(1), Article 23969873251352406. https://doi.org/10.1177/23969873251352406
    • Kersten, C., Zandbergen, A. A. M., Olthuis, S. G. H., Van Zwam, W., Hofmeijer, J., Emmer, B. J., Hoving, J. W., van Oostenbrugge, R. J., & den Hertog, H. (2026). Hyperglycaemia does not modify the efficacy of endovascular therapy in the late time window (6-24 hours). International journal of stroke, 21(1), 138-145. https://doi.org/10.1177/17474930251358824
  • 2025
    • Knapen, R. R. M. M., Doheim, M. F., Audebert, H. J., Mont'Alverne, F., Puetz, V., Michel, P., Liu, X., Dai, Q., Hu, W., Tao, C., Liu, R., Xu, P., Li, C., Ji, X., Jovin, T. G., van der Leij, C., van Oostenbrugge, R. J., van Zwam, W. H., Nogueira, R. G., ... VERITAS Collaborators (2025). Intravenous Thrombolysis Prior to Endovascular Treatment in Basilar Artery Occlusions: A Patient Pooled Analysis of Four Randomized Controlled Trials. Cardiovascular and Interventional Radiology, 48(12), 1869-1877. https://doi.org/10.1007/s00270-025-04251-z
    • Mathijssen, E. G., Trappenburg, J. C., Alberts, M. J., Balguid, A., Dempsey, R. J., Goyal, M., de Greef, B. T., Hummel, M. J., Iihara, K., Leira, E. C., Lim, W., Lip, G. Y., Madeddu, P., Marshall, R. S., McCabe, D. J., Muda, A. S., Nikas, D. N., Ntaios, G., Quinn, T. J., ... Schuit, E. (2025). Prioritizing gaps in stroke care: A two-round Delphi process. European Stroke Journal, 10(4), 1479-1488. https://doi.org/10.1177/23969873251329841
    • Dassen, S., Van Es, A., Roozenbeek, B., Van De Graaf, R., Roos, Y., Majoie, C., Ghariq, E., Kruyt, N., Fischer, U., Van Oostenbrugge, R., Van Zwam, W., & Staals, J. (2025). Time to Endovascular Treatment and Clinical Outcome in Acute Ischemic Stroke With M2-Segment Occlusion. Journal of the American Heart Association, 14(22), 1-10. Article e043984. https://doi.org/10.1161/JAHA.125.043984
    • Mojtahedi, M., de Vries, L., van Poppel, L., Hoving, J. W., ter Avest, T., Dippel, D., Roos, Y., van Zwam, W., Majoie, C., Marquering, H., & Emmer, B. (2025). Estimation of Acute Infarct Core and Hypoperfused Region from Baseline Noncontrast Computed Tomography and Computed Tomography Angiography Scans of Patients with Ischemic Stroke. Stroke: vascular and interventional neurology, 5(6), Article e001890. https://doi.org/10.1161/SVIN.125.001890
    • Yang, W., Cavalcante, F., Treurniet, K. M., Kappelhof, M., Bruggeman, A. A. E., Wolff, L., Rinkel, L. A., Lecouffe, N. E., Jansen, I. G. H., Venkatesh, A., Berkhemer, O. A., Hoorn, A. V. D., Sprengers, M. E., Emmer, B. J., Coutinho, J. M., Roos, Y. B. W. E. M., van Zwam, W., van Oostenbrugge, R., Marquering, H. A., & Majoie, C. B. L. M. (2025). Arterial collateral status and treatment effect of intravenous alteplase thrombolysis prior to endovascular treatment in patients with anterior circulation large vessel occlusion: prespecified analysis of the MR CLEAN-NO IV trial. Journal of Neurointerventional Surgery, 17(10), 1051-1058. https://doi.org/10.1136/jnis-2025-023054
    • Huijberts, I., Oostenbrugge, R. J. V., Zwam, W. H. V., Postma, A. A., & Pinckaers, F. M. E. (2025). Costs of productivity loss up to two years after ischaemic stroke. European Journal of Health Economics. https://doi.org/10.1007/s10198-025-01856-6
    • Vermeulen, E., Bruneau, M., Potters, F., Podlogar, M., Jolink, W. M. T., Haeren, R., Wagemans, B. A. J. M., Staals, J., Meijer, F. J. A., Klijn, C. J. M., Vinke, S., De Vries, J., van Zwam, W. H., & Boogaarts, H. D. (2025). Evaluating the need for late angiography for complete obliteration of AVMs after endovascular treatment: collaborative AVM center experience and a systematic review. Journal of Neurointerventional Surgery. https://doi.org/10.1136/jnis-2025-024046