Miranda Schram

Professor

Dr Miranda Schram holds a MSc in Biomedical Sciences (1999) and in Epidemiology (2002). She recieved her PhD entitled 'Patophysiology of diabetic complications, arterial stiffness, endothelial dysfunction and inflammation' at VU University Medical Center in Amsterdam in 2004, and is a registered Epidemiologist B. She has worked as post-doc epidemiologist at Erasmus MC in Rotterdam, at Leiden University Medical Center and as senior investigator at the National Institute for Public Health and the Environment in Bilthoven. From 2008 onwards, she has been working at Maastricht UMC+ as senior investigator at The Maastricht Study.

Miranda Schram is one of the founders of The Maastricht Study, a novel population-based cohort study on type 2 diabetes and its complications. Her scientific work focusses on the etiology and epidemiology of cognitive decline and depression in type 2 diabetes with a specific interest in the role of early vascular dysfunction. A second research line focusses on psychosocial aspects of diabetes, to understand how social networks, but also ethnicity and diabetes distress can affect diabetes treatment and the development of complications. Miranda is board member of The Maastricht Study, coordinator of the Dutch Diabetes Pearlstring Initiative, active member of the PSAD study group of the EASD and involved in the Netherlands Consortium of Demetia Cohorts.

Department of Internal Medicine
Randwycksingel 35, 6229 EG Maastricht
T: +31(0)6 122 64 289

2024
- van Gennip, A. C. E., Gupta, M. D., Houben, A. J. H. M., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Koster, A., Wesselius, A., Eussen, S. J. P. M., Schalkwijk, C. G., de Galan, B. E., Köhler, S., Schram, M. T., Stehouwer, C. D. A., & van Sloten, T. T. (2024). Retinal microvascular function and incidence and trajectories of clinically relevant depressive symptoms: the Maastricht Study. Psychological Medicine, 1-10. Advance online publication. https://doi.org/10.1017/S0033291724000618
- Beran, M., van Gennip, A. C. E., Stehouwer, C. D. A., Jansen, J. F. A., Gupta, M. D., Houben, A. J. H. M., Berendschot, T. T. J. M., Webers, C. A. B., Wesselius, A., Schalkwijk, C. G., Backes, W. H., de Jong, J. J. A., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Köhler, S., Vonk, J. M. J., Geerlings, M. I., Schram, M. T., & van Sloten, T. T. (2024). Microvascular Dysfunction and Whole-Brain White Matter Connectivity: The Maastricht Study. Journal of the American Heart Association, 13(3), Article e9112. https://doi.org/10.1161/JAHA.123.031573
- Monereo-Sánchez, J., Jansen, J. F. A., van Boxtel, M. P. J., Backes, W. H., Köhler, S., Stehouwer, C. D. A., Linden, D. E. J., & Schram, M. T. (2024). Association of hippocampal subfield volumes with prevalence, course and incidence of depressive symptoms: The Maastricht Study. British Journal of Psychiatry, 224(2), 66-73. https://doi.org/10.1192/bjp.2023.143
- de Jong, J. J. A., Jansen, J. F. A., Vergoossen, L. W. M., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., Linden, D. E. J., & Backes, W. H. (2024). Effect of Magnetic Resonance Image Quality on Structural and Functional Brain Connectivity: The Maastricht Study. Brain Sciences, 14(1). https://doi.org/10.3390/brainsci14010062
- van der Heide, F. C. T., Steens, I. L. M., Limmen, B., Mokhtar, S., van Boxtel, M. P. J., Schram, M. T., Köhler, S., Kroon, A. A., van der Kallen, C. J. H., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M. M. J., Koster, A., van Sloten, T. T., Jansen, J. F. A., Backes, W. H., & Stehouwer, C. D. A. (2024). Thinner inner retinal layers are associated with lower cognitive performance, lower brain volume, and altered white matter network structure-The Maastricht Study. Alzheimer's & Dementia, 20(1), 316-329. https://doi.org/10.1002/alz.13442
- Schmitt, A., Beran, M., Geraets, A., Iversen, M. M., Nefs, G., Nouwen, A., Pouwer, F., Huber, J. W., & Schram, M. T. (2024). Associations between HbA1c reduction and change in depressive symptoms following glucose-lowering treatment in adults: A systematic review of intervention studies. Current Diabetes Reviews, 20(3), 66-83. Article e020623217607. https://doi.org/10.2174/1573399820666230602124223
- van der Heide, F. C. T., Khawaja, A., Berendschot, T. T. J. M., Littlejohns, T. J., Kuźma, E., Luben, R., Patel, P. J., Foster, P. J., Webers, C., Kroon, B., van der Kallen, C., van Dongen, M., Eussen, S., Schalkwijk, C., Bosma, H., Koehler, S., Schram, M., Blokland, G., Linden, D., ... Stehouwer, C. D. A. (2024). Associations of inner retinal layers with risk of incident dementia: An individual participant data analysis of four prospective cohort studies. Alzheimer's & Dementia, 20(1), 211-220. Article 13167. https://doi.org/10.1002/alz.13167
- Meisters, R., Albers, J., Sezer, B., de Galan, B. E., Eussen, S. J. P. M., Stehouwer, C. D. A., Schram, M. T., van Greevenbroek, M. M. J., Wesselius, A., Koster, A., & Bosma, H. (2024). Socioeconomic inequalities in health-related functioning among people with type 2 Diabetes: longitudinal analyses in the Maastricht Study. BMC Public Health, 24(1), Article 73. https://doi.org/10.1186/s12889-023-17553-z
2023
- Truin, L. S., Kohler, S., Heger, I. S., van Boxtel, M. P. J., Schram, M. T., Backes, W. H., Jansen, J. F. A., van Dongen, M. M. C. J. M., de Vries, N. K., de Vries, H., Eussen, S. J. P. M., Stehouwer, C. D. A., de Vugt, M. E., & Deckers, K. (2023). Associations of an individual's need for cognition with structural brain damage and cognitive functioning/impairment: cross-sectional population-based study. British Journal of Psychiatry, 1-9. https://doi.org/10.1192/bjp.2023.159

Overview

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Professorship Julie Staals

22 April 2024

ERC Advanced Grant awarded to Prof. Andy Baker

15 April 2024

Miranda Schram

Professor