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Uyên Châu Nguyên wins UM Dissertation Prize 2025

Uyên Châu Nguyên wins UM Dissertation Prize 2025

29 January 2026

During the Dies Natalis of Maastricht University, Uyên Châu Nguyên received the UM Dissertation Prize 2025.

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Global research network launched to study menopause and heart health

Global research network launched to study menopause and heart health

20 January 2026

Ten international health research funders, including the Dutch Heart Foundation, are investing $10 million in a new global research network to improve early prevention of cardiovascular disease in women. The initiative focuses on understanding how menopause affects heart health and how early intervention can reduce risk.

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Carim Maastricht
Carim Maastricht

Alessandro Giudici

Post doc

Alessandro Giudici is a postdoctoral researcher in arterial mechanics. In his multidisciplinary approach to research, Alessandro integrates biomedical engineering and clinical studies to characterise changes in arterial mechanics and function associated with vascular ageing and disease.

Alessandro studied Biomedical Engineering at Politecnico di Milano (Milan, Italy), completing his BSc and MSc studies in 2014 and 2017, respectively. He spent his last year of MSc programme at the LaBS (Laboratory of Biological Structure Mechanics) at Politecnico di Milano developing and characterising a physical simulator of patients in dialysis. Alessandro undertook his PhD studies at Brunel University London (London, UK) between 2017 and 2021, investigating changes in arterial mechanics, structure and function associated with ageing and cardiovascular disease. During this period, he won the ARTERY Society (Association for Research into Arterial Structure and Physiology) Research Exchange Grant, allowing him to visit Prof Humphrey’s lab at Yale University (New Haven, Connecticut, US) to investigate layer-specific arterial mechanics. Alessandro joined the Department of Biomedical Engineering at CARIM in 2021, where he continues to use computational modelling and data analysis techniques to characterise arterial function in physiological and pathological conditions.

During his career, Alessandro has developed different analytical methods to study the arterial wall mechanical behaviour both in vivo and ex vivo. In vivo, Alessandro’s work has focused on developing techniques to assess arterial (dys)function non-invasively via ultrasound scanning and tonometry, including a method to estimate the arterial pressure waveform from ultrasound acquisitions. Ex-vivo, he developed a novel constitutive modelling framework to investigate the contribution of the three arterial layers to the macroscopic arterial wall mechanics.

Alessandro is Executive Committee member of the ARTERY Society, Editorial Board Member of Artery Research, and member of Working Group 2 of the EU COST action 18216 VascAgeNet.

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Department of Biomedical Engineering
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: H3.336
T: +31 43 388 1658

  • 2025
    • Parikh, S., Reesink, K. D., Spronck, B., Delhaas, T., & Giudici, A. (2025). Impact of Dynamic Axial Stretching on the Arterial Pulse Wave Velocity: Physical Foundation and Clinical Implications. Annals of Biomedical Engineering. https://doi.org/10.1007/s10439-025-03940-7
    • van der Laan, K. W. F., Neutel, C. H. G., Pencheva, M. G., Wesley, C. D., Krüger, D. N., Schalwijk, C. G., De Meyer, G. R. Y., Martinet, W., Reesink, K. D., Delhaas, T., Giudici, A., Guns, P.-J., & Spronck, B. (2025). Vascular aging impairs active modulation of murine aortic stiffness by smooth muscle cells. American Journal of Physiology-Cell Physiology, 329(5), C1398-C1410. https://doi.org/10.1152/ajpcell.00387.2025
    • Giudici, A., Robberechts, T., Kadziela, J., Stoenoiu, M. S., Delmotte, P., Donkers, K. M., van Leeuwen, J. E., Toubiana, L., Januszewicz, A., Januszewicz, M., Persu, A., & Spronck, B. (2025). Non-invasive evaluation of the hemodynamic significance of renal artery stenosis in fibromuscular dysplasia through quantitative image analysis. Kardiologia Polska. Advance online publication. https://doi.org/10.33963/v.phj.108870
    • Pencheva, M. G., Berends, E., van der Laan, K. W. F., Giudici, A., Niessen, P., Scheijen, J. L. J. M., Vangrieken, P., Leenders, P., Delhaas, T., Caiment, F., Kutmon, M., Trujillo, F. M., Wouters, K., Foulquier, S., Spronck, B., Reesink, K. D., & Schalkwijk, C. G. (2025). Glyoxalase-1 overexpression attenuates arterial wall stiffening in diabetic mice. Cardiovascular Diabetology, 24(1), Article 283. https://doi.org/10.1186/s12933-025-02823-4
    • Giudici, A., Grillo, A., Scalise, F., Reesink, K. D., Delhaas, T., Salvi, P., Spronck, B., & Parati, G. (2025). Beat-to-beat variability of aortic pulse wave velocity: Implications for aortic stiffness measurements. Journal of Hypertension, 43(4), 589-597. Article 3935. https://doi.org/10.1097/HJH.0000000000003935
    • Parikh, S., Wehrens, A., Giudici, A., Ganizada, B., Saraber, P., Schurgers, L., Debeij, G., Natour, E., Maessen, J., Huberts, W., Delhaas, T., Reesink, K., & Bidar, E. (2025). Interpretation of intra-operative strain differences in ascending thoracic aortic repair patients. Journal of Biomechanics, 179, Article 112447. https://doi.org/10.1016/j.jbiomech.2024.112447
    • Neutel, C. H. G., van der Laan, K. W. F., Wesley, C. D., Krueger, D. N., Pencheva, M. G., Schalkwijk, C. G., De Meyer, G. R. Y., Martinet, W., Delhaas, T., Reesink, K. D., Giudici, A., Guns, P.-J., & Spronck, B. (2025). The MAASWERP Study: An International, Comparative Case Study on Measuring Biomechanics of the Aged Murine Aorta. Pulse, 13(1), 1-10. https://doi.org/10.1159/000542694
  • 2024
    • Zanelli, S., Agnoletti, D., Alastruey, J., Allen, J., Bianchini, E., Bikia, V., Boutouyrie, P., Bruno, R. M., Climie, R., Djamaleddine, D., Gkaliagkousi, E., Giudici, A., Gopcevic, K., Grillo, A., Guala, A., Hametner, B., Joseph, J., Karimpour, P., Kodithuwakku, V., ... Charlton, P. H. (2024). Developing technologies to assess vascular ageing: a roadmap from VascAgeNet. Physiological Measurement, 45(12), Article 121001. https://doi.org/10.1088/1361-6579/ad548e
    • Giudici, A., Szafron, J. M., Ramachandra, A. B., & Spronck, B. (2024). Instability in Computational Models of Vascular Smooth Muscle Cell Contraction. Annals of Biomedical Engineering, 52(9), 2403-2416. https://doi.org/10.1007/s10439-024-03532-x
    • Parikh, S., Giudici, A., Huberts, W., Delhaas, T., Bidar, E., Spronck, B., & Reesink, K. (2024). Significance of Dynamic Axial Stretching on Estimating Biomechanical Behavior and Properties of the Human Ascending Aorta. Annals of Biomedical Engineering, 52(9), 2485-2495. https://doi.org/10.1007/s10439-024-03537-6
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