Werner Mess

Professor

Prof. Werner Mess received his medical degree in 1989 at the University of Düsseldorf, whereafter he was a resident in neurology in Mannheim/Heidelberg and Düsseldorf until 1994. As a certified neurologist he went to Nieuwegein (NL), where he worked as a clinical neurophysiologist for two years. In 1997, he became staff member and subsequently (2006) chairman of the Department of Clinical Neurophysiology at Maastricht University. In 2003, he received his PhD in Medicine at Maastricht University on the physical properties of microembolus detection and in 2007 became professor of clinical neurophysiology.

He has been involved in ultrasound since his first scientific activities resulting in a thesis based on CW Doppler measurements of the carotid and vertebral arteries in patients with an asymptomatic vascular disease. Since then, he has performed and participated in multiple studies on plaque morphology as well as microembolus detection. The latter led to his PhD degree and focussed on the physical aspects of the method. Currently, he focusses on long-term embolus detection, as well as the combined evaluation of functional, and anatomical properties of the carotid artery by means of ultrasound. He is an internationally recognised expert in this field and a member of the ESNCH and board member of the Neurosonology Research Group.

Department of Clinical Neurophysiology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
T
: +31(0)43 387 52 73

  • 2026
    • Hodzelmans, J. J. A., Janssen, M. L. F., Reulen, J. P. H., Koster, A., Schaper, N. C., Mess, W. H., & Sutedja, N. A. (2026). Risk Factors of Sural Nerve Axonal Degeneration Using Clinically Relevant Thresholds in Context of Glucose Metabolism: The Maastricht Study. Muscle & nerve, 73(2), 283-291. https://doi.org/10.1002/mus.70088
    • Knapen, S. E., Hinsenveld, W. H., Janssen, M. L. F., Mess, W. H., Drenthen, J., & Tannemaat, M. R. (2026). Utility of continuous EEG monitoring in postanoxic coma: a retrospective multicenter study. Critical Care, 30(1), Article 9. https://doi.org/10.1186/s13054-025-05773-1
  • 2025
    • Okoro, C., van der Kallen, C. J. H., Mokhtar, S. B. A., Zhou, T. L., Berendschot, T. T. J. M., Koster, A., Reesink, K., Reulen, J., Mess, W. H., Webers, C. A. B., Kroon, A., & Stehouwer, C. D. A. (2025). Arterial stiffness is associated with small and large fiber neuropathy: The Maastricht Study. Journal of Hypertension, 43(12), 1945-1952. https://doi.org/10.1097/HJH.0000000000004126
    • Kishna, Y. S., Baars, S., van der Horst, I. C. C., Mess, W. H., Hendrix, R., Delnoij, T. S. R., & Aries, M. (2025). Cerebral monitoring responses to bedside physiological challenges in comatose post-cardiac arrest patients. Journal of Clinical Monitoring and Computing. Advance online publication. https://doi.org/10.1007/s10877-025-01393-w
    • Kishna, Y. S., Mess, W. H., Hendrix, R. H. J., Otten, J., & Aries, M. (2025). Challenges in the Interpretation of Hyperechoic Reflexes in Multiplanar Ultrasound Optic Nerve Sheath Diameter Analysis. Neurocritical Care. https://doi.org/10.1007/s12028-025-02413-y
    • Schenck, H., De Ridder, I., Gommer, E., Mess, W., Hoogland, G., Teernstra, O., Dings, J., Kuijk, S. V., Temel, Y., & Haeren, R. (2025). In vivo glycocalyx assessment in aneurysmal subarachnoid hemorrhage patients: protocol for a prospective observational feasibility study. Pilot and Feasibility Studies, 11(1), Article 154. https://doi.org/10.1186/s40814-025-01735-0
    • Molad, J., Miwa, K., Nash, P. S., Ambler, G., Best, J., Wilson, D., Hallevi, H., Fandler-Höfler, S., Eppinger, S., Du, H., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y. H., Goeldlin, M. B., Beyeler, M., Bücke, P., El-Koussy, M., Mattle, H. P., Panos, L. D., ... Et al. (2025). Increased risk of recurrent stroke in patients with impaired kidney function: results of a pooled analysis of individual patient data from the MICON international collaboration. Journal of Neurology Neurosurgery and Psychiatry, 96(9), 842-851. Article e335110. https://doi.org/10.1136/jnnp-2024-335110
    • Tziotziou, A., Liu, Y., Fontana, F., Bierens, J., Nederkoorn, P. J., de Jong, P. A., Kooi, M. E., Mess, W., van der Lugt, A., van der Steen, A. F. W., Bos, D., Wentzel, J. J., & Akyildiz, A. C. (2025). Pressure- and flow-driven biomechanical factors associate with carotid atherosclerosis assessed by computed tomography angiography. Atherosclerosis, 408, Article 120415. https://doi.org/10.1016/j.atherosclerosis.2025.120415
    • Aizaz, M., Bierens, J., Gijbels, M. J. J., Schreuder, T. H. C. M. L., van Orshoven, N. P., Daemen, J.-W. H. C., Mess, W. H., Flohr, T., van Oostenbrugge, R. J., Postma, A. A., & Kooi, M. E. (2025). Differentiation of Atherosclerotic Carotid Plaque Components With Dual-Energy Computed Tomography. Investigative Radiology, 60(8), 508-516. https://doi.org/10.1097/RLI.0000000000001153
    • Schuurman, B., Mess, W. H., Postma, A. A., Staals, J., & van Weert, S. (2025). Pearls & Oy-sters: Eagle Syndrome in a Patient With Neurologic Deficit Upon Head Rotation. Neurology, 105(1), Article e213764. https://doi.org/10.1212/WNL.0000000000213764