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Uyên Châu Nguyên wins UM Dissertation Prize 2025

Uyên Châu Nguyên wins UM Dissertation Prize 2025

29 January 2026

During the Dies Natalis of Maastricht University, Uyên Châu Nguyên received the UM Dissertation Prize 2025.

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Global research network launched to study menopause and heart health

Global research network launched to study menopause and heart health

20 January 2026

Ten international health research funders, including the Dutch Heart Foundation, are investing $10 million in a new global research network to improve early prevention of cardiovascular disease in women. The initiative focuses on understanding how menopause affects heart health and how early intervention can reduce risk.

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Carim Maastricht
Carim Maastricht

Casper Schalkwijk

Professor

Prof. Casper Schalkwijk studied chemistry at University Utrecht and graduated in biochemistry. At the same university he obtained his PhD in 1992. He did post-graduate training in endothelial cell biology at TNO-PG in Leiden. He was appointed in 1995 as assistant professor and staff member at the Department of Clinical Chemistry at the Vrije Universiteit Medical Cente in Amsterdam and from 2004 as associate professor. He has led the Vascular Unit. He moved to the Department of Internal Medicine at Maastricht University in 2005, where he is heading the Laboratory for Metabolism and Vascular Medicine (~15fte). He was appointed as Professor of Experimental Internal Medicine at the Faculty of Health, Medicine and Life Sciences (FHML) of Maastricht UMC+ in 2011.

His main research themes are obesity, insulin resistance, endothelial function and vascular complications. The importance of endothelial dysfunction for the development of diabetic complications is studied in epidemiological setting with the availability of several cohorts and with experimental ex-vivo -, animal - and cell work. He has led several clinical studies. A major aim of his programme is to deliver specific and sensitive diagnostic biomarkers for the identification of patients developing  type 2 diabetes and to identify patients with high risk of vascular complications. Robust analytical techniques for measurements of biomarkers with multi-array technology and with UPLC-MSMS are available. A second aim of his programme is to obtain insight in the pathophysiology of vascular complications in diabetes. His current studies focus mainly on the importance non-enzymatic glycation for the development of diabetes and diabetic complications. He discovered, as one of the first, the link between AGEs and vascular complications in individuals with and without diabetes. He is an (inter)nationally recognised expert in the field of glycation. His lab is one of the most renowned labs in this field.The work has been supported by several grants and is now granted by the Diabetes Fonds Nederland, EFSD, NWO, ZonMw and NVWA.

Casper-schalkwijk

Department of Internal Medicine
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: 5.324
T: +31(0)43 388 21 86

  • 2025
    • van Oeteren, M. A. J., De Groot, D. M., Buziau, A. M., Scheijen, J. L. J. M., van de Waarenburg, M. P. H., Kroon, A. A., Eussen, S. J. P. M., Dagnelie, P. C., Van Greevenbroek, M. M. J., Houben, A. J. H. M., Meex, S. J. R., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2025). The effects of dietary fructose on blood pressure are modified by the food matrix. Clinical Nutrition, 55, 134-140. https://doi.org/10.1016/j.clnu.2025.10.017
    • Lasfar, A., van Stratum, S. L. M., Imperatrice, M., van Kalkeren, C. A. J., Scheijen, J. L. J. M., Schalkwijk, C. G., La Torre, D., & Troost, F. J. (2025). Effects of olive leaf extract supplementation on systemic markers of tissue aging and remodeling in postmenopausal women: a randomized controlled trial with exploratory skin outcomes. Frontiers in nutrition, 12, Article 1670194. https://doi.org/10.3389/fnut.2025.1670194
    • Mayen, A.-L., Maasen, K., Hana, C., Knaze, V., Scheijen, J., Eussen, S. J. P. M., Vangrieken, P., Debras, C., Blanco, J., Dahm, C. C., Aleksandrova, K., Schulze, M. B., Dansero, L., Masala, G., Panico, S., Sieri, S., Guevara, M., Moreno Iribas, C., Petrova, D., ... Jenab, M. (2025). Higher intakes of dietary dicarbonyl compounds are associated with lower risk of cardiovascular disease. European Journal of Preventive Cardiology, 32(16), 1588-1600. Article zwaf060. https://doi.org/10.1093/eurjpc/zwaf060
    • van der Laan, K. W. F., Neutel, C. H. G., Pencheva, M. G., Wesley, C. D., Krüger, D. N., Schalwijk, C. G., De Meyer, G. R. Y., Martinet, W., Reesink, K. D., Delhaas, T., Giudici, A., Guns, P.-J., & Spronck, B. (2025). Vascular aging impairs active modulation of murine aortic stiffness by smooth muscle cells. American Journal of Physiology-Cell Physiology, 329(5), C1398-C1410. https://doi.org/10.1152/ajpcell.00387.2025
    • Chen, H., Simons, P. I. H. G., Simons, N., van de Waarenburg, M. P. H., Bons, J. A. P., van der Ploeg, E. M. C. L., Feskens, E. J. M., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2025). Effects of glucose and fructose supplementation on serum sex hormone-binding globulin and testosterone levels: post-hoc analysis of a double-blind randomized controlled trial. Clinical Nutrition ESPEN, 69, 384-388. https://doi.org/10.1016/j.clnesp.2025.07.1123
    • Akinrimisi, O. I., Koning, M., Scheijen, J. L. J. M., Meijnikman, A. S., Sindhunata, D. P., Bruin, S., van de Laar, A., Franken, R., Acherman, Y., Gerdes, V. E. A., Nieuwdorp, M., Schalkwijk, C. G., & Hanssen, N. M. J. (2025). Higher plasma dicarbonyl levels are associated with liver fibrosis in obese individuals. Diabetes Obesity & Metabolism, 27(10), 5878-5888. https://doi.org/10.1111/dom.16643
    • van der Bruggen, M. M., van Greevenbroek, M. M. J., Spronck, B., Stehouwer, C. D. A., Delhaas, T., Reesink, K. D., & Schalkwijk, C. G. (2025). Plasma reactive dicarbonyls are not independently associated with arterial stiffness: The Maastricht Study. American Journal of Hypertension, 38(10), 777-787. https://doi.org/10.1093/ajh/hpaf068
    • Hansen, E. K., Hansen, D., Schalkwijk, C., Waarenburg, M., Hansen, H. P., & Lindhard, K. (2025). The Effect of Far Infrared Treatment on Changes in Biomarkers in the Arteriovenous Fistula. Blood Purification. Advance online publication. https://doi.org/10.1159/000547478
    • Dimitropoulou, N. M., Eussen, S. J. P. M., Schalkwijk, C. G., & de Galan, B. E. (2025). Glucose variability measured by continuous glucose monitoring is associated with skin autofluorescence: the Maastricht Study. Diabetologia, 68(9), 1937-1946. https://doi.org/10.1007/s00125-025-06469-5
    • Van den Eynde, M. D. G., van der Bruggen, M. M., Houben, A. J. H. M., Reesink, K. D., Spronck, B., Delhaas, T., Scheijen, J. J. L. J. M., Miyata, T., & Schalkwijk, C. G. (2025). Pyridoxamine does not reduce arterial stiffness in an 8-week randomized double-blind placebo-controlled intervention trial with abdominally obese individuals. Diabetes Obesity & Metabolism, 27(9), 5332-5336. https://doi.org/10.1111/dom.16524
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