Vanessa van Empel

Associate professor

Dr Vanessa van Empel studied Medicine at the University of Maastricht. During her studies, she started her PhD on the topic heart failure. She obtained her PhD from the University of Utrecht in 2007. Subsequently she started her training as a cardiologist at the Maastricht University Medical Centre. After finishing her cardiology training in 2011, Vanessa was rewarded the ICIN fellowship, which enabled her to do a post-doctoral fellowship at the Alfred Hospital in Melbourne, Australia, where she gained more expertise in the field of heart failure with preserved ejection fraction (HFpEF). She now is a staff member at the Maastricht UMC+ with an expertise in heart failure, and heart failure with preserved ejection fraction specifically.

Her clinical work and research has been dedicated to HFpEF. She initiated the HFpEF clinic in Maastricht, which started in 2015, and is responsible for the Maastricht HFpEF cohort. She obtained a grant 'Vrouwelijk Hartfalen' from the Health Foundation Limburg together with Prof. Blanche Schroen, is co-PI on the CVON project Early detection of HFpEF and is project leader of the CVON SHE-PREDICT-HF, which studies sex differences in HFpEF. These projects allow her to continue her research on HFpEF with special focus on cardiovascular imaging, biomarkers and microvascular dysfunction.

Department of Cardiology
P. Debeyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: Maastricht UMC+ level 3
T: +31(0)43 387 70 95

  • 2022
    • Remmelzwaal, S., van Oort, S., Handoko, M. L., van Empel, V., Heymans, S. R. B., & Beulens, J. W. J. (2022). Inflammation and heart failure: a two-sample Mendelian randomization study. Journal of Cardiovascular Medicine, 23(11), 728-735. https://doi.org/10.2459/JCM.0000000000001373
    • van der Velden, R. M. J., Hermans, A. N. L., Pluymaekers, N. A. H. A., Gawalko, M., Elliott, A., Hendriks, J. M., Franssen, F. M. E., Slats, A. M., van Empel, V. P. M., Van Gelder, I. C., Thijssen, D. H. J., Eijsvogels, T. M. H., Leue, C., Crijns, H. J. G. M., Linz, D., & Simons, S. O. (2022). Dyspnea in patients with atrial fibrillation: Mechanisms, assessment and an interdisciplinary and integrated care approach. IJC Heart and Vasculature, 42, [101086]. https://doi.org/10.1016/j.ijcha.2022.101086
    • Javaheri, A., Diab, A., Zhao, L., Qian, C., Cohen, J. B., Zamani, P., Kumar, A., Wang, Z., Ebert, C., Maranville, J., Kvikstad, E., Basso, M., van Empel, V., Richards, A. M., Doughty, R. N., Rietzschel, E., Kammerhoff, K., Gogain, J., Schafer, P., ... Chirinos, J. A. (2022). Proteomic Analysis of Effects of Spironolactone in Heart Failure With Preserved Ejection Fraction. Circulation-Heart Failure, 15(9), [e009693]. https://doi.org/10.1161/CIRCHEARTFAILURE.121.009693
    • Henkens, M. T. H. M., Martinez, H. L., Weerts, J., Sammani, A., Raafs, A. G., Verdonschot, J. A. J., van de Leur, R. R., Sikking, M. A., Stroeks, S., van Empel, V. P. M., Brunner-La Rocca, H. P., van Stipdonk, A. M. W., Farmakis, D., Hazebroek, M. R., Vernooy, K., Bayes-de-Luna, A., Asselbergs, F. W., Bayes-Genis, A., & Heymans, S. R. B. (2022). Interatrial Block Predicts Life-Threatening Arrhythmias in Dilated Cardiomyopathy. Journal of the American Heart Association, 11(14), [e025473]. https://doi.org/10.1161/JAHA.121.025473
    • Verhaert, D. V. M., Linz, D., Chaldoupi, S. M., Westra, S. W., den Uijl, D. W., Philippens, S., Kerperien, M., Habibi, Z., Vorstermans, B., ter Bekke, R. M. A., Beukema, R. J., Evertz, R., Hemels, M. E. W., Luermans, J. G. L. M., Manusama, R., Lankveld, T. A. R., van der Heijden, C. A. J., Bidar, E., Hermans, B. M., ... Schotten, U. (2022). Rationale and Design of the ISOLATION Study: A Multicenter Prospective Cohort Study Identifying Predictors for Successful Atrial Fibrillation Ablation in an Integrated Clinical Care and Research Pathway. Frontiers in cardiovascular medicine, 9, [879139]. https://doi.org/10.3389/fcvm.2022.879139
    • Weerts, J., Mourmans, S. G. J., Eringa, E., & van Empel, V. P. M. (2022). Improving insights into the heterogeneous HFpEF syndrome through microvascular research. Journal of Molecular and Cellular Cardiology, 167, 106-108. https://doi.org/10.1016/j.yjmcc.2022.04.001
    • Henkens, M. T. H. M., van Ommen, A. M., Remmelzwaal, S., Valstar, G. B., Wang, P., Verdonschot, J. A. J., Hazebroek, M. R., Hofstra, L., Empel, V. P. M., Beulens, J. W. J., Ruijter, H. M., & Heymans, S. R. B. (2022). The HFA-PEFF score identifies 'early-HFpEF' phenogroups associated with distinct biomarker profiles. Esc heart failure, 9(3), 2032-2036. https://doi.org/10.1002/ehf2.13861
    • Henkens, M. T. H. M., Weerts, J., Verdonschot, J. A. J., Raafs, A. G., Stroeks, S., Sikking, M. A., Amin, H., Mourmans, S. G. J., Geraeds, C. B. G., Sanders-van Wijk, S., Aizpurua, A. B., Uszko-Lencer, N. H. M. K., Krapels, I. P. C., Wolffs, P. F. G., Brunner, H. G., Leeuwen, R. E. W., Verhesen, W., Schalla, S. M., van Stipdonk, A. W. M., ... Heymans, S. R. B. (2022). Improving diagnosis and risk stratification across the ejection fraction spectrum: the Maastricht Cardiomyopathy registry. Esc heart failure, 9(2), 1463-1470. https://doi.org/10.1002/ehf2.13833
    • van Woerden, G., van Veldhuisen, D. J., Gorter, T. M., Ophuis, B., Saucedo-Orozco, H., van Empel, V. P. M., Willems, T. P., Geelhoed, B., Rienstra, M., & Westenbrink, B. D. (2022). The value of echocardiographic measurement of epicardial adipose tissue in heart failure patients. Esc heart failure, 9(2), 953-957. https://doi.org/10.1002/ehf2.13828
    • van Woerden, G., van Veldhuisen, D. J., Manintveld, O. C., van Empel, V. P. M., Willems, T. P., de Boer, R. A., Rienstra, M., Westenbrink, B. D., & Gorter, T. M. (2022). Epicardial Adipose Tissue and Outcome in Heart Failure With Mid-Range and Preserved Ejection Fraction. Circulation-Heart Failure, 15(3), [009238]. https://doi.org/10.1161/CIRCHEARTFAILURE.121.009238