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Catheter treatment is not only effective, but also cost-effective for ischemic stroke

Catheter treatment is not only effective, but also cost-effective for ischemic stroke

29 September 2026

With ischemic stroke, every minute counts. However, many patients do not seek hospital care until it is too late, for example, because symptoms are not immediately recognized or because people wake up with signs of neurological deficits. As a result, a group of patients is no longer eligible for catheter treatment. 

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Platelets: more than a band-aid

Platelets: more than a band-aid

23 September 2026

Some processes in our body might seem obvious to us. If you cut your finger, the bleeding will stop shortly and form a scab. Behind that seemingly simple process hides a sophisticated system of platelets and clotting factors. By now, we know that platelets do much more than halt bleeding: they function as information carriers and regulators of disease processes. 

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Carim Maastricht
Carim Maastricht

Joachim Jankowski

Professor

Joachim Jankowski is an internationally recognised scientist whose pioneering work has substantially advanced vascular biology, molecular cardiovascular and cardiorenal research. He currently serves as Professor and Director of the Institute for Molecular Cardiovascular Research (IMCAR) at University Hospital RWTH Aachen. Before joining RWTH Aachen, he pursued a highly productive academic career in research and teaching at Charité - Universitätsmedizin Berlin. Trained in the natural sciences and holding a doctorate (Dr. rer. nat.), he has established internationally visible expertise in chromatographic separation, mass spectrometry and advanced analytical methods for isolating, identifying and functionally characterising endogenous cardiovascular mediators. His research bridges analytical biochemistry, nephrology, vascular biology and cardiovascular medicine and has generated new mechanistic concepts, biomarkers, therapeutic targets and treatment strategies for chronic kidney and cardiovascular disease. He has established highly visible interdisciplinary and international collaborations and successfully coordinated major research networks, including the DFG-funded SFB/TRR219 and SFB1739, as well as Marie Skłodowska-Curie Innovative Training Networks CaReSyAn (Aachen) and Lipidbrigt (UM). Joachim is founder of the “Aachen-Maastricht Institute for Cardiorenal research (AMICARE). Through his scientific leadership, translational focus and strong commitment to mentoring, he has made lasting contributions to cardiorenal research in Europe.

His research focuses on the molecular mechanisms linking chronic kidney disease to cardiovascular disease and other systemic disorders. Key topics include uremic toxins, post-translational protein modifications, vasoactive peptides, vascular calcification, cardiac remodeling, inflammation and inter-organ crosstalk. The laboratory combines high-resolution mass spectrometry, proteomics, peptidomics, metabolomics, lipidomics and mass-spectrometry imaging with cell and animal models and deeply phenotyped patient cohorts. The overarching goal is to identify causal mediators, clinically useful biomarkers and new therapeutic targets. Current work is embedded in major collaborative programs, including the DFG-funded SFB/TRR219 on cardiovascular complications in chronic kidney disease, SFB1739 on periodontal remodeling in systemic disease, SFB1382 on gut-liver communication, and KFO5011/InteraKD on acute kidney injury. Additional projects address peptide-based therapies, prevention of pathogenic protein modifications and multi-omics strategies for precision medicine in kidney and cardiovascular disease.

Joachim jankowski 6a959425a284c

Department of Pathology

Phone number: +49 241 80 -80580

  • 2026
    • Vondenhoff, S., Antwerpen, A., Junho, C. V. C., Martin, P., Hourtz, S., Zou, J., Kurt, B., Haas, C., Fleig, S., Schulte, C., Lauxen, J., Wessiepe, M., Späte-Schulze, U., Kramann, R., Floege, J., Soehnlein, O., Jankowski, J., Goettsch, C., Döring, Y., ... Noels, H. (2026). Immature Neutrophil Phenotype and Enhanced Myeloperoxidase in Male Patients With Chronic Kidney Disease and Cardiovascular Comorbidity. Acta Physiologica, 242(9), Article e70290. https://doi.org/10.1111/apha.70290
    • Öztürk, B. Y., Zhang, L., von Stillfried, S., Klinkhammer, B. M., Möllmann, J., Nguyen, L., Droste, P., Buhl, E. M., Hohl, M., Noels, H., Jankowski, V., Jankowski, J., Goettsch, C., Marx, N., Olson, L. E., Rosenkranz, S., Floege, J., Wong, D. W. L., & Boor, P. (2026). The role of platelet-derived growth factor in uremic vascular calcification. Kidney International, 110(3), 643-663. https://doi.org/10.1016/j.kint.2026.05.011
    • Junho, C. V. C., Dai, Y., Schieren, L., Hourtz, S., Rykova, T., Vondenhoff, S., Wessiepe, M., Zou, J., Jankowski, J., Goettsch, C., & Noels, H. (2026). Advanced glycation end product (AGE)-modified albumin does not enhance neutrophil extracellular trap formation and minimally impacts endothelial inflammation in large vessels. Life Sciences, 398, Article 124467. https://doi.org/10.1016/j.lfs.2026.124467
    • Jankowski, J., & Wu, Z. (2026). Paraspeckles, ferroptosis, and cardiac hypertrophy: a new axis in heart failure biology. European Heart Journal, Article ehag207. https://doi.org/10.1093/eurheartj/ehag207
    • Niederau, C., Ali, A. A., Chahboun, S., Kalim, S., Portillo, M. R., Kramann, R., Schulze-Späte, U., Wolfart, S., Jankowski, J., Wolf, M., & Craveiro, R. B. (2026). Oral Health in Early and Advanced Stages (1-4) of Chronic Kidney Disease: A Systematic Review and Meta-Analysis. International Dental Journal, 76(4), Article 109610. https://doi.org/10.1016/j.identj.2026.109610
    • Schulte, C., Wollenhaupt, J., Hourtz, S., Harlacher, E., Moellmann, J., Junho, C. V. C., Kohlhaas, M., Jankowski, V., Jin, H., Reugels, M., Maryam, S., Hausmann, F., Wong, D. W. L., van der Vorst, E. P. C., Berger, M., Vondenhoff, S., Kurt, B., Ghesquiere, B., Mueller, C., ... Noels, H. (2026). CKD disrupts cardiac energy metabolism and aggravates cardiac inflammation, oxidative stress, and dysfunction post-infarction. Cardiovascular Research, 122(13), 1834–1850. https://doi.org/10.1093/cvr/cvag152
    • Wolf, M., Schulze-Spate, U., Van Dyke, T., Wolfart, S., Dietrich, T., Ortiz, A., Wu, Z., & Jankowski, J. (2026). Impact of systemic diseases on periodontal remodeling: Mechanisms, mediators, and clinical relevance. Periodontology 2000. https://doi.org/10.1111/prd.70048
    • Huchzermeier, R., de Jong, R. J., Rakateli, L., Bonnin-Marquez, A., Maas, S. L., Maassen-Pottgens, C., Abschlag, K., Jin, H., Geiselhoringer, A.-L., Triantafyllidou, V., Santovito, D., Jankowski, J., Biessen, E. A. L., Ohnmacht, C., & van der Vorst, E. P. C. (2026). Whole-Body Knockout of the AhR (Aryl Hydrocarbon Receptor) Ameliorates Atherosclerosis Due to Altered Lipid Metabolism-Brief Report. Arteriosclerosis Thrombosis and Vascular Biology, 46(3), Article e323673. https://doi.org/10.1161/ATVBAHA.125.323673
    • de Vries, J. C., Bras, J. G., de Vries, G. M., Vollenbroek, J. C., Wieringa, F. P., Jankowski, J., Verhaar, M. C., Stamatialis, D., Masereeuw, R., & Gerritsen, K. G. F. (2026). Strategies for Removal of Protein-Bound Uremic Toxins in Hemodialysis. Toxins, 18(1), Article 57. https://doi.org/10.3390/toxins18010057
    • Mikolajetz, D., Kalim, S., Noels, H., Wu, Z., Jankowski, V., Jankowski, J., & de la Puente-secades, S. (2026). Impact of amino acid supplementation on cardiovascular and chronic kidney diseases: a systematic review. Cardiovascular Research, 122(2), 178-194. https://doi.org/10.1093/cvr/cvag007
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