Simone Eussen

Assistant Professor

Dr Simone Eussen's research focusses on the role of nutrition and underlying metabolic and molecular processes in the aetiology of common chronic diseases. She has built a strong track record on B-vitamins, related molecular one-carbon and kynurenine pathways, and chronic diseases during her PhD (Wageningen Universtiy) and post-doc (Bergen, Norway; also supported by a prestigious personal research grant from the Norwegian Research Council). She integrated this expertise to study quality of food intake at Maastricht University. Funds granted by the NWO (BBMRI) and the European JPI (Dedipac) focussed on methodological aspects of dietary assessment.

Her current work involves study of dietary quality (at nutrient and bioactive compound, food group, and dietary patterns level) in relation to chronic disease, including T2DM, CVD and mental disorders. Additionally, she expanded her focus to the emerging field of ‘chrono-nutrition’, and is member of the CIRCLE-DOME (CIRcadian CLock and timing of Eating on Diabetes, Obesity ad MEtabolism) network. Different aspects of dietary timing will be studied in relation to metabolic, cardiovascular and mental phenotypes to gain new insight in the role of chrono-nutrition in common pathologies within the framework of population based studies (for example The Maastricht Study; one of the world’s leading deep-phenotying population-based studies on T2DM and its comorbidities).

Department of Epidemiology
P. Debeyeplein 1, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: A2.018
T: +31(0)43 388 24 51

  • 2022
    • Geraets, A. F. J., Schram, M. T., Jansen, J. F. A., Backes, W. H., Schalkwijk, C. G., Stehouwer, C. D. A., van Boxtel, M. P. J., Eussen, S. J. P. M., Kooman, J. P., Verhey, F. R. J., & Köhler, S. (2022). The cardiometabolic depression subtype and its association with clinical characteristics: The Maastricht Study. Journal of Affective Disorders, 313, 110-117. https://doi.org/10.1016/j.jad.2022.06.045
    • Brouwers, M. C. G. J., Simons, N., Kooi, M. E., de Ritter, R., van Dongen, M. C. J. M., Eussen, S. J. P. M., Bekers, O., Kooman, J., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schram, M. T., Schaper, N. C., Schalkwijk, C. G., & Stehouwer, C. D. A. (2022). Intrahepatic lipid content is independently associated with soluble E-selectin levels: The Maastricht study. Digestive and Liver Disease, 54(8), 1038-1043. https://doi.org/10.1016/j.dld.2022.01.130
    • Clemmensen, K. K. B., Koster, A., Nielen, J. T. H., Dagnelie, P. C., Stehouwer, C. D. A., Bosma, H., Wesselius, A., Færch, K., & Eussen, S. J. P. M. (2022). Role of weekday variation on glucose, insulin, and triglyceride: A cross-sectional analysis from The Maastricht Study. Journal of Clinical Endocrinology & Metabolism, 107(8), E3145-E3151. https://doi.org/10.1210/clinem/dgac286
    • Linkens, A. M. A., van Best, N., Niessen, P. M., Wijckmans, N. E. G., de Goei, E. E. C., Scheijen, J. L. J. M., van Dongen, M. C. J. M., van Gool, C. C. J. A. W., de Vos, W. M., Houben, A. J. H. M., Stehouwer, C. D. A., Eussen, S. J. M. P., Penders, J., & Schalkwijk, C. G. (2022). A 4-Week Diet Low or High in Advanced Glycation Endproducts Has Limited Impact on Gut Microbial Composition in Abdominally Obese Individuals: The deAGEing Trial. International journal of molecular sciences, 23(10), [5328]. https://doi.org/10.3390/ijms23105328
    • Vandercappellen, E. J., Koster, A., Savelberg, H. H. C. M., Eussen, S. J. P. M., Dagnelie, P. C., Schaper, N. C., Schram, M. T., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Kroon, A. A., Henry, R. M. A., & Stehouwer, C. D. A. (2022). Sedentary behaviour and physical activity are associated with biomarkers of endothelial dysfunction and low-grade inflammation-relevance for (pre)diabetes: The Maastricht Study. Diabetologia, 65(5), 777-789. https://doi.org/10.1007/s00125-022-05651-3
    • Linkens, A. M. A., Houben, A. J., Niessen, P. M., Wijckmans, N., de Goei, E., Van den Eynde, M. D. G., Scheijen, J. L. J. M., Waarenburg, M., Mari, A., Berendschot, T. T. J. M., Streese, L., Hanssen, H., van Dongen, M. C. J. M., van Gool, C., Stehouwer, C. D. A., Eussen, S. J. P. M., & Schalkwijk, C. (2022). A 4-week high-AGE diet does not impair glucose metabolism and vascular function in obese individuals. JCI INSIGHT, 7(6), [156950]. https://doi.org/10.1172/jci.insight.156950
    • Linkens, A. M. A., Houben, A. J. H. M., Kroon, A. A., Schram, M. T., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M., Henry, R. M. A., de Galan, B., Stehouwer, C. D. A., Eussen, S. J. M. P., & Schalkwijk, C. G. (2022). Habitual intake of dietary advanced glycation end products is not associated with generalized microvascular function-the Maastricht Study. American Journal of Clinical Nutrition, 115(2), 444-455. https://doi.org/10.1093/ajcn/nqab302
    • Maasen, K., Eussen, S. J. P. M., Scheijen, J. L. J. M., van der Kallen, C. J. H., Dagnelie, P. C., Opperhuizen, A., Stehouwer, C. D. A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2022). Higher habitual intake of dietary dicarbonyls is associated with higher corresponding plasma dicarbonyl concentrations and skin autofluorescence: the Maastricht Study. American Journal of Clinical Nutrition, 115(1), 34-44. https://doi.org/10.1093/ajcn/nqab329
    • Obeid, R., Eussen, S. J. P. M., Mommers, M., Smits, L., & Thijs, C. (2022). Imbalanced Folate and Vitamin B12 in the Third Trimester of Pregnancy and its Association with Birthweight and Child Growth up to 2 Years. Molecular Nutrition & Food Research, 66(2), [2100662]. https://doi.org/10.1002/mnfr.202100662
  • 2021
    • van der Heide, F. C. T., Steens, I. L. M., Geraets, A. F. J., Foreman, Y. D., Henry, R. M. A., Kroon, A. A., van der Kallen, C. J. H., van Sloten, T. T., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Webers, C. A. B., van Greevenbroek, M. M. J., Wesselius, A., Koster, A., Schaper, N. C., Schram, M. T., ... Stehouwer, C. D. A. (2021). Association of Retinal Nerve Fiber Layer Thickness, an Index of Neurodegeneration, With Depressive Symptoms Over Time. Jama network open, 4(11), e2134753. [2134753]. https://doi.org/10.1001/jamanetworkopen.2021.34753