Martina Calore

Assistant Professor

Dr Martina Calore has graduated in Biotechnology with specialisation in Human Genetics at Padova University. Subsequently, she obtained her PhD in Cardiovascular Sciences in Padova. During these years, she acquired a wide experience on genetic analyses performed both with traditional methods and with next generation sequencing (NGS) and on the interpretation of the variants detected in patients affected with inherited cardiomyopathies. She also focussed on the identification of novel genes involved in arrhythmogenic cardiomyopathy (ACM) by coupling genetic and functional studies. After her PhD, she collaborated with BMR genomics (Padova, Italy) in a project aimed at developing a technical and analytical strategy to analyze by NGS a panel of genes involved in different cardiomyopathies. In 2015, thanks to a Marie Sklodowska-Curie fellowship, she started working in the Department of Cardiology of Maastricht University under the supervision of Prof. Leon de Windt in order to investigate the role of microRNAs in the pathogenesis of ACM.

Since 2018, she has been Assistant Professor at Maastricht University. Her research is focussed on the generation of novel in vivo and in vitro models for ACM in order to study the pathogenic mechanisms of the disease and to develop novel therapeutic strategies. She supervises PhD students and is involved in teaching in the courses of Genetics and Molecular Biology at Maastricht Science Program and Human Genetics, Reproduction and Prenatal Development at the Faculty of Health, Medicine and Life Sciences.

Department of Cardiology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: G3.234
T: +31(0)43 388 43 01

  • 2021
    • Sacchetto, C., Mohseni, Z., Colpaert, R. M. W., Vitiello, L., De Bortoli, M., Vonhogen, I. G. C., Xiao, K., Poloni, G., Lorenzon, A., Romualdi, C., Bariani, R., Mazzotti, E., Daliento, L., Bauce, B., Corrado, D., Thum, T., Rampazzo, A., de Windt, L. J., & Calore, M. (2021). Circulating miR-185-5p as a Potential Biomarker for Arrhythmogenic Right Ventricular Cardiomyopathy. Cells, 10(10), Article 2578.
    • Schreurs, J., Sacchetto, C., Colpaert, R. M. W., Vitiello, L., Rampazzo, A., & Calore, M. (2021). Recent Advances in CRISPR/Cas9-Based Genome Editing Tools for Cardiac Diseases. International Journal of Molecular Sciences, 22(20), Article 10985.
    • Colpaert, R. M. W., & Calore, M. (2021). Epigenetics and microRNAs in cardiovascular diseases. Genomics, 113(2), 540-551.
  • 2020
    • Vonhogen, I. G. C., Mohseni, Z., Winkens, B., Xiao, K., Thum, T., Calore, M., Martins, P. A. D. C., de Windt, L. J., Spaanderman, M. E. A., & Ghossein-Doha, C. (2020). Circulating miR-216a as a biomarker of metabolic alterations and obesity in women. Non-Coding rna research, 5(3), 144-152.
    • Sacchetto, C., Vitiello, L., de Windt, L. J., Rampazzo, A., & Calore, M. (2020). Modeling Cardiovascular Diseases with hiPSC-Derived Cardiomyocytes in 2D and 3D Cultures. International Journal of Molecular Sciences, 21(9), Article 3404.
    • De Bortoli, M., Vio, R., Basso, C., Calore, M., Minervini, G., Angelini, A., Melacini, P., Vitiello, L., Vazza, G., Thiene, G., Tosatto, S., Corrado, D., Iliceto, S., Rampazzo, A., & Calore, C. (2020). Novel Missense Variant in MYL2 Gene Associated With Hypertrophic Cardiomyopathy Showing High Incidence of Restrictive Physiology. Circulation: Genomic and Precision Medicine, 13(2), Article 002824.
  • 2019
    • Sacchetto, C., Sequeira, V., Bertero, E., Dudek, J., Maack, C., & Calore, M. (2019). Metabolic Alterations in Inherited Cardiomyopathies. Journal of Clinical Medicine, 8(12), Article 2195.
    • Calore, M., Poloni, G., Postma, A. V., Lorenzon, A., Minervini, G., Vazza, G., Li Mura, I. E. A., Telatin, A., Zara, I., Simionati, B., Ponti, J., Occhi, G., Vitiello, L., Bauce, B., Tosatto, S. C. E., van Tintelen, P. J., Rampazzo, A., & De Bortoli, M. (2019). Next Generation Sequencing identifies novel variants in TJP1, TP63 and PPP1R13L genes in Arrhythmogenic Cardiomyopathy patients. European Journal of Human Genetics, 27, 1304-1305.
    • Calore, M., Lorenzon, A., Vitiello, L., Poloni, G., Beffagna, G., Dazzo, E., Polishchuk, R., Sabatelli, P., Doliana, R., Carnevale, D., Lembo, G., Bonaldo, P., de Windt, L. J., Braghetta, P., & Rampazzo, A. (2019). A novel murine model for arrhythmogenic cardiomyopathy points to a pathogenic role of Wnt/b-catenin signaling and miRNA dysregulation. European Journal of Human Genetics, 27, 842-842.
    • Colpaert, R. M. W., & Calore, M. (2019). MicroRNAs in Cardiac Diseases. Cells, 8(7), Article 737.