Steven Meex

Clinical Chemist

Dr Steven Meex is a clinical chemist and head of the unit general clinical chemistry and hematology of the Central Diagnostic Laboratory of Maastrcith UMC+. He graduated in 2002 with specialisation in both molecular biology and epidemiology at Maastricht University. During his PhD at the Department of Internal Medicine in Maastricht, he worked on the cardiovascular genetics including type 2 diabetes and hyperlipidemia. Subsequently, he worked as acardiovascular research fellow at San Diego State University (2006) and at New York University (2008-2009).

His current research is focussed on cardiac markers,combining epidemiology, cell biology, analytical chemistry, and patient studies to improve the diagnosis and treatment of cardiovascular diseases.

Central Diagnostic Laboratory
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 5.E2.002
T: +31(0)43 387 47 09

  • 2025
    • Van Dam, P. M. E. L., Van Doorn, W. P. T. M., Sevenich, L., Lambriks, L., Cals, J. W. L., Bekers, O., Stassen, P. M., & Meex, S. J. R. (2025). Machine learning for risk stratification in the emergency department (MARS-ED): a randomized controlled trial. Nature Communications, 17(1), Article 242. https://doi.org/10.1038/s41467-025-66947-7
    • van Oeteren, M. A. J., De Groot, D. M., Buziau, A. M., Scheijen, J. L. J. M., van de Waarenburg, M. P. H., Kroon, A. A., Eussen, S. J. P. M., Dagnelie, P. C., Van Greevenbroek, M. M. J., Houben, A. J. H. M., Meex, S. J. R., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2025). The effects of dietary fructose on blood pressure are modified by the food matrix. Clinical Nutrition, 55, 134-140. https://doi.org/10.1016/j.clnu.2025.10.017
    • Weerts, J., Schroen, B. L. M., Barandiaran Aizpurua, A., Berendschot, T. T. J. M., Brandts, L., Webers, C. A. B., Simons, S. O., Meex, S. J. R., Henry, R., van der Kallen, C. J. H., Brunner-La Rocca, H.-P., Knackstedt, C., Heymans, S. R. B., de Boer, R. A., van Empel, V. P. M., & Houben, A. J. H. M. (2025). Microvascular dysfunction across organs in heart failure with preserved ejection fraction: the PROSE-HFpEF case-control study. Cardiovascular Diabetology, 24(1), Article 310. https://doi.org/10.1186/s12933-025-02850-1
    • Koene, E. J., Buziau, A. M., Cassiman, D., Cox, T. M., Bons, J., Scheijen, J. L. J. M., Schalkwijk, C. G., Meex, S. J., Saxena, A. R., Esler, W. P., Schrauwen-Hinderling, V. B., Schrauwen, P., & Brouwers, M. C. (2025). Safety and efficacy of pharmacological inhibition of ketohexokinase in hereditary fructose intolerance. Journal of Clinical Investigation, 135(6), Article e187376. https://doi.org/10.1172/JCI187376
    • Martens, R. J. H., van Doorn, W. P. T. M., Leers, M. P. G., Meex, S. J. R., & Helmich, F. (2025). Unraveling Uncertainty: The Impact of Biological and Analytical Variation on the Prediction Uncertainty of Categorical Prediction Models. Journal of Applied Laboratory Medicine, 10(2), 339-351. Article jfae115. https://doi.org/10.1093/jalm/jfae115
    • Meex, S. J. R., & Aakre, K. M. (2025). Personalized ranges for blood-test results enable precision diagnostics. Nature, 637(8045), 279-280. https://doi.org/10.1038/d41586-024-03854-9
  • 2024
    • Heyens, L., Kenjic, H., Dagnelie, P., Schalkwijk, C., Stehouwer, C., Meex, S., Kooman, J., Bekers, O., van Greevenbroek, M., Savelberg, H., Robaeys, G., de Galan, B., Koster, A., van Dongen, M., Eussen, S., & Koek, G. (2024). Forns index and fatty liver index, but not FIB-4, are associated with indices of glycaemia, pre-diabetes and type 2 diabetes: analysis of The Maastricht Study. BMJ Open Gastroenterology, 11(1), Article e001466. https://doi.org/10.1136/bmjgast-2024-001466
    • Ghossein, M. A., de Kok, J. W. T. M., Eerenberg, F., van Rosmalen, F., Boereboom, R., Duisberg, F., Verharen, K., Sels, J. E. M., Delnoij, T., Geyik, Z., Mingels, A. M. A., Meex, S. J. R., van Kuijk, S. M. J., van Stipdonk, A. M. W., Ghossein, C., Prinzen, F. W., van der Horst, I. C. C., Vernooy, K., van Bussel, B. C. T., & Driessen, R. G. H. (2024). Monitoring of myocardial injury by serial measurements of QRS area and T area: The MaastrICCht cohort. Annals of Noninvasive Electrocardiology, 29(5), Article e70001. https://doi.org/10.1111/anec.70001
    • van der Mee, F. A. M., Schaper, F., Jansen, J., Bons, J. A. P., Meex, S. J. R., & Cals, J. W. L. (2024). Enhancing Patient Understanding of Laboratory Test Results: Systematic Review of Presentation Formats and Their Impact on Perception, Decision, Action, and Memory. Journal of Medical Internet Research, 26, Article e53993. https://doi.org/10.2196/53993
    • Jaffe, A. S., Meex, S. J. R., Saenger, A. K., & van Wijk, X. M. R. (2024). A special series on cardiac troponin: An analytical and clinical matter. Journal of Laboratory and Precision Medicine, 9, Article 11. https://doi.org/10.21037/jlpm-24-29