research
programs
Markers and makers
Our program focuses on three important themes within the realm of plaque stability research:
1. genomics strategies to identify vulnerable plaque specific biomarkers and molecular imaging tools (headed by Biessen & Daemen);
2. co-stimulatory molecules in plaque stability (headed by Lutgens);
3. leukocyte dynamics in the advanced plaque (headed by Biessen).
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Participants
HEAD OF PROGRAM
Erik BiessenACADEMIC STAFF
PhD STUDENTS
TECHNICAL STAFF
Related publications
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published on 18-11-2010
Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis -
published on 15-06-2010
HIV-1 Nef triggers macrophage fusion in a p61Hck- and protease-dependent manner -
published on 01-06-2010
Atherosclerotic lesion progression changes lysophosphatidic acid homeostasis to favor its accumulation -
published on 01-03-2010
Local atherosclerotic plaques are a source of prognostic biomarkers for adverse cardiovascular events -
published on 08-01-2010
The neuropeptide substance P mediates adventitial mast cell activation and induces intraplaque hemorrhage in advanced atherosclerosis -
published on 15-02-2010
Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile -
published on 11-05-2010
Nuclear receptor Nurr1 is expressed in and is associated with human restenosis and inhibits vascular lesion formation in mice involving inhibition of smooth muscle cell proliferation and inflammation -
published on 01-10-2011
MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure -
published on 27-07-2011
Caveolin-1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T-cell response.