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Uyên Châu Nguyên wins UM Dissertation Prize 2025

Uyên Châu Nguyên wins UM Dissertation Prize 2025

29 January 2026

During the Dies Natalis of Maastricht University, Uyên Châu Nguyên received the UM Dissertation Prize 2025.

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Global research network launched to study menopause and heart health

Global research network launched to study menopause and heart health

20 January 2026

Ten international health research funders, including the Dutch Heart Foundation, are investing $10 million in a new global research network to improve early prevention of cardiovascular disease in women. The initiative focuses on understanding how menopause affects heart health and how early intervention can reduce risk.

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Carim Maastricht
Carim Maastricht

Floor Heubel-Moenen

Post doc

Dr Floor Heubel-Moenen is an internist-hematologist and postdoctoral researcher at Maastricht University Medical Center+ (MUMC+), where she works within the Hemophilia Treatment Center (HBC) and the NFU-recognized Expertise Center for Hemophilia and Allied Bleeding Disorders. Her clinical and research focus lies in improving diagnostics and care for patients with mild or unexplained bleeding symptoms. Floor graduated in Medicine at Maastricht University and completed her specialist training in Internal Medicine and Hematology at MUMC+. She obtained her PhD in 2022 with her thesis ‘Diagnostics and Mechanisms of Hemostasis in patients with mild bleeding disorders and thrombocytopenia’, at Maastricht University. Her research focused on developing and validating novel diagnostic approaches for patients with mild bleeding disorders and unexplained bleeding.

Dr Floor Heubel-Moenen’s research line is firmly rooted in daily clinical practice. Starting from unmet diagnostic needs observed during outpatient consultations, she works to identify gaps in current diagnostic algorithms and translates these questions into targeted laboratory research. Her work spans from clinical phenotyping and standardized bleeding assessment tools to advanced hemostasis assays such as thrombin generation, ROTEM, and flow-based platelet function analysis. In recognition of this translational approach, she was awarded a Translate2Clinic Fellowship in 2024 by Maastricht University. This internal, competitive program supports researchers in bridging the gap between fundamental research and clinical implementation. The fellowship has support to expand her research line, supervise students, and translate innovation from bench to bedside. Floor coordinates the national multicenter BDUC-iN study and is an active member of the ISTH Scientific Subcommittee on von Willebrand Disease and BDUC. She collaborates with national and international experts to define BDUC as a distinct clinical entity and explore pathways for ICD-code recognition. She also contributes to national guideline development and co-leads educational initiatives on bleeding disorders. Through her combined role in clinical care, diagnostics, and translational research, she aims to build a sustainable line of innovation that improves the diagnostic process and personalized treatment of patients with bleeding symptoms.

Portretfoto floor

Department of Internal Medicine - Hematology 
Maastricht UMC+, P. Debyelaan 25, 6229 HX Maastricht
T: +31(0)43 387 7976

  • 2025
    • Monard, A. L. L., Hellenbrand, D., Verhezen, P., Beckers, E. A. M., Henskens, Y. C. M., & Heubel-Moenen, F. C. J. I. (2025). tPA-ROTEM identifies hyperfibrinolytic profile in a significant proportion of patients with bleeding disorder of unknown cause (BDUC). Thrombosis Research, 253, Article 109404. https://doi.org/10.1016/j.thromres.2025.109404
    • Atiq, F., Blok, R., van Kwawegen, C., Hulshof, A.-M., Doherty, D., Lavin, M., van der Bom, J. G., O'Connell, N. M., de Meris, J., Ryan, K., Schols, S. E. M., van Heerde, W. L., Doyle, M. M., Byrne, M. B., Heubel-Moenen, F. C. J. I., van Galen, K. P. M., Preston, R. J. S., Cnossen, M. H., Fijnvandraat, K., ... O'Donnell, J. S. (2025). Clinical phenotype and pathophysiological mechanisms underlying qualitative Low VWF. Blood, 146(3), 369-381. https://doi.org/10.1182/blood.2024028035
    • Monard, A., Henskens, Y., & Heubel-Moenen, F. (2025). The diagnostic value of the platelet function analyzer in mild to moderate bleeding disorders. Journal of Thrombosis and Haemostasis, 23(7), 2116-2118. https://doi.org/10.1016/j.jtha.2025.03.041
    • Mussert, C. M. A., Monard, A. L. L., van Duijl, T. T., Henskens, Y. M. C., van den Biggelaar, M., Schutgens, R. E. G., Schols, S. E. M., Fijnvandraat, K. J., Meijer, K., den Exter, P. L., Nieuwenhuizen, L., van Moort, I., Kruip, M. J. H. A., Cnossen, M. H., Heubel-Moenen, F. C. J. I., & BDUC-iN Study group (2025). Current Practice Regarding Bleeding Disorders of Unknown Cause in the Netherlands: A National Survey. Haemophilia, 31(4), 752-760. https://doi.org/10.1111/hae.70065
    • Mansouritorghabeh, H., Monard, A., Heubel-Moenen, F., Leentjens, J., Stroobants, A., & Henskens, Y. (2025). The Utility of Total Thrombus-Formation Analysis System (T-TAS) in the Thrombosis and Hemostasis Field: A Scoping Review. International Journal of Laboratory Hematology, 47(2), 201-211. https://doi.org/10.1111/ijlh.14403
    • van Kwawegen, C. B., Pastoor, H., Eikenboom, J., Fijnvandraat, K., Ypma, P., Heubel-Moenen, F. C. J. I., van Galen, K. P. M., Mauser-Bunschoten, E. P., Meijer, K., Schols, S. E. M., Cnossen, M. H., van der Bom, J. G., de Meris, J., Atiq, F., Kruip, M. J. H. A., Leebeek, F. W. G., & WiN Study Group (2025). Sexuality and bleeding in von Willebrand disease. Research and practice in thrombosis and haemostasis, 9(2), Article e102712. https://doi.org/10.1016/j.rpth.2025.102712
    • van der Zwet, K., de Vos, A. D. W., Cnossen, M. H., Heubel-Moenen, F. C. J. I., Schols, S. E. M., Ypma, P. F., den Exter, P. L., Hooimeijer, H. L., Coppens, M., Mathôt, R. A. A., Janssen, A., Donners, A. A. M. T., Kruis, I., Urbanus, R. T., van Vulpen, L. F. D., Eckhardt, C. L., Schutgens, R. E. G., Fischer, K., Cnossen, M. H., ... Schutgens, R. E. G. (2025). Pharmacokinetic-guided dose reduction of emicizumab in congenital hemophilia A: interim analysis of the DosEmi study. Journal of Thrombosis and Haemostasis. Advance online publication. https://doi.org/10.1016/j.jtha.2025.10.029
  • 2024
    • Jooss, N. J., Diender, M. G., Fernandez, D. I., Huang, J., Heubel-Moenen, F. C. J., van der Veer, A., Kuijpers, M. J. E., Poulter, N. S., Henskens, Y. M. C., te Loo, M., & Heemskerk, J. W. M. (2024). Restraining of glycoprotein VI- and integrin α2β1-dependent thrombus formation by platelet PECAM1. Cellular and Molecular Life Sciences, 81(1), Article 44. https://doi.org/10.1007/s00018-023-05058-2
    • Monard, A. L. L., Mussert, C. M. A., van Duijl, T. T., Kruip, M. J. H. A., Henskens, Y. M. C., van den Biggelaar, M., Schutgens, R. E. G., Schols, S. E. M., Fijnvandraat, K. J., Meijer, K., den Exter, P. L., Nieuwenhuizen, L., van Moort, I., Baker, R. I., O'Donnell, J. S., Cnossen, M. H., Heubel-Moenen, F. C. J. I., & BDUC-iN Study group (2024). Bleeding disorder of unknown cause: an illustrated review on current practice, knowledge gaps, and future perspectives. Research and practice in thrombosis and haemostasis, 8(8), Article 102625. https://doi.org/10.1016/j.rpth.2024.102625
    • Monard, A., Castoldi, E., De Simone, I., Wichapong, K., van Duijl, T., van den Biggelaar, M., Spada, S., van Doorn, W., Hellenbrand, D., van der Meijden, P., Swieringa, F., Stork, A., ten Cate, H., Beckers, E., Heubel-Moenen, F., & Henskens, Y. (2024). Case Report: Laboratory detection of a thrombotic tendency in a family with hypodysfibrinogenemia and a novel FGG mutation. Frontiers in Cardiovascular Medicine, 11, Article 1488602. https://doi.org/10.3389/fcvm.2024.1488602
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