research
programs
Pathophysiology
The current research of our group focuses on the variability of the mechanisms underlying the initiation and perpetuation of AF. In various animal models (atrial fibrillation, atrial dilatation, rapid atrial pacing, heart failure) we study electrical activation patterns during AF and correlate the results to the underlying tissue architecture to better understand the relation between atrial structural characteristics (e.g. bundle architecture, fibrosis, and fatty infiltrates) and the perpetuation of AF. [more]
Participants
HEAD OF PROGRAM
Uli SchottenACADEMIC STAFF
PhD STUDENTS
TECHNICAL STAFF
Related publications
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published on 01-10-2010
"Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC) European Heart Rhythm Association; European Association for Cardio-Thoracic Surgery" -
published on 01-05-2010
Enhanced late Na(+) currents in atrial fibrillation new drug target or just an epiphenomenon? -
published on 26-10-2010
Electropathological substrate of longstanding persistent atrial fibrillation in patients with structural heart disease: epicardial breakthrough -
published on 20-07-2011
Combined blockade of early and late activated atrial potassium currents suppresses atrial fibrillation in a pig model of obstructive apnea