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Catheter treatment is not only effective, but also cost-effective for ischemic stroke

Catheter treatment is not only effective, but also cost-effective for ischemic stroke

29 September 2026

With ischemic stroke, every minute counts. However, many patients do not seek hospital care until it is too late, for example, because symptoms are not immediately recognized or because people wake up with signs of neurological deficits. As a result, a group of patients is no longer eligible for catheter treatment. 

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Platelets: more than a band-aid

Platelets: more than a band-aid

23 September 2026

Some processes in our body might seem obvious to us. If you cut your finger, the bleeding will stop shortly and form a scab. Behind that seemingly simple process hides a sophisticated system of platelets and clotting factors. By now, we know that platelets do much more than halt bleeding: they function as information carriers and regulators of disease processes. 

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Carim Maastricht
Carim Maastricht

Uli Schotten

Professor

Professor Uli Schotten studied medicine at the universities of Aachen, Glasgow, and Valetta. After four years of training in cardiology at the University Hospital of Aachen, he joined the Department of Physiology at Maastricht University in 1998, first as a scholar of the Academy of Sciences of North-Rhine Westfalia and from 1999 on as a staff member of the department. He defended his thesis 'Mechanisms of Atrial Paralysis in Atrial Fibrillation' at Maastricht University in 2003, and received his habilitation in Experimental Cardiology at the University Hospital in Aachen in 2004. Since 2007, he is Principal Investigator at CARIM. In 2011, he was appointed Professor of Cardiac Electrophysiology and became chairman of the Department of Physiology in 2019.

His research interests include cellular and integrated actions of antiarrhythmic drugs, the development of substrates for the perpetuation of atrial fibrillation, invasive and non-invasive quantification of the substrate of atrial fibrillation, interaction between atrial fibrillation and activation of the coagulation system, and three-dimensional computer models of atrial fibrillation. He is coordinator of the CVON network RACE V and PI in numerous national and international research networks. He was member of the European task force for the development of the ESC guidelines for management of atrial fibrillation in 2010, 2012, and 2016. Furthermore, he is member of the Executive Committee of the Network of Competence for Atrial Fibrillation (AFNET), co-founder of the Maastricht University spin-off company YourRhythmics BV, and acts as the chairman of the Strategic board of CARIM.

Uli-schotten

Department of Physiology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: 3.130
T: +31(0)43 388 12 00

  • 2026
    • Schotten, U., & Kirchhof, P. (2026). Quantifying atrial fibrillation to improve risk estimation: the growing role of AF burden and a new density kid on the block. European Heart Journal, 47(36), 5125-5127. https://doi.org/10.1093/eurheartj/ehag298
    • Marques, V. G., Gharaviri, A., Pezzuto, S., Guasch, E., Mont, L., Bonizzi, P., Zeemering, S., & Schotten, U. (2026). Analysis of the Effect of Anatomical Variability on Atrial Fibrillation Dynamics Through a Novel Framework for Personalised Atrial Model Generation. Annals of Biomedical Engineering. https://doi.org/10.1007/s10439-026-04265-9
    • Winters, J., Kawczynski, M., Gilbers, M., Isaacs, A., Zeemering, S., Habibi, Z., Rienstra, M., van Gelder, I., Maesen, B., Bidar, E., Verheule, S., & Schotten, U. (2026). Histological evaluation of clinically defined atrial cardiomyopathy stages and their association with atrial fibrillation burden under continuous monitoring for a 2.5-year follow-up. EP Europace, 28(7), Article euag146. https://doi.org/10.1093/europace/euag146
    • Al-Taie, C., Obergassel, J., Borof, K., Ridder, J., Rillig, A., Metzner, A., Goette, A., Magnussen, C., Sinner, M. F., Sommerfeld, L. C., Willems, S., Zeller, T., Schnabel, R. B., Schotten, U., Zapf, A., Kirchhof, P., & Fabritz, L. (2026). Interactions of blood biomolecules with early rhythm control in atrial fibrillation patients: exploratory analysis of the EAST-AFNET 4 biomolecule study. EP Europace, 28(7), Article euag149. https://doi.org/10.1093/europace/euag149
    • Ayagama, T., Barrett-Jolley, R., Fischer, R., Hester, S. S., Schotten, U., Verheule, S., & Burton, R. A. B. (2026). Proteomic signatures of mitochondrial dysfunction associated with atrial fibrillation in goats. Scientific Reports, 16(1), Article 28023. https://doi.org/10.1038/s41598-026-58413-1
    • Baron, D. K., Weberndorfer, V., Crijns, H. J. G. M., Hemels, M. E. W., Tieleman, R. G., de Melis, M., Schotten, U., Linz, D., Van Gelder, I. C., & Rienstra, M. (2026). Association between atherosclerosis and atrial fibrillation progression in patients with paroxysmal atrial fibrillation: Data from the RACE V study. American Heart Journal, 296, Article 107366. https://doi.org/10.1016/j.ahj.2026.107366
    • Baron, D. K., Samuel, M., Crijns, H. J. G. . M., Tieleman, R. G., Hemels, M. E. W., Schotten, U., Linz, D., Van Gelder, I. C., Rienstra, M., & RACE V Investigators (2026). Risk prediction of atrial fibrillation progression in patients with paroxysmal atrial fibrillation: data from the RACE V study. IJC Heart and Vasculature, 64, Article 101932. https://doi.org/10.1016/j.ijcha.2026.101932
    • Ismaili, D., Virtanen, P., Im, J., Brunnbauer, P., Saleem, U., Sonmez, M. I., Schulz, C., Nandudu, M., Winters, J., Molina, C. E., Petersen, J., Stoll, M., Schotten, U., Hansen, A., Eschenhagen, T., Koivumaki, J. T., & Christ, T. (2026). Higher sensitivity to ouabain-induced toxicity in human induced pluripotent stem cell-derived cardiomyocytes than human adult heart tissue despite similar Na<SUP>+</SUP>/K<SUP>+</SUP>-ATPase pump current amplitudes. British Journal of Pharmacology, 183(11), 3093-3110. https://doi.org/10.1111/bph.70380
    • Sandgren, E., Betz, K., Gawalko, M., Hermans, A., Habibi, Z., Verhaert, D., Philippens, S., Vorstermans, B., Kessels, M., Bovenkerk, D., Hermans, B. J. M., Hendriks, J. M., den Uijl, D., Chaldoupi, S.-M., Luermans, J., Lankveld, T., Schotten, U., Vernooy, K., & Linz, D. (2026). Symptom severity assessment in patients with atrial fibrillation after catheter ablation using a smartphone application. EP Europace, 28(6), Article euag139. https://doi.org/10.1093/europace/euag139
    • Goette, A., Lemoine, M. D., Fierenz, A., Bertaglia, E., Beuger, V., Blomstrom-Lundqvist, C., Brandes, A., Calvert, M., Camm, A. J., Chlouverakis, G., Dan, G.-A., Dichtl, W., Diener, H. C., de Groot, J. R., Kennes, L. N., Lip, G. Y. H., Lubinski, A., Marijon, E., Merkely, B., ... NOAH-AFNET 6 investigators (2026). Kidney disease increases the risk of cardiovascular events in patients with device-detected atrial fibrillation: NOAH-AFNET 6. EP Europace, 28(4), Article euag083. https://doi.org/10.1093/europace/euag083
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