Elisabetta Castoldi
Associate professor
Dr. Elisabetta Castoldi was trained in molecular genetics at Ferrara University (Italy), where she graduated in Biology (1996) and completed a PhD project on coagulation factor V-related disorders under the supervision of Prof. F. Bernardi (2001). She then moved to Maastricht University (The Netherlands) for post-doctoral training in coagulation biochemistry in Prof. J. Rosing’s laboratory. In 2006, she was awarded a Vidi grant from the Netherlands Organisation for Scientific Research (NWO), which allowed her to establish her own research line.
In collaboration with several (clinical) groups, she combines genetic and functional approaches to unravel coagulation defects that predispose to bleeding or venous thrombosis. Her main areas of expertise are factor V and the regulation of coagulation by the protein C pathway and the tissue factor pathway inhibitor system. Moreover, she is interested in the role of splicing variants of coagulation factors, such as FV-short and fibrinogen γ’, in the pathophysiology of coagulation. Besides her research activity, she is a dedicated teacher.
