Menu

Latest news & events

Catheter treatment is not only effective, but also cost-effective for ischemic stroke

Catheter treatment is not only effective, but also cost-effective for ischemic stroke

29 September 2026

With ischemic stroke, every minute counts. However, many patients do not seek hospital care until it is too late, for example, because symptoms are not immediately recognized or because people wake up with signs of neurological deficits. As a result, a group of patients is no longer eligible for catheter treatment. 

Read more
Platelets: more than a band-aid

Platelets: more than a band-aid

23 September 2026

Some processes in our body might seem obvious to us. If you cut your finger, the bleeding will stop shortly and form a scab. Behind that seemingly simple process hides a sophisticated system of platelets and clotting factors. By now, we know that platelets do much more than halt bleeding: they function as information carriers and regulators of disease processes. 

Read more
More newsMore events
Carim Maastricht
Carim Maastricht

Jean Scheijen

Technical staff

Jean Scheijen is an Analytical Scientist at the Department of Internal Medicine, where he focuses on analytical method development and the application of advanced analytical techniques in biomedical research.

His expertise lies particularly in UPLC-MS/MS, with extensive experience in developing, optimising, and validating analytical methods for the analysis of biomolecules and advanced glycation endproducts (AGEs). His work combines mass spectrometry-based approaches with clinical and translational research, supporting investigations into metabolic disorders, diabetes, and cardiovascular disease.

He obtained his PhD for his research on 'The analysis of advanced glycation endproducts, a mass spectrometry based approach and its applications'. Over the course of his career, he has developed and implemented a broad range of LC-MS and UPLC-MS/MS methods, contributing to the advancement of quantitative analytical techniques within biomedical research.

Department of Internal Medicine
Universiteitssingel 50, 6229 ER Maastricht, B5.334-B

  • 2026
    • van der Taelen, L., Lambrichts, S. M. P., Temmerman, L., El Ajjouri, R., Gijbels, M. J., Bitsch, N., Scheijen, J., van de Waarenburg, M., Kutmon, M., Unger, T., Staals, J., Schalkwijk, C. G., Briones, A. M., van Oostenbrugge, R. J., & Foulquier, S. (2026). Longitudinal Profiling Reveals Divergent Kidney and Brain Immune Responses during Metabolic Syndrome. Aging and Disease. Advance online publication. https://doi.org/10.14336/AD.2026.0557
    • Buziau, A. M., Simons, N., Tolan, D. R., Caiment, F., Scheijen, J. L. J. M., van de Waarenburg, M. P., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2026). Endogenous fructose production in patients and mice with aldolase B deficiency. Molecular Genetics and Metabolism, 149(1-2), Article 110219. https://doi.org/10.1016/j.ymgme.2026.110219
    • Ferrero, G., Mastrocola, R., Tarallo, S., Pardini, B., Scheijen, J., Van De Waarenburg, M., Gallo, G., Chatziioannou, A. C., Robinot, N., Keski-Rahkonen, P., Piccinno, G., Segata, N., Aglago, E. K., Hughes, D. J., Jenab, M., Schalkwijk, C. G., & Naccarati, A. (2026). Integrative analyses of dicarbonyls and advanced glycation end-products with multiomic profiles across tissue, plasma and stool samples reveal methylglyoxal accumulation in colon cancer. Free Radical Biology and Medicine, 246, 518-530. https://doi.org/10.1016/j.freeradbiomed.2026.01.034
    • Silvares, R. R., de Araujo, B. P., Pereira, E. N. G. D. S., Rodrigues, K. L., Barbosa, J. M. C., da Silva, J. F., da Silva, V. V. D., Van de Aarenburg, M., Scheijen, J., Wouters, K., Schalkwijk, C., & Daliry, A. (2026). Pyridoxamine reduces inflammatory and microcirculatory abnormalities in metabolic dysfunction-associated steatohepatitis and modulates key factors in the hepatic AGE/ALE signaling pathway. Frontiers in physiology, 16, Article 1736221. https://doi.org/10.3389/fphys.2025.1736221
  • 2025
    • van Oeteren, M. A. J., De Groot, D. M., Buziau, A. M., Scheijen, J. L. J. M., van de Waarenburg, M. P. H., Kroon, A. A., Eussen, S. J. P. M., Dagnelie, P. C., Van Greevenbroek, M. M. J., Houben, A. J. H. M., Meex, S. J. R., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2025). The effects of dietary fructose on blood pressure are modified by the food matrix. Clinical Nutrition, 55, 134-140. https://doi.org/10.1016/j.clnu.2025.10.017
    • Lasfar, A., van Stratum, S. L. M., Imperatrice, M., van Kalkeren, C. A. J., Scheijen, J. L. J. M., Schalkwijk, C. G., La Torre, D., & Troost, F. J. (2025). Effects of olive leaf extract supplementation on systemic markers of tissue aging and remodeling in postmenopausal women: a randomized controlled trial with exploratory skin outcomes. Frontiers in nutrition, 12, Article 1670194. https://doi.org/10.3389/fnut.2025.1670194
    • Mayen, A.-L., Maasen, K., Hana, C., Knaze, V., Scheijen, J., Eussen, S. J. P. M., Vangrieken, P., Debras, C., Blanco, J., Dahm, C. C., Aleksandrova, K., Schulze, M. B., Dansero, L., Masala, G., Panico, S., Sieri, S., Guevara, M., Moreno Iribas, C., Petrova, D., ... Jenab, M. (2025). Higher intakes of dietary dicarbonyl compounds are associated with lower risk of cardiovascular disease. European Journal of Preventive Cardiology, 32(16), 1588-1600. Article zwaf060. https://doi.org/10.1093/eurjpc/zwaf060
    • Akinrimisi, O. I., Koning, M., Scheijen, J. L. J. M., Meijnikman, A. S., Sindhunata, D. P., Bruin, S., van de Laar, A., Franken, R., Acherman, Y., Gerdes, V. E. A., Nieuwdorp, M., Schalkwijk, C. G., & Hanssen, N. M. J. (2025). Higher plasma dicarbonyl levels are associated with liver fibrosis in obese individuals. Diabetes Obesity & Metabolism, 27(10), 5878-5888. https://doi.org/10.1111/dom.16643
    • Van den Eynde, M. D. G., van der Bruggen, M. M., Houben, A. J. H. M., Reesink, K. D., Spronck, B., Delhaas, T., Scheijen, J. J. L. J. M., Miyata, T., & Schalkwijk, C. G. (2025). Pyridoxamine does not reduce arterial stiffness in an 8-week randomized double-blind placebo-controlled intervention trial with abdominally obese individuals. Diabetes Obesity & Metabolism, 27(9), 5332-5336. https://doi.org/10.1111/dom.16524
    • Pencheva, M. G., Berends, E., van der Laan, K. W. F., Giudici, A., Niessen, P., Scheijen, J. L. J. M., Vangrieken, P., Leenders, P., Delhaas, T., Caiment, F., Kutmon, M., Trujillo, F. M., Wouters, K., Foulquier, S., Spronck, B., Reesink, K. D., & Schalkwijk, C. G. (2025). Glyoxalase-1 overexpression attenuates arterial wall stiffening in diabetic mice. Cardiovascular Diabetology, 24(1), Article 283. https://doi.org/10.1186/s12933-025-02823-4
Overview