Simone Eussen

Assistant Professor

Dr Simone Eussen's research focusses on the role of nutrition and underlying metabolic and molecular processes in the aetiology of common chronic diseases. She has built a strong track record on B-vitamins, related molecular one-carbon and kynurenine pathways, and chronic diseases during her PhD (Wageningen Universtiy) and post-doc (Bergen, Norway; also supported by a prestigious personal research grant from the Norwegian Research Council). She integrated this expertise to study quality of food intake at Maastricht University. Funds granted by the NWO (BBMRI) and the European JPI (Dedipac) focussed on methodological aspects of dietary assessment.

Her current work involves study of dietary quality (at nutrient and bioactive compound, food group, and dietary patterns level) in relation to chronic disease, including T2DM, CVD and mental disorders. Additionally, she expanded her focus to the emerging field of ‘chrono-nutrition’, and is member of the CIRCLE-DOME (CIRcadian CLock and timing of Eating on Diabetes, Obesity ad MEtabolism) network. Different aspects of dietary timing will be studied in relation to metabolic, cardiovascular and mental phenotypes to gain new insight in the role of chrono-nutrition in common pathologies within the framework of population based studies (for example The Maastricht Study; one of the world’s leading deep-phenotying population-based studies on T2DM and its comorbidities).

Department of Epidemiology
P. Debeyeplein 1, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: A2.018
T: +31(0)43 388 24 51

  • 2022
    • Gulpers, B. J. A., Verhey, F. R. J., Eussen, S. J. P. M., Schram, M. T., de Galan, B. E., van Boxtel, M. P. J., Stehouwer, C. D. A., & Köhler, S. (2022). Anxiety and cognitive functioning in the Maastricht study: A cross-sectional population study. Journal of Affective Disorders, 319, 570-579. https://doi.org/10.1016/j.jad.2022.09.072
    • Holthuijsen, D. D. B., Bours, M. J. L., Roekel, E. H. V., Breukink, S. O., Janssen-Heijnen, M. L. G., Keulen, E. T. P., Ueland, P. M., Midttun, Ø., Brezina, S., Gigic, B., Gsur, A., Kok, D. E., Ose, J., Ulrich, C. M., Weijenberg, M. P., & Eussen, S. J. P. M. (2022). Longitudinal Associations of Adherence to the Dietary World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) and Dutch Healthy Diet (DHD) Recommendations with Plasma Kynurenines in Colorectal Cancer Survivors after Treatment. Nutrients, 14(23), [5151]. https://doi.org/10.3390/nu14235151
    • Gianfredi, V., Schaper, N. C., Odone, A., Signorelli, C., Amerio, A., Eussen, S. J. P. M., Köhler, S., Savelberg, H. H. C. M., Stehouwer, C. D. A., Dagnelie, P. C., Henry, R. M. A., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Schram, M. T., & Koster, A. (2022). Daily patterns of physical activity, sedentary behavior, and prevalent and incident depression-The Maastricht Study. Scandinavian Journal of Medicine & Science in Sports, 32(12), 1768-1780. https://doi.org/10.1111/sms.14235
    • Yu, E. Y-W., Ren, Z., Mehrkanoon, S., Stehouwer, C. D. A., van Greevenbroek, M. M. J., Eussen, S. J. P. M., Zeegers, M. P., & Wesselius, A. (2022). Plasma metabolomic profiling of dietary patterns associated with glucose metabolism status: The Maastricht Study. BMC Medicine, 20(1), 450. https://doi.org/10.1186/s12916-022-02653-1
    • van der Heide, F. C. T., Foreman, Y. D., Franken, I. W. M., Henry, R. M. A., Kroon, A. A., Dagnelie, P. C., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Webers, C. A. B., Schram, M. T., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Schaper, N. C., Brouwers, M. C. G. J., & Stehouwer, C. D. A. (2022). (Pre)diabetes, glycemia, and daily glucose variability are associated with retinal nerve fiber layer thickness in The Maastricht Study. Scientific Reports, 12(1), [17750]. https://doi.org/10.1038/s41598-022-22748-2
    • Konopka, M. J., Kohler, S., Stehouwer, C. D. A., Schaper, N. C., Henry, R. M. A., van der Kallen, C. J. H., Savelberg, H. H. C. M., Eussen, S. J. P. M., Dagniele, P. C., van Dongen, M. C. J. M., Schram, M. T., & Koster, A. (2022). Accelerometer-derived sedentary time and physical activity and the incidence of depressive symptoms - The Maastricht Study. Psychological Medicine, 52(13), 2786-2793. https://doi.org/10.1017/S0033291720004924
    • Sun, C., van Soest, J., Koster, A., Eussen, S. J. P. M., Schram, M. T., Stehouwer, C. D. A., Dagnelie, P. C., & Dumontier, M. (2022). Studying the association of diabetes and healthcare cost on distributed data from the Maastricht Study and Statistics Netherlands using a privacy-preserving federated learning infrastructure. Journal of Biomedical Informatics, 134. https://doi.org/10.1016/j.jbi.2022.104194
    • Geraets, A. F. J., Schram, M. T., Jansen, J. F. A., Backes, W. H., Schalkwijk, C. G., Stehouwer, C. D. A., van Boxtel, M. P. J., Eussen, S. J. P. M., Kooman, J. P., Verhey, F. R. J., & Köhler, S. (2022). The cardiometabolic depression subtype and its association with clinical characteristics: The Maastricht Study. Journal of Affective Disorders, 313, 110-117. https://doi.org/10.1016/j.jad.2022.06.045
    • Maasen, K., Eussen, S. J. P. M., Dagnelie, P. C., Houben, A. J. H. M., Webers, C. A. B., Schram, M. T., Berendschot, T. T. J. M., Stehouwer, C. D. A., Opperhuizen, A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2022). Habitual intake of dietary methylglyoxal is associated with less low-grade inflammation: the Maastricht Study. American Journal of Clinical Nutrition, 116(6), 1715-1728. https://doi.org/10.1093/ajcn/nqac195
    • Brouwers, M. C. G. J., Simons, N., Kooi, M. E., de Ritter, R., van Dongen, M. C. J. M., Eussen, S. J. P. M., Bekers, O., Kooman, J., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schram, M. T., Schaper, N. C., Schalkwijk, C. G., & Stehouwer, C. D. A. (2022). Intrahepatic lipid content is independently associated with soluble E-selectin levels: The Maastricht study. Digestive and Liver Disease, 54(8), 1038-1043. https://doi.org/10.1016/j.dld.2022.01.130