Julie Staals

Professor

Dr Julie Staals is working as a clinical neurologist at Maastricht UMC+. Her specialisation is neurovascular diseases. She has obtained her medical degree at Maastricht University. Afterwards, she did a parallel tract in neurology training and PhD research project, both were finished in 2009. In 2013 she did a short research fellowship at the Brain Research Imaging Center in Edinburgh, UK. Her research focus is on clinical studies in cerebral small vessel disease, mainly the effects of hypertension, the rol of endothelial function, blood-brain barrier and the neurovascular unit, advanced imaging, and the cognitive consequences of this disease. She developed the ‘total SVD score’, a highly cited score for MRI severity of cerebral small vessel disease. Other clinical research topics are intracerebral haemorrhage and acute stroke treatments.

She is currently involved in:
SVDs@target, a EU Horizon2020 multicenter project on mechanisms in cerebral small vessel disease (www.svds-at-target.eu)

CRUCIAL, a EU Horizon2020 multicenter project on microvascular rarefaction in vascular cognitive impairment and heart failure (www.crucial-project.eu)

MRCLEAN trials, acute clinical stroke trials aiming at improving outcome in endovascular treatment (www.contrast-consortium.nl)

Department of Neurology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

2024
- Prats-Sanchez, L., Camps-Renom, P., Nash, P. S., Wilson, D., Ambler, G., Best, J. G., Guasch-Jiménez, M., Ramos-Pachón, A., Martinez-Domeño, A., Lambea-Gil, Á., Díaz, G. E., Guisado-Alonso, D., Du, H., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y., Ay, H., Jung, S., Bornstein, N. M., ... Microbleeds International Collaborative Network (MICON) (2024). Statin Therapy for Secondary Prevention in Ischemic Stroke Patients With Cerebral Microbleeds. Neurology, 102(7), Article 209173. https://doi.org/10.1212/WNL.0000000000209173
- van Voorst, H., Hoving, J. W., Koopman, M. S., Daems, J. D., Peerlings, D., Buskens, E., Lingsma, H. F., Beenen, L. F. M., de Jong, H. W. A. M., Berkhemer, O. A., van Zwam, W. H., Roos, Y. B. W. E. M., van Walderveen, M. A. A., van den Wijngaard, I., Dippel, D. W. J., Yoo, A. J., Campbell, B. C. V., Kunz, W. G., Emmer, B. J., ... MR CLEAN Registry Investigators (2024). Cost-effectiveness of CT perfusion for the detection of large vessel occlusion acute ischemic stroke followed by endovascular treatment: a model-based health economic evaluation study. European Radiology, 34(4), 2152-2167. https://doi.org/10.1007/s00330-023-10119-y
- Oestreich, L. K., Lo, J. W., Di Biase, M. A., Sachdev, P. S., Mok, A. H., Wright, P., Crawford, J. D., Lam, B., Traykov, L., Köhler, S., Staals, J. E., van Oostenbrugge, R., Chen, C., Desmond, D. W., Yu, K.-H., Lee, M., Klimkowicz-Mrowiec, A., Bordet, R., O'Sullivan, M. J., & Zalesky, A. (2024). Network analysis of neuropsychiatric, cognitive, and functional complications of stroke: implications for novel treatment targets. Psychiatry and Clinical Neurosciences, 78(4), 229-236. https://doi.org/10.1111/pcn.13633
- Robbe, M. M. Q., Pinckaers, F. M. E., Olthuis, S. G. H., Bos, M. J., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Procedural Blood Pressure and Intracranial Hemorrhage on Dual-Energy Computed Tomography After Endovascular Stroke Treatment. Cardiovascular and Interventional Radiology, 47(4), 483-491. https://doi.org/10.1007/s00270-023-03619-3
- Senff, J. R., Singh, S. D., Pasi, M., Jolink, W. M. T., Rodrigues, M. A., Schreuder, F. H. B. M., Staals, J., Schreuder, T., Douwes, J. P. J., Talsma, J., McKaig, B. N., Kourkoulis, C., Yechoor, N., Anderson, C. D., Puy, L., Cordonnier, C., Wermer, M. J. H., Rothwell, P. M., Rosand, J., ... Brouwers, H. B. (2024). Long-Term Outcomes in Patients With Spontaneous Cerebellar Hemorrhage: An International Cohort Study. Stroke. Advance online publication. https://doi.org/10.1161/STROKEAHA.123.044622
- Robbe, M. M. Q., Pinckaers, F. M. E., Santegoeds, R. G. C., Bos, M. J., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Procedural blood pressure and contrast extravasation on dual energy computed tomography after endovascular stroke treatment. Journal of Stroke & Cerebrovascular Diseases, 33(6), Article 107673. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107673
- Hoving, J. W., Konduri, P. R., Tolhuisen, M. L., Koopman, M. S., van Voorst, H., Van Poppel, L. M., Daems, J. D., van Es, A. C. G. M., van Walderveen, M. A. A., Lingsma, H. F., Dippel, D. W. J., Van Zwam, W. H., Marquering, H. A., Majoie, C. B. L. M., Emmer, B. J., MR CLEAN Registry Investigators, van Oostenbrugge, R. J., Goldhoorn, R.-J., Hinsenveld, W., ... Pinckaers, F. (2024). Impact of Intracranial Volume and Brain Volume on the Prognostic Value of Computed Tomography Perfusion Core Volume in Acute Ischemic Stroke. Journal of Cardiovascular Development and Disease, 11(3), Article 80. https://doi.org/10.3390/jcdd11030080
- Wardlaw, J. M., Chabriat, H., de Leeuw, F.-E., Debette, S., Dichgans, M., Doubal, F., Jokinen, H., Katsanos, A. H., Ornello, R., Pantoni, L., Pasi, M., Pavlovic, A. M., Rudilosso, S., Schmidt, R., Staals, J., Taylor-Rowan, M., Hussain, S., & Lindgren, A. G. (2024). European stroke organisation (ESO) guideline on cerebral small vessel disease, part 2, lacunar ischaemic stroke. European Stroke Journal, 9(1), Article 23969873231219416. Advance online publication. https://doi.org/10.1177/23969873231219416
- Voorter, P. H. M., van Dinther, M., Jansen, W. J., Postma, A. A., Staals, J., Jansen, J. F. A., van Oostenbrugge, R. J., van der Thiel, M. M., & Backes, W. H. (2024). Blood-Brain Barrier Disruption and Perivascular Spaces in Small Vessel Disease and Neurodegenerative Diseases: A Review on MRI Methods and Insights. Journal of Magnetic Resonance Imaging, 59(2), 397-411. Article jmri28989. https://doi.org/10.1002/jmri.28989
- Knapen, R. R. M. M., Pirson, F. A. V., Langezaal, L. C. M., Brouwer, J., Majoie, C. B. L. M., Emmer, B. J., Vos, J.-A., van Doormaal, P.-J., Yoo, A. J., Bruggeman, A. A. E., Lycklama À Nijeholt, G. J., van der Leij, C., van Oostenbrugge, R. J., van Zwam, W. H., Schonewille, W. J., MR CLEAN Registry Investigators, Goldhoorn, R.-J., Hinsenveld, W., Staals, J., ... Pirson, A.-F. (2024). Intravenous Thrombolysis Before Endovascular Treatment in Posterior Circulation Occlusions: A MR CLEAN Registry Study. Stroke, 55(2), 403-412. https://doi.org/10.1161/STROKEAHA.123.043777

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Julie Staals

Professor