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Catheter treatment is not only effective, but also cost-effective for ischemic stroke

Catheter treatment is not only effective, but also cost-effective for ischemic stroke

29 September 2026

With ischemic stroke, every minute counts. However, many patients do not seek hospital care until it is too late, for example, because symptoms are not immediately recognized or because people wake up with signs of neurological deficits. As a result, a group of patients is no longer eligible for catheter treatment. 

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Platelets: more than a band-aid

Platelets: more than a band-aid

23 September 2026

Some processes in our body might seem obvious to us. If you cut your finger, the bleeding will stop shortly and form a scab. Behind that seemingly simple process hides a sophisticated system of platelets and clotting factors. By now, we know that platelets do much more than halt bleeding: they function as information carriers and regulators of disease processes. 

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Carim Maastricht
Carim Maastricht

Job Verdonschot

Assistant Professor

Dr. Job Verdonschot is a resident at the Clinical Genetics department of the Maastricht UMC+ and an assistant professor at the Cardiology department within CARIM of the Maastricht University.

He finished both a master in biomedical sciences and medicine (cum laude) at the university of Maastricht, with a differentiation in cardiogenetics. In 2016 he received a Kootstra Talent Fellowship to start a PhD investigating the impact of genetic mutations on the clinical course of patients with dilated cardiomyopathy. His PhD thesis received three prizes for best thesis of 2021: by the Dutch association of clinical genetics (VKGN), the Durch association of cardiology (NVVC) and the CARIM research school of the university of Maastricht. In 2021 he started his clinical training to become a clinical geneticist in the Maastricht UMC+ with a differentiation in cardiology and cardiogenetics, which he will finish in 2025, continuing his career as clinical geneticist at the department.

In 2022 he received the prestigious Dekker grant (Clinical Scientist) from the Dutch Heart Foundation to start his research group investigating the impact of genetic mutations for asymptomatic family members. In 2023 and 2024 he also received the Academic Funds and a Veni grant of the NWO to further expand his research line focusing on early detection, improving risk stratification and early treatment, and reproductive options for patients and their family members with a genetic form of dilated cardiomyopathy.

He contributes to multiple national and international committees (for example, he is chair of the national Study Group on family care for cardiomyopathy patients of the National Heart Institute, and leads the writing of international consensus documents on family care and reproductive options from the European Society of Cardiology). He has a strong focus on interdisciplinary collaborations to achieve innovation in health care, depicted by collaboration with the Dutch Forensic Institute (NOFA study funded by ZonMW), the technical University of Eindhoven (as part of the Veni project) and hematology (focusing on clonal hematopoiesis as part of his ERA4HEALTH grant). His goal is to translate research innovations to clinical implementation to improve the care for patients and family members with genetic forms of dilated cardiomyopathy.

Job verdonschot

Department of Cardiology 
Universiteitssingel 50, 6229 ER, Maastricht
P.O. Box 616, 6200 MD Maastricht

Room number: 3.K1.031
T: +31 (0) 43 387 10 98

  • 2026
    • Zwetsloot, P.-P., Henkens, M. T. H. M., van Iperen, E. P. A., Minten, M., van der Schaaf-de Wolf, E., van Laake, L. W., te Riele, A. S. J. M., van der Harst, P., van Setten, J., van Empel, V. P. M., Brunner-La Rocca, H.-P., Verdonschot, D. J. A. J., Cox, M. G. P. J., Christiaans, I., Ajmone Marsan, N., van Spaendonck-Zwarts, K., Barge-Schaapveld, D. Q. C. M., Cramer, E., Hoedemakers, Y. M., ... DCR Investigators (2026). The Dutch cardiomyopathy registry (DCR); rationale and registry design. Netherlands Heart Journal, 34(9), 288-298. https://doi.org/10.1007/s12471-026-02063-5
    • Liu, C.-H., Martens, D. S., An, D.-W., Siwy, J., Latosinska, A., Pellicori, P., Verdonschot, J. A. J., Ahmed, F. Z., Wei, F.-F., Rossignol, P., Petutschnigg, J., Heymans, S., Cuthbert, J. J., Yu, Y.-L., Girerd, N., Clark, A. L., Verhamme, P., Zhang, D.-Y., Li, Y., ... HOMAGE investigators (2026). Urinary proteomic signature of exercise intolerance in patients at risk of heart failure: evidence from the HOMAGE trial. EBioMedicine, 130, Article 106406. https://doi.org/10.1016/j.ebiom.2026.106406
    • Nihant, B. S. C., Verdonschot, J. A. J., Bălan, S., Thielecke, E., Luiken, J. J. F. P., Nabben, M., Heymans, S., Breuer, M., & Adriaens, M. E. (2026). Metabolic Task Analysis Reveals Distinct Metabotypes in End-Stage Dilated Cardiomyopathy. Circulation: Genomic and Precision Medicine, 19(4), e005366. Article e005366. https://doi.org/10.1161/CIRCGEN.125.005366
    • Stroeks, S. L. V. M., Bart, N. K., Rossano, J., Claggett, B., Beelen, N. J., Buchan, R. J., Day, S., Fornaro, A., Halliday, B. P., Wheeler, M. T., Hammersley, D. J., Helms, A., Heymans, A. B. M., Ho, C. Y., Khan, S. S., Lin, K., Lota, A., Merlo, M., Mestroni, L., ... DCM/ACM SHaRe Investigators (2026). Sex and Age Specific Genetic Risk Across the Dilated and Arrhythmogenic Cardiomyopathy Spectrum. Journal of the American College of Cardiology, 87(25), 3573-3588. https://doi.org/10.1016/j.jacc.2026.03.054
    • Verdonschot, J. A. J., Van Spaendonck-Zwarts, K. Y., Hellebrekers, D. M. E., Asselbergs, F. W., Behr, E. R., Charron, P., Dawson, D., Garcia-Pavia, P., Haugaa, K. H., Jurcut, R., Kuchynka, P., Lopes, L. R., Mazzanti, A., Metra, M., Monserrat, L., Kaski, J. P., Pantazis, A., Prasad, S. K., Rosano, G., ... Van Tintelen, J. P. (2026). Genetic counselling implementation in dilated cardiomyopathy: A clinical consensus statement of the Heart Failure Association of the ESC, the ESC Working Group on Myocardial and Pericardial Diseases, and the ESC Council on Cardiovascular Genomics. European Heart Journal, 47(24), 3040-3051. https://doi.org/10.1093/eurheartj/ehag159
    • Sliwa, K., Verdonschot, J. A. J., Hoevelmann, J., Macera, F., Cowley, B., Schamroth, A., de Marvao, A., Mbakwem, A., Farhan, H. A., Sensini, L., & Bauersachs, J. (2026). Cardio-obstetrics care: challenging scenarios in heart failure and future directions. European journal of heart failure. https://doi.org/10.1093/ejhf/xuag175
    • Bianchi, L., Afonso, L., Chendey, T., Modumudi, S., Minghini, A., Verdonschot, J. A. J., & Heymans, S. R. B. (2026). Efficacy and safety of sodium-glucose cotransporter inhibitors in hypertrophic cardiomyopathy: a systematic review. IJC Heart and Vasculature, 64, Article 101906. https://doi.org/10.1016/j.ijcha.2026.101906
    • Sikking, M. A., Peisker, F., Maatz, H., Lopez-Anguita, N., Hazebroek, M. R., Henkens, M. T. H. M., Raafs, A. G., Heymans, A. B. M., Stroeks, S. L. V. M., Abdul Hamid, M. A., Li, X., Vicenzetto, C., Caforio, A. L. P., Brunner-La Rocca, H.-P., Knackstedt, C., van Paassen, P., van Empel, V. P. M., Hubner, N., Verdonschot, J. A. J., & Heymans, S. R. B. (2026). Improved outcome up to 10 years after intravenous immunoglobulin therapy in patients with dilated cardiomyopathy. European journal of heart failure. Advance online publication. https://doi.org/10.1093/ejhf/xuag134
    • Di Feo, M. F., Paramonov, I., Borrel, L. M., Töpf, A., Hoischen, A., Beltran, S., Graessner, H., Vissers, L., de Voer, R., van Gijn, M., Balestrini, S., Lerche, H., Lesca, G., Gayathri, S. N., Ellwanger, K., Cossee, M., Perrin, A., Sarkozy, A., Bonne, G., ... SOLVE-RD Consortium (2026). The burden of TTN variants in the genomic era: analysis of 18,462 individuals from the Solve-RD consortium and general recommendations. Genetics in Medicine, 28(6), Article 101649. https://doi.org/10.1016/j.gim.2025.101649
    • Baggio, C., Cannata, A., Gasperetti, A., Ammirati, E., Gentile, P., Peretto, G., Savonitto, G., Cecere, A., Collini, V., Sikking, M., Mistrulli, R., Pagannone, E., Rossi, V. A., Schmidt, D., Compagnucci, P., Casella, M., Artico, J., Ciabatti, M., Fabris, E., ... Marco, M. (2026). Insights Into the Natural History of Recurrent Myocarditis, A Multicenter International Study (Re-Myo Study). Journal of the American Heart Association, 15(10), Article e046767. https://doi.org/10.1161/JAHA.125.046767
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