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Uyên Châu Nguyên wins UM Dissertation Prize 2025

Uyên Châu Nguyên wins UM Dissertation Prize 2025

29 January 2026

During the Dies Natalis of Maastricht University, Uyên Châu Nguyên received the UM Dissertation Prize 2025.

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Global research network launched to study menopause and heart health

Global research network launched to study menopause and heart health

20 January 2026

Ten international health research funders, including the Dutch Heart Foundation, are investing $10 million in a new global research network to improve early prevention of cardiovascular disease in women. The initiative focuses on understanding how menopause affects heart health and how early intervention can reduce risk.

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Carim Maastricht
Carim Maastricht

Rory Koenen

Professor

Dr Rory  Koenen studied biochemistry in Sittard (BSc) and at the Radboud University in Nijmegen (MSc), the Netherlands from 1993-1999. He completed his PhD in cardiovascular sciences at CARIM Maastricht University in 2005. He then worked in Germany at IMCAR, RWTH Aachen University until 2010 and then moved to IPEK at the LMU in Munich chaired by Christian Weber. In 2012, he returned to CARIM as the recipient of a Vidi grant.

Dr Koenen is currently investigating the functions of platelets beyond hemostasis, platelet microvesicles and the role of particular inflammatory molecules in vascular disease e.g. thrombosis and atherosclerosis. For example, he aims to characterise the molecular aspects of chemokine RANTES and platelet factor 4 secretion from platelets and its importance in the development of cardiovascular diseases. In addition, Dr Koenen is interested in the role of cell adhesion molecules in platelet function and in how platelets maintain interactions with other cell types (leukocytes, endothelial and smooth muscle cells). Finally, Dr Koenen investigates how platelets and their microvesicles can influence the behavior and phenotype of these cells.

As of 1 March 2023, Prof. Koenen holds a professorship of Vascular Inflammation and Thrombosis.

Rory-koenen

Department of Biochemistry
Universiteitsingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: 4.366a
T: +31(0)43 388 33 90

  • 2025
    • Xin, X., Dijkgraaf, I., Hackeng, T. M., & Koenen, R. R. (2025). Generation and characterization of platelet-derived extracellular vesicle analogues from lyophilized platelets. Extracellular Vesicle, 6, Article 100095. https://doi.org/10.1016/j.vesic.2025.100095
    • Liberale, L., Tual-Chalot, S., Sedej, S., Ministrini, S., Georgiopoulos, G., Grunewald, M., Back, M., Bochaton-Piallat, M.-L., Boon, R. A., Ramos, G. C., de Winther, M. P. J., Drosatos, K., Evans, P. C., Ferguson, J. F., Forslund-Startceva, S. K., Goettsch, C., Giacca, M., Haendeler, J., Kallikourdis, M., ... Et al. (2025). Roadmap for alleviating the manifestations of ageing in the cardiovascular system. Nature Reviews Cardiology, 22(8), 577-605. Article e131092. https://doi.org/10.1038/s41569-025-01130-5
    • Ganizada, B. H., Reesink, K. D., Parikh, S., Saraber, P. J. M. H., Cleutjens, J. P., Isabella, A., Krebbekx, M. Q. E., Jaminon, A. M., Maassen, C. F. M., Ramaekers, M. J. F. G., Spronck, B., van der Laan, K., Koenen, R. R., Lorusso, R., Maessen, J. G., Bidar, E., & Schurgers, L. J. (2025). Loss of wall stress homeostasis in ascending thoracic aortic aneurysm: histomorphometric insights into patient variants. The Journal of Physiology, 603(14), 3899-3922. https://doi.org/10.1113/JP288734
    • Nagy, M., Bender, M., Poulter, N. S., Pike, J. A., Sickmann, A., Vondenhoff, S., Bielicka, N., van Zandvoort, M. A. M. J., Koenen, R. R., ten Cate, H., Stéphenne, X., Heemskerk, J. W. M., & Baaten, C. C. F. M. J. (2025). Formation of tight junction-like structures of zonula occludens 2 in platelet–platelet interaction. Research and practice in thrombosis and haemostasis, 9(3), Article 102845. https://doi.org/10.1016/j.rpth.2025.102845
    • Bouwens, B. R. C., Magdeleyns, E., Thomassen, M. C. L. G. D., Bouwman, F. G., Suylen, D. P., Hackeng, T. M., & Koenen, R. R. (2025). Citrullination of tissue factor pathway inhibitor alpha by peptidylarginine deiminase 4 impairs its natural anticoagulant activity toward factors Xa and VIIa/tissue factor and reduces binding to its cofactor protein S. Journal of Thrombosis and Haemostasis, 23(2), 641-650. https://doi.org/10.1016/j.jtha.2024.11.009
    • Koenen, R. R. (2025). TH Open-Editor's Highlights of 2024. TH open : companion journal to thrombosis and haemostasis, 09, Article a25134445. https://doi.org/10.1055/a-2513-4445
    • Xin, X., & Koenen, R. R. (2025). Assessing platelet-derived extracellular vesicles for potential as therapeutic targets in cardiovascular diseases. Expert Opinion on Therapeutic Targets, 29(1-2), 17-28. https://doi.org/10.1080/14728222.2025.2454617
  • 2024
    • Lemmens, T. P., Luo, Q., Wielders, S. J. H., Scheijen, J. L. J. M., Al-Nasiry, S., Koenen, R. R., Wenzel, P., & Cosemans, J. M. E. M. (2024). Platelet collagen receptors and their role in modulating platelet adhesion patterns and activation on alternatively processed collagen substrates. Thrombosis Research, 244, Article 109201. https://doi.org/10.1016/j.thromres.2024.109201
    • Rigby, A., Albisetti, M., Favaloro, E. J., Koenen, R. R., Langer, F., Lip, G. Y. H., Ruehl, H., & Weber, C. (2024). Reflections on World Thrombosis Day 2024. Thrombosis and Haemostasis, 125(1), 3-6. https://doi.org/10.1055/s-0044-1791650
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